Pathologically decreased expression of miR-193a contributes to metastasis by targeting WT1-E-cadherin axis in non-small cell lung cancers
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Bin Zhou | Kate Huang | Jianbo Wu | Chengshui Chen | Hai-ying Li | Shenmeng Gao | Chunjing Wang | Huxiang Zhang | Junjie Chen | Zhijie Yu | Zhonggai Wang
[1] E. Morii,et al. Deficiency in WT1-targeting microRNA-125a leads to myeloid malignancies and urogenital abnormalities , 2016, Oncogene.
[2] Wei Jiang,et al. Prognostic value of high FoxC2 expression in resectable non-small cell lung cancer, alone or in combination with E-cadherin expression , 2016, BMC Cancer.
[3] W. Hiddemann,et al. A 4‐gene expression score associated with high levels of Wilms Tumor‐1 (WT1) expression is an adverse prognostic factor in acute myeloid leukaemia , 2015, British journal of haematology.
[4] Xiaoying Guan,et al. MicroRNA-29b attenuates non-small cell lung cancer metastasis by targeting matrix metalloproteinase 2 and PTEN , 2015, Journal of experimental & clinical cancer research : CR.
[5] A. Zaravinos. The Regulatory Role of MicroRNAs in EMT and Cancer , 2015, Journal of oncology.
[6] Xianghuo He,et al. Quantitative Proteomic Analysis of the Metastasis-Inhibitory Mechanism of miR-193a-3p in Non-Small Cell Lung Cancer , 2015, Cellular Physiology and Biochemistry.
[7] J. Gamble,et al. miR‐181a mediates TGF‐β‐induced hepatocyte EMT and is dysregulated in cirrhosis and hepatocellular cancer , 2015, Liver international : official journal of the International Association for the Study of the Liver.
[8] Hongwei Liang,et al. miR-193a-3p Functions as a Tumor Suppressor in Lung Cancer by Down-regulating ERBB4* , 2014, The Journal of Biological Chemistry.
[9] Alfredo Hidalgo-Miranda,et al. miRNA biogenesis: Biological impact in the development of cancer , 2014, Cancer biology & therapy.
[10] Cui-ping Xu,et al. The new concepts on overcoming drug resistance in lung cancer , 2014, Drug design, development and therapy.
[11] A. Puisieux,et al. Oncogenic roles of EMT-inducing transcription factors , 2014, Nature Cell Biology.
[12] B. Liu,et al. MiR-132 Suppresses the Migration and Invasion of Lung Cancer Cells via Targeting the EMT Regulator ZEB2 , 2014, PloS one.
[13] Bob van de Water,et al. β1 Integrin Inhibition Elicits a Prometastatic Switch Through the TGFβ–miR-200–ZEB Network in E-Cadherin–Positive Triple-Negative Breast Cancer , 2014, Science Signaling.
[14] D. Rao,et al. miRNA dysregulation in cancer: towards a mechanistic understanding , 2014, Front. Genet..
[15] Lang Li,et al. Exploring a structural protein-drug interactome for new therapeutics in lung cancer. , 2014, Molecular bioSystems.
[16] Tao Yu,et al. MicroRNA-193a-3p and -5p suppress the metastasis of human non-small-cell lung cancer by downregulating the ERBB4/PIK3R3/mTOR/S6K2 signaling pathway , 2014, Oncogene.
[17] A. Gemma,et al. MiR-134/487b/655 Cluster Regulates TGF-β–Induced Epithelial–Mesenchymal Transition and Drug Resistance to Gefitinib by Targeting MAGI2 in Lung Adenocarcinoma Cells , 2013, Molecular Cancer Therapeutics.
[18] W. Gallagher,et al. miRNA dysregulation in breast cancer. , 2013, Cancer research.
[19] X. Chen,et al. Wilms’ tumour suppressor gene 1 (WT1) is involved in the carcinogenesis of Lung cancer through interaction with PI3K/Akt pathway , 2013, Cancer Cell International.
[20] Yijiang Chen,et al. WT1 Promotes Invasion of NSCLC via Suppression of CDH1 , 2013, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
[21] C. Croce,et al. MicroRNA-31 Predicts the Presence of Lymph Node Metastases and Survival in Patients with Lung Adenocarcinoma , 2013, Clinical Cancer Research.
[22] J. Xu,et al. WT1 Promotes Cell Proliferation in Non-Small Cell Lung Cancer Cell Lines through Up-Regulating Cyclin D1 and p-pRb In Vitro and In Vivo , 2013, PloS one.
[23] Xia Li,et al. A novel miR-193a-5p-YY1-APC regulatory axis in human endometrioid endometrial adenocarcinoma , 2013, Oncogene.
[24] B. Snaar-Jagalska,et al. Snail and Slug, key regulators of TGF-β-induced EMT, are sufficient for the induction of single-cell invasion. , 2013, Biochemical and biophysical research communications.
[25] Yih-Leong Chang,et al. MicroRNA-135b promotes lung cancer metastasis by regulating multiple targets in the Hippo pathway and LZTS1 , 2013, Nature Communications.
[26] J. Xiong,et al. miR-149 Inhibits Non-Small-Cell Lung Cancer Cells EMT by Targeting FOXM1 , 2013, Biochemistry research international.
[27] S. Kwak,et al. Ionizing radiation-inducible microRNA miR-193a-3p induces apoptosis by directly targeting Mcl-1 , 2013, Apoptosis.
