Production of a DPP Activity Gradient in the Early Drosophila Embryo through the Opposing Actions of the SOG and TLD Proteins

[1]  Leslie Dale,et al.  Cleavage of Chordin by Xolloid Metalloprotease Suggests a Role for Proteolytic Processing in the Regulation of Spemann Organizer Activity , 1997, Cell.

[2]  Andrew P. McMahon,et al.  The zebrafish organizer requires chordino , 1997, Nature.

[3]  J. Graff,et al.  Embryonic Patterning: To BMP or Not to BMP, That Is the Question , 1997, Cell.

[4]  B. Biehs,et al.  The Drosophila short gastrulation gene prevents Dpp from autoactivating and suppressing neurogenesis in the neuroectoderm. , 1996, Genes & development.

[5]  B. Hogan,et al.  Failure of ventral body wall closure in mouse embryos lacking a procollagen C-proteinase encoded by Bmp1, a mammalian gene related to Drosophila tolloid. , 1996, Development.

[6]  Karlyne M. Reilly,et al.  Short-Range Signaling by Candidate Morphogens of the TGFβ Family and Evidence for a Relay Mechanism of Induction , 1996, Cell.

[7]  J. Wrana,et al.  The Xenopus Dorsalizing Factor noggin Ventralizes Drosophila Embryos by Preventing DPP from Activating Its Receptor , 1996, Cell.

[8]  R. Harland,et al.  The Spemann Organizer Signal noggin Binds and Inactivates Bone Morphogenetic Protein 4 , 1996, Cell.

[9]  Y. Sasai,et al.  Dorsoventral Patterning in Xenopus: Inhibition of Ventral Signals by Direct Binding of Chordin to BMP-4 , 1996, Cell.

[10]  B. Hogan,et al.  Bone morphogenetic proteins: multifunctional regulators of vertebrate development. , 1996, Genes & development.

[11]  M. Sarras BMP-1 and the astacin family of metalloproteinases: a potential link between the extracellular matrix, growth factors and pattern formation. , 1996, BioEssays : news and reviews in molecular, cellular and developmental biology.

[12]  D. Greenspan,et al.  Characterization of a novel gene product (mammalian tolloid-like) with high sequence similarity to mammalian tolloid/bone morphogenetic protein-1. , 1996, Genomics.

[13]  S. Cohen,et al.  Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing , 1996, Nature.

[14]  A. Sieron,et al.  The C-proteinase that processes procollagens to fibrillar collagens is identical to the protein previously identified as bone morphogenic protein-1. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[15]  G. Struhl,et al.  Direct and Long-Range Action of a DPP Morphogen Gradient , 1996, Cell.

[16]  D. Greenspan,et al.  Bone Morphogenetic Protein-1: The Type I Procollagen C-Proteinase , 1996, Science.

[17]  L. Leong,et al.  Bone morphogenic protein-4. , 1996, The international journal of biochemistry & cell biology.

[18]  D. Kimelman,et al.  Drosophila short gastrulation induces an ectopic axis in Xenopus: evidence for conserved mechanisms of dorsal-ventral patterning. , 1995, Development.

[19]  B. Blumberg,et al.  Disruption of BMP signals in embryonic Xenopus ectoderm leads to direct neural induction. , 1995, Genes & development.

[20]  J. Gurdon,et al.  Direct and continuous assessment by cells of their position in a morphogen gradient , 1995, Nature.

[21]  Yoshiki Sasai,et al.  A conserved system for dorsal-ventral patterning in insects and vertebrates involving sog and chordin , 1995, Nature.

[22]  E. Bier,et al.  Xenopus chordin and Drosophila short gastrulation genes encode homologous proteins functioning in dorsal-ventral axis formation , 1995, Cell.

[23]  G. Lyons,et al.  Bone morphogenetic protein-1 and a mammalian tolloid homologue (mTld) are encoded by alternatively spliced transcripts which are differentially expressed in some tissues. , 1994, The Journal of biological chemistry.

[24]  Y. Sasai,et al.  Xenopus chordin: A novel dorsalizing factor activated by organizer-specific homeobox genes , 1994, Cell.

