This is the pre-peer-reviewed version of the following article:

[1]  J. Bower,et al.  An active membrane model of the cerebellar Purkinje cell II. Simulation of synaptic responses. , 1994, Journal of neurophysiology.

[2]  M. Alonso,et al.  Hyaluronic Acid/Chitosan-g-Poly(ethylene glycol) Nanoparticles for Gene Therapy: An Application for pDNA and siRNA Delivery , 2010, Pharmaceutical Research.

[3]  C. Cho,et al.  The suppression of lung tumorigenesis by aerosol-delivered folate-chitosan-graft-polyethylenimine/Akt1 shRNA complexes through the Akt signaling pathway. , 2009, Biomaterials.

[4]  William J. Parton,et al.  Modelling soil organic matter dynamics and plant productivity in tropical ecosystems. , 1994 .

[5]  William Salas,et al.  Assessing alternatives for mitigating net greenhouse gas emissions and increasing yields from rice production in China over the next twenty years. , 2006, Journal of environmental quality.

[6]  S. Pricl,et al.  PAMAM dendrimers for siRNA delivery: computational and experimental insights. , 2010, Chemistry.

[7]  Duncan J. Watts,et al.  Collective dynamics of ‘small-world’ networks , 1998, Nature.

[8]  Zehua Wang,et al.  Chitosan/pshRNA plasmid nanoparticles targeting MDR1 gene reverse paclitaxel resistance in ovarian cancer cells , 2009, Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban.

[9]  S. Kasturi,et al.  Enhancing polysaccharide-mediated delivery of nucleic acids through functionalization with secondary and tertiary amines. , 2008, Current topics in medicinal chemistry.

[10]  Melissa J. Krauss,et al.  Characteristics and circumstances of falls in a hospital setting , 2004, Journal of General Internal Medicine.

[11]  Bartlett W. Mel,et al.  Pyramidal Neuron as Two-Layer Neural Network , 2003, Neuron.

[12]  Changsheng Li,et al.  A process-oriented model of N2O and NO emissions from forest soils: 1. Model development , 2000 .

[13]  Eben Alsberg,et al.  Localized and sustained delivery of silencing RNA from macroscopic biopolymer hydrogels. , 2009, Journal of the American Chemical Society.

[14]  James M. Bower,et al.  Python as a Federation Tool for GENESIS 3.0 , 2012, PloS one.

[15]  R. L. McCown,et al.  Changing systems for supporting farmers' decisions: problems, paradigms, and prospects , 2002 .

[16]  Sarala M. Wimalaratne,et al.  The Systems Biology Graphical Notation , 2009, Nature Biotechnology.

[17]  J. Au,et al.  Delivery of siRNA Therapeutics: Barriers and Carriers , 2010, The AAPS Journal.

[18]  Ngaire Kerse,et al.  Interventions for preventing falls in older people in nursing care facilities and hospitals. , 2010, The Cochrane database of systematic reviews.

[19]  Kenneth A Howard,et al.  RNA interference in vitro and in vivo using a novel chitosan/siRNA nanoparticle system. , 2006, Molecular therapy : the journal of the American Society of Gene Therapy.

[20]  Kuo Zhang,et al.  TAT Peptides Mediated Small Interfering RNA Delivery to Huh-7 Cells and Efficiently Inhibited Hepatitis C Virus RNA Replication , 2009, Intervirology.

[21]  T. Aminabhavi,et al.  Chitosan as a carrier for targeted delivery of small interfering RNA. , 2010, International journal of pharmaceutics.

[22]  B. Evrard,et al.  Development of pH-responsive nanocarriers using trimethylchitosans and methacrylic acid copolymer for siRNA delivery. , 2010, Biomaterials.

[23]  J. Kjems,et al.  Chitosan/siRNA Nanoparticle-mediated TNF-α Knockdown in Peritoneal Macrophages for Anti-inflammatory Treatment in a Murine Arthritis Model. , 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

[24]  Johannes Schemmel,et al.  Neuroinformatics Original Research Article Establishing a Novel Modeling Tool: a Python-based Interface for a Neuromorphic Hardware System , 2022 .

[25]  I. R. Johnson,et al.  Simulating pasture growth rates in Australian and New Zealand grazing systems , 2008 .

[26]  Perry L. Miller,et al.  Application of Technology: ModelDB: An Environment for Running and Storing Computational Models and Their Results Applied to Neuroscience , 1996, J. Am. Medical Informatics Assoc..

[27]  C. Creighton,et al.  Suppression of relaxin receptor RXFP1 decreases prostate cancer growth and metastasis. , 2010, Endocrine-related cancer.

[28]  J. Mano,et al.  hitosan derivatives obtained by chemical modifications for biomedical nd environmental applications , 2022 .

[29]  Michael L. Hines,et al.  The NEURON Book , 2006 .

[30]  Pierre Yger,et al.  PyNN: A Common Interface for Neuronal Network Simulators , 2008, Front. Neuroinform..

[31]  A. Liedloff,et al.  Modelling the effects of rainfall variability and fire on tree populations in an Australian tropical savanna with the Flames simulation model , 2007 .

[32]  P. Park,et al.  Free radical scavenging activities of differently deacetylated chitosans using an ESR spectrometer , 2004 .

[33]  Claus-Michael Lehr,et al.  In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers , 1992 .

[34]  D. Alcock,et al.  Potential effects of animal management and genetic improvement on enteric methane emissions, emissions intensity and productivity of sheep enterprises at Cowra, Australia , 2011 .

