Untangling the Tauopathy for Alzheimer’s disease and parkinsonism
暂无分享,去创建一个
[1] R. Klausen,et al. Selective , 2020, Encyclopedia of the UN Sustainable Development Goals.
[2] Kristel Sleegers,et al. Understanding Alzheimer Disease at the Interface between Genetics and Transcriptomics. , 2018, Trends in genetics : TIG.
[3] I. Amit,et al. Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration , 2018, Cell.
[4] W. Nickel,et al. Unconventional Secretion Mediates the Trans-cellular Spreading of Tau. , 2018, Cell reports.
[5] Derek H. Oakley,et al. Synaptic Tau Seeding Precedes Tau Pathology in Human Alzheimer's Disease Brain , 2018, Front. Neurosci..
[6] J. Power,et al. Evidence for newly generated interneurons in the basolateral amygdala of adult mice , 2017, Molecular Psychiatry.
[7] D. Eisenberg,et al. Propagation of Tau Aggregates and Neurodegeneration. , 2017, Annual review of neuroscience.
[8] Arnab Ray Chaudhuri,et al. The multifaceted roles of PARP1 in DNA repair and chromatin remodelling , 2017, Nature Reviews Molecular Cell Biology.
[9] Bess Frost,et al. A Brief Overview of Tauopathy: Causes, Consequences, and Therapeutic Strategies. , 2017, Trends in pharmacological sciences.
[10] A. Murzin,et al. Cryo-EM structures of Tau filaments from Alzheimer’s disease brain , 2017, Nature.
[11] D. Knopman,et al. Alzheimer Disease: Scientific Breakthroughs and Translational Challenges , 2017, Mayo Clinic proceedings.
[12] J. Attems,et al. Interactions of pathological proteins in neurodegenerative diseases , 2017, Acta Neuropathologica.
[13] Wendy Noble,et al. Roles of tau protein in health and disease , 2017, Acta Neuropathologica.
[14] L. Aravind,et al. A conserved NAD+ binding pocket that regulates protein-protein interactions during aging , 2017, Science.
[15] S. P. Andrews,et al. Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities , 2017, Neuron.
[16] R. Boyapati,et al. Advances in the understanding of mitochondrial DNA as a pathogenic factor in inflammatory diseases , 2017, F1000Research.
[17] Geoffrey M. Barrett,et al. Tau Pathology Induces Excitatory Neuron Loss, Grid Cell Dysfunction, and Spatial Memory Deficits Reminiscent of Early Alzheimer’s Disease , 2017, Neuron.
[18] D. Hall,et al. C. elegans Neurons Jettison Protein Aggregates and Mitochondria Under Neurotoxic Stress , 2017, Nature.
[19] E. Mandelkow,et al. Additional file 5: Figure S5. of The release and trans-synaptic transmission of Tau via exosomes , 2017 .
[20] Sandra Maday. Mechanisms of neuronal homeostasis: Autophagy in the axon , 2016, Brain Research.
[21] K. Zahs,et al. Caspase-2 cleavage of tau reversibly impairs memory , 2016, Nature Medicine.
[22] S. Correia,et al. Mitochondrial traffic jams in Alzheimer's disease - pinpointing the roadblocks. , 2016, Biochimica et biophysica acta.
[23] J. Dorszewska,et al. Molecular Basis of Familial and Sporadic Alzheimer's Disease. , 2016, Current Alzheimer research.
[24] C. Graff,et al. Autophagic and lysosomal defects in human tauopathies: analysis of post-mortem brain from patients with familial Alzheimer disease, corticobasal degeneration and progressive supranuclear palsy , 2016, Acta neuropathologica communications.
[25] Eric Karran,et al. The Cellular Phase of Alzheimer’s Disease , 2016, Cell.
[26] J. Milbrandt,et al. Axon Self-Destruction: New Links among SARM1, MAPKs, and NAD+ Metabolism , 2016, Neuron.
[27] H. Arai,et al. Characteristics of Tau and Its Ligands in PET Imaging , 2016, Biomolecules.
[28] H. Wood. Alzheimer disease: Evidence for trans-synaptic and exo-synaptic tau propagation in Alzheimer disease , 2015, Nature Reviews Neurology.
