Osteocyte lacunae in transiliac bone biopsy samples across life span.

[1]  R. Recker,et al.  No evidence of mineralization abnormalities in iliac bone of premenopausal women with type 2 diabetes mellitus , 2022, Journal of musculoskeletal & neuronal interactions.

[2]  A. Ural,et al.  Quantifying how altered lacunar morphology and perilacunar tissue properties influence local mechanical environment of osteocyte lacunae using finite element modeling. , 2022, Journal of The Mechanical Behavior of Biomedical Materials.

[3]  R. Müller,et al.  Large-scale osteocyte lacunar morphological analysis of transiliac bone in normal and osteoporotic premenopausal women , 2021, medRxiv.

[4]  A. Najafi,et al.  Computational study of the mechanical influence of lacunae and perilacunar zones in cortical bone microcracking. , 2021, Journal of the mechanical behavior of biomedical materials.

[5]  Peter Zioupos,et al.  Assessing bone maturity: Compositional and mechanical properties of rib cortical bone at different ages. , 2021, Bone.

[6]  X. S. Liu,et al.  Structural role of osteocyte lacunae on mechanical properties of bone matrix: A cohesive finite element study. , 2021, Journal of the mechanical behavior of biomedical materials.

[7]  O. Mäkitie,et al.  Abnormal Bone Tissue Organization and Osteocyte Lacunocanalicular Network in Early‐Onset Osteoporosis Due to SGMS2 Mutations , 2021, JBMR plus.

[8]  R. Müller,et al.  Large-scale quantification of human osteocyte lacunar morphological biomarkers as assessed by ultra-high-resolution desktop micro-computed tomography. , 2021, Bone.

[9]  F. Glorieux,et al.  Increased Osteocyte Lacunae Density in the Hypermineralized Bone Matrix of Children with Osteogenesis Imperfecta Type I , 2021, International journal of molecular sciences.

[10]  P. Fratzl,et al.  Quantitative Backscattered Electron Imaging of Bone Using a Thermionic or a Field Emission Electron Source , 2021, Calcified Tissue International.

[11]  O. Mäkitie,et al.  Bone material properties and response to teriparatide in osteoporosis due to WNT1 and PLS3 mutations. , 2021, Bone.

[12]  P. Fratzl,et al.  The mechanoresponse of bone is closely related to the osteocyte lacunocanalicular network architecture , 2020, Proceedings of the National Academy of Sciences of the United States of America.

[13]  E. Flynn,et al.  Histopathology of osteogenesis imperfecta bone. Supramolecular assessment of cells and matrices in the context of woven and lamellar bone formation using light, polarization and ultrastructural microscopy , 2020, Bone reports.

[14]  M. Burghammer,et al.  Heterogeneity of the osteocyte lacuno-canalicular network architecture and material characteristics across different tissue types in healing bone. , 2020, Journal of structural biology.

[15]  P. Fratzl,et al.  Alterations of bone material properties in adult patients with X-linked hypophosphatemia (XLH). , 2020, Journal of structural biology.

[16]  Huiling Cao,et al.  Molecular mechanosensors in osteocytes , 2020, Bone Research.

[17]  Mark L. Johnson,et al.  Osteocyte lacunar strain determination using multiscale finite element analysis , 2020, Bone reports.

[18]  M. Amling,et al.  Large osteocyte lacunae in iliac crest infantile bone are not associated with impaired mineral distribution or signs of osteocytic osteolysis. , 2020, Bone.

[19]  L. Bonewald,et al.  The Osteocyte: New Insights. , 2020, Annual review of physiology.

[20]  P. Fratzl,et al.  Newly formed and remodeled human bone exhibits differences in the mineralization process. , 2020, Acta biomaterialia.

[21]  P. Fratzl,et al.  Network architecture strongly influences the fluid flow pattern through the lacunocanalicular network in human osteons , 2019, Biomechanics and modeling in mechanobiology.

[22]  F. Shapiro,et al.  Woven bone overview: structural classification based on its integral role in developmental, repair and pathological bone formation throughout vertebrate groups. , 2019, European cells & materials.

[23]  J. Werzowa,et al.  Bone matrix mineralization and osteocyte lacunae characteristics in patients with chronic kidney disease - mineral bone disorder (CKD-MBD) , 2019, Journal of musculoskeletal & neuronal interactions.

[24]  J. Pettifor,et al.  Calcium Deficiency Rickets in African Adolescents: Cortical Bone Histomorphometry , 2019, JBMR plus.

[25]  D. Burr,et al.  Osteocytic perilacunar/canalicular turnover in hemodialysis patients with high and low serum PTH levels. , 2018, Bone.