[35]  Jeong Won Lee,et al.  Targeted Gene Silencing Using RGD-Labeled Chitosan Nanoparticles , 2010, Clinical Cancer Research.

[36]  R. Waring,et al.  A generalised model of forest productivity using simplified concepts of radiation-use efficiency, carbon balance and partitioning , 1997 .

[37]  A. Bernkop‐Schnürch,et al.  Permeation enhancing polymers in oral delivery of hydrophilic macromolecules: thiomer/GSH systems. , 2003, Journal of controlled release : official journal of the Controlled Release Society.

[38]  C. White,et al.  A Meta-Analysis Evaluating the Impact of Chitosan on Serum Lipids in Hypercholesterolemic Patients , 2009, Annals of Nutrition and Metabolism.

[39]  Y. Park,et al.  Effects of the Molecular Weight and the Degree of Deacetylation of Chitosan Oligosaccharides on Antitumor Activity , 2011, International journal of molecular sciences.

[40]  Chris Moran,et al.  ASRIS: the database , 2003 .

[41]  Michael L. Hines,et al.  ModelDB: A Resource for Neuronal and Network Modeling , 2003 .

[42]  Peter J. Thorburn,et al.  OPPORTUNITIES FOR AND POTENTIAL CONSEQUENCES OF REDUCING NITROUS OXIDE EMISSIONS FROM SUGARCANE CROPS , 2010 .

[43]  Anthony N. Burkitt,et al.  A Review of the Integrate-and-fire Neuron Model: I. Homogeneous Synaptic Input , 2006, Biological Cybernetics.

[44]  R. Taylor,et al.  NATIONAL INSTITUTE FOR CLINICAL EXCELLENCE (NICE) , 2002, International Journal of Technology Assessment in Health Care.

[45]  Nicholas T. Carnevale,et al.  The NEURON Simulation Environment , 1997, Neural Computation.

[46]  J. Kjems,et al.  Intraperitoneal administration of chitosan/DsiRNA nanoparticles targeting TNFα prevents radiation-induced fibrosis. , 2010, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[47]  T. Park,et al.  Multifunctional siRNA delivery system: Polyelectrolyte complex micelles of six‐arm PEG conjugate of siRNA and cell penetrating peptide with crosslinked fusogenic peptide , 2009, Biotechnology progress.

[48]  Shuk-Mei Ho,et al.  Application of phi29 motor pRNA for targeted therapeutic delivery of siRNA silencing metallothionein-IIA and survivin in ovarian cancers. , 2011, Molecular therapy : the journal of the American Society of Gene Therapy.

[49]  Kenneth A Howard,et al.  Chitosan/siRNA nanoparticles biofunctionalize nerve implants and enable neurite outgrowth. , 2010, Nano letters.

[50]  T. Richardson,et al.  Signaling mechanisms mediating muscarinic enhancement of GABAergic synaptic transmission in the spinal cord , 2009, Neuroscience.

[51]  Edward C. Lefroy,et al.  Brave new green world - Consequences of a carbon economy for the conservation of Australian biodiversity , 2013 .

[52]  Min Huang,et al.  Uptake and Cytotoxicity of Chitosan Molecules and Nanoparticles: Effects of Molecular Weight and Degree of Deacetylation , 2004, Pharmaceutical Research.

[53]  J. Skjemstad,et al.  Calibration of the Rothamsted organic carbon turnover model (RothC ver. 26.3), using measurable soil organic carbon pools , 2004 .

[54]  Kazuyuki Yagi,et al.  Revising a process‐based biogeochemistry model (DNDC) to simulate methane emission from rice paddy fields under various residue management and fertilizer regimes , 2007 .

[55]  R. Kohn,et al.  Risk factors for falling in a psychogeriatric unit , 2001, International journal of geriatric psychiatry.

[56]  Justin H. G. Williams.  Audit of anticholinergic treatment in a psychiatric patient population , 1999 .

[57]  D. Pape,et al.  Model for estimating enteric methane emissions from United States dairy and feedlot cattle. , 2008, Journal of animal science.

[58]  J. Soussana,et al.  A review of farm level modelling approaches for mitigating greenhouse gas emissions from ruminant livestock systems , 2007 .

[59]  C. Chung,et al.  Hydrodynamic delivery of siRNA in a mouse model of sepsis. , 2008, Methods in molecular biology.

[60]  Shiro Usui,et al.  Visiome: neuroinformatics research in vision project , 2003, Neural Networks.

[61]  F. Xu,et al.  Functional gene silencing mediated by chitosan/siRNA nanocomplexes , 2009, Nanotechnology.

[62]  Forrest M Kievit,et al.  Chlorotoxin bound magnetic nanovector tailored for cancer cell targeting, imaging, and siRNA delivery. , 2010, Biomaterials.

[63]  G. Simpson,et al.  A RATING SCALE FOR EXTRAPYRAMIDAL SIDE EFFECTS , 1970, Acta psychiatrica Scandinavica. Supplementum.

[64]  J. Kjems,et al.  Direct force measurements between siRNA and chitosan molecules using force spectroscopy. , 2007, Biophysical journal.

[65]  Hsin‐Lung Chen,et al.  Enhancement of efficiencies of the cellular uptake and gene silencing of chitosan/siRNA complexes via the inclusion of a negatively charged poly(γ-glutamic acid). , 2010, Biomaterials.

[66]  Padraig Gleeson,et al.  MorphML: Level 1 of the NeuroML Standards for Neuronal Morphology Data and Model Specification , 2007, Neuroinformatics.

[67]  Qiang Yu,et al.  Modelling nitrous oxide and carbon dioxide emission from soil in an incubation experiment , 2011 .

