APOEε4 impacts up-regulation of brain-derived neurotrophic factor after a six-month stretch and aerobic exercise intervention in mild cognitively impaired elderly African Americans: A pilot study

[1]  P. Nilsson,et al.  Pre-diabetes and diabetes are independently associated with adverse cognitive test results: a cross-sectional, population-based study , 2018, BMC Endocrine Disorders.

[2]  P. Chivers,et al.  Identification of genetic markers for skill and athleticism in sub-elite Australian football players: a pilot study. , 2016, The Journal of sports medicine and physical fitness.

[3]  A. Haley,et al.  Serum Brain-Derived Neurotrophic Factor Mediates the Relationship between Abdominal Adiposity and Executive Function in Middle Age , 2016, Journal of the International Neuropsychological Society.

[4]  H. Khalil,et al.  Relationship of circulatory BDNF with cognitive deficits in people with Parkinson's disease , 2016, Journal of the Neurological Sciences.

[5]  M. Vilar,et al.  Regulation of Neurogenesis by Neurotrophins during Adulthood: Expected and Unexpected Roles , 2016, Front. Neurosci..

[6]  D. Bredesen,et al.  Direct Transcriptional Effects of Apolipoprotein E , 2016, The Journal of Neuroscience.

[7]  O. Mors,et al.  Increased serum levels of sortilin are associated with depression and correlated with BDNF and VEGF , 2015, Translational Psychiatry.

[8]  J. Kwagyan,et al.  Culturally Competent Strategies for Recruitment and Retention of African American Populations into Clinical Trials , 2015, Clinical and translational science.

[9]  C. Caltagirone,et al.  Brain-derived neurotrophic factor serum levels correlate with cognitive performance in Parkinson’s disease patients with mild cognitive impairment , 2015, Front. Behav. Neurosci..

[10]  Rong Zhang,et al.  Females have a blunted cardiovascular response to one year of intensive supervised endurance training. , 2015, Journal of applied physiology.

[11]  Simin Liu,et al.  Effects of Exercise Training on Cardiorespiratory Fitness and Biomarkers of Cardiometabolic Health: A Systematic Review and Meta-Analysis of Randomized Controlled Trials , 2015, Journal of the American Heart Association.

[12]  D. Alkon,et al.  ApoE4 and Aβ Oligomers Reduce BDNF Expression via HDAC Nuclear Translocation , 2015, The Journal of Neuroscience.

[13]  R. Meeusen,et al.  Brain-derived neurotrophic factor as a driving force behind neuroplasticity in neuropathic and central sensitization pain: a new therapeutic target? , 2015, Expert opinion on therapeutic targets.

[14]  Juan Zhang,et al.  Cholesterol metabolism and homeostasis in the brain , 2015, Protein & Cell.

[15]  J. Zavadil,et al.  Withdrawal of BDNF from hippocampal cultures leads to changes in genes involved in synaptic function , 2015, Developmental neurobiology.

[16]  Yumei Li,et al.  Combining serum and urine biomarkers in the early diagnosis of mild cognitive impairment that evolves into Alzheimer’s disease in patients with the apolipoprotein E ε4 genotype , 2015, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.

[17]  Wook Song,et al.  Increase of circulating BDNF levels and its relation to improvement of physical fitness following 12 weeks of combined exercise in chronic patients with schizophrenia: A pilot study , 2014, Psychiatry Research.

[18]  S. Duan,et al.  Elevation of Peripheral BDNF Promoter Methylation Links to the Risk of Alzheimer's Disease , 2014, PloS one.

[19]  Mary F. Lopez,et al.  The role of apolipoprotein E in neurodegeneration and cardiovascular disease , 2014, Expert review of proteomics.

[20]  A. Damirchi,et al.  Long term habitual exercise is associated with lower resting level of serum BDNF , 2014, Neuroscience Letters.

[21]  D. Bennett,et al.  Alzheimer's disease in African Americans: risk factors and challenges for the future. , 2014, Health affairs.

[22]  C. Rosano,et al.  The Associations between Serum Brain-Derived Neurotrophic Factor, Potential Confounders, and Cognitive Decline: A Longitudinal Study , 2014, PloS one.

[23]  S. Ohgi,et al.  Changes in serum BDNF levels associated with moderate-intensity exercise in healthy young Japanese men , 2013, SpringerPlus.

[24]  M. Schmolesky,et al.  The effects of aerobic exercise intensity and duration on levels of brain-derived neurotrophic factor in healthy men. , 2013, Journal of sports science & medicine.

[25]  R. Nussbaum Genome-wide association studies, Alzheimer disease, and understudied populations. , 2013, JAMA.

