Influenza A virus NS1 protein binds p85β and activates phosphatidylinositol-3-kinase signaling
暂无分享,去创建一个
Richard E. Randall | R. Lamb | B. G. Hale | R. Randall | Robert A. Lamb | David Jackson | Benjamin G. Hale | Yun-Hsiang Chen | Yun-Hsiang Chen | D. Jackson
[1] B. Prasad,et al. X-ray structure of influenza virus NS1 effector domain , 2006, Nature Structural &Molecular Biology.
[2] R. Randall,et al. Interferon-Induced Alterations in the Pattern of Parainfluenza Virus 5 Transcription and Protein Synthesis and the Induction of Virus Inclusion Bodies , 2005, Journal of Virology.
[3] R. Webster,et al. Lethal H5N1 influenza viruses escape host anti-viral cytokine responses , 2002, Nature Medicine.
[4] David E. Swayne,et al. Sequence of the 1918 pandemic influenza virus nonstructural gene (NS) segment and characterization of recombinant viruses bearing the 1918 NS genes , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[5] M. Amorim,et al. Lipid Raft‐Dependent Targeting of the Influenza A Virus Nucleoprotein to the Apical Plasma Membrane , 2004, Traffic.
[6] Kathryn L. Parsley,et al. High-level transduction and gene expression in hematopoietic repopulating cells using a human imunodeficiency virus type 1-based lentiviral vector containing an internal spleen focus forming virus promoter , 2002 .
[7] Lewis C Cantley,et al. The phosphoinositide 3-kinase pathway. , 2002, Science.
[8] S. Goodbourn,et al. Variation in the ability of human influenza A viruses to induce and inhibit the IFN-beta pathway. , 2006, Virology.
[9] I Gout,et al. Expression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85 beta protein by using the baculovirus expression system. , 1992, The Biochemical journal.
[10] Amer A. Beg,et al. Influenza A Virus NS1 Protein Prevents Activation of NF-κB and Induction of Alpha/Beta Interferon , 2000, Journal of Virology.
[11] Kohjiro Ueki,et al. Increased insulin sensitivity in mice lacking p85β subunit of phosphoinositide 3-kinase , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[12] R. Krug,et al. The 3'-end-processing factor CPSF is required for the splicing of single-intron pre-mRNAs in vivo. , 2001, RNA.
[13] Tokiko Watanabe,et al. Generation of influenza A viruses entirely from cloned cDNAs. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[14] M. Katze,et al. Binding of the influenza virus NS1 protein to double-stranded RNA inhibits the activation of the protein kinase that phosphorylates the elF-2 translation initiation factor. , 1995, Virology.
[15] M. Katze,et al. Biochemical and genetic evidence for complex formation between the influenza A virus NS1 protein and the interferon-induced PKR protein kinase. , 1998, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.
[16] S. Goodbourn,et al. The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[17] R. Krug,et al. The primary function of RNA binding by the influenza A virus NS1 protein in infected cells: Inhibiting the 2'-5' oligo (A) synthetase/RNase L pathway. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[18] A. García-Sastre,et al. Inhibition of interferon-mediated antiviral responses by influenza A viruses and other negative-strand RNA viruses. , 2001, Virology.
[19] Thorsten Wolff,et al. Bivalent role of the phosphatidylinositol‐3‐kinase (PI3K) during influenza virus infection and host cell defence , 2006, Cellular microbiology.
[20] P. Palese,et al. Two nuclear location signals in the influenza virus NS1 nonstructural protein , 1988, Journal of virology.
[21] B. Hemmings,et al. Advances in protein kinase B signalling: AKTion on multiple fronts. , 2004, Trends in biochemical sciences.
[22] G. Trinchieri. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. , 1995, Annual review of immunology.
[23] J. Dodge,et al. Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase. , 1994, Cancer research.
[24] R. Krug,et al. Intracellular warfare between human influenza viruses and human cells: the roles of the viral NS1 protein. , 2003, Virology.
[25] D. Cantrell. Phosphoinositide 3-kinase signalling pathways. , 2001, Journal of cell science.
[26] R. Randall,et al. Isolation and characterization of monoclonal antibodies to simian virus 5 and their use in revealing antigenic differences between human, canine and simian isolates. , 1987, The Journal of general virology.
