TNP-ATP is Beneficial for Treatment of Neonatal Hypoxia-Induced Hypomyelination and Cognitive Decline

[1]  Zhengqian Li,et al.  Duration-dependent regulation of autophagy by isoflurane exposure in aged rats , 2015, Neuroscience Bulletin.

[2]  Â. R. Tomé,et al.  ATP as a multi-target danger signal in the brain , 2015, Front. Neurosci..

[3]  Junbo Xie,et al.  Hplc-ESI-MS/MS analysis of the water-soluble extract from Ziziphi spinosae semen and its ameliorating effect of learning and memory performance in mice , 2014, Pharmacognosy magazine.

[4]  N. Jones,et al.  The effects of hypoxic preconditioning on white matter damage following hypoxic-ischaemic injury in the neonatal rat brain , 2014, International Journal of Developmental Neuroscience.

[5]  L. Gofman,et al.  P2X4 Receptor Regulates Alcohol-Induced Responses in Microglia , 2014, Journal of Neuroimmune Pharmacology.

[6]  Shuang Qiu,et al.  Clustering of surface NMDA receptors is mainly mediated by the C-terminus of GluN2A in cultured rat hippocampal neurons , 2014, Neuroscience Bulletin.

[7]  G. Rådegran,et al.  P2Y1 and P2Y12 receptors in hypoxia- and adenosine diphosphate-induced pulmonary vasoconstriction in vivo in the pig , 2014, European Journal of Applied Physiology.

[8]  A. Khodorova,et al.  Sensitization of cutaneous neuronal purinergic receptors contributes to endothelin-1-induced mechanical hypersensitivity , 2014, PAIN®.

[9]  Chunbo Chen,et al.  Astrocyte-Derived Proinflammatory Cytokines Induce Hypomyelination in the Periventricular White Matter in the Hypoxic Neonatal Brain , 2014, PloS one.

[10]  M. Lepage,et al.  Involvement of neuronal IL-1β in acquired brain lesions in a rat model of neonatal encephalopathy , 2013, Journal of Neuroinflammation.

[11]  M. Hediger,et al.  Investigation of the Inhibitory Effects of the Benzodiazepine Derivative, 5-BDBD on P2X4 Purinergic Receptors by two Complementary Methods , 2013, Cellular Physiology and Biochemistry.

[12]  Jurong Yang,et al.  ATP-P2X4 signaling mediates NLRP3 inflammasome activation: a novel pathway of diabetic nephropathy. , 2013, The international journal of biochemistry & cell biology.

[13]  B. Fredholm,et al.  Adenosine receptors as drug targets — what are the challenges? , 2013, Nature Reviews Drug Discovery.

[14]  R. Gum,et al.  P2X receptor antagonists for pain management: examination of binding and physicochemical properties , 2012, Purinergic Signalling.

[15]  Lei Wang,et al.  Hypoxia induced amoeboid microglial cell activation in postnatal rat brain is mediated by ATP receptor P2X4 , 2011, BMC Neuroscience.

[16]  Stuart G. Cull-Candy,et al.  Bidirectional plasticity of calcium-permeable AMPA receptors in oligodendrocyte lineage cells , 2011, Nature Neuroscience.

[17]  E. Hutchinson,et al.  Chronic Neurological Deficits in Mice after Perinatal Hypoxia and Ischemia Correlate with Hemispheric Tissue Loss and White Matter Injury Detected by MRI , 2011, Developmental Neuroscience.

[18]  Susumu Mori,et al.  In vivo Magnetization Transfer MRI Shows Dysmyelination in an Ischemic Mouse Model of Periventricular Leukomalacia , 2011, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[19]  A. Nuttall,et al.  Functional expression of P2X4 receptor in capillary endothelial cells of the cochlear spiral ligament and its role in regulating the capillary diameter. , 2011, American journal of physiology. Heart and circulatory physiology.

