Oxidation of the Methyl Group at the Aromatic Nucleus with Molecular Oxygen in the Presence of N-Bromosuccinimide under Photoirradiation
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A methyl group at the aromatic nucleus can be oxidized to the corresponding carboxylic acid directly in the presence of N-bromosuccinimide (NBS) under photoirradiation. By considering both the promoting effect of oxygen and a catalytic amount of NBS, aerobic oxidation via hydroperoxide, which is thought to be generated by abstraction of a hydrogen with a bromo radical from NBS, proceeded.