Points of control in inflammation

[1]  C. Esmon.  Coagulation and inflammation , 2001, Journal of endotoxin research.

[2]  H. Erdjument-Bromage,et al.  Conversion of Proepithelin to Epithelins Roles of SLPI and Elastase in Host Defense and Wound Repair , 2002, Cell.

[3]  G. Cooke,et al.  Toll-like receptor 4 polymorphisms and atherogenesis. , 2002, The New England journal of medicine.

[4]  C. Benoist,et al.  Mast Cells: A Cellular Link Between Autoantibodies and Inflammatory Arthritis , 2002, Science.

[5]  Eugene Y. Kim,et al.  Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A4 , 2002, Nature Medicine.

[6]  A. Thatayatikom,et al.  Mutation of a New Gene Encoding a Putative Pyrin-Like Protein Causes Familial Cold Autoinflammatory Syndrome and Muckle-Wells Syndrome , 2002, Pediatrics.

[7]  J. Liao.  Isoprenoids as mediators of the biological effects of statins. , 2002, The Journal of clinical investigation.

[8]  K. Okkenhaug,et al.  Impaired B and T Cell Antigen Receptor Signaling in p110δ PI 3-Kinase Mutant Mice , 2002, Science.

[9]  T. Misteli,et al.  Release of chromatin protein HMGB1 by necrotic cells triggers inflammation , 2002, Nature.

[10]  G. Courtois,et al.  TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2 , 2002, Nature.

[11]  L. Samelson,et al.  A LAT Mutation That Inhibits T Cell Development Yet Induces Lymphoproliferation , 2002, Science.

[12]  W. Ruf,et al.  Activation of Endothelial Cell Protease Activated Receptor 1 by the Protein C Pathway , 2002, Science.

[13]  E. Wakeland,et al.  Genetic Modifiers of Systemic Lupus Erythematosus in FcγRIIB−/− Mice , 2002, The Journal of experimental medicine.

[14]  W. Muller,et al.  Leukocyte-Endothelial Cell Interactions in the Inflammatory Response , 2002, Laboratory Investigation.

[15]  Charles A. Janeway,et al.  Decoding the Patterns of Self and Nonself by the Innate Immune System , 2002, Science.

[16]  P. Matzinger.  The Danger Model: A Renewed Sense of Self , 2002, Science.

[17]  E. Puré,et al.  Resolution of Lung Inflammation by CD44 , 2002, Science.

[18]  A. Fornace,et al.  Mice lacking the p53-effector gene Gadd45a develop a lupus-like syndrome. , 2002, Immunity.

[19]  Akira Takashima,et al.  CD39 is the dominant Langerhans cell–associated ecto-NTPDase: Modulatory roles in inflammation and immune responsiveness , 2002, Nature Medicine.

[20]  M. Silverberg,et al.  Pathways for bradykinin formation and inflammatory disease. , 2002, The Journal of allergy and clinical immunology.

[21]  S. Szabo,et al.  Development of Spontaneous Airway Changes Consistent with Human Asthma in Mice Lacking T-bet , 2002, Science.

[22]  G. Zimmerman,et al.  Leukocyte adhesion deficiency syndromes: adhesion and tethering defects involving beta 2 integrins and selectin ligands. , 2002, Current opinion in hematology.

[23]  A. Ohta,et al.  Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage , 2001, Nature.

[24]  D. Kastner,et al.  A fever gene comes in from the cold , 2001, Nature Genetics.

[25]  Joseph Keane,et al.  Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent , 2001 .

[26]  G. Thomas,et al.  CARD15 mutations in Blau syndrome , 2001, Nature Genetics.

[27]  K. Tracey,et al.  Dual roles for HMGB1: DNA binding and cytokine , 2001, Journal of endotoxin research.

[28]  D. Friend,et al.  Increased Severity of Local and Systemic Anaphylactic Reactions in Gp49b1-Deficient Mice , 2001, The Journal of experimental medicine.

[29]  I. Kluijt,et al.  A family with complement factor D deficiency. , 2001, The Journal of clinical investigation.

