Helicobacter pylori Vacuolating Cytotoxin A Causes Anorexia and Anxiety via Hypothalamic Urocortin 1 in Mice

[1]  Dajiang J. Liu,et al.  Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci , 2019, Molecular Psychiatry.

[2]  J. Deussing,et al.  Stress peptides sensitize fear circuitry to promote passive coping , 2018, Molecular Psychiatry.

[3]  Emeran A. Mayer,et al.  The Brain-Gut-Microbiome Axis , 2018, Cellular and molecular gastroenterology and hepatology.

[4]  C. S. Chan,et al.  Paraventricular hypothalamic and amygdalar CRF neurons synapse in the external globus pallidus , 2018, Brain Structure and Function.

[5]  D. Drossman,et al.  Neuromodulators for Functional Gastrointestinal Disorders (Disorders of Gut-Brain Interaction): A Rome Foundation Working Team Report. , 2017, Gastroenterology.

[6]  M. Delgado-Rodríguez,et al.  Systematic review and meta-analysis. , 2017, Medicina intensiva.

[7]  S. Fukudo,et al.  Psychological effects of Helicobacter pylori‐associated atrophic gastritis in patients under 50 years: A cross‐sectional study , 2017, Helicobacter.

[8]  Y. Sanz,et al.  Influence of gut microbiota on neuropsychiatric disorders , 2017, World journal of gastroenterology.

[9]  S. Ng,et al.  Global Prevalence of Helicobacter pylori Infection: Systematic Review and Meta-Analysis. , 2017, Gastroenterology.

[10]  B. Gaszner,et al.  Melanocortin 4 receptor ligands modulate energy homeostasis through urocortin 1 neurons of the centrally projecting Edinger-Westphal nucleus , 2017, Neuropharmacology.

[11]  S. Upala,et al.  Effects of Helicobacter pylori eradication on insulin resistance and metabolic parameters: a systematic review and meta-analysis , 2017, European journal of gastroenterology & hepatology.

[12]  H. Roohafza,et al.  Association of anxiety, depression, and psychological distress in people with and without functional dyspepsia , 2016, Advanced biomedical research.

[13]  H. Roohafza,et al.  Anxiety, depression and distress among irritable bowel syndrome and their subtypes: An epidemiological population based study , 2016, Advanced biomedical research.

[14]  Yuan Yuan,et al.  Serum VacA antibody is associated with risks of peptic ulcer and gastric cancer: A meta-analysis. , 2016, Microbial pathogenesis.

[15]  M. Noda,et al.  New Insights into VacA Intoxication Mediated through Its Cell Surface Receptors , 2016, Toxins.

[16]  S. Latifi-Navid,et al.  Helicobacter pylori vacuolating cytotoxin genotypes and preneoplastic lesions or gastric cancer risk: a meta‐analysis , 2016, Journal of gastroenterology and hepatology.

[17]  John J Kim,et al.  Helicobacter pylori eradication therapy for functional dyspepsia: Systematic review and meta-analysis. , 2016, World journal of gastroenterology.

[18]  Jan Tack,et al.  Gastroduodenal Disorders. , 2016, Gastroenterology.

[19]  N. Dhurandhar,et al.  Interaction of obesity and infections , 2015, Obesity reviews : an official journal of the International Association for the Study of Obesity.

[20]  T. Moran,et al.  Anorexia nervosa as a motivated behavior: Relevance of anxiety, stress, fear and learning , 2015, Physiology & Behavior.

[21]  S. Pettersson,et al.  Helicobacter pylori infection can affect energy modulating hormones and body weight in germ free mice , 2015, Scientific Reports.

[22]  Antonio Gasbarrini,et al.  Helicobacter pylori and Extragastric Diseases , 2014, Helicobacter.

[23]  P. Enck,et al.  Review article: associations between Helicobacter pylori and obesity ‐ an ecological study , 2014, Alimentary pharmacology & therapeutics.

[24]  S. Backert,et al.  Signal transduction of Helicobacter pylori during interaction with host cell protein receptors of epithelial and immune cells , 2013, Gut microbes.

[25]  Z. Andrews.  Central mechanisms involved in the orexigenic actions of ghrelin , 2011, Peptides.

[26]  P. Whorwell,et al.  Severity in Irritable Bowel Syndrome: A Rome Foundation Working Team Report , 2011, The American Journal of Gastroenterology.

[27]  A. Asakawa,et al.  The role of CRF family peptides in the regulation of food intake and anxiety-like behavior , 2011, Biomolecular concepts.

[28]  R. Nunes‐de‐Souza,et al.  Anxiogenic and antinociceptive effects induced by corticotropin-releasing factor (CRF) injections into the periaqueductal gray are modulated by CRF1 receptor in mice , 2011, Hormones and Behavior.

[29]  I. Harvey,et al.  Randomised clinical trial: Helicobacter pylori eradication is associated with a significantly increased body mass index in a placebo‐controlled study , 2011, Alimentary pharmacology & therapeutics.

[30]  A. Prentice,et al.  Helicobacter pylori infection and circulating ghrelin levels - A systematic review , 2011, BMC gastroenterology.

[31]  E. Roubos,et al.  Leptin signaling modulates the activity of urocortin 1 neurons in the mouse nonpreganglionic Edinger-Westphal nucleus. , 2011, Endocrinology.

[32]  L. Muglia,et al.  Lipoprotein Receptor LRP1 Regulates Leptin Signaling and Energy Homeostasis in the Adult Central Nervous System , 2011, PLoS biology.