[29] N. Soussi-Yanicostas,et al. Tau Hyperphosphorylation and Oxidative Stress, a Critical Vicious Circle in Neurodegenerative Tauopathies? , 2015, Oxidative medicine and cellular longevity.
[30] S. Villeda,et al. Fat Chance for Neural Stem Cells in Alzheimer's Disease. , 2015, Cell stem cell.
[31] Kewei Chen,et al. Brain Imaging and Blood Biomarker Abnormalities in Children With Autosomal Dominant Alzheimer Disease: A Cross-Sectional Study. , 2015, JAMA neurology.
[32] Tobias M. Rasse,et al. Impaired retrograde transport by the Dynein/Dynactin complex contributes to Tau-induced toxicity. , 2015, Human molecular genetics.
[33] M. Xue,et al. The Ambiguous Relationship of Oxidative Stress, Tau Hyperphosphorylation, and Autophagy Dysfunction in Alzheimer's Disease , 2015, Oxidative medicine and cellular longevity.
[34] H. Brown,et al. Microarray analysis of the in vivo response of microglia to Aβ peptides in mice with conditional deletion of the prostaglandin EP2 receptor , 2015, Genomics data.
[35] F. Coppedè,et al. DNA damage in neurodegenerative diseases. , 2015, Mutation research.
[36] Pierre J. Magistretti,et al. A Cellular Perspective on Brain Energy Metabolism and Functional Imaging , 2015, Neuron.
[37] L. Blanchoin,et al. Tau co-organizes dynamic microtubule and actin networks , 2015, Scientific Reports.
[38] M. Breakspear,et al. The connectomics of brain disorders , 2015, Nature Reviews Neuroscience.
[39] David C Rowland,et al. Place cells, grid cells, and memory. , 2015, Cold Spring Harbor perspectives in biology.
[40] J. Trojanowski,et al. Spreading of pathology in neurodegenerative diseases: a focus on human studies , 2015, Nature Reviews Neuroscience.
[41] John M. Beggs,et al. Functional Clusters, Hubs, and Communities in the Cortical Microconnectome , 2014, Cerebral cortex.
[42] D. Rubinsztein,et al. Autophagy and neurodegeneration. , 2012, The Journal of clinical investigation.
[43] T. Arendt,et al. Brain hypometabolism triggers PHF-like phosphorylation of tau, a major hallmark of Alzheimer’s disease pathology , 2015, Journal of Neural Transmission.
[44] P. Szekeres,et al. Conformation Determines the Seeding Potencies of Native and Recombinant Tau Aggregates , 2014, The Journal of Biological Chemistry.
[45] Teng Jiang,et al. Prion-like Mechanisms in Alzheimer's Disease. , 2014, Current Alzheimer research.
[46] Xinglong Wang,et al. Oxidative stress and mitochondrial dysfunction in Alzheimer's disease. , 2014, Biochimica et biophysica acta.
[47] S. Sollott,et al. Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release. , 2014, Physiological reviews.
[48] L. Grinberg,et al. Distinct Tau Prion Strains Propagate in Cells and Mice and Define Different Tauopathies , 2014, Neuron.
[49] R. Mostoslavsky,et al. Sirtuins, metabolism, and DNA repair. , 2014, Current opinion in genetics & development.
[50] J. Gilley,et al. Wallerian degeneration: an emerging axon death pathway linking injury and disease , 2014 .
[51] P. Rabinovitch,et al. Mitochondrial oxidative stress in aging and healthspan , 2014, Longevity & healthspan.
[52] L. Buée,et al. A major role for Tau in neuronal DNA and RNA protection in vivo under physiological and hyperthermic conditions , 2014, Front. Cell. Neurosci..
[53] J. Sontag,et al. Protein phosphatase 2A dysfunction in Alzheimer’s disease , 2014, Front. Mol. Neurosci..
[54] D. Holtzman,et al. Neuronal activity regulates extracellular tau in vivo , 2014, The Journal of experimental medicine.
[55] A. Mietelska-Porowska,et al. Tau Protein Modifications and Interactions: Their Role in Function and Dysfunction , 2014, International journal of molecular sciences.
[56] F. Austin,et al. Lactococcosis in Silver Carp. , 2014, Journal of aquatic animal health.
[57] M. Hemberg,et al. Tau promotes neurodegeneration through global chromatin relaxation , 2014, Nature Neuroscience.