[30]  Charles N. Serhan,et al.  Lipid mediator class switching during acute inflammation: signals in resolution , 2001, Nature Immunology.

[31]  Mourad Sahbatou,et al.  Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease , 2001, Nature.

[32]  Judy H. Cho,et al.  A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease , 2001, Nature.

[33]  Yann Leverrier,et al.  Cutting Edge: The Wiskott-Aldrich Syndrome Protein Is Required for Efficient Phagocytosis of Apoptotic Cells1 , 2001, The Journal of Immunology.

[34]  S. Yamaoka,et al.  Nod2, a Nod1/Apaf-1 Family Member That Is Restricted to Monocytes and Activates NF-κB* , 2001, The Journal of Biological Chemistry.

[35]  J. Keane,et al.  Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent. , 2001, The New England journal of medicine.

[36]  B. Blom,et al.  Down-regulation of the macrophage lineage through interaction with OX2 (CD200). , 2000, Science.

[37]  D. Lipsker,et al.  Lupus erythematosus associated with genetically determined deficiency of the second component of the complement. , 2000, Archives of dermatology.

[38]  D. Jäger,et al.  The Leukotriene C4 Transporter MRP1 Regulates CCL19 (MIP-3β, ELC)–Dependent Mobilization of Dendritic Cells to Lymph Nodes , 2000, Cell.

[39]  G. Kelsoe,et al.  Complement C4 Inhibits Systemic Autoimmunity through a Mechanism Independent of Complement Receptors Cr1 and Cr2 , 2000, The Journal of experimental medicine.

[40]  P. Srivastava,et al.  Heat shock proteins: the fountainhead of innate and adaptive immune responses , 2000, Cell stress & chaperones.

[41]  A. Kulkarni,et al.  Secretory leukocyte protease inhibitor mediates non-redundant functions necessary for normal wound healing , 2000, Nature Medicine.

[42]  F. Weih,et al.  Mice lacking the transcription factor RelB develop T cell‐dependent skin lesions similar to human atopic dermatitis , 2000, European journal of immunology.

[43]  Klaus Rajewsky,et al.  NEMO/IKKγ-Deficient Mice Model Incontinentia Pigmenti , 2000 .

[44]  V. Godfrey,et al.  Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti. , 2000, Molecular cell.

[45]  T. Möröy,et al.  Features of systemic lupus erythematosus in Dnase1-deficient mice , 2000, Nature Genetics.

[46]  S. Klauck,et al.  Genomic rearrangement in NEMO impairs NF-κB activation and is a cause of incontinentia pigmenti , 2000, Nature.

[47]  M Ikegami,et al.  Increased metalloproteinase activity, oxidant production, and emphysema in surfactant protein D gene-inactivated mice. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[48]  S. Holland,et al.  Genetic, biochemical, and clinical features of chronic granulomatous disease. , 2000, Medicine.

[49]  L. Hydo,et al.  Secretory leukocyte protease inhibitor, an inhibitor of neutrophil activation, is elevated in serum in human sepsis and experimental endotoxemia , 2000, Critical care medicine.

[50]  M. Serrano,et al.  The cell cycle inhibitor p21 controls T-cell proliferation and sex-linked lupus development , 2000, Nature Medicine.

[51]  J. Wallace,et al.  Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism , 2000, Nature Medicine.

[52]  B. Palanca,et al.  A critical role for murine complement regulator crry in fetomaternal tolerance. , 2000, Science.

[53]  G. Duff,et al.  Arterial Inflammation in Mice Lacking the Interleukin 1 Receptor Antagonist Gene , 2000, The Journal of experimental medicine.

[54]  S. Nakae,et al.  Development of Chronic Inflammatory Arthropathy Resembling Rheumatoid Arthritis in Interleukin 1 Receptor Antagonist–Deficient Mice , 2000, The Journal of experimental medicine.

[55]  H. Nishina,et al.  Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b , 2000, Nature.

[56]  Ji Ming Wang,et al.  β-Defensins: Linking Innate and Adaptive Immunity Through Dendritic and T Cell CCR6 , 1999 .

[57]  P. Pandolfi,et al.  Impaired Fas response and autoimmunity in Pten+/- mice. , 1999, Science.