[26]  Huaxi Xu,et al.  Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy , 2013, Nature Reviews Neurology.

[27]  Jasper A. J. Smits,et al.  The Effect of Exercise Training Modality on Serum Brain Derived Neurotrophic Factor Levels in Individuals with Type 2 Diabetes , 2012, PloS one.

[28]  M. Mattson,et al.  Annals of the New York Academy of Sciences Brain-derived Neurotrophic Factor as a Regulator of Systemic and Brain Energy Metabolism and Cardiovascular Health , 2022 .

[29]  L. Ferrucci,et al.  Plasma BDNF Is Associated with Age-Related White Matter Atrophy but Not with Cognitive Function in Older, Non-Demented Adults , 2012, PloS one.

[30]  Shane M. O'Mara,et al.  Aerobic exercise improves hippocampal function and increases BDNF in the serum of young adult males , 2011, Physiology & Behavior.

[31]  Y. Shaham,et al.  Running is the neurogenic and neurotrophic stimulus in environmental enrichment. , 2011, Learning & memory.

[32]  N. Ejiogu,et al.  Recruitment and Retention Strategies for Minority or Poor Clinical Research Participants: Lessons From the Healthy Aging in Neighborhoods of Diversity Across the Life Span Study , 2011, The Gerontologist.

[33]  G. Knudsen,et al.  Blood BDNF concentrations reflect brain-tissue BDNF levels across species. , 2011, The international journal of neuropsychopharmacology.

[34]  D. Holtzman,et al.  Apolipoprotein E in Alzheimer's disease and other neurological disorders , 2011, The Lancet Neurology.

[35]  G. Fan,et al.  Exercise impacts brain‐derived neurotrophic factor plasticity by engaging mechanisms of epigenetic regulation , 2011, The European journal of neuroscience.

[36]  E. McAuley,et al.  Exercise training increases size of hippocampus and improves memory , 2011, Proceedings of the National Academy of Sciences.

[37]  Jerome D. Thayer,et al.  Trends in Body Fat, Body Mass Index and Physical Fitness Among Male and Female College Students , 2010, Nutrients.

[38]  H. Nasrallah,et al.  Decreased BDNF levels in CSF of drug-naive first-episode psychotic subjects: correlation with plasma BDNF and psychopathology. , 2010, The international journal of neuropsychopharmacology.

[39]  E. McAuley,et al.  Brain-Derived Neurotrophic Factor Is Associated with Age-Related Decline in Hippocampal Volume , 2010, The Journal of Neuroscience.

[40]  N. Secher,et al.  Endurance training enhances BDNF release from the human brain. , 2010, American journal of physiology. Regulatory, integrative and comparative physiology.

[41]  K. Langa,et al.  Cognitive performance and informant reports in the diagnosis of cognitive impairment and dementia in African Americans and whites , 2009, Alzheimer's & Dementia.

[42]  A. Sartorius,et al.  Correlations and Discrepancies between Serum and Brain Tissue Levels of Neurotrophins after Electroconvulsive Treatment in Rats , 2009, Pharmacopsychiatry.

[43]  M. Mattson,et al.  Voluntary exercise and caloric restriction enhance hippocampal dendritic spine density and BDNF levels in diabetic mice , 2009, Hippocampus.

[44]  Carl W. Cotman,et al.  Exercise improves cognition and hippocampal plasticity in APOE ε4 mice , 2009, Alzheimer's & Dementia.

[45]  O. Gureje,et al.  Prevalence rates for dementia and Alzheimer's disease in African Americans: 1992 versus 2001 , 2009, Alzheimer's & Dementia.

[46]  H. Danker-Hopfe,et al.  Serum neurotrophins—A study on the time course and influencing factors in a large old age sample , 2007, Neurobiology of Aging.

[47]  Tamara Aid,et al.  Dissecting the human BDNF locus: Bidirectional transcription, complex splicing, and multiple promoters☆ , 2007, Genomics.

[48]  James S. Williams,et al.  The effect of acute exercise on serum brain-derived neurotrophic factor levels and cognitive function. , 2007, Medicine and science in sports and exercise.

[49]  N. Maeda,et al.  Apolipoprotein E4 in Macrophages Enhances Atherogenesis in a Low Density Lipoprotein Receptor-dependent Manner* , 2007, Journal of Biological Chemistry.

[50]  Kaia Palm,et al.  Mouse and rat BDNF gene structure and expression revisited , 2006, Journal of neuroscience research.

[51]  Paige E. Scalf,et al.  Aerobic exercise training increases brain volume in aging humans. , 2006, The journals of gerontology. Series A, Biological sciences and medical sciences.

