Protective effect of andrographolide against concanavalin A-induced liver injury

[1]  S. Mandal,et al.  Recent advances in herbal medicine for treatment of liver diseases , 2011, Pharmaceutical biology.

[2]  Hen-Hong Chang,et al.  Andrographolide acts as an anti-inflammatory agent in LPS-stimulated RAW264.7 macrophages by inhibiting STAT3-mediated suppression of the NF-κB pathway. , 2011, Journal of ethnopharmacology.

[3]  C. Chern,et al.  Andrographolide Inhibits PI3K/AKT-Dependent NOX2 and iNOS Expression Protecting Mice against Hypoxia/Ischemia-Induced Oxidative Brain Injury , 2011, Planta medica.

[4]  I. Beis,et al.  Insulin-induced oxidative stress up-regulates heme oxygenase-1 via diverse signaling cascades in the C2 skeletal myoblast cell line. , 2011, Endocrinology.

[5]  T. Sakuma,et al.  Cellular glutathione content modulates the effect of andrographolide on β-naphthoflavone-induced CYP1A1 mRNA expression in mouse hepatocytes. , 2011, Toxicology.

[6]  F. Chou,et al.  Andrographolide down-regulates hypoxia-inducible factor-1α in human non-small cell lung cancer A549 cells. , 2011, Toxicology and applied pharmacology.

[7]  G. Ning,et al.  Andrographolide attenuates tumor necrosis factor-alpha-induced insulin resistance in 3T3-L1 adipocytes , 2011, Molecular and Cellular Endocrinology.

[8]  T. Hibi,et al.  MyD88-dependent pathway accelerates the liver damage of Concanavalin A-induced hepatitis. , 2010, Biochemical and biophysical research communications.

[9]  D. Adams,et al.  Mechanisms of immune-mediated liver injury. , 2010, Toxicological Sciences.

[10]  J. Das,et al.  Acetaminophen induced acute liver failure via oxidative stress and JNK activation: Protective role of taurine by the suppression of cytochrome P450 2E1 , 2010, Free radical research.

[11]  P. Muriel Role of free radicals in liver diseases , 2009, Hepatology international.

[12]  Wei Zhang,et al.  Phosphoinositide 3-kinase gamma inhibitor ameliorates concanavalin A-induced hepatic injury in mice. , 2009, Biochemical and biophysical research communications.

[13]  I. Zhari,et al.  Absorption of andrographolides from Andrographis paniculata and its effect on CCl(4)-induced oxidative stress in rats. , 2009, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[14]  Zhengtao Wang,et al.  Intracellular glutathione regulates Andrographolide-induced cytotoxicity on hepatoma Hep3B cells , 2009, Redox report : communications in free radical research.

[15]  G. Mantion,et al.  Effects of Andrographis paniculata extract and Andrographolide on hepatic cytochrome P450 mRNA expression and monooxygenase activities after in vivo administration to rats and in vitro in rat and human hepatocyte cultures. , 2009, Chemico-biological interactions.

[16]  Yi Zhang,et al.  Role of Jhdm2a in regulating metabolic gene expression and obesity resistance , 2009, Nature.

[17]  H. Canatan,et al.  In vitro and in vivo anti-inflammatory effects of andrographolide. , 2009, International immunopharmacology.

[18]  S. Shono,et al.  Superoxide produced by Kupffer cells is an essential effector in concanavalin A–induced hepatitis in mice , 2008, Hepatology.

[19]  M. Sporn,et al.  Genetic or pharmacologic amplification of nrf2 signaling inhibits acute inflammatory liver injury in mice. , 2008, Toxicological sciences : an official journal of the Society of Toxicology.

[20]  A. Görlach,et al.  The cross-talk between NF-kappaB and HIF-1: further evidence for a significant liaison. , 2008, The Biochemical journal.

[21]  Anja Voigt,et al.  Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress. , 2007, Cell metabolism.

