论文信息 - Progressive Scleral Necrosis following I-125 Plaque Radiotherapy for Ciliochoroidal Melanoma with Protruding Extraocular Mass

Progressive Scleral Necrosis following I-125 Plaque Radiotherapy for Ciliochoroidal Melanoma with Protruding Extraocular Mass

Purpose: The aim of this study was to describe the side effects of I-125 brachytherapy in the treatment of uveal melanoma. Methods: This study was conducted as a case report. Results: We report a case of scleral necrosis and protruding episcleral mass following the treatment of uveal melanoma with I-125 brachytherapy. Conclusions: Scleral necrosis after plaque radiotherapy can clinically simulate tumor recurrence with extraocular extension. The management of uveal melanoma requires a careful clinical follow-up, weighing the implications of treatment morbidity and mortality.

Z. Corrêa | Jordan R. Hill

[1] C. Shields,et al. Scleral necrosis after plaque radiotherapy of uveal melanoma: a case-control study. , 2013, Ophthalmology.

[2] L. Desjardins,et al. Scleral necrosis after radiation therapy for uveal melanomas: report of 23 cases , 2008, Graefe's Archive for Clinical and Experimental Ophthalmology.

[3] R. Eagle,et al. Early-onset scleral necrosis after iodine I 125 plaque radiotherapy for ciliochoroidal melanoma. , 1999, Archives of ophthalmology.

[4] R. Eaglejr. The COMS randomized trial of iodine 125 brachytherapy for choroidal melanoma: V. Twelve-year mortality rates and prognostic factors: COMS report No. 28. , 2006, Archives of ophthalmology.