A Novel Flavonoid Composition Targets Androgen Receptor Signaling and Inhibits Prostate Cancer Growth in Preclinical Models12
暂无分享,去创建一个
P. Nelson | Shumin M. Zhang | O. Kucuk | M. Bartlett | Ilsa M. Coleman | Ilsa M Coleman | Jaeah Kim | K. Mamouni | Daqing Wu | Xin Li | Yang Yang | Yanhua Chen
[1] T. Wilt,et al. Follow‐up of Prostatectomy versus Observation for Early Prostate Cancer , 2017, The New England journal of medicine.
[2] D. Spandidos,et al. Anticancer and apoptosis-inducing effects of quercetin in vitro and in vivo , 2017, Oncology reports.
[3] Xiaoxv Dong,et al. Simultaneous Determination and Pharmacokinetic Study of Quercetin, Luteolin, and Apigenin in Rat Plasma after Oral Administration of Matricaria chamomilla L. Extract by HPLC-UV , 2017, Evidence-based complementary and alternative medicine : eCAM.
[4] David Gillatt,et al. 10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer. , 2017, The New England journal of medicine.
[5] B. Lokeshwar,et al. Bioactive natural products for chemoprevention and treatment of castration-resistant prostate cancer. , 2016, Seminars in cancer biology.
[6] J. Li,et al. Cotargeting HSP90 and Its Client Proteins for Treatment of Prostate Cancer , 2016, Molecular Cancer Therapeutics.
[7] Zuowen Liang,et al. Flavonoids intake and risk of prostate cancer: a meta‐analysis of observational studies , 2016, Andrologia.
[8] S. Gadamsetty,et al. Optimal Dosing for Targeted Therapies in Oncology: Drug Development Cases Leading by Example , 2015, Clinical Cancer Research.
[9] Xin-yang Wang,et al. Kaempferol suppresses bladder cancer tumor growth by inhibiting cell proliferation and inducing apoptosis , 2015, Molecular carcinogenesis.
[10] L. Howells,et al. Cancer chemoprevention: Evidence of a nonlinear dose response for the protective effects of resveratrol in humans and mice , 2015, Science Translational Medicine.
[11] J. Dwyer,et al. Recommendations on reporting requirements for flavonoids in research. , 2015, The American journal of clinical nutrition.
[12] D. Bates,et al. Regulation of vascular endothelial growth factor in prostate cancer. , 2015, Endocrine-related cancer.
[13] S. Mudan,et al. The Concept of Hormesis in Cancer Therapy – Is Less More? , 2015, Cureus.
[14] Ziyan Wang,et al. Emerging roles of ATF3 in the suppression of prostate cancer , 2015, Molecular & cellular oncology.
[15] A. Murakami. Dose-dependent functionality and toxicity of green tea polyphenols in experimental rodents. , 2014, Archives of biochemistry and biophysics.
[16] B. Bao,et al. Recent progress on nutraceutical research in prostate cancer , 2014, Cancer and Metastasis Reviews.
[17] K. Sak. Cytotoxicity of dietary flavonoids on different human cancer types , 2014, Pharmacognosy reviews.
[18] R. Thomas,et al. A double-blind, placebo-controlled randomised trial evaluating the effect of a polyphenol-rich whole food supplement on PSA progression in men with prostate cancer—the UK NCRN Pomi-T study , 2014, Prostate Cancer and Prostatic Disease.
[19] Wei Zhang,et al. The von hippel-lindau protein suppresses androgen receptor activity. , 2014, Molecular endocrinology.
[20] Monique J. Roobol,et al. Defining the threshold for significant versus insignificant prostate cancer , 2013, Nature Reviews Urology.
[21] Jorge Sainz,et al. Consumption of the Dietary Flavonoids Quercetin, Luteolin and Kaempferol and Overall Risk of Cancer - A Review and Meta-Analysis of the Epidemiological Data , 2013 .
[22] A. Rodriguez-Mateos,et al. Dietary (poly)phenolics in human health: structures, bioavailability, and evidence of protective effects against chronic diseases. , 2013, Antioxidants & redox signaling.
[23] L. Luo,et al. Luteolin Induces Carcinoma Cell Apoptosis through Binding Hsp90 to Suppress Constitutive Activation of STAT3 , 2012, PloS one.
[24] M. Gleave,et al. Slug, a unique androgen-regulated transcription factor, coordinates androgen receptor to facilitate castration resistance in prostate cancer. , 2012, Molecular endocrinology.
[25] R. Walther,et al. Effect of the heat shock protein HSP27 on androgen receptor expression and function in prostate cancer cells , 2012, World Journal of Urology.