[28] S. Tsujitani,et al. Impact of dendritic cell vaccines pulsed with Wilms' tumour-1 peptide antigen on the survival of patients with advanced non-small cell lung cancers. , 2013, European journal of cancer.
[29] M. Caligiuri,et al. Epigenetic silencing of microRNA-193a contributes to leukemogenesis in t(8;21) acute myeloid leukemia by activating the PTEN/PI3K signal pathway. , 2013, Blood.
[30] Y. Shang,et al. Epigenetic control of epithelial-to-mesenchymal transition and cancer metastasis. , 2013, Experimental cell research.
[31] M. Kitaichi,et al. Low Wilms’ Tumor Gene Expression in Tumor Tissues Predicts Poor Prognosis in Patients with Non-Small-Cell Lung Cancer , 2012, Cancer investigation.
[32] Christoph C Zielinski,et al. Genome-Wide miRNA Expression Profiling Identifies miR-9-3 and miR-193a as Targets for DNA Methylation in Non–Small Cell Lung Cancers , 2012, Clinical Cancer Research.
[33] Chong-yun Xing,et al. miR-15a and miR-16-1 inhibit the proliferation of leukemic cells by down-regulating WT1 protein level , 2011, Journal of experimental & clinical cancer research : CR.
[34] L. Gao,et al. MicroRNA-193a represses c-kit expression and functions as a methylation-silenced tumor suppressor in acute myeloid leukemia , 2011, Oncogene.
[35] P. Nelson,et al. Metastatic progression of prostate cancer and e-cadherin regulation by zeb1 and SRC family kinases. , 2011, The American journal of pathology.
[36] M. F. Shannon,et al. An autocrine TGF-β/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition , 2011, Molecular biology of the cell.
[37] S. Goodison,et al. CD24, a promising biomarker in NSCLC. , 2010, Biomarkers in medicine.
[38] M. Franco-Molina,et al. WT1 gene silencing by aerosol delivery of PEI–RNAi complexes inhibits B16-F10 lung metastases growth , 2009, Cancer Gene Therapy.
[39] Raghu Kalluri,et al. The basics of epithelial-mesenchymal transition. , 2009, The Journal of clinical investigation.
[40] S. Moriya,et al. Expression of the WT1 gene -KTS domain isoforms suppresses the invasive ability of human lung squamous cell carcinoma cells. , 2008, International journal of oncology.
[41] A. Yoshimura,et al. E-cadherin expression and epidermal growth factor receptor mutation status predict outcome in non-small cell lung cancer patients treated with gefitinib. , 2008, Oncology reports.
[42] Gema Moreno-Bueno,et al. Genetic profiling of epithelial cells expressing E-cadherin repressors reveals a distinct role for Snail, Slug, and E47 factors in epithelial-mesenchymal transition. , 2006, Cancer research.
[43] Anwar Hossain,et al. N-terminally Truncated WT1 Protein with Oncogenic Properties Overexpressed in Leukemia* , 2006, Journal of Biological Chemistry.
[44] A. Rajasekaran,et al. Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis. , 2006, Cancer research.
[45] J. Thiery,et al. Complex networks orchestrate epithelial–mesenchymal transitions , 2006, Nature Reviews Molecular Cell Biology.
[46] Yan Shen,et al. Formation of E-cadherin-mediated cell-cell adhesion activates AKT and mitogen activated protein kinase via phosphatidylinositol 3 kinase and ligand-independent activation of epidermal growth factor receptor in ovarian cancer cells. , 2005, Molecular endocrinology.
[47] A. Chávez-Reyes,et al. HER2/neu increases the expression of Wilms' Tumor 1 (WT1) protein to stimulate S-phase proliferation and inhibit apoptosis in breast cancer cells , 2005, Oncogene.
[48] D. Bartel. MicroRNAs Genomics, Biogenesis, Mechanism, and Function , 2004, Cell.
[49] Long-Cheng Li,et al. MethPrimer: designing primers for methylation PCRs , 2002, Bioinform..
[50] S. Miyoshi,et al. Overexpression of the Wilms' tumor gene WT1 in de novo lung cancers , 2002, International journal of cancer.
[51] J. Thiery. Epithelial–mesenchymal transitions in tumour progression , 2002, Nature Reviews Cancer.
[52] U. Maurer,et al. Ribozyme-mediated cleavage of wt1 transcripts suppresses growth of leukemia cells. , 2001, Experimental hematology.
[53] Keith R. Johnson,et al. N-Cadherin Promotes Motility in Human Breast Cancer Cells Regardless of Their E-Cadherin Expression , 1999, The Journal of cell biology.
[54] Y. Sonoda,et al. Aberrant overexpression of the Wilms tumor gene (WT1) in human leukemia. , 1997, Blood.
[55] T. Kudoh,et al. Growth inhibition of human leukemic cells by WT1 (Wilms tumor gene) antisense oligodeoxynucleotides: implications for the involvement of WT1 in leukemogenesis. , 1996, Blood.
[56] D. Housman,et al. Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus , 1990, Cell.
[57] A. Jemal,et al. Cancer statistics, 2016 , 2016, CA: a cancer journal for clinicians.
[58] Helen Diller Family. Targeting the TGFβ signalling pathway in disease , 2012 .
[59] 宮永 晃彦. E-cadherin expression and epidermal growth factor receptor mutation status predict outcome in non-small cell lung cancer patients treated with gefitinib , 2008 .
[60] N. Dubrawsky. Cancer statistics , 1989, CA: a cancer journal for clinicians.
[61] W. Doerfler,et al. DNA methylation and gene activity. , 1983, Annual review of biochemistry.