[52]  J. Virchow,et al.  Maternal serum concentrations of BDNF and depression in the perinatal period , 2006, Psychoneuroendocrinology.

[53]  Zhe Ying,et al.  Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition , 2004, The European journal of neuroscience.

[54]  R. Petersen Mild cognitive impairment as a diagnostic entity , 2004, Journal of internal medicine.

[55]  P. Thompson,et al.  Apolipoprotein E genotype and changes in serum lipids and maximal oxygen uptake with exercise training. , 2004, Metabolism: clinical and experimental.

[56]  Roland R Roy,et al.  Voluntary exercise induces a BDNF-mediated mechanism that promotes neuroplasticity. , 2002, Journal of neurophysiology.

[57]  C. Cotman,et al.  Estrogen and exercise interact to regulate brain‐derived neurotrophic factor mRNA and protein expression in the hippocampus , 2001, The European journal of neuroscience.

[58]  R. D. White,et al.  Performing the exercise test. , 2001, Primary care.

[59]  R. Holsinger,et al.  Quantitation of BDNF mRNA in human parietal cortex by competitive reverse transcription-polymerase chain reaction: decreased levels in Alzheimer's disease. , 2000, Brain research. Molecular brain research.

[60]  R. Mayeux,et al.  Rates of dementia in three ethnoracial groups , 1999, International journal of geriatric psychiatry.

[61]  William A Banks,et al.  Transport of brain-derived neurotrophic factor across the blood–brain barrier , 1998, Neuropharmacology.

[62]  Carol Ewing Garber,et al.  ACSM Position Stand: The Recommended Quantity and Quality of Exercise for Developing and Maintaining Cardiorespiratory and Muscular Fitness, and Flexibility in Healthy Adults , 1998 .

[63]  Peter R. Cavanagh,et al.  Exercise and physical activity for older adults , 1998 .

[64]  I. Takeuchi,et al.  Distribution of Brain‐Derived Neurotrophic Factor in Rats and Its Changes with Development in the Brain , 1997, Journal of neurochemistry.

[65]  C. Cotman,et al.  Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain , 1996, Brain Research.

[66]  B. Reed,et al.  Age and education correction of Mini-Mental State Examination for English- and Spanish-speaking elderly , 1996, Neurology.

[67]  John O. Holloszy,et al.  Effects of Aging, Sex, and Physical Training on Cardiovascular Responses to Exercise , 1992, Circulation.

[68]  Y. Barde,et al.  Regional distribution of brain‐derived neurotrophic factor mRNA in the adult mouse brain. , 1990, The EMBO journal.

[69]  R. Bruce,et al.  Exercise stress testing in evaluation of patients with ischemic heart disease. , 1969, Progress in cardiovascular diseases.

[70]  N. Doba,et al.  Experimental Gerontology , 2022 .

[71]  S. Gielen,et al.  Exercise training in patients with heart disease: review of beneficial effects and clinical recommendations. , 2015, Progress in cardiovascular diseases.

[72]  O. Forlenza,et al.  Decreased Neurotrophic Support is Associated with Cognitive Decline in Non-Demented Subjects. , 2015, Journal of Alzheimer's disease : JAD.

[73]  Flávia Gomes de Melo Coelho,et al.  Acute aerobic exercise increases brain-derived neurotrophic factor levels in elderly with Alzheimer's disease. , 2014, Journal of Alzheimer's disease : JAD.

[74]  Huadong Zhou,et al.  Associations Between ApoEε4 Carrier Status and Serum BDNF Levels—New Insights into the Molecular Mechanism of ApoEε4 Actions in Alzheimer’s Disease , 2014, Molecular Neurobiology.

[75]  Sudha Seshadri,et al.  Serum brain-derived neurotrophic factor and the risk for dementia: the Framingham Heart Study. , 2014, JAMA neurology.

[76]  E. Masliah,et al.  Apathy and APOE4 are associated with reduced BDNF levels in Alzheimer's disease. , 2014, Journal of Alzheimer's disease : JAD.

[77]  Glen E Duncan,et al.  Effects of aerobic exercise on mild cognitive impairment: a controlled trial. , 2010, Archives of neurology.

[78]  S. Waring,et al.  Brain-derived neurotrophic factor levels in Alzheimer's disease. , 2009, Journal of Alzheimer's disease : JAD.

[79]  A. Kramer,et al.  Be smart, exercise your heart: exercise effects on brain and cognition , 2008, Nature Reviews Neuroscience.

[80]  L. White,et al.  Exercise and Brain Health — Implications for Multiple Sclerosis , 2008, Sports medicine.