Cancer-associated fibroblast senescence and its relation with tumour-infiltrating lymphocytes and PD-L1 expressions in intrahepatic cholangiocarcinoma

[1]  H. Kamachi,et al.  Prognostic impact of CD8+ T cell distribution and its association with the HLA class I expression in intrahepatic cholangiocarcinoma , 2020, Surgery Today.

[2]  H. Baba,et al.  Cellular Senescence, Represented by Expression of Caveolin-1, in Cancer-Associated Fibroblasts Promotes Tumor Invasion in Pancreatic Cancer , 2019, Annals of Surgical Oncology.

[3]  Nicolas Patel,et al.  Incidence of Cholangiocarcinoma in the USA from 2001 to 2015: A US Cancer Statistics Analysis of 50 States , 2019, Cureus.

[4]  T. Fujiwara,et al.  Cancer-Associated Fibroblasts Affect Intratumoral CD8+ and FoxP3+ T Cells Via IL6 in the Tumor Microenvironment , 2018, Clinical Cancer Research.

[5]  Q. Xia,et al.  Current status of liver transplantation for cholangiocarcinoma , 2018, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

[6]  G. Sapisochin,et al.  Current status of liver transplantation for cholangiocarcinoma , 2018, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

[7]  J. Herman,et al.  Caveolin-1 promotes the tumor suppressor properties of oncogene-induced cellular senescence , 2017, The Journal of Biological Chemistry.

[8]  H. Baba,et al.  PD-L1 Expression, Tumor-infiltrating Lymphocytes, and Clinical Outcome in Patients With Surgically Resected Esophageal Cancer , 2017, Annals of surgery.

[9]  T. Ishiko,et al.  Tumour-infiltrating inflammatory and immune cells in patients with extrahepatic cholangiocarcinoma , 2017, British Journal of Cancer.

[10]  Elijah Dixon,et al.  Epidemiology and risk factors: intrahepatic cholangiocarcinoma. , 2017, Hepatobiliary surgery and nutrition.

[11]  R. Kalluri.  The biology and function of fibroblasts in cancer , 2016, Nature Reviews Cancer.

[12]  Yuli Lin,et al.  FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3-CCL2 Signaling. , 2016, Cancer research.

[13]  Antoni Ribas,et al.  Classifying Cancers Based on T-cell Infiltration and PD-L1. , 2015, Cancer research.

[14]  Jinming Yu,et al.  Tumor infiltrating lymphocytes (TILs) before and after neoadjuvant chemoradiotherapy and its clinical utility for rectal cancer. , 2015, American journal of cancer research.

[15]  Xuchao Xue,et al.  Caveolin-1 is a Modulator of Fibroblast Activation and a Potential Biomarker for Gastric Cancer , 2015, International journal of biological sciences.

[16]  T. Nielsen,et al.  The evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer: recommendations by an International TILs Working Group 2014. , 2015, Annals of oncology : official journal of the European Society for Medical Oncology.

[17]  J. Nolz.  Molecular mechanisms of CD8+ T cell trafficking and localization , 2015, Cellular and Molecular Life Sciences.

[18]  Huafei Zou,et al.  Oxidative Stress-induced Inhibition of Sirt1 by Caveolin-1 Promotes p53-dependent Premature Senescence and Stimulates the Secretion of Interleukin 6 (IL-6)* , 2014, The Journal of Biological Chemistry.

[19]  H. Ohmatsu,et al.  Podoplanin-Positive Cancer-Associated Fibroblasts in the Tumor Microenvironment Induce Primary Resistance to EGFR-TKIs in Lung Adenocarcinoma with EGFR Mutation , 2014, Clinical Cancer Research.

[20]  R. Emerson,et al.  PD-1 blockade induces responses by inhibiting adaptive immune resistance , 2014, Nature.

[21]  S. Natsugoe,et al.  Decreased density of CD3+ tumor‐infiltrating lymphocytes during gastric cancer progression , 2014, Journal of gastroenterology and hepatology.

[22]  Nataliya Razumilava,et al.  Cholangiocarcinoma , 2014, The Lancet.

[23]  T. Pawlik,et al.  Treatment and Prognosis for Patients With Intrahepatic Cholangiocarcinoma: Systematic Review and Meta-analysis. , 2014, JAMA surgery.

[24]  J. Deursen.  The role of senescent cells in ageing , 2014, Nature.

