Association between mitochondrial DNA variations and Alzheimer's disease in the ADNI cohort

[1]  Michael Weiner,et al.  Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort , 2010, NeuroImage.

[2]  Robert W. Taylor,et al.  Mitochondrial DNA mutations and human disease. , 2010, Biochimica et biophysica acta.

[3]  R. Gold,et al.  Mitochondrial haplogroup H correlates with ATP levels and age at onset in Huntington disease , 2010, Journal of Molecular Medicine.

[4]  D. Wallace,et al.  Mitochondrial energetics and therapeutics. , 2010, Annual review of pathology.

[5]  A D Roses,et al.  A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease , 2009, The Pharmacogenomics Journal.

[6]  Riitta Parkkola,et al.  Cerebral oxygen and glucose metabolism in patients with mitochondrial m.3243A>G mutation. , 2009, Brain : a journal of neurology.

[7]  Andrew J. Saykin,et al.  Hippocampal Atrophy as a Quantitative Trait in a Genome-Wide Association Study Identifying Novel Susceptibility Genes for Alzheimer's Disease , 2009, PloS one.

[8]  P. Reddy,et al.  Amyloid beta, mitochondrial structural and functional dynamics in Alzheimer's disease , 2009, Experimental Neurology.

[9]  George Perry,et al.  Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease , 2009, The Journal of Neuroscience.

[10]  M. Beal Faculty Opinions recommendation of S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury. , 2009 .

[11]  J. Quevedo,et al.  Mitochondrial Dysfunction and Psychiatric Disorders , 2009, Neurochemical Research.

[12]  A. Godzik,et al.  S-Nitrosylation of Drp1 Mediates β-Amyloid-Related Mitochondrial Fission and Neuronal Injury , 2009, Science.

[13]  Sarah J. Spence,et al.  Neurometabolic disorders and dysfunction in autism spectrum disorders , 2009, Current neurology and neuroscience reports.

[14]  Manfred Kayser,et al.  Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation , 2009, Human mutation.

[15]  J. Goedert,et al.  Mitochondrial DNA haplogroups influence AIDS progression , 2008, AIDS.

[16]  D. Wallace Mitochondria as Chi , 2008, Genetics.

[17]  Winnie S. Liang,et al.  Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons , 2008, Proceedings of the National Academy of Sciences.

[18]  D. Cestari,et al.  The Genetics of Leber Hereditary Optic Neuropathy—Prototype of an Inherited Optic Neuropathy with Mitochondrial Dysfunction , 2008, Seminars in ophthalmology.

[19]  Xiongwei Zhu,et al.  Insights into amyloid-β-induced mitochondrial dysfunction in Alzheimer disease , 2007 .

[20]  Manuel A. R. Ferreira,et al.  PLINK: a tool set for whole-genome association and population-based linkage analyses. , 2007, American journal of human genetics.

[21]  M. Mamelak Alzheimer’ s disease, oxidative stress and gammahydroxybutyrate , 2007, Neurobiology of Aging.

[22]  F. Coppedè,et al.  A Ser326Cys polymorphism in the DNA repair gene hOGG1 is not associated with sporadic Alzheimer's disease , 2007, Neuroscience Letters.

[23]  M. Beal,et al.  Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases , 2006, Nature.

[24]  D. Galati,et al.  Accumulation of Amyloid Precursor Protein in the Mitochondrial Import Channels of Human Alzheimer’s Disease Brain Is Associated with Mitochondrial Dysfunction , 2006, The Journal of Neuroscience.

[25]  David Goldman,et al.  Using ancestry-informative markers to define populations and detect population stratification , 2006, Journal of psychopharmacology.

[26]  D. Wallace,et al.  Differences of sperm motility in mitochondrial DNA haplogroup U sublineages. , 2006, Gene.

[27]  Douglass M. Turnbull,et al.  Does the mitochondrial genome play a role in the etiology of Alzheimer’s disease? , 2006, Human Genetics.

