Internal hernias are one of the most devastating late, postsurgical complications associated with laparoscopic Roux-en-Y gastric bypass (LRYGB). The objective of this study was to determine whether placement of a bioabsorbable tissue matrix in soft tissue defects after gastric bypass resulted in a lower incidence of internal hernia development. Prospective database was used to identify all patients who underwent LRYGB between January 2002 and January 2016. These patients were then retrospectively reviewed to determine the development of internal hernia. Before 2009, the retro-Roux defect was left open during the primary operation and the defect at the jejunojejunostomy was closed with sutures or staples. Beginning in 2009, all soft tissue internal defects were reinforced with an 8 cm 3 8-cm piece of bioabsorbable matrix. The incidence of subsequent internal hernia development was compared between these two groups: no bioabsorbable matrix versus use of a bioabsorbable matrix. A total of 2771 patients underwent LRYGB during our study period. From these, 1215 procedures were performed without tissue reinforcement and 1556 were performed using a bioabsorbable matrix. During the study period, 274 patients developed an internal hernia. Patients who did not have tissue reinforcement at closure had a significantly higher internal hernia rate [225/1215 (18.5%) vs 49/1556 (3.1%), P < 0.005]. This study demonstrates a statistically significant reduction in internal hernia formation after LRYGB with the addition of a bioabsorbable tissue matrix. Although prospective studies are needed, early evidence suggests that reinforcement with a bioabsorbable tissue scaffold is an effective method for minimizing internal hernias after LRYGB.
[1]
J. Hedenbro,et al.
The mesenteric defects in laparoscopic Roux-en-Y gastric bypass: 5 years follow-up of non-closure versus closure using the stapler technique
,
2017,
Surgical Endoscopy.
[2]
P. Chowbey,et al.
Mesenteric Defect Closure Decreases the Incidence of Internal Hernias Following Laparoscopic Roux-En-Y Gastric Bypass: a Retrospective Cohort Study
,
2016,
Obesity Surgery.
[3]
S. Grundmann,et al.
LOP02: MicroRNA-155 Modulates and Aggravates the Inflammatory Response in Ischemia Reperfusion Injury Following Free Tissue Transfer
,
2012
.
[4]
Nestor de la Cruz-Muñoz,et al.
Closure of mesenteric defect can lead to decrease in internal hernias after Roux-en-Y gastric bypass.
,
2011,
Surgery for Obesity and Related Diseases.
[5]
B. Heniford,et al.
Failure of Mesenteric Defect Closure After Roux-en-Y Gastric Bypass
,
2010,
JSLS : Journal of the Society of Laparoendoscopic Surgeons.
[6]
A. Ahmed,et al.
Bioabsorbable Glycolide Copolymer Staple-Line Reinforcement Decreases Internal Hernia Rate After Laparoscopic Roux-en-Y Gastric Bypass
,
2008,
Obesity surgery.
[7]
K. Higa,et al.
Internal Hernias after Laparoscopic Roux-en-Y Gastric Bypass: Incidence, Treatment and Prevention
,
2003,
Obesity surgery.