Leukemia Cancer Detection Using Image Analytics : (Comparative Study)

Leukemia is a cancer of white blood cells (WBC). It can be fatal if not detected early. Microscopic images are studied by hematologists for detecting cancer. This manual detection becomes very tedious and time-consuming process. Leukemia if detected in earlier stages, can be cured. But traditional process causes late detection of cancerous cells. Hence in order to minimize the death caused due to late detection, an automated system can be used. This paper proposes an automated system which uses image analytics. Based on image analytics and classification algorithms performed on cell image samples of patients, the proposed system will give correct output. The dataset for experimentation is obtained from TCIA (The Cancer Imaging Archive) repository. The dataset is already pre-processed. An open source tool, "Orange-Data Mining" is used for predictions. In this comparative study, it was found that K-means clustering performs well for segmentation phase and also Neural Networks gives better results for classification phase. We have achieved AUC (area under curve) 0.865, Calculation accuracy (0.838), precision (0.835) and F1(0.836) for neural networks.

[1]  Bhagyashri G. Patil Cancer Cells Detection Using Digital Image Processing Methods , 2014 .

[2]  Ashutosh Mishra,et al.  Automated Leukaemia Detection Using Microscopic Images , 2015 .

[3]  Ritu Gupta,et al.  GCTI-SN: Geometry-inspired chemical and tissue invariant stain normalization of microscopic medical images , 2020, Medical Image Anal..

[4]  Rahul Duggal,et al.  Stain Color Normalization and Segmentation of Plasma Cells in Microscopic Images as a Prelude to Development of Computer Assisted Automated Disease Diagnostic Tool in Multiple Myeloma , 2017 .

[5]  Preeti Jagadev,et al.  Detection of leukemia and its types using image processing and machine learning , 2017, 2017 International Conference on Trends in Electronics and Informatics (ICEI).

[6]  Edgar J. Lobaton,et al.  A comparative study of image classification algorithms for Foraminifera identification , 2017, 2017 IEEE Symposium Series on Computational Intelligence (SSCI).

[7]  Yan Hao,et al.  Image Segmentation Algorithms Overview , 2017, ArXiv.

[8]  Lalit Mohan Saini,et al.  Robust technique for the detection of Acute Lymphoblastic Leukemia , 2015, 2015 IEEE Power, Communication and Information Technology Conference (PCITC).

[9]  Anubha Gupta,et al.  Overlapping cell nuclei segmentation in microscopic images using deep belief networks , 2016, ICVGIP '16.

[10]  H. S. Bhadauria,et al.  Comparative analysis of segmentation algorithms for leukocyte extraction in the acute Lymphoblastic Leukemia images , 2014, 2014 International Conference on Parallel, Distributed and Grid Computing.

[11]  Anubha Gupta,et al.  SD-Layer: Stain Deconvolutional Layer for CNNs in Medical Microscopic Imaging , 2017, MICCAI.

[12]  Vijay Kumar,et al.  Importance of Statistical Measures in Digital Image Processing , 2012 .

[13]  Ashwini Rejintal,et al.  Image processing based leukemia cancer cell detection , 2016, 2016 IEEE International Conference on Recent Trends in Electronics, Information & Communication Technology (RTEICT).

[14]  S. Hariprasath,et al.  Diagnosis of Leukemia and its types Using Digital Image Processing Techniques , 2018, 2018 3rd International Conference on Communication and Electronics Systems (ICCES).