[68]  T. Park,et al.  siRNA delivery systems for cancer treatment. , 2009, Advanced drug delivery reviews.

[69]  Örjan Ekeberg,et al.  Run-Time Interoperability Between Neuronal Network Simulators Based on the MUSIC Framework , 2010, Neuroinformatics.

[70]  I. R. Johnson,et al.  DairyMod and EcoMod: biophysical pasture-simulation models for Australia and New Zealand , 2008 .

[71]  B. Evrard,et al.  Comparison of chitosan/siRNA and trimethylchitosan/siRNA complexes behaviour in vitro. , 2010, International journal of biological macromolecules.

[72]  J. Bhathena,et al.  Ultrafine chitosan nanoparticles as an efficient nucleic acid delivery system targeting neuronal cells , 2009, Drug development and industrial pharmacy.

[73]  Peter Natesan Pushparaj,et al.  siRNA, miRNA, and shRNA: in vivo Applications , 2008, Journal of dental research.

[74]  I. R. Johnson,et al.  A generic model of growth, energy metabolism, and body composition for cattle and sheep. , 2012, Journal of animal science.

[75]  Min Huang,et al.  Uptake of FITC-Chitosan Nanoparticles by A549 Cells , 2002, Pharmaceutical Research.

[76]  P. Thorburn,et al.  Modelling nitrogen dynamics in sugarcane systems: Recent advances and applications , 2005 .

[77]  J. Mano,et al.  Chitosan-Based Particles as Controlled Drug Delivery Systems , 2004, Drug delivery.

[78]  Keith D Hill,et al.  Falls in the acute hospital setting--impact on resource utilisation. , 2007, Australian health review : a publication of the Australian Hospital Association.

[79]  J. Behr,et al.  Lipid‐mediated siRNA delivery down‐regulates exogenous gene expression in the mouse brain at picomolar levels , 2005, The journal of gene medicine.

[80]  Informing patients about tardive dyskinesia. , 1985, Archives of general psychiatry.

[81]  James M. Bower,et al.  The Book of GENESIS , 1994, Springer New York.

[82]  K. Vårum,et al.  Influence of chitosan structure on the formation and stability of DNA-chitosan polyelectrolyte complexes. , 2005, Biomacromolecules.

[83]  S Hignett,et al.  A review of environmental hazards associated with in-patient falls , 2006, Ergonomics.

[84]  P. M. Kennedy,et al.  Predicting livestock productivity and methane emissions in northern Australia: development of a bio-economic modelling approach , 2008 .

[85]  Jong-Hoon Kim,et al.  The Relationship Between Akathisia and Subjective Tolerability in Patients With Schizophrenia , 2010, The International journal of neuroscience.

[86]  Shu-lin Chen,et al.  A review on parameterization and uncertainty in modeling greenhouse gas emissions from soil , 2012 .

[87]  R. Mumper,et al.  Novel polymeric condensing carriers for gene delivery , 1995 .

[88]  M. de la Fuente,et al.  Novel hyaluronic acid-chitosan nanoparticles for ocular gene therapy. , 2008, Investigative ophthalmology & visual science.

[89]  K. Leong,et al.  The effect of the degree of chitosan deacetylation on the efficiency of gene transfection. , 2004, Biomaterials.

[90]  P. Couvreur,et al.  New Core-Shell Nanoparticules for the Intravenous Delivery of siRNA to Experimental Thyroid Papillary Carcinoma , 2010, Pharmaceutical Research.

[91]  Hiroaki Kitano,et al.  The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models , 2003, Bioinform..

[92]  Cristopher Brack,et al.  A continental biomass stock and stock change estimation approach for Australia , 2004 .

[93]  Marc-Oliver Gewaltig,et al.  NEST (NEural Simulation Tool) , 2007, Scholarpedia.

[94]  James W. Jones,et al.  Uncertainty in Simulating Wheat Yields Under Climate Change , 2013 .

[95]  A. Fire,et al.  Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans , 1998, Nature.

[96]  R. Kingwell,et al.  A comparative analysis of on-farm greenhouse gas emissions from agricultural enterprises in south eastern Australia , 2011 .

[97]  G. Barratt,et al.  Nanotechnologies and controlled release systems for the delivery of antisense oligonucleotides and small interfering RNA , 2009, British journal of pharmacology.

[98]  M. Robertson,et al.  Re-inventing model-based decision support with Australian dryland farmers. 3. Relevance of APSIM to commercial crops. , 2009 .

[99]  Michael Zimmermann,et al.  Measured soil organic matter fractions can be related to pools in the RothC model , 2007 .

[100]  Peixuan Guo,et al.  Engineering RNA for Targeted siRNA Delivery and Medical Application , 2010, Advanced Drug Delivery Reviews.

[101]  P. Morrison,et al.  The use of the Liverpool University Neuroleptic Side-Effect Rating Scale (LUNSERS) in clinical practice. , 2000, The Australian and New Zealand journal of mental health nursing.

[102]  James A. Bednar,et al.  Topographica: Building and Analyzing Map-Level Simulations from Python, C/C++, MATLAB, NEST, or NEURON Components , 2008, Front. Neuroinform..

[103]  Stephen J. Del Grosso,et al.  Impact of precipitation dynamics on net ecosystem productivity , 2012 .

[104]  Jacky L. Snoep,et al.  BioModels Database: a free, centralized database of curated, published, quantitative kinetic models of biochemical and cellular systems , 2005, Nucleic Acids Res..

[105]  Alla Borisyuk,et al.  Adaptation and inhibition underlie responses to time-varying interaural phase cues in a model of inferior colliculus neurons. , 2002, Journal of neurophysiology.