[26]  M. Djuric,et al.  Inter-site variability of the osteocyte lacunar network in the cortical bone underpins fracture susceptibility of the superolateral femoral neck. , 2018, Bone.

[27]  J. Klein-Nulend,et al.  Mechanical Loading Differentially Affects Osteocytes in Fibulae from Lactating Mice Compared to Osteocytes in Virgin Mice: Possible Role for Lacuna Size , 2018, Calcified Tissue International.

[28]  Arto Koistinen,et al.  Acid-etching technique of non-decalcified bone samples for visualizing osteocyte-lacuno-canalicular network using scanning electron microscope , 2018, Ultrastructural pathology.

[29]  Mary L Bouxsein,et al.  Comparison of non-invasive assessments of strength of the proximal femur. , 2017, Bone.

[30]  R. Recker,et al.  Baseline mineralizing surface determines the magnitude of the bisphosphonate effect on cortical bone mineralization in postmenopausal osteoporotic patients , 2017, Journal of musculoskeletal & neuronal interactions.

[31]  F. Glorieux,et al.  Hypermineralization and High Osteocyte Lacunar Density in Osteogenesis Imperfecta Type V Bone Indicate Exuberant Primary Bone Formation , 2017, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[32]  G. Gruber,et al.  Coalignment of osteocyte canaliculi and collagen fibers in human osteonal bone. , 2017, Journal of structural biology.

[33]  D. Cooper,et al.  Lacunar-canalicular network in femoral cortical bone is reduced in aged women and is predominantly due to a loss of canalicular porosity , 2017, Bone reports.

[34]  R. Mendelsohn,et al.  Lactation‐Induced Changes in the Volume of Osteocyte Lacunar‐Canalicular Space Alter Mechanical Properties in Cortical Bone Tissue , 2017, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[35]  L. Bonewald The Role of the Osteocyte in Bone and Nonbone Disease. , 2017, Endocrinology and metabolism clinics of North America.

[36]  H. Birkedal,et al.  Osteocyte lacunar properties and cortical microstructure in human iliac crest as a function of age and sex. , 2016, Bone.

[37]  A. Agnew,et al.  Intraskeletal variation in human cortical osteocyte lacunar density: Implications for bone quality assessment , 2016, Bone reports.

[38]  R. Recker,et al.  Bone matrix mineralization is preserved during early perimenopausal stage in healthy women: a paired biopsy study , 2016, Osteoporosis International.

[39]  Georg N Duda,et al.  The Periosteal Bone Surface is Less Mechano-Responsive than the Endocortical , 2016, Scientific Reports.

[40]  Georg N Duda,et al.  Long bone maturation is driven by pore closing: A quantitative tomography investigation of structural formation in young C57BL/6 mice. , 2015, Acta Biomaterialia.

[41]  N. Sims,et al.  Quantifying the osteocyte network in the human skeleton. , 2015, Bone.

[42]  R. Ritchie,et al.  Multi-level characterization of human femoral cortices and their underlying osteocyte network reveal trends in quality of young, aged, osteoporotic and antiresorptive-treated bone. , 2015, Biomaterials.

[43]  I. Jasiuk,et al.  Multiscale damage and strength of lamellar bone modeled by cohesive finite elements. , 2013, Journal of the mechanical behavior of biomedical materials.

[44]  Philipp Schneider,et al.  A quantitative framework for the 3D characterization of the osteocyte lacunar system. , 2013, Bone.

[45]  John G. Clement,et al.  Femoral osteocyte lacunar density, volume and morphology in women across the lifespan. , 2013, Journal of structural biology.

[46]  Philip Kollmannsberger,et al.  Architecture of the osteocyte network correlates with bone material quality , 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[47]  S. Weinbaum,et al.  Mechanosensation and transduction in osteocytes. , 2013, Bone.

[48]  J. Wysolmerski Osteocytes remove and replace perilacunar mineral during reproductive cycles. , 2013, Bone.

[49]  Sarah L Dallas,et al.  The osteocyte: an endocrine cell ... and more. , 2013, Endocrine reviews.

[50]  P. Fratzl,et al.  Bone material properties in premenopausal women with idiopathic osteoporosis , 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[51]  Hai Qing,et al.  Demonstration of osteocytic perilacunar/canalicular remodeling in mice during lactation , 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[52]  M. Zarrinkalam,et al.  Changes in osteocyte density correspond with changes in osteoblast and osteoclast activity in an osteoporotic sheep model , 2012, Osteoporosis International.

[53]  N. Fazzalari,et al.  Increased proportion of hypermineralized osteocyte lacunae in osteoporotic and osteoarthritic human trabecular bone: implications for bone remodeling. , 2012, Bone.