[58] Casey Cook,et al. Acetylation of the KXGS motifs in tau is a critical determinant in modulation of tau aggregation and clearance , 2013, Human molecular genetics.
[59] Thomas Arendt,et al. Neuronal plasticity in hibernation and the proposed role of the microtubule-associated protein tau as a "master switch" regulating synaptic gain in neuronal networks. , 2013, American journal of physiology. Regulatory, integrative and comparative physiology.
[60] R. Nixon,et al. The role of autophagy in neurodegenerative disease , 2013, Nature Medicine.
[61] Dan-shen Zhang,et al. Oxidative stress, mitochondrial damage and neurodegenerative diseases , 2013, Neural regeneration research.
[62] A. Chiang,et al. Loss of vesicular dopamine release precedes tauopathy in degenerative dopaminergic neurons in a Drosophila model expressing human tau , 2013, Acta Neuropathologica.
[63] Wendy Noble,et al. Physiological release of endogenous tau is stimulated by neuronal activity , 2013, EMBO reports.
[64] E. Huang,et al. Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation , 2013, Acta Neuropathologica.
[65] A. Reyes,et al. Human mitochondrial DNA replication. , 2012, Cold Spring Harbor perspectives in biology.
[66] B. Hyman,et al. Propagation of Tau Pathology in a Model of Early Alzheimer’s Disease , 2012, Neuron.
[67] D. Attwell,et al. Synaptic Energy Use and Supply , 2012, Neuron.
[68] M. Beal,et al. Mitochondrial Dysfunction in Neurodegenerative Diseases , 2012, Journal of Pharmacology and Experimental Therapeutics.
[69] M. Goedert,et al. Stimulation of autophagy is neuroprotective in a mouse model of human tauopathy , 2012, Autophagy.
[70] H. Möller,et al. [Structural and functional neuronal connectivity in Alzheimer's disease: a combined DTI and fMRI study]. , 2012, Der Nervenarzt.
[71] S. Hébert,et al. Hypothermia-induced hyperphosphorylation: a new model to study tau kinase inhibitors , 2012, Scientific Reports.
[72] D. Řípová,et al. Structure and Pathology of Tau Protein in Alzheimer Disease , 2012, International journal of Alzheimer's disease.
[73] Jason E Gestwicki,et al. Methylthioninium chloride (methylene blue) induces autophagy and attenuates tauopathy in vitro and in vivo , 2012, Autophagy.
[74] E. Mandelkow,et al. Interaction of tau protein with model lipid membranes induces tau structural compaction and membrane disruption. , 2012, Biochemistry.
[75] Naruhiko Sahara,et al. Propagation of Tau Pathology in a Model of Early Alzheimer's Disease , 2012, Neuron.
[76] Blaine R. Roberts,et al. Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export , 2012, Nature Medicine.
[77] M. Gallagher,et al. Episodic Memory on the Path to Alzheimer's Disease This Review Comes from a Themed Issue on Neurobiology of Disease Edited , 2022 .
[78] A. McKee,et al. Exosome-associated Tau Is Secreted in Tauopathy Models and Is Selectively Phosphorylated in Cerebrospinal Fluid in Early Alzheimer Disease* , 2011, The Journal of Biological Chemistry.
[79] Dietmar R. Thal,et al. Stages of the Pathologic Process in Alzheimer Disease: Age Categories From 1 to 100 Years , 2011, Journal of neuropathology and experimental neurology.
[80] Pico Caroni,et al. Selective Neuronal Vulnerability in Neurodegenerative Diseases: from Stressor Thresholds to Degeneration , 2011, Neuron.
[81] Ralph A. Nixon,et al. Autophagy failure in Alzheimer's disease—locating the primary defect , 2011, Neurobiology of Disease.
[82] David Eisenberg,et al. Towards a Pharmacophore for Amyloid , 2011, PLoS biology.
[83] Meaghan Morris,et al. The Many Faces of Tau , 2011, Neuron.
[84] Denise C. Park,et al. Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease , 2011, Alzheimer's & Dementia.
[85] J. Trojanowski,et al. The acetylation of tau inhibits its function and promotes pathological tau aggregation. , 2011, Nature communications.
[86] F. Terro,et al. Post-translational modifications of tau protein: Implications for Alzheimer's disease , 2011, Neurochemistry International.
