What are microarrays teaching us about sleep?

[1]  A. Pack,et al.  Molecular signatures of obstructive sleep apnea in adults: a review and perspective. , 2009, Sleep.

[2]  Marcel H. Schulz,et al.  A Global View of Gene Activity and Alternative Splicing by Deep Sequencing of the Human Transcriptome , 2008, Science.

[3]  J. Siegel,et al.  Unearthing the Phylogenetic Roots of Sleep , 2008, Current Biology.

[4]  G. Tononi,et al.  Is Sleep Essential? , 2008, PLoS biology.

[5]  A. Sehgal,et al.  Identification of SLEEPLESS, a Sleep-Promoting Factor , 2008, Science.

[6]  E. Youngsteadt.  Simple Sleepers , 2008, Science.

[7]  David M. Raizen,et al.  Conservation of sleep: insights from non-mammalian model systems , 2008, Trends in Neurosciences.

[8]  Daniel Bushey,et al.  Sleep and Wakefulness inDrosophila melanogaster , 2008, Annals of the New York Academy of Sciences.

[9]  Chiara Cirelli,et al.  Molecular correlates of sleep and wakefulness in the brain of the white‐crowned sparrow , 2008, Journal of neurochemistry.

[10]  E. Mignot.  Why We Sleep: The Temporal Organization of Recovery , 2008, PLoS biology.

[11]  A. Sehgal,et al.  A genetic screen for sleep and circadian mutants reveals mechanisms underlying regulation of sleep in Drosophila. , 2008, Sleep.

[12]  M. D. Bono,et al.  Dispatches Sleep : Dozy Worms and Sleepy Flies , 2022 .

[13]  A. Pack,et al.  Analysis of the QTL for sleep homeostasis in mice: Homer1a is a likely candidate. , 2008, Physiological genomics.

[14]  David M. Raizen,et al.  Lethargus is a Caenorhabditis elegans sleep-like state , 2008, Nature.

[15]  G. Tononi,et al.  Molecular and electrophysiological evidence for net synaptic potentiation in wake and depression in sleep , 2008, Nature Neuroscience.

[16]  S. Pradervand,et al.  Homer1a is a core brain molecular correlate of sleep loss , 2007, Proceedings of the National Academy of Sciences.

[17]  Shane T. Jensen,et al.  Macromolecule biosynthesis: a key function of sleep. , 2007, Physiological genomics.

[18]  Emmanuel Mignot,et al.  Characterization of Sleep in Zebrafish and Insomnia in Hypocretin Receptor Mutants , 2007, PLoS biology.

[19]  C. Liew,et al.  The peripheral-blood transcriptome: new insights into disease and risk assessment. , 2007, Trends in molecular medicine.

[20]  Paul W Sternberg,et al.  Epidermal growth factor signaling induces behavioral quiescence in Caenorhabditis elegans , 2007, Nature Neuroscience.

[21]  G. O'Connor,et al.  Genome-wide association of sleep and circadian phenotypes , 2007, BMC Medical Genetics.

[22]  Ralph J Greenspan,et al.  Activation of EGFR and ERK by rhomboid signaling regulates the consolidation and maintenance of sleep in Drosophila , 2007, Nature Neuroscience.

[23]  B. Dickson,et al.  A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila , 2007, Nature.

[24]  E. van Cauter,et al.  The metabolic consequences of sleep deprivation. , 2007, Sleep medicine reviews.

[25]  V. Somers,et al.  Microarray studies of genomic oxidative stress and cell cycle responses in obstructive sleep apnea. , 2007, Antioxidants & redox signaling.

[26]  A. Pack,et al.  A role for the molecular chaperone protein BiP/GRP78 in Drosophila sleep homeostasis. , 2007, Sleep.

[27]  C. Peyron,et al.  Gene expression in the rat brain during sleep deprivation and recovery sleep: an Affymetrix GeneChip® study , 2006, Neuroscience.

[28]  S. Duntley,et al.  Identification of a biomarker for sleep drive in flies and humans , 2006, Proceedings of the National Academy of Sciences.

[29]  Alexander F. Schier,et al.  Hypocretin/Orexin Overexpression Induces An Insomnia-Like Phenotype in Zebrafish , 2006, The Journal of Neuroscience.

[30]  Keith R Shockley,et al.  Multiple mechanisms limit the duration of wakefulness in Drosophila brain. , 2006, Physiological genomics.

[31]  M. Irwin,et al.  Sleep deprivation and activation of morning levels of cellular and genomic markers of inflammation. , 2006, Archives of internal medicine.

[32]  G. Tononi,et al.  Changes in brain gene expression after long‐term sleep deprivation , 2006, Journal of neurochemistry.

[33]  S. Nelson,et al.  The problem of neuronal cell types: a physiological genomics approach , 2006, Trends in Neurosciences.

[34]  A. Pack,et al.  A Novel Gain-of-Function Mutant of the Cyclic GMP-Dependent Protein Kinase egl-4 Affects Multiple Physiological Processes in Caenorhabditis elegans , 2006, Genetics.

