Probing long bones with ultrasonic body waves

This study uses seismological principles and techniques including waveform simulations and travel time calculations to reveal the nature of ultrasoundwave propagation in long bones at small offsets (source-to-receiver distances) and times. Our experiments confirm the existence of reflected and converted body waves originating from wave interaction at the internal interfaces of a bone structure. We demonstrate that the bone ultrasound responses can be successfully simulated and properly interpreted based on a simple, horizontally layered approximation.

[1]  C. Gluer A new quality of bone ultrasound research , 2008, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[2]  Maryline Talmant,et al.  Comparison of three ultrasonic axial transmission methods for bone assessment. , 2005, Ultrasound in medicine & biology.

[3]  Gangming Luo,et al.  Ultrasound simulation in bone , 2008, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[4]  P. Laugier Quantitative ultrasound of bone: looking ahead. , 2006, Joint, bone, spine : revue du rhumatisme.

[5]  J. Reginster,et al.  Osteoporosis: a still increasing prevalence. , 2005, Bone.

[6]  John A. Orcutt,et al.  The Computation of Body Wave Synthetic Seismograms in Laterally Homogeneous Media (Paper 5R0217) , 1985 .

[7]  P. Rüegsegger,et al.  Direct Three‐Dimensional Morphometric Analysis of Human Cancellous Bone: Microstructural Data from Spine, Femur, Iliac Crest, and Calcaneus , 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[8]  Harry K. Genant,et al.  Quantitative Ultrasound: Assessment of Osteoporosis and Bone Status , 1999 .

[9]  R. Siffert,et al.  Ultrasonic bone assessment: "the time has come". , 2007, Bone.

[10]  B. Kennett,et al.  Seismic Wave Propagation in Stratified Media , 1983 .

[11]  K. Aki,et al.  Quantitative Seismology, 2nd Ed. , 2002 .

[12]  C. Langton,et al.  The Physical Measurement of Bone , 2003 .

[13]  V. Protopappas,et al.  Guided ultrasound wave propagation in intact and healing long bones. , 2006, Ultrasound in medicine & biology.

[14]  P. Moilanen,et al.  Ultrasonic guided waves in bone , 2008, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[15]  Benedikt Hallgrímsson,et al.  Three-dimensional microcomputed tomography imaging of basic multicellular unit-related resorption spaces in human cortical bone. , 2006, The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology.

[16]  P. Werner Knowledge about osteoporosis: assessment, correlates and outcomes , 2005, Osteoporosis International.

[17]  F Bonnel,et al.  Cortical and trabecular bone distribution in the femoral neck in osteoporosis and osteoarthritis. , 2008, Bone.

[18]  Yuanyuan Wang,et al.  Measurement of the dispersion and attenuation of cylindrical ultrasonic guided waves in long bone. , 2009, Ultrasound in medicine & biology.