[87] G. Jackson,et al. Drosophila models of neurodegenerative disease , 2005, NeuroRX.
[88] L. Buée,et al. Nuclear Tau, a Key Player in Neuronal DNA Protection* , 2010, The Journal of Biological Chemistry.
[89] Fei Liu,et al. Tau in Alzheimer disease and related tauopathies. , 2010, Current Alzheimer research.
[90] V. Haroutunian,et al. Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy , 2010, Neuron.
[91] Y. Jho,et al. Monte carlo simulations of tau proteins: effect of phosphorylation. , 2010, Biophysical Journal.
[92] V. Haroutunian,et al. Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy , 2010, Neuron.
[93] D. Wilcock,et al. Loss of tau elicits axonal degeneration in a mouse model of Alzheimer's disease , 2010, Neuroscience.
[94] M. Freeman,et al. Wallerian degeneration, wld(s), and nmnat. , 2010, Annual review of neuroscience.
[95] M. Blackledge,et al. Conformational changes specific for pseudophosphorylation at serine 262 selectively impair binding of tau to microtubules. , 2009, Biochemistry.
[96] Keiji Tanaka,et al. The cellular pathways of neuronal autophagy and their implication in neurodegenerative diseases. , 2009, Biochimica et biophysica acta.
[97] M. Wolfe. Tau Mutations in Neurodegenerative Diseases* , 2009, Journal of Biological Chemistry.
[98] J. Lucas,et al. Tauopathies with parkinsonism: clinical spectrum, neuropathologic basis, biological markers, and treatment options , 2009, European journal of neurology.
[99] I. Grundke‐Iqbal,et al. Mechanisms of tau-induced neurodegeneration , 2009, Acta Neuropathologica.
[100] Michael P. Murphy,et al. How mitochondria produce reactive oxygen species , 2008, The Biochemical journal.
[101] S. Strittmatter,et al. Axon regeneration in the peripheral and central nervous systems. , 2009, Results and problems in cell differentiation.
[102] Mandana Amiri,et al. Mitochondrial biogenesis in the axons of vertebrate peripheral neurons , 2008, Developmental neurobiology.
[103] O. Sporns,et al. Mapping the Structural Core of Human Cerebral Cortex , 2008, PLoS biology.
[104] C. Lyketsos,et al. Mild cognitive impairment: searching for the prodrome of Alzheimer's disease , 2008, World psychiatry : official journal of the World Psychiatric Association.
[105] George Perry,et al. Physiological regulation of tau phosphorylation during hibernation , 2008, Journal of neurochemistry.
[106] Mark A. Smith,et al. Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer’s disease , 2008, International journal of experimental pathology.
[107] I. Grundke‐Iqbal,et al. Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer disease , 2008, FEBS letters.
[108] J. Ávila. Tau kinases and phosphatases , 2007, Journal of cellular and molecular medicine.
[109] J. Trojanowski,et al. Tau-mediated neurodegeneration in Alzheimer's disease and related disorders , 2007, Nature Reviews Neuroscience.
[110] B. Winckler. BDNF Instructs the Kinase LKB1 To Grow an Axon , 2007, Cell.
[111] Tudor A. Fulga,et al. Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo , 2007, Nature Cell Biology.
[112] D. Selkoe,et al. Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide , 2007, Nature Reviews Molecular Cell Biology.
[113] Craig C Garner,et al. Synaptic Protein Dynamics in Hibernation , 2007, The Journal of Neuroscience.
[114] D. Geschwind,et al. Degradation of tau protein by puromycin-sensitive aminopeptidase in vitro. , 2006, Biochemistry.
[115] E. Holzbaur,et al. Axonal transport and neurodegenerative disease. , 2006, Biochimica et biophysica acta.
[116] D. Williams,et al. Tauopathies: classification and clinical update on neurodegenerative diseases associated with microtubule‐associated protein tau , 2006, Internal medicine journal.
[117] H. Braak,et al. Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry , 2006, Acta Neuropathologica.
[118] L. Loeb,et al. The mitochondrial theory of aging and its relationship to reactive oxygen species damage and somatic mtDNA mutations. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[119] Olaf Sporns,et al. The Human Connectome: A Structural Description of the Human Brain , 2005, PLoS Comput. Biol..