[106]  Nicolas Le Novère,et al.  SED-ML - An XML Format for the Implementation of the MIASE Guidelines , 2008, CMSB.

[107]  P. Thorburn,et al.  Using the APSIM model to estimate nitrous oxide emissions from diverse Australian sugarcane production systems. , 2010 .

[108]  Nikil D. Dutt,et al.  A configurable simulation environment for the efficient simulation of large-scale spiking neural networks on graphics processors , 2009, Neural Networks.

[109]  L. Kabasakal,et al.  Chitosan/short hairpin RNA complexes for vascular endothelial growth factor suppression invasive breast carcinoma. , 2010, Oligonucleotides.

[110]  L. Nyberg,et al.  Incidence of falls in three different types of geriatric care , 1997, Scandinavian journal of social medicine.

[111]  Corinne Le Quéré,et al.  Carbon emissions from land use and land-cover change , 2012 .

[112]  Mikael Djurfeldt.  The Connection-set Algebra—A Novel Formalism for the Representation of Connectivity Structure in Neuronal Network Models , 2012, Neuroinformatics.

[113]  Upinder S. Bhalla,et al.  PyMOOSE: Interoperable Scripting in Python for MOOSE , 2008, Frontiers in neuroinformatics.

[114]  Ram C. Dalal,et al.  Long-term trends in fertility of soils under continuous cultivation and cereal cropping in southern Queensland. IX. Simulation of soil carbon and nitrogen pools using CENTURY model , 2007 .

[115]  Avinash Dixit,et al.  Investment and Hysteresis , 1992 .

[116]  Péter Érdi,et al.  Erratum: Intrinsic and synaptic mechanisms determining the timing of neuron population activity during hippocampal theta oscillation (Journal of Neurophysiology (2006) 96 (2889-2904) DOI: 10.1152/jn.01233.2005) , 2007 .

[117]  Haliza Katas,et al.  Development and characterisation of chitosan nanoparticles for siRNA delivery. , 2006, Journal of controlled release : official journal of the Controlled Release Society.

[118]  M. Woodle,et al.  Advances in Systemic siRNA Delivery. , 2009, Drugs of the future.

[119]  Changsheng Li,et al.  Modeling carbon biogeochemistry in agricultural soils , 1994 .

[120]  E. Fattal,et al.  State of the art and perspectives for the delivery of antisense oligonucleotides and siRNA by polymeric nanocarriers. , 2008, International journal of pharmaceutics.

[121]  W. Parton,et al.  DAYCENT and its land surface submodel: description and testing , 1998 .

[122]  M. Mcmurdo,et al.  Risk factors and risk assessment tools for falls in hospital in-patients: a systematic review. , 2004, Age and ageing.

[123]  T. Kendrick,et al.  Practice nurses and the care of patients receiving depot neuroleptic treatment: views on training, confidence and use of structured assessment. , 1999, Journal of advanced nursing.

[124]  E. McCann,et al.  The subjective experiences of people who regularly receive depot neuroleptic medication in the community. , 2007, Journal of psychiatric and mental health nursing.

[125]  Leslie S. Smith,et al.  A Framework for Neural Net Specification , 1992, IEEE Trans. Software Eng..

[126]  M Hines,et al.  A program for simulation of nerve equations with branching geometries. , 1989, International journal of bio-medical computing.

[127]  J. Lam,et al.  Pulmonary delivery of therapeutic siRNA , 2011, Advanced Drug Delivery Reviews.

[128]  C. M. Sperberg-McQueen,et al.  Extensible markup language , 1997 .

[129]  J. Lynch,et al.  The turnover of organic carbon and nitrogen in soil. , 1990 .

[130]  B. Hagen,et al.  The Greater of Two Evils? How People With Transformative Psychotic Experiences View Psychotropic Medications , 2010, Ethical Human Psychology and Psychiatry.

[131]  Gaelen T. Hess,et al.  Cellular binding, motion, and internalization of synthetic gene delivery polymers. , 2007, Biochimica et biophysica acta.

[132]  Y. Duan,et al.  Cationic nano-copolymers mediated IKKβ targeting siRNA to modulate wound healing in a monkey model of glaucoma filtration surgery , 2010, Molecular vision.

[133]  M. Tabrizian,et al.  Factors influencing the transfection efficiency of ultra low molecular weight chitosan/hyaluronic acid nanoparticles. , 2009, Biomaterials.

[134]  Dan Peer,et al.  The systemic toxicity of positively charged lipid nanoparticles and the role of Toll-like receptor 4 in immune activation. , 2010, Biomaterials.

[135]  W. Zhang,et al.  Genetic Vaccines and Therapy , 2007 .

[136]  J. Kjems,et al.  Pulmonary Gene Silencing in Transgenic EGFP Mice Using Aerosolised Chitosan/siRNA Nanoparticles , 2010, Pharmaceutical Research.

[137]  M. Battaglia,et al.  CABALA: a linked carbon, water and nitrogen model of forest growth for silvicultural decision support , 2004 .

[138]  Jiabao Zhang,et al.  A spatially referenced water and nitrogen management model (WNMM) for (irrigated) intensive cropping systems in the North China Plain , 2007 .

[139]  P. Opanasopit,et al.  Chitosan-Mediated siRNA Delivery In Vitro: Effect of Polymer Molecular Weight, Concentration and Salt Forms , 2010, AAPS PharmSciTech.

[140]  Ben Berkhout,et al.  Nucleic Acids-Based Therapeutics in the Battle Against Pathogenic Viruses , 2009, Handbook of experimental pharmacology.