[25]  M. O’Connor,et al.  Characterization of tolloid-related-1: a BMP-1-like product that is required during larval and pupal stages of Drosophila development. , 1994, Developmental biology.

[26]  J. Emery,et al.  Dorsal-ventral patterning of the Drosophila embryo depends on a putative negative growth factor encoded by the short gastrulation gene. , 1994, Genes & development.

[27]  M. Levine,et al.  The screw gene encodes a ubiquitously expressed member of the TGF-beta family required for specification of dorsal cell fates in the Drosophila embryo. , 1994, Genes & development.

[28]  N. Ueno,et al.  A truncated bone morphogenetic protein receptor affects dorsal-ventral patterning in the early Xenopus embryo. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[29]  J. Graff,et al.  Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo , 1994, Cell.

[30]  J. Marsh,et al.  Dorsal midline fate in Drosophila embryos requires twisted gastrulation, a gene encoding a secreted protein related to human connective tissue growth factor. , 1994, Genes & development.

[31]  R. W. Padgett,et al.  Mutational analysis of the Drosophila tolloid gene, a human BMP-1 homolog. , 1994, Development.

[32]  M. O’Connor,et al.  Two domains of the tolloid protein contribute to its unusual genetic interaction with decapentaplegic. , 1994, Developmental biology.

[33]  C. Rushlow,et al.  The Drosophila dorsal morphogen represses the tolloid gene by interacting with a silencer element , 1994, Molecular and cellular biology.

[34]  J. Faber,et al.  Normal table of Xenopus laevis. , 1994 .

[35]  L. Cherbas,et al.  Transformation techniques for Drosophila cell lines. , 1994, Methods in cell biology.

[36]  N. Perrimon,et al.  Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. , 1993, Development.

[37]  W. Gelbart,et al.  An activity gradient of decapentaplegic is necessary for the specification of dorsal pattern elements in the Drosophila embryo. , 1993, Development.

[38]  J. Smith,et al.  Responses of embryonic xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm , 1992, Cell.

[39]  K. Anderson,et al.  decapentaplegic acts as a morphogen to organize dorsal-ventral pattern in the Drosophila embryo , 1992, Cell.

[40]  C. Nüsslein-Volhard,et al.  Altered mitotic domains reveal fate map changes in Drosophila embryos mutant for zygotic dorsoventral patterning genes. , 1992, Development.

[41]  K. Anderson,et al.  Localized enhancement and repression of the activity of the TGF-beta family member, decapentaplegic, is necessary for dorsal-ventral pattern formation in the Drosophila embryo. , 1992, Development.

[42]  F. Hoffmann Transforming growth factor-beta-related genes in Drosophila and vertebrate development. , 1991, Current opinion in cell biology.

[43]  R. Beynon,et al.  The astacin family of metalloendopeptidases , 1991, The Journal of biological chemistry.

[44]  M. O’Connor,et al.  The Drosophila dorsal-ventral patterning gene tolloid is related to human bone morphogenetic protein 1 , 1991, Cell.

[45]  C. Nüsslein-Volhard,et al.  The control of cell fate along the dorsal-ventral axis of the Drosophila embryo. , 1991, Development.

[46]  Ruth Lehmann,et al.  The Drosophila posterior-group gene nanos functions by repressing hunchback activity , 1989, Nature.

[47]  W. Gelbart The decapentaplegic gene: a TGF-beta homologue controlling pattern formation in Drosophila. , 1989, Development.

[48]  V. Rosen,et al.  Novel regulators of bone formation: molecular clones and activities. , 1988, Science.

[49]  E. Wieschaus,et al.  short gastrulation, a mutation causing delays in stage-specific cell shape changes during gastrulation in Drosophila melanogaster. , 1988, Developmental biology.

[50]  C. Nüsslein-Volhard,et al.  The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner , 1988, Cell.

[51]  L. Goldstein,et al.  Characterization and use of the Drosophila metallothionein promoter in cultured Drosophila melanogaster cells. , 1988, Nucleic acids research.

[52]  J. Faber,et al.  Normal Table of Xenopus Laevis (Daudin) , 1958 .