Efficient inhibition of HIV-1 replication by an artificial polycistronic miRNA construct

[1]  Jiahuai Han,et al.  Efficient inhibition of HIV-1 replication by an artificial polycistronic miRNA construct , 2012, Virology Journal.

[2]  Guofeng Zhang,et al.  Effective inhibition of foot-and-mouth disease virus (FMDV) replication in vitro by vector-delivered microRNAs targeting the 3D gene , 2011, Virology Journal.

[3]  S. Hassan,et al.  Effect of combined siRNA of HCV E2 gene and HCV receptors against HCV , 2011, Virology Journal.

[4]  S. Riazuddin,et al.  Inhibition of full length Hepatitis C Virus particles of 1a genotype through small interference RNA , 2011, Virology Journal.

[5]  Sheena M Saayman,et al.  Effective Pol III-expressed long hairpin RNAs targeted to multiple unique sites of HIV-1. , 2010, Methods in molecular biology.

[6]  J. Nolta,et al.  Preintegration HIV-1 inhibition by a combination lentiviral vector containing a chimeric TRIM5 alpha protein, a CCR5 shRNA, and a TAR decoy. , 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

[7]  N. Israsena,et al.  Inhibition of rabies virus replication by multiple artificial microRNAs. , 2009, Antiviral research.

[8]  Hiroyuki Tagawa,et al.  MicroRNA-17-92 down-regulates expression of distinct targets in different B-cell lymphoma subtypes. , 2008, Blood.

[9]  B. Berkhout,et al.  Evaluation of safety and efficacy of RNAi against HIV-1 in the human immune system (Rag-2-/-γc-/-) mouse model , 2009, Gene Therapy.

[10]  I. Hirono,et al.  Engineered virus-encoded pre-microRNA (pre-miRNA) induces sequence-specific antiviral response in addition to nonspecific immunity in a fish cell line: convergence of RNAi-related pathways and IFN-related pathways in antiviral response. , 2008, Antiviral research.

[11]  C. Croce,et al.  Emerging role of miR-106b-25/miR-17-92 clusters in the control of transforming growth factor beta signaling. , 2008, Cancer research.

[12]  P. Uchil,et al.  Effective suppression of HIV-1 by artificial bispecific miRNA targeting conserved sequences with tolerance for wobble base-pairing. , 2008, Biochemical and biophysical research communications.

[13]  M. Amarzguioui,et al.  Engineering and optimization of the mir-106b-cluster for ectopic expression of multiplexed anti-HIV RNAs , 2008, Gene Therapy.

[14]  K. Morris,et al.  The Efficacy of Generating Three Independent Anti-HIV-1 siRNAs from a Single U6 RNA Pol III-Expressed Long Hairpin RNA , 2008, PloS one.

[15]  B. Berkhout,et al.  Inhibition of HIV-1 by multiple siRNAs expressed from a single microRNA polycistron , 2008, Nucleic acids research.

[16]  Ben Berkhout,et al.  Lentiviral Vector Design for Multiple shRNA Expression and Durable HIV-1 Inhibition , 2008, Molecular Therapy.

[17]  John J Rossi,et al.  Genetic therapies against HIV , 2007, Nature Biotechnology.

[18]  Tammy Chang,et al.  Inhibition of HIV-1 replication with designed miRNAs expressed from RNA polymerase II promoters , 2007, Gene Therapy.

[19]  C. Wychowski,et al.  Inhibition of Hepatitis C Virus Infection in Cell Culture by Small Interfering RNAs , 2007, Molecular Therapy.

[20]  Xiaodong Wang,et al.  Biochemical mechanisms of the RNA-induced silencing complex , 2007, Cell Research.

[21]  Fangjun Jia,et al.  Stable inhibition of hepatitis B virus expression and replication in HepG2.2.15 cells by RNA interference based on retrovirus delivery. , 2007, Journal of biotechnology.

[22]  F Xiao-Feng Qin,et al.  Optimization and functional effects of stable short hairpin RNA expression in primary human lymphocytes via lentiviral vectors. , 2006, Molecular therapy : the journal of the American Society of Gene Therapy.

[23]  Theresa A. Storm,et al.  Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways , 2006, Nature.

[24]  S. Elledge,et al.  A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[25]  R. Shiekhattar,et al.  TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing , 2005, Nature.

[26]  Hanah Margalit,et al.  Clustering and conservation patterns of human microRNAs , 2005, Nucleic acids research.

[27]  V. Kim.  MicroRNA biogenesis: coordinated cropping and dicing , 2005, Nature Reviews Molecular Cell Biology.

[28]  Ben Berkhout,et al.  HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome , 2005, Nucleic acids research.

[29]  Hong Yang,et al.  Inhibition of respiratory syncytial virus infection with intranasal siRNA nanoparticles targeting the viral NS1 gene , 2005, Nature Medicine.

[30]  B. Cullen.  Transcription and processing of human microRNA precursors. , 2004, Molecular cell.

[31]  V. Kim,et al.  The Drosha-DGCR8 complex in primary microRNA processing. , 2004, Genes & development.

[32]  B. Cullen,et al.  Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. , 2004, RNA.

[33]  Sanghyuk Lee,et al.  MicroRNA genes are transcribed by RNA polymerase II , 2004, The EMBO journal.

[34]  T. Tuschl,et al.  Mechanisms of gene silencing by double-stranded RNA , 2004, Nature.

[35]  T. Tumpey,et al.  Protection against lethal influenza virus challenge by RNA interference in vivo. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[36]  Ben Berkhout,et al.  Human Immunodeficiency Virus Type 1 Escapes from RNA Interference-Mediated Inhibition , 2004, Journal of Virology.

[37]  B. Cullen,et al.  Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. , 2003, Genes & development.

[38]  B. Ramratnam,et al.  Human Immunodeficiency Virus Type 1 Escape from RNA Interference , 2003, Journal of Virology.

[39]  V. Kim,et al.  The nuclear RNase III Drosha initiates microRNA processing , 2003, Nature.

[40]  A. Fire,et al.  Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans , 1998, Nature.

[41]  G. Veres,et al.  Intracellular expression of RNA transcripts complementary to the human immunodeficiency virus type 1 gag gene inhibits viral replication in human CD4+ lymphocytes , 1996, Journal of virology.

[42]  M. Emerman,et al.  Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated beta-galactosidase gene , 1992, Journal of virology.