论文信息 - Numerical modeling and theoretical analysis of femtosecond laser tweezers

Numerical modeling and theoretical analysis of femtosecond laser tweezers

Abstract Optical trapping (also called optical tweezers) is a widespread technique, with a large number of applications in biology and other fields. Taking femtosecond laser pulses as a sampling of CW light, we theoretically demonstrate the feasibility of femtosecond laser tweezers and present the formulae of the induced forces which femtosecond laser pulses exert on micrometer-sized spheres. We also demonstrate the stability condition for femtosecond laser tweezers. As an example, we present the numerical results for a sphere with a radius of 10 mm .

[1] J G Fujimoto,et al. Generation of 5-fs pulses and octave-spanning spectra directly from a Ti:sapphire laser. , 2001, Optics letters.

[2] T. Lindmo,et al. Calculation of the trapping force in a strongly focused laser beam , 1992 .

[3] Karsten König,et al. Cell biology: Targeted transfection by femtosecond laser , 2002, Nature.

[4] G. Sonek,et al. Evidence for localized cell heating induced by infrared optical tweezers. , 1995, Biophysical journal.

[5] B G de Grooth,et al. Experimental and theoretical investigations on the validity of the geometrical optics model for calculating the stability of optical traps. , 1991, Cytometry.

[6] Buer,et al. Insertion of microscopic objects through plant cell walls using laser microsurgery , 1998, Biotechnology and bioengineering.

[7] G. Mourou,et al. Photodisruption in the human cornea as a function of laser pulse width. , 1997, Journal of refractive surgery.

[8] A. Ashkin,et al. Applications of laser radiation pressure. , 1980, Science.

[9] L A Dubridge. Science and National Security. , 1954, Science.

[10] M W Berns,et al. Physiological monitoring of optically trapped cells: assessing the effects of confinement by 1064-nm laser tweezers using microfluorometry. , 1996, Biophysical journal.