[120] E. Masliah,et al. Axonopathy and Transport Deficits Early in the Pathogenesis of Alzheimer's Disease , 2005, Science.
[121] N. Shahani,et al. Tau alteration and neuronal degeneration in tauopathies: mechanisms and models. , 2005, Biochimica et biophysica acta.
[122] Michel Goedert,et al. Mutations causing neurodegenerative tauopathies. , 2005, Biochimica et biophysica acta.
[123] John Q Trojanowski,et al. Transgenic animal models of tauopathies. , 2005, Biochimica et biophysica acta.
[124] J. O’Keefe,et al. Dual phase and rate coding in hippocampal place cells: Theoretical significance and relationship to entorhinal grid cells , 2005, Hippocampus.
[125] F. Liu,et al. Post-translational modifications of tau protein in Alzheimer’s disease , 2005, Journal of Neural Transmission.
[126] Daniel J. Klionsky,et al. Autophagy in Health and Disease: A Double-Edged Sword , 2004, Science.
[127] C. Cotman,et al. Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology. , 2004, The Journal of clinical investigation.
[128] H. Braak,et al. Alzheimer's disease affects limbic nuclei of the thalamus , 2004, Acta Neuropathologica.
[129] H. Braak,et al. Neuropathological stageing of Alzheimer-related changes , 2004, Acta Neuropathologica.
[130] Michel Goedert,et al. Tau filaments from human brain and from in vitro assembly of recombinant protein show cross-β structure , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[131] J. Goldberg. How does an axon grow? , 2003, Genes & development.
[132] H. Braak,et al. Staging of brain pathology related to sporadic Parkinson’s disease , 2003, Neurobiology of Aging.
[133] D. Geschwind,et al. Human Wild-Type Tau Interacts with wingless Pathway Components and Produces Neurofibrillary Pathology in Drosophila , 2002, Neuron.
[134] V. Muñoz,et al. Alpha-helix structure in Alzheimer's disease aggregates of tau-protein. , 2002, Biochemistry.
[135] J. Trojanowski,et al. Neurodegenerative tauopathies. , 2001, Annual review of neuroscience.
[136] R. Crowther,et al. Abnormal tau-containing filaments in neurodegenerative diseases. , 2000, Journal of structural biology.
[137] J. Morris,et al. Tau polymorphisms are not associated with Alzheimer's disease , 2000, Neuroscience Letters.
[138] Barbara Shukitt-Hale,et al. Reversals of Age-Related Declines in Neuronal Signal Transduction, Cognitive, and Motor Behavioral Deficits with Blueberry, Spinach, or Strawberry Dietary Supplementation , 1999, The Journal of Neuroscience.
[139] John X. Morris,et al. Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17. , 1998, Science.
[140] H. Band,et al. Tau interacts with src-family non-receptor tyrosine kinases. , 1998, Journal of cell science.
[141] Ronald C. Petersen,et al. Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17 , 1998, Nature.
[142] N. Cairns,et al. An Assessment of Oxidative Damage to Proteins, Lipids, and DNA in Brain from Patients with Alzheimer's Disease , 1997, Journal of neurochemistry.
[143] B. Van Houten,et al. Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[144] R. Brandt,et al. Interaction of tau with the neural plasma membrane mediated by tau's amino-terminal projection domain , 1995, The Journal of cell biology.
[145] H. Braak,et al. Staging of alzheimer's disease-related neurofibrillary changes , 1995, Neurobiology of Aging.
[146] N. Hirokawa,et al. Projection domains of MAP2 and tau determine spacings between microtubules in dendrites and axons , 1992, Nature.
[147] R. Crowther. Straight and paired helical filaments in Alzheimer disease have a common structural unit. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[148] R. Crowther,et al. Cloning and sequencing of the cDNA encoding an isoform of microtubule‐associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain. , 1989, The EMBO journal.
[149] L. Hood,et al. Purification and structural studies of a major scrapie prion protein , 1984, Cell.
[150] M. Kirschner,et al. Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin. , 1977, Journal of molecular biology.
[151] M. Kirschner,et al. A protein factor essential for microtubule assembly. , 1975, Proceedings of the National Academy of Sciences of the United States of America.
[152] A. Alzheimer. Uber eine eigenartige Erkrankung der Hirnrinde , 1907 .