[22]  N. Trivedi,et al.  Hepatoprotective Effect of Andrographolide Against Hexachlorocyclohexane-Induced Oxidative Injury , 2007, Integrative cancer therapies.

[23]  H. Cheung,et al.  Andrographolide induces cell cycle arrest at G2/M phase and cell death in HepG2 cells via alteration of reactive oxygen species. , 2007, European journal of pharmacology.

[24]  E. Niki,et al.  S-allyl cysteine prevents CCl4-induced acute liver injury in rats , 2007, Free radical research.

[25]  David S. Park,et al.  Role of cyclooxygenase‐2 induction by transcription factor Sp1 and Sp3 in neuronal oxidative and DNA damage response , 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[26]  X. Lei,et al.  Mice deficient in Cu,Zn-superoxide dismutase are resistant to acetaminophen toxicity. , 2006, The Biochemical journal.

[27]  B. Yeğen,et al.  Beta-glucan ameliorates methotrexate-induced oxidative organ injury via its antioxidant and immunomodulatory effects. , 2006, European journal of pharmacology.

[28]  Zheng-Tao Wang,et al.  Andrographolide inhibits the production of TNF-alpha and interleukin-12 in lipopolysaccharide-stimulated macrophages: role of mitogen-activated protein kinases. , 2006, Biological & pharmaceutical bulletin.

[29]  Y. Tzeng,et al.  Flavonoids and andrographolides from Andrographis paniculata. , 2004, Phytochemistry.

[30]  J. Franklin,et al.  Bax, reactive oxygen, and cytochrome c release in neuronal apoptosis. , 2003, Antioxidants & redox signaling.

[31]  C. Hogaboam,et al.  C-C Chemokine Ligand 2/Monocyte Chemoattractant Protein-1 Directly Inhibits NKT Cell IL-4 Production and Is Hepatoprotective in T Cell-Mediated Hepatitis in the Mouse1 , 2003, The Journal of Immunology.

[32]  A. Di Carlo,et al.  Non-alcoholic fatty liver disease in an area of southern Italy: main clinical, histological, and pathophysiological aspects. , 2001, Journal of hepatology.

[33]  T. Cotter,et al.  Signalling apoptosis: a radical approach , 2001, Redox report : communications in free radical research.

[34]  M. Manns,et al.  Concanavalin A-induced liver injury triggers hepatocyte proliferation. , 1998, The Journal of clinical investigation.

[35]  T. Murakami,et al.  Transcriptional Activation of the Glut1 Gene in Response to Oxidative Stress in L6 Myotubes* , 1997, The Journal of Biological Chemistry.

[36]  C. Herfarth,et al.  Impact of N-acetylcysteine on the hepatic microcirculation after orthotopic liver transplantation. , 1996, Transplantation.

[37]  D. Green,et al.  Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl , 1995, The Journal of experimental medicine.

[38]  C. Smith,et al.  ACTIVATION OF KUPFFER CELLS AND NEUTROPHILS FOR REACTIVE OXYGEN FORMATION IS RESPONSIBLE FOR ENDOTOXIN-ENHANCED LIVER INJURY AFTER HEPATIC ISCHEMIA , 1995, Shock.

[39]  M. Leist,et al.  Concanavalin A—induced T‐cell—mediated hepatic injury in mice: The role of tumor necrosis factor , 1995, Hepatology.

[40]  B. Shukla,et al.  Andrographolide protects rat hepatocytes against paracetamol-induced damage. , 1993, Journal of ethnopharmacology.

[41]  H. Jaeschke,et al.  Superoxide generation by neutrophils and Kupffer cells during in vivo reperfusion after hepatic ischemia in rats , 1992, Journal of leukocyte biology.

[42]  A. Wendel,et al.  A T cell-dependent experimental liver injury in mice inducible by concanavalin A. , 1992, The Journal of clinical investigation.

[43]  Anupam Sharma,et al.  Hepatoprotective activity of andrographolide against galactosamine & paracetamol intoxication in rats. , 1990, The Indian journal of medical research.