[141]  Mauricio Barahona,et al.  Sensory experience modifies spontaneous state dynamics in a large-scale barrel cortical model , 2012, Journal of Computational Neuroscience.

[142]  R. Wassmann,et al.  Using a Crop/Soil Simulation Model and GIS Techniques to Assess Methane Emissions from Rice Fields in Asia. I. Model Development , 2000, Nutrient Cycling in Agroecosystems.

[143]  N. Huth,et al.  Simulation of growth and development of diverse legume species in APSIM , 2002 .

[144]  C. Grainger,et al.  Options for the abatement of methane and nitrous oxide from ruminant production: A review , 2010 .

[145]  G. Edelman,et al.  Large-scale model of mammalian thalamocortical systems , 2008, Proceedings of the National Academy of Sciences.

[146]  M. A. Foale,et al.  Re-inventing model-based decision support with Australian dryland farmers. 2. Pragmatic provision of soil information for paddock-specific simulation and farmer decision making , 2009 .

[147]  Haim Sompolinsky,et al.  Chaotic Balanced State in a Model of Cortical Circuits , 1998, Neural Computation.

[148]  Steve Furber,et al.  Neural systems engineering , 2007, Journal of The Royal Society Interface.

[149]  W. Hennink,et al.  Influence of the degree of acetylation on the enzymatic degradation and in vitro biological properties of trimethylated chitosans. , 2009, Biomaterials.

[150]  Cheol-Heui Yun,et al.  Chitosan-graft-polyethylenimine for Akt1 siRNA delivery to lung cancer cells. , 2009, International journal of pharmaceutics.

[151]  N. Selvamurugan,et al.  Chitosan and its derivatives for gene delivery. , 2011, International journal of biological macromolecules.

[152]  Michael L. Hines,et al.  ModelDB - Making models publicly accessible to support computational neuroscience , 2003, Neuroinformatics.

[153]  Victoria J. Fraser,et al.  Patterns and Predictors of Inpatient Falls and Fall-Related Injuries in a Large Academic Hospital , 2005, Infection Control & Hospital Epidemiology.

[154]  Y. Kawashima,et al.  Establishing chitosan coated PLGA nanosphere platform loaded with wide variety of nucleic acid by complexation with cationic compound for gene delivery. , 2008, International journal of pharmaceutics.

[155]  A. Sood,et al.  Chitosan hydrogel for localized gene silencing , 2011, Cancer biology & therapy.

[156]  Sue Jordan,et al.  Minimizing side-effects: the clinical impact of nurse-administered 'side-effect' checklists. , 2002, Journal of advanced nursing.

[157]  W. Hennink,et al.  Reduction-sensitive polymers and bioconjugates for biomedical applications. , 2009, Biomaterials.

[158]  E. Poster,et al.  A retrospective cohort study of falls in a psychiatric inpatient setting. , 1991, Hospital & community psychiatry.

[159]  I. Kwon,et al.  Tumor targetability and antitumor effect of docetaxel-loaded hydrophobically modified glycol chitosan nanoparticles. , 2008, Journal of controlled release : official journal of the Controlled Release Society.

[160]  Y. Won,et al.  Polymer-based siRNA delivery: perspectives on the fundamental and phenomenological distinctions from polymer-based DNA delivery. , 2007, Journal of controlled release : official journal of the Controlled Release Society.

[161]  Gabriel Wittum,et al.  NeuGen: A tool for the generation of realistic morphology of cortical neurons and neural networks in 3D , 2006, Neurocomputing.

[162]  G. Dalmasso,et al.  Functional TNFα gene silencing mediated by polyethyleneimine/TNFα siRNA nanocomplexes in inflamed colon. , 2011, Biomaterials.

[163]  G. Kemmler,et al.  Prolactin Levels and Sexual Adverse Effects in Patients With Schizophrenia During Antipsychotic Treatment , 2010, Journal of clinical psychopharmacology.

[164]  Peter J. Hunter,et al.  The CellML Model Repository , 2008, Bioinform..

[165]  Yang Zhang,et al.  DC-Chol/DOPE cationic liposomes: a comparative study of the influence factors on plasmid pDNA and siRNA gene delivery. , 2010, International journal of pharmaceutics.

[166]  Erik De Schutter,et al.  NeuroSpaces: separating modeling and simulation , 2003, Neurocomputing.

[167]  W. Hennink,et al.  Gene silencing activity of siRNA polyplexes based on thiolated N,N,N-trimethylated chitosan. , 2010, Bioconjugate chemistry.

[168]  M. Sioud.  What are the key targeted delivery technologies of siRNA now? , 2010, Methods in molecular biology.

[169]  Ming Wu,et al.  Designing highly active siRNAs for therapeutic applications , 2010, The FEBS journal.

[170]  T. Segura,et al.  siRNA applications in nanomedicine. , 2010, Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology.

[171]  W. Pardridge.  shRNA and siRNA delivery to the brain. , 2007, Advanced drug delivery reviews.

[172]  Stephan Henker,et al.  Accuracy evaluation of numerical methods used in state-of-the-art simulators for spiking neural networks , 2011, Journal of Computational Neuroscience.

[173]  Romain Brette,et al.  Brian: A Simulator for Spiking Neural Networks in Python , 2008, Frontiers Neuroinformatics.

[174]  Hans Ekkehard Plesser,et al.  Visualizing Neuronal Network Connectivity with Connectivity Pattern Tables , 2009, Front. Neuroinform..

[175]  J. Cowan,et al.  Excitatory and inhibitory interactions in localized populations of model neurons. , 1972, Biophysical journal.