[58]  Paul J Hertzog,et al.  SOCS1 Is a Critical Inhibitor of Interferon γ Signaling and Prevents the Potentially Fatal Neonatal Actions of this Cytokine , 1999, Cell.

[59]  S. Buys,et al.  The spectrum of apoptotic defects and clinical manifestations, including systemic lupus erythematosus, in humans with CD95 (Fas/APO-1) mutations. , 1999, Arthritis and rheumatism.

[60]  T. Honjo,et al.  Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. , 1999, Immunity.

[61]  P. Butler,et al.  Serum amyloid P component controls chromatin degradation and prevents antinuclear autoimmunity , 1999, Nature Medicine.

[62]  H. Waterham,et al.  Mutations in MVK, encoding mevalonate kinase, cause hyperimmunoglobulinaemia D and periodic fever syndrome , 1999, Nature Genetics.

[63]  Joost P.H. Drenth,et al.  Mutations in the gene encoding mevalonate kinase cause hyper-IgD and periodic fever syndrome , 1999, Nature Genetics.

[64]  Ian Todd,et al.  Germline Mutations in the Extracellular Domains of the 55 kDa TNF Receptor, TNFR1, Define a Family of Dominantly Inherited Autoinflammatory Syndromes , 1999, Cell.

[65]  K. Sullivan.  Complement deficiency and autoimmunity. , 1998, Current opinion in pediatrics.

[66]  J. C. Jones,et al.  A novel model of inflammatory bowel disease: mice deficient for the multiple drug resistance gene, mdr1a, spontaneously develop colitis. , 1998, Journal of immunology.

[67]  Christopher A. Hunter,et al.  Inhibition of interferon γ induced interleukin 12 production: A potential mechanism for the anti-inflammatory activities of tumor necrosis factor , 1998 .

[68]  L. Glimcher,et al.  Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development. , 1998, Immunity.

[69]  D. Neuberg,et al.  Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[70]  Philip R. Cohen,et al.  Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation. , 1998, Immunity.

[71]  G. Krystal,et al.  Targeted disruption of SHIP leads to hemopoietic perturbations, lung pathology, and a shortened life span. , 1998, Genes & development.

[72]  Pier Paolo Pandolfi,et al.  Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies , 1998, Nature Genetics.

[73]  Hideaki Ishikawa,et al.  Chronic Inflammation and Susceptibility to Bacterial Infections in Mice Lacking the Polypeptide (p)105 Precursor (NF-κB1) but Expressing p50 , 1998, The Journal of experimental medicine.

[74]  N. Copeland,et al.  The itchy locus encodes a novel ubiquitin protein ligase that is disrupted in a18H mice , 1998, Nature Genetics.

[75]  M. Horton,et al.  Inhibition of interferon g induced interleukin 12 production : A potential mechanism for the anti-inflammatory activities of tumor necrosis factor , 1998 .

[76]  C. Nathan,et al.  Perspectives Series : Nitric Oxide and Nitric Oxide Synthases Inducible Nitric Oxide Synthase : What Difference Does It Make ? , 2013 .

[77]  S. Tonegawa,et al.  Heme oxygenase 1 is required for mammalian iron reutilization. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[78]  Jacques Demaille,et al.  A candidate gene for familial Mediterranean fever , 1997, Nature Genetics.

[79]  F. Collins,et al.  Ancient Missense Mutations in a New Member of the RoRet Gene Family Are Likely to Cause Familial Mediterranean Fever , 1997, Cell.

[80]  L. Old,et al.  Characterization of tumor necrosis factor-deficient mice. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[81]  M. Botto,et al.  Complement Deficiency and Autoimmunity a , 1997, Annals of the New York Academy of Sciences.

[82]  D. Radzioch,et al.  Secretory Leukocyte Protease Inhibitor: A Macrophage Product Induced by and Antagonistic to Bacterial Lipopolysaccharide , 1997, Cell.

[83]  M. Dinauer,et al.  Absence of Respiratory Burst in X-linked Chronic Granulomatous Disease Mice Leads to Abnormalities in Both Host Defense and Inflammatory Response to Aspergillus fumigatus , 1997, The Journal of experimental medicine.

