Fluorine-19 nuclear magnetic resonance investigation of the noncovalent and covalent binary complexes of 5-fluorodeoxyuridylate and Lactobacillus casei thymidylate synthetase.

[1]  W. A. Munroe,et al.  Effects of polyoxyanions on sulfhydryl group modification of thymidylate synthetase. , 1978, Biochemistry.

[2]  R. B. Dunlap,et al.  The effect of thiols on the sulfhydryl content and nucleotide binding of thymidylate synthetase. , 1978, Biochemical and biophysical research communications.

[3]  R. Byrd,et al.  Elucidation of the detailed structures of the native and denatured ternary complexes of thymidylate synthetase via fluorine-19 NMR , 1978 .

[4]  G. Digenis,et al.  Carbon-13 nuclear magnetic resonance studies of bisulfite-pyrimidine addition reactions: stereoselective formation and reactions of the 5-halouridines , 1978 .

[5]  Y. Wataya,et al.  5-Nitro-2'-deoxyuridylate: a mechanism-based inhibitor of thymidylate synthetase. , 1978, Biochemical and biophysical research communications.

[6]  P. D. Ellis,et al.  19F NMR of the 5-fluorodeoxyuridylate-thymidylate synthetase binary complex. , 1978, Biochemical and biophysical research communications.

[7]  P. Danenberg.  Thymidylate synthetase - a target enzyme in cancer chemotherapy. , 1977, Biochimica et biophysica acta.

[8]  R. Byrd,et al.  FLUORINE-19 NUCLEAR MAGNETIC RESONANCE INVESTIGATION OF THE TERNARY COMPLEX FORMED BETWEEN NATIVE THYMIDYLATE SYNTHETASE, 5-FLUORO-2′-DEOXYURIDYLATE, AND 5,10-METHYLENETETRAHYDROFOLATE , 1977 .

[9]  R. B. Dunlap,et al.  Sulfhydryl group modification of thymidylate synthetase and its effect on activity and ternary complex formation. , 1977, The Journal of biological chemistry.

[10]  R. Byrd,et al.  A multinuclear 18-mm probe for the varian XL-100-15 NMR spectrometer , 1977 .

[11]  R. Kisliuk,et al.  A calorimetric study of the binding of 2'-deoxyuridine-5'-phosphate and 5-fluoro-2'-deoxyuridine-5'-phosphate to thymidylate synthetase. , 1977, Archives of biochemistry and biophysics.

[12]  Y. Wataya,et al.  Thymidylate synthetase: fluorine-19 nmr characterization of the active site peptide covalently bound to 5-fluoro-2'-deoxyuridylate and 5,10-methylenetetrahydrofolate. , 1976, Biochemical and biophysical research communications.

[13]  D. Santi,et al.  Thymidylate synthetase: studies on peptide containing covalently bound 5-fluoro-2'-deoxyuridylate and 5,10-methylenetetrahydrofolate. , 1976, Biochemical and biophysical research communications.

[14]  J. Lyon,et al.  Formation of ternary complexes of thymidylate synthetase as followed by absorbance, fluorescence, and circular dichroic spectra and gel electrophoresis. , 1976, The Journal of biological chemistry.

[15]  G. Maley,et al.  Factors affecting substrate binding in Lactobacillus casei thymidylate synthetase as studied by equilibrium dialysis. , 1976, Biochemistry.

[16]  R. Leary,et al.  Interaction of deoxyuridylate with thymidylate synthetase. , 1975, The Journal of biological chemistry.

[17]  J. Lyon,et al.  Gel electrophoresis as a means of detecting ternary complex formation of thymidylate synthetase , 1974 .

[18]  F. Sedor,et al.  The addition of bisulfite to 5-fluorouracil. Evidence for a change in rate determining step , 1974 .

[19]  D. Santi,et al.  Purification and amino acid analysis of an active site peptide from thymidylate synthetase containing covalently bound 5-fluoro-2'-deoxyuridylate and methylenetetrahydrofolate. , 1974, Biochemical and biophysical research communications.

[20]  C. Heidelberger,et al.  Structures of reversible and irreversible complexes of thymidylate synthetase and fluorinated pyrimidine nucleotides. , 1974, Biochemistry.

[21]  D. Santi,et al.  Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylate. , 1974, Biochemistry.

[22]  C. Heidelberger,et al.  Thymidylate synthetase: mechanism of inhibition by 5-fluoro-2'-deoxyuridylate. , 1972, Biochemical and biophysical research communications.

[23]  E. Sander,et al.  The effect of bisulfite on the dehalogenation of 5-chloro-, 5-bromo-, and 5-iodouracil. , 1972, Archives of biochemistry and biophysics.

[24]  R. J. Cushley,et al.  Reactions of 5-fluorouracil derivatives with sodium deuteroxide☆ , 1968 .