[54]  J. Skedros,et al.  Analysis of the Effect of Osteon Diameter on the Potential Relationship of Osteocyte Lacuna Density and Osteon Wall Thickness , 2011, Anatomical record.

[55]  Mary L Bouxsein,et al.  Mechanical Contributions of the Cortical and Trabecular Compartments Contribute to Differences in Age-Related Changes in Vertebral Body Strength in Men and Women Assessed by QCT-Based Finite Element Analysis , 2011, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[56]  Michael Hahn,et al.  Decrease in the osteocyte lacunar density accompanied by hypermineralized lacunar occlusion reveals failure and delay of remodeling in aged human bone , 2010, Aging cell.

[57]  Theo H Smit,et al.  Osteocyte morphology in human tibiae of different bone pathologies with different bone mineral density--is there a role for mechanosensing? , 2009, Bone.

[58]  P. Fratzl,et al.  Bone mineralization density distribution in health and disease. , 2008, Bone.

[59]  L. Bonewald,et al.  Osteocyte messages from a bony tomb. , 2007, Cell metabolism.

[60]  S. Curtiss,et al.  Quantitative regional associations between remodeling, modeling, and osteocyte apoptosis and density in rabbit tibial midshafts. , 2007, Bone.

[61]  K. Bachus,et al.  The influence of collagen fiber orientation and other histocompositional characteristics on the mechanical properties of equine cortical bone , 2006, Journal of Experimental Biology.

[62]  L. Vico,et al.  Differences in Osteocyte Density and Bone Histomorphometry Between Men and Women and Between Healthy and Osteoporotic Subjects , 2005, Calcified Tissue International.

[63]  D. Vashishth,et al.  Sexual dimorphism and age dependence of osteocyte lacunar density for human vertebral cancellous bone. , 2005, The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology.

[64]  C. Hernandez,et al.  Osteocyte density in woven bone. , 2004, Bone.

[65]  D. Rao,et al.  Reduced Iliac Cancellous Osteocyte Density in Patients With Osteoporotic Vertebral Fracture , 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[66]  D Vashishth,et al.  Determination of bone volume by osteocyte population , 2002, The Anatomical record.

[67]  S. Ashrafi,et al.  The Canalicular Structure of Compact Bone in the Rat at Different Ages , 2002, Microscopy and Microanalysis.

[68]  N. Rushton,et al.  Osteocyte Lacunar Occupancy in the Femoral Neck Cortex: An Association with Cortical Remodeling in Hip Fracture Cases and Controls. , 2001, Calcified Tissue International.

[69]  F. Glorieux,et al.  Static and dynamic bone histomorphometry in children with osteogenesis imperfecta. , 2000, Bone.

[70]  D Vashishth,et al.  Decline in osteocyte lacunar density in human cortical bone is associated with accumulation of microcracks with age. , 2000, Bone.

[71]  Lynda F. Bonewald,et al.  Identification and Characterization of a Novel Protein, Periostin, with Restricted Expression to Periosteum and Periodontal Ligament and Increased Expression by Transforming Growth Factor β , 1999 .

[72]  P. Fratzl,et al.  Validation of quantitative backscattered electron imaging for the measurement of mineral density distribution in human bone biopsies. , 1998, Bone.

[73]  Dork Sahagian,et al.  3D particle size distributions from 2D observations : stereology for natural applications , 1998 .

[74]  R Huiskes,et al.  Osteocyte density changes in aging and osteoporosis. , 1996, Bone.

[75]  J. R. Bowen,et al.  Normative data for iliac bone histomorphometry in growing children. , 1992, Bone.

[76]  Friedemann Schrenk,et al.  The scaling of human osteocyte lacuna density with body size and metabolism , 2016 .

[77]  Sheila J. Jones,et al.  The Microscopic Structure of Bone in Normal Children and Patients with Osteogenesis Imperfecta: A Survey Using Backscattered Electron Imaging , 2014, Calcified Tissue International.

[78]  Daniel P Nicolella,et al.  Osteocyte lacunae tissue strain in cortical bone. , 2006, Journal of biomechanics.

[79]  R. Evans,et al.  Osteocyte death and hip fracture , 2005, Calcified Tissue International.

[80]  R. Marcus,et al.  Peak Bone Mass , 2000, Osteoporosis International.

[81]  Y. Benjamini,et al.  Controlling the false discovery rate: a practical and powerful approach to multiple testing , 1995 .

[82]  S. A. Saltikov THE DETERMINATION OF THE SIZE DISTRIBUTION OF PARTICLES IN AN OPAQUE MATERIAL FROM A MEASUREMENT OF THE SIZE DISTRIBUTION OF THEIR SECTIONS , 1967 .