[20]  E. Romero-Sandoval,et al.  Inhibition of microglial P2X4 receptors attenuates morphine tolerance, Iba1, GFAP and μ opioid receptor protein expression while enhancing perivascular microglial ED2 , 2010, PAIN.

[21]  F. Fang,et al.  Increased hippocampal T2 in a rat model of pentylenetetrazol-induced kindling correlates with seizure scores , 2010, Journal of the Neurological Sciences.

[22]  L. D. de Vries,et al.  Long-term outcome after neonatal hypoxic-ischaemic encephalopathy , 2010, Archives of Disease in Childhood: Fetal and Neonatal Edition.

[23]  E. Ling,et al.  Role of glutamate and its receptors and insulin‐like growth factors in hypoxia induced periventricular white matter injury , 2010, Glia.

[24]  P. Cheung,et al.  Long-term cognitive impairment and myelination deficiency in a rat model of perinatal hypoxic-ischemic brain injury , 2009, Brain Research.

[25]  E. Ling,et al.  Periventricular white matter damage in the hypoxic neonatal brain: Role of microglial cells , 2009, Progress in Neurobiology.

[26]  J. Deleo,et al.  Morphine Enhances Microglial Migration through Modulation of P2X4 Receptor Signaling , 2009, The Journal of Neuroscience.

[27]  H. Tozaki-Saitoh,et al.  Behavioral phenotypes of mice lacking purinergic P2X4 receptors in acute and chronic pain assays , 2009, Molecular pain.

[28]  Silun Wang,et al.  Characterization of White Matter Injury in a Hypoxic-Ischemic Neonatal Rat Model by Diffusion Tensor MRI , 2008, Stroke.

[29]  D. Rossi,et al.  Astrocyte metabolism and signaling during brain ischemia , 2007, Nature Neuroscience.

[30]  M. Robinson,et al.  The role of glutamate transporters in neurodegenerative diseases and potential opportunities for intervention , 2007, Neurochemistry International.

[31]  Jing Liu,et al.  [Expression of caveolin-1 protein in the rat brain and its role in the discrimination learning]. , 2006, Sheng li xue bao : [Acta physiologica Sinica].

[32]  G. Burnstock.  Purinergic P2 receptors as targets for novel analgesics. , 2006, Pharmacology & therapeutics.

[33]  A. Schousboe,et al.  Glial modulation of GABAergic and glutamat ergic neurotransmission. , 2006, Current topics in medicinal chemistry.

[34]  U. Tuor,et al.  Evolution of Magnetic Resonance Imaging Changes Associated with Cerebral Hypoxia-Ischemia and a Relatively Selective White Matter Injury in Neonatal Rats , 2006, Pediatric Research.

[35]  A. Hazell,et al.  Excitotoxic mechanisms and the role of astrocytic glutamate transporters in traumatic brain injury , 2006, Neurochemistry International.

[36]  J. Gu,et al.  P2X purinoceptors and sensory transmission , 2006, Pflügers Archiv.

[37]  S. Koizumi,et al.  P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury , 2003, Nature.

[38]  G. Burnstock,et al.  Effects of P2-purinoceptor antagonists on degradation of adenine nucleotides by ecto-nucleotidases in folliculated oocytes of Xenopus laevis. , 1996, Biochemical pharmacology.

[39]  C. Ikonomidou,et al.  Hypobaric-ischemic conditions produce glutamate-like cytopathology in infant rat brain , 1989, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[40]  E. Ling,et al.  Microglia-derived proinflammatory cytokines tumor necrosis factor-alpha and interleukin-1beta induce Purkinje neuronal apoptosis via their receptors in hypoxic neonatal rat brain , 2012, Brain Structure and Function.

[41]  P. Svenningsson,et al.  Adenosine and brain function. , 2005, International review of neurobiology.

[42]  Jie Ying Gao,et al.  Increased detectability of alpha brain glutamate/glutamine in neonatal hypoxic-ischemic encephalopathy. , 2000, AJNR. American journal of neuroradiology.