[33]  Yoshikazu Nakamura,et al.  Phospholipase C is a key enzyme regulating intracellular calcium and modulating the phosphoinositide balance. , 2010, Progress in lipid research.

[34]  M. Fujimiya,et al.  Parathyroid hormone-related protein has an anorexigenic activity via activation of hypothalamic urocortins 2 and 3 , 2010, Psychoneuroendocrinology.

[35]  Jan Tack,et al.  Gastroduodenal Disorders , 2010, The American Journal of Gastroenterology.

[36]  K. Cheng,et al.  Comparison of the anorexigenic activity of CRF family peptides. , 2009, Biochemical and biophysical research communications.

[37]  K. Hahm,et al.  The influence of the eradication of Helicobacter pylori on gastric ghrelin, appetite, and body mass index in patients with peptic ulcer disease , 2008, Journal of gastroenterology and hepatology.

[38]  L. Lix,et al.  The Manitoba IBD Cohort Study: A Population-Based Study of the Prevalence of Lifetime and 12-Month Anxiety and Mood Disorders , 2008, The American Journal of Gastroenterology.

[39]  A. Mendis,et al.  Helicobacter pylori--the latest in diagnosis and treatment. , 2008, Australian family physician.

[40]  M. Ikawa,et al.  Ghrelin deficiency does not influence feeding performance , 2008, Regulatory Peptides.

[41]  F. Schmidt.  Meta-Analysis , 2008 .

[42]  Psychological Effects , 2008 .

[43]  S. Bloom,et al.  Gut hormones and appetite control. , 2007, Gastroenterology.

[44]  A. Walf,et al.  The use of the elevated plus maze as an assay of anxiety-related behavior in rodents , 2007, Nature Protocols.

[45]  Daniel Falush,et al.  An African origin for the intimate association between humans and Helicobacter pylori , 2007, Nature.

[46]  Francis Creed,et al.  Psychosocial aspects of the functional gastrointestinal disorders. , 1999, Gastroenterology.

[47]  K. Hirota,et al.  Measurement of [Ca2+]i in whole cell suspensions using fura-2. , 2006, Methods in molecular biology.

[48]  A. Weitemier,et al.  Urocortin 1 distribution in mouse brain is strain-dependent , 2005, Neuroscience.

[49]  T. Cover,et al.  Helicobacter pylori VacA, a paradigm for toxin multifunctionality , 2005, Nature Reviews Microbiology.

[50]  Norifumi Ueda,et al.  Altered carbohydrate composition in colorectal adenomas and carcinomas: Histochemical characterization of N-acetylgalactosamine,l-fucose, and o-acetylated sialic acid , 1996, Journal of Gastroenterology.

[51]  K. Hirota,et al.  Measurement of [Ca²+]i in whole cell suspensions using fura-2. , 2005, Methods in molecular biology.

[52]  Y. Taché,et al.  Urocortins and the regulation of gastrointestinal motor function and visceral pain , 2004, Peptides.

[53]  T. Hirayama,et al.  Helicobacter pylori VacA Activates the p38/Activating Transcription Factor 2-mediated Signal Pathway in AZ-521 Cells* , 2004, Journal of Biological Chemistry.

[54]  D. Lawrence,et al.  Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein. , 2003, The Journal of clinical investigation.

[55]  K. Haruma,et al.  The long‐term effect of Helicobacter pylori eradication therapy on symptoms in dyspeptic patients with fundic atrophic gastritis , 2003, Alimentary pharmacology & therapeutics.

[56]  Kazuhide Higuchi,et al.  Long-term effect of Helicobacter pylori eradication on quality of life, body mass index, and newly developed diseases in Japanese patients with peptic ulcer disease. , 2002, Hepato-gastroenterology.

[57]  M. Fujimiya,et al.  Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin. , 2001, Gastroenterology.

[58]  永田 広.  Application of bead-ELISA method to detect Helicobacter pylori VacA , 2000 .

[59]  N. Ling,et al.  Differential distribution of urocortin- and corticotropin-releasing factor-like immunoreactivities in the rat brain , 1999, Neuroscience.

[60]  M. Kasuga,et al.  Urocortin reduces food intake and gastric emptying in lean and ob/ob obese mice. , 1999, Gastroenterology.

[61]  M. Takigawa,et al.  Glucose-sensitive neurons in the rat arcuate nucleus contain neuropeptide Y , 1999, Neuroscience Letters.

[62]  T. Hirayama,et al.  Application of Bead-ELISA method to detect Helicobacter pylori VacA. , 1999, Microbial pathogenesis.

[63]  D. Thompson,et al.  Brain-gut axis in health and disease. , 1998, Gastroenterology.

[64]  T. Hirayama,et al.  Helicobacter pylori vacuolating cytotoxin binds to the 140-kDa protein in human gastric cancer cell lines, AZ-521 and AGS. , 1997, Biochemical and biophysical research communications.

[65]  F. Hirayama,et al.  Establishment of gastric Helicobacter pylori infection in Mongolian gerbils. , 1996, Journal of gastroenterology.

[66]  R. Rappuoli,et al.  Low pH Activates the Vacuolating Toxin of Helicobacter pylori, Which Becomes Acid and Pepsin Resistant (*) , 1995, The Journal of Biological Chemistry.

[67]  A. Taylor,et al.  Psychological aspects of irritable bowel syndrome: comparisons with inflammatory bowel disease and nonpatient controls. , 1993, Behaviour research and therapy.