[176]  I. Azuma,et al.  Adjuvant activity of chitin derivatives in mice and guinea-pigs. , 1985, Vaccine.

[177]  A. Fyrberg,et al.  Optimization and evaluation of electroporation delivery of siRNA in the human leukemic CEM cell line , 2010, Cytotechnology.

[178]  Risto Miikkulainen,et al.  Scaling self-organizing maps to model large cortical networks , 2001, Neuroinformatics.

[179]  Changsheng Li,et al.  Manure-DNDC: a biogeochemical process model for quantifying greenhouse gas and ammonia emissions from livestock manure systems , 2012, Nutrient Cycling in Agroecosystems.

[180]  Mitsuo Kato,et al.  Effects of cholesterol-tagged small interfering RNAs targeting 12/15-lipoxygenase on parameters of diabetic nephropathy in a mouse model of type 1 diabetes. , 2008, American journal of physiology. Renal physiology.

[181]  Daping Quan,et al.  Cationic nano-copolymers mediated IKKβ targeting siRNA inhibit the proliferation of human Tenon’s capsule fibroblasts in vitro , 2008, Molecular vision.

[182]  Neil McKenzie,et al.  Soil Physical Measurement and Interpretation for Land Evaluation , 2002 .

[183]  W. Hennink,et al.  Gene silencing activity of siRNA polyplexes based on biodegradable polymers. , 2011, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[184]  Bo Zhu,et al.  Modeling nitrogen loadings from agricultural soils in southwest China with modified DNDC , 2011 .

[185]  P. Artursson,et al.  Chitosan and the mucosal delivery of biotechnology drugs. , 2005, Drug discovery today. Technologies.

[186]  Rodney J. Douglas,et al.  Frontiers in Computational Neuroscience , 2022 .

[187]  W. Parton,et al.  Modelling water, nitrogen, and crop yield for a long-term fallow management experiment , 1995 .

[188]  H. Kaur,et al.  A Review of Antisense Therapeutic Interventions for Molecular Biological Targets in Various Diseases , 2011 .

[189]  Michael Robertson,et al.  Prospects for ecological intensification of Australian agriculture , 2013 .

[190]  James W. Jones,et al.  The Agricultural Model Intercomparison and Improvement Project (AgMIP): Protocols and Pilot Studies , 2013 .

[191]  Klaus Schuch,et al.  PCSIM: A Parallel Simulation Environment for Neural Circuits Fully Integrated with Python , 2008, Frontiers Neuroinformatics.

[192]  Liang Dong,et al.  Selection of optimal sites for TGFB1 gene silencing by chitosan-TPP nanoparticle-mediated delivery of shRNA. , 2009, Cancer genetics and cytogenetics.

[193]  N. Wrage,et al.  Role of nitrifier denitrification in the production of nitrous oxide , 2001 .

[194]  V. Snow,et al.  Modelling the seasonal and geographical pattern of pasture production in New Zealand , 2011 .

[195]  Moritz Helias,et al.  Neuroinformatics Original Research Article Pynest: a Convenient Interface to the Nest Simulator , 2022 .

[196]  Marc-Oliver Gewaltig,et al.  Towards Reproducible Descriptions of Neuronal Network Models , 2009, PLoS Comput. Biol..

[197]  Y. Park,et al.  Leukemia-specific siRNA delivery by immunonanoplexes consisting of anti-JL1 minibody conjugated to oligo-9 Arg-peptides , 2010, Molecules and cells.

[198]  T. Sejnowski,et al.  Fluctuating synaptic conductances recreate in vivo-like activity in neocortical neurons , 2001, Neuroscience.

[199]  Yu-Kyoung Oh,et al.  siRNA conjugate delivery systems. , 2009, Bioconjugate chemistry.

[200]  Haliza Katas,et al.  Effect of preparative variables on small interfering RNA loaded Poly(D,L-lactide-co-glycolide)-chitosan submicron particles prepared by emulsification diffusion method , 2008, Journal of microencapsulation.

[201]  Jian Li,et al.  The Development and Mechanism Studies of Cationic Chitosan-Modified Biodegradable PLGA Nanoparticles for Efficient siRNA Drug Delivery , 2010, Pharmaceutical Research.

[202]  John J. Rossi,et al.  Strategies for silencing human disease using RNA interference , 2007, Nature Reviews Genetics.

[203]  Andrew D. Moore,et al.  GRAZPLAN: Decision support systems for Australian grazing enterprises. III. Pasture growth and soil moisture submodels, and the GrassGro DSS , 1997 .

[204]  Nicholas T. Carnevale,et al.  ModelDB: A Database to Support Computational Neuroscience , 2004, Journal of Computational Neuroscience.

[205]  James A. Bednar,et al.  Understanding Neural Maps with Topographica , 2008 .

[206]  A. Higgins.  Impact of psychotropic medication on sexuality: literature review. , 2007, British journal of nursing.

[207]  Marie C. M. Lin,et al.  Nucleic acid delivery with chitosan and its derivatives. , 2009, Journal of controlled release : official journal of the Controlled Release Society.

[208]  C. Rudolph,et al.  Targeted gene delivery to the lung , 2009, Expert opinion on drug delivery.

[209]  G. Marland,et al.  Depot neuroleptics, schizophrenia and the role of the nurse: is practice evidence based? A review of the literature. , 1999, Journal of advanced nursing.

[210]  Deli Chen,et al.  Simulation of N2O emissions from rain-fed wheat and the impact of climate variation in southeastern Australia , 2008, Plant and Soil.