[35]  André Schrattenholz,et al.  NMDA receptors are not alone: dynamic regulation of NMDA receptor structure and function by neuregulins and transient cholesterol-rich membrane domains leads to disease-specific nuances of glutamate-signalling. , 2006, Current topics in medicinal chemistry.

[36]  W. McNicholas,et al.  Obstructive sleep apnoea syndrome: Translating science to clinical practice , 2006, Respirology.

[37]  G. Tononi,et al.  Sleep function and synaptic homeostasis. , 2006, Sleep medicine reviews.

[38]  C. Saper,et al.  Homeostatic, circadian, and emotional regulation of sleep , 2005, The Journal of comparative neurology.

[39]  J. Hobson.  Sleep is of the brain, by the brain and for the brain , 2005, Nature.

[40]  R. Stickgold.  Sleep-dependent memory consolidation , 2005, Nature.

[41]  Drew Dawson,et al.  Managing fatigue: it's about sleep. , 2005, Sleep medicine reviews.

[42]  S. Oehler,et al.  Minos as a Genetic and Genomic Tool in Drosophila melanogaster , 2005, Genetics.

[43]  Giulio Tononi,et al.  Sleep and wakefulness modulate gene expression in Drosophila , 2005, Journal of neurochemistry.

[44]  Joshua M Hare,et al.  Molecular signature analysis: using the myocardial transcriptome as a biomarker in cardiovascular disease. , 2005, Trends in cardiovascular medicine.

[45]  Giulio Tononi,et al.  Reduced sleep in Drosophila Shaker mutants , 2005, Nature.

[46]  D. Dinges,et al.  Individual differences in adult human sleep and wakefulness: Leitmotif for a research agenda. , 2005, Sleep.

[47]  A. Pack,et al.  Sleep deprivation induces the unfolded protein response in mouse cerebral cortex , 2005, Journal of neurochemistry.

[48]  Vladyslav V Vyazovskiy,et al.  Regional pattern of metabolic activation is reflected in the sleep EEG after sleep deprivation combined with unilateral whisker stimulation in mice , 2004, The European journal of neuroscience.

[49]  M. Butchbach,et al.  Association of Excitatory Amino Acid Transporters, Especially EAAT2, with Cholesterol-rich Lipid Raft Microdomains , 2004, Journal of Biological Chemistry.

[50]  G. Tononi,et al.  Locus Ceruleus Control of State-Dependent Gene Expression , 2004, The Journal of Neuroscience.

[51]  Feng Chen,et al.  A complementary transposon tool kit for Drosophila melanogaster using P and piggyBac , 2004, Nature Genetics.

[52]  Ronald L. Davis,et al.  Spatiotemporal Gene Expression Targeting with the TARGET and Gene-Switch Systems in Drosophila , 2004, Science's STKE.

[53]  G. Tononi,et al.  Extensive and Divergent Effects of Sleep and Wakefulness on Brain Gene Expression , 2004, Neuron.

[54]  G. Tononi,et al.  Sleep and synaptic homeostasis: a hypothesis , 2003, Brain Research Bulletin.

[55]  P. Sternberg,et al.  The draft genome sequence of the nematode Caenorhabditis briggsae, a companion to C. elegans , 2003, Genome Biology.

[56]  F. Wieland,et al.  Glutamate-binding affinity of Drosophila metabotropic glutamate receptor is modulated by association with lipid rafts , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[57]  A. Pack,et al.  Genetic evidence for a role of CREB in sustained cortical arousal. , 2003, Journal of neurophysiology.

[58]  A. Pack,et al.  Functional genomics of sleep , 2003, Respiratory Physiology & Neurobiology.

[59]  M. Tafti,et al.  Genetics of sleep and sleep disorders. , 2003, Frontiers in bioscience : a journal and virtual library.

[60]  Heike Hering,et al.  Lipid Rafts in the Maintenance of Synapses, Dendritic Spines, and Surface AMPA Receptor Stability , 2003, The Journal of Neuroscience.

[61]  D. Dinges,et al.  The cumulative cost of additional wakefulness: dose-response effects on neurobehavioral functions and sleep physiology from chronic sleep restriction and total sleep deprivation. , 2003, Sleep.

[62]  Atul Malhotra,et al.  A prospective study of sleep duration and coronary heart disease in women. , 2003, Archives of internal medicine.

[63]  R. Kaufman,et al.  The mammalian unfolded protein response. , 2003, Annual review of biochemistry.

[64]  H. Heller,et al.  Differential increase in the expression of heat shock protein family members during sleep deprivation and during sleep , 2003, Neuroscience.

[65]  R. Kaufman.  Orchestrating the unfolded protein response in health and disease. , 2002, The Journal of clinical investigation.

[66]  John D. Storey.  A direct approach to false discovery rates , 2002 .

[67]  J. Hobson,et al.  The Neurobiology of Sleep: Genetics, cellular physiology and subcortical networks , 2002, Nature Reviews Neuroscience.

