[Colorectal stapled anastomosis: results after anterior resection of the rectum for cancer].

OBJECTIVE Stapled end to end anastomosis makes the restoration of digestive continuity at the level of lower pelvis easier, but carries a certain risk. The aim of this report was to evaluate this risk in terms of immediate results and tumor recurrence after surgery for rectal cancer. PATIENTS AND METHODS The data of 301 patients operated on following this technique between 1980 and 2000 have been reviewed in order to analyse the tumor characteristics, the operation and associated complications, the immediate postoperative complications and recurrence rate. RESULTS Among the 301 patients (192 males and 109 females) with median age of 66 years, 19 (6.3%) received an emergency operation due to bowel obstruction. The rectal adenocarcinoma was located in the upper rectum in 132 cases (43.8%), in the middle rectum in 141 cases (46.8%) and in the lower rectum in 19 cases (9.4%). Preoperative radiotherapy was carried out in 148 cases (49%): between 1987 and 1996 with a dose of 30 Grays (Gy), later increased to 39 Gy and 45 Gy in 12 cases. From 1990, 113 patients have received adjuvant chemotherapy for stage III and IV tumors and in some position cases for stage II tumor. The excision left a safety margin under the tumor of less than 2 cm in 59 cases (19.6%), and the anastomosis was located at 5 cm or less from the anal verge in 178 cases (59%). Primary defunctioning stoma was formed in 39 cases (13%). An anastomotic defect was observed during the operation in 18 cases (6%) and 26 fistulas occured postoperatively (7.6%), significantly related to the location of the anastomosis with regard to the anal verge (P = 0.0009). The hospital mortality was 8 cases (2.6%). Cases of stenosis were uncommon : 11 cases (3.6%), significantly associated with preoperative radiotherapy (P =0.02). The local recurrence rate was 12% (37 cases) in a median time delay of 16 months, essentially related to the tumor stage (P = 0.004) and the considered period (P = 0.001). CONCLUSION Stapled end-to-end colorectal anastomosis after excision of rectum for cancer is a reliable technique with a low rate of complication and tumor recurrence, when the surgical procedure is included in the curative therapy management of cancer.

[1]  I. Nagtegaal,et al.  The role of pathologists in the quality control of diagnosis and treatment of rectal cancer-an overview. , 2002, European journal of cancer.

[2]  E. Weiss,et al.  Colonic J-pouch function in rectal cancer patients , 2001, Diseases of the colon and rectum.

[3]  C. Vaccaro,et al.  Rectal Cancer: Local Recurrence After Surgery Without Radiotherapy , 2001 .

[4]  W. Law,et al.  Risk factors for anastomotic leakage after low anterior resection with total mesorectal excision. , 2000, American Journal of Surgery.

[5]  B. Topal,et al.  Outcome after ‘curative’ surgery for carcinoma of the lower third of the rectum , 1998, The British journal of surgery.

[6]  E. Schlichting,et al.  Effect of the introduction of total mesorectal excision for the treatment of rectal cancer , 1998, The British journal of surgery.

[7]  H. Järvinen,et al.  Anastomotic leakage after anterior resection of the rectum. , 1994, The European journal of surgery = Acta chirurgica.

[8]  M. Mohiuddin,et al.  Patterns of recurrence following high-dose preoperative radiation and sphincter-preserving surgery for cancer of the rectum , 1993, Diseases of the colon and rectum.

[9]  P. Roberts,et al.  Pitfalls in use of stapler in gastrointestinal tract surgery. , 1991, The Surgical clinics of North America.

[10]  R. Heald,et al.  ‘Close shave’ in anterior resection , 1990, The British journal of surgery.

[11]  J. Tuson,et al.  A retrospective study of colostomies, leaks and strictures after colorectal anastomosis , 1990, International Journal of Colorectal Disease.

[12]  A. Senagore,et al.  Colorectal anastomotic stenosis results of a survey of the ASCRS membership , 1989, Diseases of the colon and rectum.

[13]  P. Quirke,et al.  LOCAL RECURRENCE OF RECTAL ADENOCARCINOMA DUE TO INADEQUATE SURGICAL RESECTION Histopathological Study of Lateral Tumour Spread and Surgical Excision , 1986, The Lancet.

[14]  R. Beart Surgery of the Anus, Rectum and Colon , 1984 .

[15]  C. Dukes,et al.  The classification of cancer of the rectum , 1980 .

[16]  M. Ravitch Intersecting staple lines in intestinal anastomoses. , 1985, Surgery.

[17]  J. Overgaard,et al.  Dose-response relationship for radiation therapy of recurrent, residual, and primarily inoperable colorectal cancer. , 1984, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[18]  F. D. Griffen,et al.  An improved technique for low anterior resection of the rectum using the EEA stapler. , 1980, Surgery.