[211]  Eugene M. Izhikevich,et al.  Which model to use for cortical spiking neurons? , 2004, IEEE Transactions on Neural Networks.

[212]  A. Boletta,et al.  Comparison between cationic polymers and lipids in mediating systemic gene delivery to the lungs , 1999, Gene Therapy.

[213]  Randal A. Koene,et al.  NETMORPH: A Framework for the Stochastic Generation of Large Scale Neuronal Networks With Realistic Neuron Morphologies , 2009, Neuroinformatics.

[214]  Nicholas T. Carnevale,et al.  Simulation of networks of spiking neurons: A review of tools and strategies , 2006, Journal of Computational Neuroscience.

[215]  Nicolas Brunel,et al.  Dynamics of Sparsely Connected Networks of Excitatory and Inhibitory Spiking Neurons , 2000, Journal of Computational Neuroscience.

[216]  J. Kjems,et al.  Naked siLNA-mediated gene silencing of lung bronchoepithelium EGFP expression after intravenous administration. , 2009, Oligonucleotides.

[217]  National Soil Carbon Research Programme: Field and Laboratory Methodologies , 2011 .

[218]  K. Minami,et al.  Nitrous oxide emissions from agricultural fields: Assessment, measurement and mitigation , 1996, Plant and Soil.

[219]  J. Kjems,et al.  Bioresponsive hyperbranched polymers for siRNA and miRNA delivery , 2010, Journal of drug targeting.

[220]  D. Giltrap,et al.  DNDC: A process-based model of greenhouse gas fluxes from agricultural soils , 2010 .

[221]  J. Bower,et al.  A Federated Design for a Neurobiological Simulation Engine: The CBI Federated Software Architecture , 2012, PloS one.

[222]  S. Moratti,et al.  The Efficacy of a Novel Chitosan Gel on Hemostasis and Wound Healing after Endoscopic Sinus Surgery , 2010, American journal of rhinology & allergy.

[223]  R. Juliano,et al.  Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides , 2008, Nucleic acids research.

[224]  Catherine M Lloyd,et al.  CellML: its future, present and past. , 2004, Progress in biophysics and molecular biology.

[225]  A. el-Sharif,et al.  Chitosan–EDTA New Combination is a Promising Candidate for Treatment of Bacterial and Fungal Infections , 2011, Current Microbiology.

[226]  R. Angus Silver,et al.  neuroConstruct: A Tool for Modeling Networks of Neurons in 3D Space , 2007, Neuron.

[227]  James W. Jones,et al.  Procedures for Initializing Soil Organic Carbon Pools in the DSSAT-CENTURY Model for Agricultural Systems , 2011 .

[228]  T. McCann,et al.  Subjective side effects of antipsychotics and medication adherence in people with schizophrenia. , 2009, Journal of advanced nursing.

[229]  W. Parton,et al.  Analysis of factors controlling soil organic matter levels in Great Plains grasslands , 1987 .

[230]  Alexander L. Miller,et al.  Role of Antipsychotic Polypharmacotherapy in the Treatment of Schizophrenia , 1999 .

[231]  A. Sood,et al.  Functional Roles of Src and Fgr in Ovarian Carcinoma , 2011, Clinical Cancer Research.

[232]  M. Coleman,et al.  An audit of psychiatric case notes in relation to antipsychotic medication and information giving. , 2000, Clinical performance and quality health care.

[233]  W. Choe,et al.  Preparation and characterization of chitosan/polyguluronate nanoparticles for siRNA delivery. , 2009, Journal of controlled release : official journal of the Controlled Release Society.

[234]  P. Opanasopit,et al.  Chitosan-Thiamine Pyrophosphate as a Novel Carrier for siRNA Delivery , 2008, Pharmaceutical Research.

[235]  Victoria J. Fraser,et al.  A case-control study of patient, medication, and care-related risk factors for inpatient falls , 2005, Journal of General Internal Medicine.

[236]  Deli Chen,et al.  Simulating response of N2O emissions to fertiliser N application and climatic variability from a rain-fed and wheat-cropped soil in Western Australia. , 2012, Journal of the science of food and agriculture.

[237]  H. Junginger,et al.  Preparation and characterization of protein-loaded N-trimethyl chitosan nanoparticles as nasal delivery system. , 2006, Journal of controlled release : official journal of the Controlled Release Society.

[238]  John M. Antle,et al.  Soil carbon sequestration rates and associated economic costs for farming systems of south-eastern Australia , 2010 .

[239]  K. Baek,et al.  Pegylated poly-l-arginine derivatives of chitosan for effective delivery of siRNA. , 2010, Journal of controlled release : official journal of the Controlled Release Society.

[240]  Changsheng Li,et al.  Modeling Trace Gas Emissions from Agricultural Ecosystems , 2000, Nutrient Cycling in Agroecosystems.

[241]  I. R. Johnson,et al.  The Sustainable Grazing Systems Pasture Model: description, philosophy and application to the SGS National Experiment , 2003 .

[242]  Mei-ying Zhang,et al.  Chitosan nanoparticles as non-viral gene delivery vehicles based on atomic force microscopy study. , 2009, Acta biochimica et biophysica Sinica.

[243]  Dean Holzworth,et al.  The Common Modelling Protocol: A hierarchical framework for simulation of agricultural and environmental systems , 2007 .

[244]  C. M. Sperberg-McQueen,et al.  Extensible Markup Language (XML) , 1997, World Wide Web J..

[245]  P. Opolon,et al.  Intravenous delivery of anti-RhoA small interfering RNA loaded in nanoparticles of chitosan in mice: safety and efficacy in xenografted aggressive breast cancer. , 2006, Human gene therapy.