[27] D. Alessi,et al. Regulation of Akt/PKB Ser473 phosphorylation. , 2005, Molecular cell.
[28] T. Asano,et al. PI3K-mediated negative feedback regulation of IL-12 production in DCs , 2002, Nature Immunology.
[29] J. Klein,et al. Positive and Negative Roles of p85α and p85β Regulatory Subunits of Phosphoinositide 3-Kinase in Insulin Signaling* , 2003, Journal of Biological Chemistry.
[30] Ryuji Fukuda,et al. Mutant Influenza Viruses with a Defective NS1 Protein Cannot Block the Activation of PKR in Infected Cells , 1999, Journal of Virology.
[31] Thomas M. Moran,et al. Influenza Virus Evades Innate and Adaptive Immunity via the NS1 Protein , 2006, Journal of Virology.
[32] R. Krug,et al. The influenza virus NS1 protein is a poly(A)-binding protein that inhibits nuclear export of mRNAs containing poly(A) , 1994, Journal of virology.
[33] S. Goodbourn,et al. In vitro and in vivo specificity of ubiquitination and degradation of STAT1 and STAT2 by the V proteins of the paramyxoviruses simian virus 5 and human parainfluenza virus type 2. , 2005, The Journal of general virology.
[34] R. Krug,et al. Influenza virus NS1 protein interacts with the cellular 30 kDa subunit of CPSF and inhibits 3'end formation of cellular pre-mRNAs. , 1998, Molecular cell.
[35] R. Krug,et al. Binding of the influenza A virus NS1 protein to PKR mediates the inhibition of its activation by either PACT or double-stranded RNA. , 2006, Virology.
[36] T. Pawson,et al. SH2 domains recognize specific phosphopeptide sequences , 1993, Cell.
[37] R. Krug,et al. Influenza virus virulence and its molecular determinants. , 2005, Advances in virus research.
[38] D. Levy,et al. Influenza A virus lacking the NS1 gene replicates in interferon-deficient systems. , 1998, Virology.
[39] K Y Hui,et al. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). , 1994, The Journal of biological chemistry.
[40] R. Krug,et al. Influenza A virus NS1 protein targetspoly(A)‐binding protein II of the cellular 3′‐end processing machinery , 1999, The EMBO journal.
[41] A. Bilancio,et al. Signalling by PI3K isoforms: insights from gene-targeted mice. , 2005, Trends in biochemical sciences.
[42] A. García-Sastre,et al. Activation of Interferon Regulatory Factor 3 Is Inhibited by the Influenza A Virus NS1 Protein , 2000, Journal of Virology.
[43] B. Hemmings,et al. Ten years of protein kinase B signalling: a hard Akt to follow. , 2001, Trends in biochemical sciences.
[44] S. Cooray,et al. The pivotal role of phosphatidylinositol 3-kinase-Akt signal transduction in virus survival. , 2004, The Journal of general virology.
[45] R. Lamb,et al. Influenza A Virus M2 Ion Channel Activity Is Essential for Efficient Replication in Tissue Culture , 2002, Journal of Virology.
[46] R. Randall,et al. Identification of an epitope on the P and V proteins of simian virus 5 that distinguishes between two isolates with different biological characteristics. , 1991, The Journal of general virology.
[47] Sangdun Choi,et al. Enhanced T Cell Proliferation in Mice Lacking the p85β Subunit of Phosphoinositide 3-Kinase1 , 2004, The Journal of Immunology.
[48] R. Krug,et al. Cellular antiviral responses against influenza A virus are countered at the posttranscriptional level by the viral NS1A protein via its binding to a cellular protein required for the 3' end processing of cellular pre-mRNAS. , 2003, Virology.
[49] S. Goodbourn,et al. Simian Virus 5 V Protein Acts as an Adaptor, Linking DDB1 to STAT2, To Facilitate the Ubiquitination of STAT1 , 2005, Journal of Virology.
[50] S. Corvera,et al. Specific Association of the β Isoform of the p85 Subunit of Phosphatidylinositol-3 Kinase with the Proto-oncogene c-cbl(*) , 1995, The Journal of Biological Chemistry.