Catalyst-Free Chemoselective Reduction of Nitroarenes Using Thiourea as a Hydrogen Source

A newly developed protocol for the reduction of nitroarenes using thiourea as the hydrogen source is described. The method is simple, inexpensive and easily applicable to the preparation of a variety of substituted anilines with high yields and selectivity. In contrast to traditional hydrogenation methods, this chemistry does not require a catalyst, elaborated work-up procedures, or the use of high-pressure equipment.

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