[246]  Stephen M. Ogle,et al.  Predicting methanogenesis from rice paddies using the DAYCENT ecosystem model , 2013 .

[247]  C. Moreira,et al.  Improving chitosan-mediated gene transfer by the introduction of intracellular buffering moieties into the chitosan backbone. , 2009, Acta biomaterialia.

[248]  M. Zenkova,et al.  Synthesis and delivery activity of new cationic cholesteryl glucosides. , 2010, Carbohydrate research.

[249]  R. Angus Silver,et al.  Cerebellar LTD and Pattern Recognition by Purkinje Cells , 2007, Neuron.

[250]  Neil I. Huth,et al.  A framework for simulating agroforestry options for the low rainfall areas of Australia using APSIM , 2002 .

[251]  Andrew D. Moore,et al.  The GrassGro decision support tool: its effectiveness in simulating pasture and animal production and value in determining research priorities , 2000 .

[252]  Albert-László Barabási,et al.  Statistical mechanics of complex networks , 2001, ArXiv.

[253]  Tejraj M Aminabhavi,et al.  Recent advances on chitosan-based micro- and nanoparticles in drug delivery. , 2004, Journal of controlled release : official journal of the Controlled Release Society.

[254]  J. France,et al.  Evaluation of enteric methane prediction equations for dairy cows used in whole farm models , 2010 .

[255]  J. Kjems,et al.  The effect of chemical modification and nanoparticle formulation on stability and biodistribution of siRNA in mice. , 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

[256]  J. Donnelly,et al.  GRAZPLAN: Decision support systems for Australian grazing enterprises—II. The animal biology model for feed intake, production and reproduction and the GrazFeed DSS , 1997 .

[257]  S. Ollinger,et al.  Modeling nitrogen saturation in forest ecosystems in response to land use and atmospheric deposition , 1997 .

[258]  G. Borchard.  Chitosans for gene delivery. , 2001, Advanced drug delivery reviews.

[259]  Nigel H. Goddard,et al.  Towards NeuroML: model description methods for collaborative modelling in neuroscience. , 2001, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[260]  R. Simpson,et al.  Evolution of the GRAZPLAN decision support tools and adoption by the grazing industry in temperate Australia , 2002 .

[261]  Michael L. Hines,et al.  NeuroML: A Language for Describing Data Driven Models of Neurons and Networks with a High Degree of Biological Detail , 2010, PLoS Comput. Biol..

[262]  Örjan Ekeberg,et al.  Large-Scale Modeling – a Tool for Conquering the Complexity of the Brain , 2008, Frontiers Neuroinformatics.

[263]  Senthold Asseng,et al.  An overview of APSIM, a model designed for farming systems simulation , 2003 .

[264]  Andrew P. Davison,et al.  Learning from the Past: Approaches for Reproducibility in Computational Neuroscience , 2013 .

[265]  Giulio Tononi,et al.  Modeling sleep and wakefulness in the thalamocortical system. , 2005, Journal of neurophysiology.

[266]  Priti Kumar,et al.  Targeted delivery of siRNA to macrophages for anti-inflammatory treatment. , 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

[267]  R. Reznek,et al.  Increased visceral fat distribution in drug-naive and drug-free patients with schizophrenia , 2002, International Journal of Obesity.

[268]  Steve B. Furber,et al.  A General-Purpose Model Translation System for a Universal Neural Chip , 2010, ICONIP.

[269]  Jong-Hoon Kim,et al.  Association of Adverse Drug Effects With Subjective Well-Being in Patients With Schizophrenia Receiving Stable Doses of Risperidone , 2009, Clinical neuropharmacology.

[270]  Hong Yang,et al.  Inhibition of respiratory syncytial virus infection with intranasal siRNA nanoparticles targeting the viral NS1 gene , 2005, Nature Medicine.

[271]  J. Kjems,et al.  The influence of polymeric properties on chitosan/siRNA nanoparticle formulation and gene silencing. , 2007, Biomaterials.

[272]  Kwangmeyung Kim,et al.  Tumor-homing glycol chitosan/polyethylenimine nanoparticles for the systemic delivery of siRNA in tumor-bearing mice. , 2010, Journal of controlled release : official journal of the Controlled Release Society.

[273]  Shan Jiang,et al.  Quantum-dot based nanoparticles for targeted silencing of HER2/neu gene via RNA interference. , 2007, Biomaterials.

[274]  S. Haupt,et al.  Drug targeting by surface cationization. , 2000, Critical reviews in therapeutic drug carrier systems.

[275]  J. Varshosaz.  The promise of chitosan microspheres in drug delivery systems , 2007, Expert opinion on drug delivery.

[276]  S. Kapur,et al.  The Maudsley Prescribing Guidelines , 2009 .

[277]  J. Kjems,et al.  Delivery of siRNA from lyophilized polymeric surfaces. , 2008, Biomaterials.

[278]  P. Couvreur,et al.  siRNA nanoformulation against the Ret/PTC1 junction oncogene is efficient in an in vivo model of papillary thyroid carcinoma , 2007, Nucleic acids research.

[279]  D. Vlahov,et al.  Variation in Risk for Falls by Clinical Department: Implications for Prevention , 1990, Infection Control & Hospital Epidemiology.

[280]  A. Sood,et al.  Role of M2, M3, and M4 muscarinic receptor subtypes in the spinal cholinergic control of nociception revealed using siRNA in rats , 2009, Journal of neurochemistry.

[281]  Rolf Kötter,et al.  Neuroscience databases : a practical guide , 2003 .