Successful Management of Jaundice in a Dog using Therapeutic Blood Transfusion

Jaundice is a yellowish discoloration of the skin and mucous membranes caused by hyperbilirubinemia. Hyperbilirubinemia can occur due to prehepatic (usually hemolysis), posthepatic (due to obstructive or functional cholestasis), or hepatic causes. Hyperbilirubinemia in hepatic disease is caused by decreased uptake of unconjugated bilirubin and/or decreased conjugation by the hepatocytes (Sevelius, 1995) therefore, hyperbilirubinemia is usually associated with a severely impaired hepatic function.

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