[26] G. Yen,et al. Flavonoids, a ubiquitous dietary phenolic subclass, exert extensive in vitro anti-invasive and in vivo anti-metastatic activities , 2012, Cancer and Metastasis Reviews.
[27] Ming Yan,et al. Oral administration of quercetin inhibits bone loss in rat model of diabetic osteopenia. , 2011, European journal of pharmacology.
[28] Y. Ogata,et al. Kaempferol stimulates bone sialoprotein gene transcription and new bone formation , 2010, Journal of cellular biochemistry.
[29] Zhiguo Yu,et al. Pharmacokinetics of luteolin and tetra-acetyl-luteolin assayed by HPLC in rats after oral administration. , 2010, Biomedical chromatography : BMC.
[30] A. Scorilas,et al. KLK5 gene expression is severely upregulated in androgen-independent prostate cancer cells after treatment with the chemotherapeutic agents docetaxel and mitoxantrone , 2010, Biological chemistry.
[31] A. Kong,et al. Metabolism, oral bioavailability and pharmacokinetics of chemopreventive kaempferol in rats. , 2009, Biopharmaceutics & drug disposition.
[32] Haitao Luo,et al. Kaempferol Inhibits Angiogenesis and VEGF Expression Through Both HIF Dependent and Independent Pathways in Human Ovarian Cancer Cells , 2009, Nutrition and cancer.
[33] J. Crowley,et al. Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). , 2009, JAMA.
[34] Haitao Luo,et al. Inhibition of Cell Growth and VEGF Expression in Ovarian Cancer Cells by Flavonoids , 2008, Nutrition and cancer.
[35] J. Stewart,et al. BKM1740, an Acyl-Tyrosine Bisphosphonate Amide Derivative, Inhibits the Bone Metastatic Growth of Human Prostate Cancer Cells by Inducing Apoptosis , 2008, Clinical Cancer Research.
[36] D. Lee,et al. Quercetin suppresses hypoxia‐induced accumulation of hypoxia‐inducible factor‐1α (HIF‐1α) through inhibiting protein synthesis , 2008, Journal of cellular biochemistry.
[37] S. Eschrich,et al. Persistent Activation of Stat3 Signaling Induces Survivin Gene Expression and Confers Resistance to Apoptosis in Human Breast Cancer Cells , 2006, Clinical Cancer Research.
[38] M. Neuhouser. Review: Dietary Flavonoids and Cancer Risk: Evidence From Human Population Studies , 2004, Nutrition and cancer.
[39] H. Fuse,et al. Molecular interactions between STAT3 and protein inhibitor of activated STAT3, and androgen receptor. , 2003, Biochemical and biophysical research communications.
[40] J. Downward,et al. The ubiquitin-proteasome pathway regulates survivin degradation in a cell cycle-dependent manner. , 2000, Journal of cell science.
[41] J W Moul,et al. A novel androgen-regulated gene, PMEPA1, located on chromosome 20q13 exhibits high level expression in prostate. , 2000, Genomics.
[42] P. Hollman,et al. Health effects and bioavailability of dietary flavonols. , 1999, Free radical research.
[43] L. Hood,et al. Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2. , 1999, Cancer research.
[44] R. Hansen,et al. Quercetin inhibits heat shock protein induction but not heat shock factor DNA-binding in human breast carcinoma cells. , 1997, Biochemical and biophysical research communications.
[45] C. Bieberich,et al. Prostate-specific and Androgen-dependent Expression of a Novel Homeobox Gene* , 1996, The Journal of Biological Chemistry.
[46] D. Tindall,et al. Hormonal regulation of prostate-specific antigen messenger RNA in human prostatic adenocarcinoma cell line LNCaP. , 1991, Cancer research.
[47] A. Jemal,et al. Cancer statistics, 2018 , 2018, CA: a cancer journal for clinicians.
[48] D. Szostak-Węgierek,et al. Flavonoids--food sources and health benefits. , 2014, Roczniki Panstwowego Zakladu Higieny.
[49] J. Hong,et al. The effects of luteolin on osteoclast differentiation, function in vitro and ovariectomy-induced bone loss. , 2011, The Journal of nutritional biochemistry.
[50] Jen-kun Lin,et al. Downregulation of androgen receptor expression by luteolin causes inhibition of cell proliferation and induction of apoptosis in human prostate cancer cells and xenografts , 2008, The Prostate.
[51] Gary Williamson,et al. Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies. , 2005, The American journal of clinical nutrition.
[52] A. Scorilas,et al. Quantitative Analysis of Human Kallikrein 5 (klk5) Expression in Prostate Needle Biopsies: an Independent Cancer Biomarker , 2022 .