[84]  C. Stewart,et al.  IkappaBalpha deficiency results in a sustained NF-kappaB response and severe widespread dermatitis in mice , 1996, Molecular and cellular biology.

[85]  B. Haynes,et al.  A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency. , 1996, Immunity.

[86]  A. Morales.  Intravesical therapy of bladder cancer : An immunotherapy success story , 1996 .

[87]  J. F. Klement,et al.  IkBa Deficiency Results in a Sustained NF-kB Response and Severe Widespread Dermatitis in Mice , 1996 .

[88]  H. Griesser,et al.  Lymphoproliferative Disorders with Early Lethality in Mice Deficient in Ctla-4 , 1995, Science.

[89]  J. Bluestone,et al.  Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. , 1995, Immunity.

[90]  T. Yamamoto,et al.  Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice. , 1995, Immunity.

[91]  S. Stacker,et al.  Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease , 1995, Cell.

[92]  F. Alt,et al.  Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment. , 1995, Immunity.

[93]  Warren Strober,et al.  Dominant interfering fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome , 1995, Cell.

[94]  A. Bradley,et al.  Ulcerative colitis and adenocarcinoma of the colon in Gαi2-deficient mice , 1995, Nature Genetics.

[95]  D. Lo,et al.  Expression of relB is required for the development of thymic medulla and dendritic cells , 1995, Nature.

[96]  F. Weih,et al.  Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-κB/Rel family , 1995, Cell.

[97]  Fink Mp.  Effect of critical illness on microbial translocation and gastrointestinal mucosa permeability. , 1994 .

[98]  K. Sullivan,et al.  A multiinstitutional survey of the Wiskott-Aldrich syndrome. , 1994, The Journal of pediatrics.

[99]  G. Dranoff,et al.  Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis. , 1994, Science.

[100]  M. Fink.  Effect of critical illness on microbial translocation and gastrointestinal mucosa permeability. , 1994, Seminars in respiratory infections.

[101]  A. Feller,et al.  Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene , 1993, Cell.

[102]  S. Tonegawa,et al.  Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice , 1993, Cell.

[103]  K. Rajewsky,et al.  Interleukin-10-deficient mice develop chronic enterocolitis , 1993, Cell.

[104]  D. Beier,et al.  Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene , 1993, Cell.

[105]  C. Nathan,et al.  Albumin inhibits neutrophil spreading and hydrogen peroxide release by blocking the shedding of CD43 (sialophorin, leukosialin) , 1993, The Journal of cell biology.

[106]  K. Siminovitch,et al.  Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene , 1993, Nature Genetics.

[107]  M. Sporn,et al.  Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[108]  G. Proetzel,et al.  Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease , 1992, Nature.

[109]  E. Jaffe,et al.  A novel lymphoproliferative/autoimmune syndrome resembling murine lpr/gld disease. , 1992, The Journal of clinical investigation.

[110]  J. Larrick,et al.  Human neutrophil granule cationic protein CAP37 is a specific macrophage chemotaxin that shares homology with inflammatory proteinases. , 1991, Advances in experimental medicine and biology.

[111]  R. Eisenberg,et al.  Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease. , 1991, Annual review of immunology.

[112]  A. Lazzarin,et al.  [The inflammatory process]. , 1990, Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale.

[113]  S. Weiss.  Tissue destruction by neutrophils. , 1989, The New England journal of medicine.

[114]  C. Nathan.  Neutrophil activation on biological surfaces. Massive secretion of hydrogen peroxide in response to products of macrophages and lymphocytes. , 1987, The Journal of clinical investigation.

[115]  H. Carp.  Mitochondrial N-formylmethionyl proteins as chemoattractants for neutrophils , 1982, The Journal of experimental medicine.

[116]  R. Clark,et al.  Chemotactic factor inactivation by the myeloperoxidase-hydrogen peroxide-halide system. , 1979, The Journal of clinical investigation.

[117]  P. Schur.  Genetics of complement deficiencies associated with lupus-like syndromes. , 1978, Arthritis and rheumatism.