Faster optimal algorithms for segment minimization with small maximal value

The segment minimization problem consists of finding the smallest set of integer matrices (segments) that sum to a given intensity matrix, such that each summand has only one non-zero value (the segment-value), and the nonzeroes in each row are consecutive. This has direct applications in intensity-modulated radiation therapy, an effective form of cancer treatment. We study here the special case when the largest value H in the intensity matrix is small. We show that for an intensity matrix with one row, this problem is fixed-parameter tractable (FPT) in H; our algorithm obtains a significant asymptotic speedup over the previous best FPT algorithm. We also show how to solve the full-matrix problem faster than all previously known algorithms. Finally, we address a closely related problem that deals with minimizing the number of segments subject to a minimum beam-on-time, defined as the sum of the segmentvalues. Here, we obtain an almost-quadratic speedup.

[1]  Gerhard J. Woeginger,et al.  Decomposition of integer matrices and multileaf collimator sequencing , 2005, Discret. Appl. Math..

[2]  Peter J. Stuckey,et al.  Minimum Cardinality Matrix Decomposition into Consecutive-Ones Matrices: CP and IP Approaches , 2007, CPAIOR.

[3]  C. Cotrutz,et al.  Segment-based dose optimization using a genetic algorithm. , 2003, Physics in medicine and biology.

[4]  Sebastian Brand The sum-of-increments constraint in the consecutive-ones matrix decomposition problem , 2009, SAC '09.

[5]  Maxwell Young,et al.  Approximation algorithms for minimizing segments in radiation therapy , 2007, Inf. Process. Lett..

[6]  Konrad Engel,et al.  A new algorithm for optimal multileaf collimator field segmentation , 2005, Discret. Appl. Math..

[7]  Baruch Schieber,et al.  Minimizing Setup and Beam-On Times in Radiation Therapy , 2006, APPROX-RANDOM.

[8]  Natashia Boland,et al.  Mixed integer programming approaches to exact minimization of total treatment time in cancer radiotherapy using multileaf collimators , 2009, Comput. Oper. Res..

[9]  Stephane Durocher,et al.  Faster optimal algorithms for segment minimization with small maximal value , 2013, Discret. Appl. Math..

[10]  Xiaobo Sharon Hu,et al.  Generalized Geometric Approaches for Leaf Sequencing Problems in Radiation Therapy , 2006, Int. J. Comput. Geom. Appl..

[11]  Barry O'Sullivan,et al.  A Shortest Path-Based Approach to the Multileaf Collimator Sequencing Problem , 2009, CPAIOR.

[12]  Xiaobo Sharon Hu,et al.  Generalized Geometric Approaches for Leaf Sequencing Problems in Radiation Therapy , 2005, ISAAC.

[13]  W. Pribitkin Simple upper bounds for partition functions , 2009 .

[14]  R. Siochi,et al.  Minimizing static intensity modulation delivery time using an intensity solid paradigm. , 1999, International journal of radiation oncology, biology, physics.

[15]  P. Xia,et al.  Multileaf collimator leaf sequencing algorithm for intensity modulated beams with multiple static segments. , 1998, Medical physics.

[16]  Thomas Kalinowski The complexity of minimizing the number of shape matrices subject to minimal beam-on time in multileaf collimator field decomposition with bounded fluence , 2009, Discret. Appl. Math..

[17]  Stephane Durocher,et al.  A note on improving the performance of approximation algorithms for radiation therapy , 2011, Information Processing Letters.

[18]  Maxwell Young,et al.  Nonnegative integral subset representations of integer sets , 2007, Inf. Process. Lett..

[19]  F. Frances Yao,et al.  Computational Geometry , 1991, Handbook of Theoretical Computer Science, Volume A: Algorithms and Complexity.