[25]  R. Sainson,et al.  Regulation of the anti-tumour immune response by cancer-associated fibroblasts. , 2014, Seminars in cancer biology.

[26]  F. Sotgia,et al.  Catabolic cancer-associated fibroblasts transfer energy and biomass to anabolic cancer cells, fueling tumor growth. , 2014, Seminars in cancer biology.

[27]  Derek S. Chan,et al.  Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti–PD-L1 immunotherapy in pancreatic cancer , 2013, Proceedings of the National Academy of Sciences.

[28]  E. Puré,et al.  Targeting Fibroblast Activation Protein in Tumor Stroma with Chimeric Antigen Receptor T Cells Can Inhibit Tumor Growth and Augment Host Immunity without Severe Toxicity , 2013, Cancer Immunology Research.

[29]  Contents of Forthcoming Issues · Themenvorschau , 2012, Breast Care.

[30]  H. Thomas,et al.  Guidelines for the diagnosis and treatment of cholangiocarcinoma: an update , 2012, Gut.

[31]  F. Sotgia,et al.  Using the “reverse Warburg effect” to identify high-risk breast cancer patients , 2012, Cell cycle.

[32]  Q. Gao,et al.  Intratumoral IL-17+ Cells and Neutrophils show Strong Prognostic Significance in Intrahepatic Cholangiocarcinoma , 2012, Annals of Surgical Oncology.

[33]  Ricardo Garcia,et al.  Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis , 2011, Cell.

[34]  C. Ma,et al.  Colorectal Cancer–Derived Foxp3+IL‐17+ T Cells Suppress Tumour‐Specific CD8+ T Cells , 2011, Scandinavian journal of immunology.

[35]  D. Yin,et al.  CD8+ cytotoxic T cell and FOXP3+ regulatory T cell infiltration in relation to breast cancer survival and molecular subtypes , 2011, Breast Cancer Research and Treatment.

[36]  E. Bilal,et al.  Molecular profiling of a lethal tumor microenvironment, as defined by stromal caveolin-1 status in breast cancers , 2011, Cell cycle.

[37]  D. Kranz.  Faculty Opinions recommendation of Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha. , 2010 .

[38]  James O. Jones,et al.  Suppression of Antitumor Immunity by Stromal Cells Expressing Fibroblast Activation Protein–α , 2010, Science.

[39]  F. Sotgia,et al.  HIF1-alpha functions as a tumor promoter in cancer-associated fibroblasts, and as a tumor suppressor in breast cancer cells , 2010, Cell cycle.

[40]  J. Campisi,et al.  The senescence-associated secretory phenotype: the dark side of tumor suppression. , 2010, Annual review of pathology.

[41]  R. Xiang,et al.  Cancer Associated Fibroblasts Promote Tumor Growth and Metastasis by Modulating the Tumor Immune Microenvironment in a 4T1 Murine Breast Cancer Model , 2009, PloS one.

[42]  F. Sotgia,et al.  An absence of stromal caveolin-1 is associated with advanced prostate cancer, metastatic disease spread and epithelial Akt activation , 2009, Cell cycle.

[43]  A. Rosenberg,et al.  Human breast cancer-associated fibroblasts (CAFs) show caveolin-1 down-regulation and RB tumor suppressor functional inactivation: Implications for the response to hormonal therapy , 2008, Cancer biology & therapy.

[44]  M. Uslenghi,et al.  The World Space Observatory (WSO-UV) - Current status , 2008, 0801.2080.

[45]  Steven C Cunningham,et al.  Cholangiocarcinoma: Thirty-one-Year Experience With 564 Patients at a Single Institution , 2007, Annals of surgery.

[46]  Raghu Kalluri,et al.  Fibroblasts in cancer , 2006, Nature Reviews Cancer.

[47]  J. Campisi,et al.  Cancer and aging: a model for the cancer promoting effects of the aging stroma. , 2002, The international journal of biochemistry & cell biology.

[48]  H Nagura,et al.  CD8+ T cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer. , 1998, Cancer research.

[49]  M. Lisanti,et al.  Caveolins, a Family of Scaffolding Proteins for Organizing “Preassembled Signaling Complexes” at the Plasma Membrane* , 1998, The Journal of Biological Chemistry.

[50]  L. Howells,et al.  The role of stromal fibroblasts in lung carcinogenesis: A target for chemoprevention? , 2016, International journal of cancer.