[68]  G. Tononi,et al.  Stress response genes protect against lethal effects of sleep deprivation in Drosophila , 2002, Nature.

[69]  L. Hendershot,et al.  The mammalian endoplasmic reticulum as a sensor for cellular stress , 2002, Cell stress & chaperones.

[70]  M. Tafti,et al.  Invited review: genetic dissection of sleep. , 2002, Journal of applied physiology.

[71]  P. Worley,et al.  Synaptic Activity-Induced Conversion of Intronic to Exonic Sequence in Homer 1 Immediate Early Gene Expression , 2002, The Journal of Neuroscience.

[72]  Thomas E. Scammell,et al.  The sleep switch: hypothalamic control of sleep and wakefulness , 2001, Trends in Neurosciences.

[73]  A. Sehgal,et al.  A non-circadian role for cAMP signaling and CREB activity in Drosophila rest homeostasis , 2001, Nature Neuroscience.

[74]  I. Zhdanova,et al.  Melatonin promotes sleep-like state in zebrafish 1 1 Published on the World Wide Web on 6 April 2001. , 2001, Brain Research.

[75]  John Quackenbush,et al.  Computational genetics: Computational analysis of microarray data , 2001, Nature Reviews Genetics.

[76]  D Chollet,et al.  The Homeostatic Regulation of Sleep Need Is under Genetic Control , 2001, The Journal of Neuroscience.

[77]  M. Stryker,et al.  Sleep Enhances Plasticity in the Developing Visual Cortex , 2001, Neuron.

[78]  J. V. Moran,et al.  Initial sequencing and analysis of the human genome. , 2001, Nature.

[79]  G. Churchill,et al.  Statistical design and the analysis of gene expression microarray data. , 2001, Genetical research.

[80]  G. Tononi,et al.  Gene expression in the brain across the sleep–waking cycle 1 1 Published on the World Wide Web on 30 October 2000. , 2000, Brain Research.

[81]  V. Vyazovskiy,et al.  Fast track:Unilateral vibrissae stimulation during waking induces interhemispheric EEG asymmetry during subsequent sleep in the rat , 2000, Journal of sleep research.

[82]  Kai Simons,et al.  Lipid rafts and signal transduction , 2000, Nature Reviews Molecular Cell Biology.

[83]  Anne Bertolotti,et al.  Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response , 2000, Nature Cell Biology.

[84]  Stephen M. Mount,et al.  The genome sequence of Drosophila melanogaster. , 2000, Science.

[85]  G. Tononi,et al.  Correlates of sleep and waking in Drosophila melanogaster. , 2000, Science.

[86]  Allan I Pack,et al.  Rest in Drosophila Is a Sleep-like State , 2000, Neuron.

[87]  G. Rubin,et al.  The Berkeley Drosophila Genome Project gene disruption project: Single P-element insertions mutating 25% of vital Drosophila genes. , 1999, Genetics.

[88]  A. Malafosse,et al.  Genetic determinants of sleep regulation in inbred mice. , 1999, Sleep.

[89]  A. Malafosse,et al.  Genetic variation in EEG activity during sleep in inbred mice. , 1998, American journal of physiology. Regulatory, integrative and comparative physiology.

[90]  G. Tononi,et al.  Differences in gene expression between sleep and waking as revealed by mRNA differential display. , 1998, Brain research. Molecular brain research.

[91]  M. Mishkin,et al.  Positive Correlations Between Cerebral Protein Synthesis Rates and Deep Sleep in Macaca mulatta , 1997, The European journal of neuroscience.

[92]  Hans P. A. Van Dongen,et al.  Morning-type and evening-type individuals differ in the phase position of their endogenous circadian oscillator , 1996, Neuroscience Letters.

[93]  A. Pardee,et al.  Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. , 1992, Science.

[94]  A. Dorner,et al.  Overexpression of GRP78 mitigates stress induction of glucose regulated proteins and blocks secretion of selective proteins in Chinese hamster ovary cells. , 1992, The EMBO journal.

[95]  J. Mallet,et al.  Molecular Cloning of Forebrain mRNAs which are Modulated by Sleep Deprivation , 1990, The European journal of neuroscience.

[96]  P. Ramm,et al.  Rates of cerebral protein synthesis are linked to slow wave sleep in the rat , 1990, Physiology & Behavior.

[97]  L. Kheirandish-Gozal,et al.  Genome-wide gene expression profiling in children with non-obese obstructive sleep apnea. , 2009, Sleep medicine.

[98]  Sunil Kumar,et al.  Salubrinal, an inhibitor of protein synthesis, promotes deep slow wave sleep. , 2009, American journal of physiology. Regulatory, integrative and comparative physiology.

[99]  Allan I Pack,et al.  Advances in sleep-disordered breathing. , 2006, American journal of respiratory and critical care medicine.

[100]  H. Colten,et al.  Sleep Disorders and Sleep Deprivation , 2006 .

[101]  J. Dorrian,et al.  Fatigue and the criminal law. , 2005, Industrial health.