[28]  D. Wallace The mitochondrial genome in human adaptive radiation and disease: on the road to therapeutics and performance enhancement. , 2005, Gene.

[29]  C. Masters,et al.  Copper-Dependent Inhibition of Human Cytochrome c Oxidase by a Dimeric Conformer of Amyloid-β1-42 , 2005, The Journal of Neuroscience.

[30]  M. Beal,et al.  Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[31]  J. Gilbert,et al.  Analysis of European mitochondrial haplogroups with Alzheimer disease risk , 2004, Neuroscience Letters.

[32]  G. Alexander,et al.  Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[33]  M. Jamon,et al.  Mitochondrial DNA modifies cognition in interaction with the nuclear genome and age in mice , 2003, Nature Genetics.

[34]  U. Gyllensten,et al.  Analysis of the complete human mtDNA genome: methodology and inferences for human evolution. , 2001, The Journal of heredity.

[35]  M. Lehtonen,et al.  Phylogenetic network for European mtDNA. , 2001, American journal of human genetics.

[36]  I. McKeith,et al.  Mitochondrial DNA haplogroups and susceptibility to AD and dementia with Lewy bodies , 2000, Neurology.

[37]  F J McMahon,et al.  Mitochondrial DNA sequence diversity in bipolar affective disorder. , 2000, The American journal of psychiatry.

[38]  M. Belouchi,et al.  Phylogenetic analysis of the mitochondrial genome indicates significant differences between patients with Alzheimer disease and controls in a French-Canadian founder population. , 1999, American journal of medical genetics.

[39]  B. Sykes,et al.  Phylogeography of mitochondrial DNA in western Europe , 1998, Annals of human genetics.

[40]  N Howell,et al.  Mutations in mitochondrial cytochrome c oxidase genes segregate with late-onset Alzheimer disease. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[41]  A. Torroni,et al.  Classification of European mtDNAs from an analysis of three European populations. , 1996, Genetics.

[42]  H. Bandelt,et al.  Paleolithic and neolithic lineages in the European mitochondrial gene pool. , 1996, American journal of human genetics.

[43]  H. Kinoshita,et al.  A case of obstructive icterus caused by incarceration of a pancreatic stone in the common channel of the pancreatobiliary ducts. , 1996, The Kurume medical journal.

[44]  D. Wallace,et al.  Mitochondrial DNA sequence analysis of four Alzheimer's and Parkinson's disease patients. , 1996, American journal of medical genetics.

[45]  B. Crain,et al.  Mitochondrial DNA variants observed in Alzheimer disease and Parkinson disease patients. , 1993, Genomics.

[46]  D. Wallace,et al.  Leber's hereditary optic neuropathy: a model for mitochondrial neurodegenerative diseases , 1992, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[47]  H. Brody,et al.  The aging brain , 1992, Acta neurologica Scandinavica. Supplementum.

[48]  D. Wallace,et al.  Energetics, epigenetics, mitochondrial genetics. , 2010, Mitochondrion.

[49]  B. Vissel,et al.  Alzheimer's disease selective vulnerability and modeling in transgenic mice. , 2009, Journal of Alzheimer's disease : JAD.

[50]  Xiongwei Zhu,et al.  Insights into amyloid-beta-induced mitochondrial dysfunction in Alzheimer disease. , 2007, Free radical biology & medicine.

[51]  Gabriele Siciliano,et al.  Mitochondrial dysfunction, oxidative stress and neurodegeneration. , 2006, Journal of Alzheimer's disease : JAD.

[52]  N. Schork,et al.  The future of genetic case-control studies. , 2001, Advances in genetics.

[53]  E. Fosslien Mitochondrial medicine--molecular pathology of defective oxidative phosphorylation. , 2001, Annals of clinical and laboratory science.

[54]  G. Lubec Protein Expression in Down Syndrome Brain , 2001, Springer Vienna.

[55]  S. Melov,et al.  Mitochondrial biology, degenerative diseases and aging , 1998, BioFactors.

[56]  B. Bainbridge,et al.  Genetics , 1981, Experientia.