Mutational Analysis of the APC/β-Catenin/Tcf Pathway in Colorectal Cancer
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Bert Vogelstein | Kenneth W. Kinzler | A. Sparks | K. Kinzler | B. Vogelstein | P. Morin | Patrice J. Morin | Andrew Sparks
[1] K. Kinzler,et al. Association of the APC tumor suppressor protein with catenins. , 1993, Science.
[2] M W Klymkowsky,et al. Anterior axis duplication in Xenopus induced by the over-expression of the cadherin-binding protein plakoglobin. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[3] K. Kinzler,et al. Clues to the pathogenesis of familial colorectal cancer. , 1993, Science.
[4] S N Thibodeau,et al. Microsatellite instability in cancer of the proximal colon. , 1993, Science.
[5] P. Soballe,et al. Mutations in beta-catenin are uncommon in colorectal cancer occurring in occasional replication error-positive tumors. , 1997, Cancer research.
[6] J. D. den Dunnen,et al. Rapid detection of translation-terminating mutations at the adenomatous polyposis coli (APC) gene by direct protein truncation test. , 1994, Genomics.
[7] P. Polakis,et al. The APC Protein and E-cadherin Form Similar but Independent Complexes with α-Catenin, β-Catenin, and Plakoglobin (*) , 1995, The Journal of Biological Chemistry.
[8] B. Herrmann,et al. Nuclear localization of β-catenin by interaction with transcription factor LEF-1 , 1996, Mechanisms of Development.
[9] K. Kinzler,et al. Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC−/− Colon Carcinoma , 1997, Science.
[10] K. Kinzler,et al. The APC gene product in normal and tumor cells. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[11] R. Moon,et al. The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3. , 1996, Genes & development.
[12] Stephen W. Byers,et al. Serine Phosphorylation-regulated Ubiquitination and Degradation of β-Catenin* , 1997, The Journal of Biological Chemistry.
[13] M. Peifer. Regulating Cell Proliferation--As Easy as APC , 1996, Science.
[14] Margaret J. Wheelock,et al. Identification of Plakoglobin Domains Required for Association with N-cadherin and α-Catenin (*) , 1995, The Journal of Biological Chemistry.
[15] Jörg Stappert,et al. β‐catenin is a target for the ubiquitin–proteasome pathway , 1997 .
[16] Bert Vogelstein,et al. APC mutations occur early during colorectal tumorigenesis , 1992, Nature.
[17] R. Brent,et al. APC binds to the novel protein EB1. , 1995, Cancer research.
[18] T. Akiyama,et al. Binding of APC to the Human Homolog of the Drosophila Discs Large Tumor Suppressor Protein , 1996, Science.
[19] K. Kinzler,et al. Absence of secretory phospholipase A2 gene alterations in human colorectal cancer. , 1995, Cancer research.
[20] P. Polakis,et al. Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[21] P. Polakis,et al. Deletion of an amino-terminal sequence beta-catenin in vivo and promotes hyperphosporylation of the adenomatous polyposis coli tumor suppressor protein , 1996, Molecular and cellular biology.
[22] W. Birchmeier,et al. E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton , 1994, The Journal of cell biology.