Nucleosides and nucleotides. 176. 2'-Deoxy-2'-hydroxylaminocytidine: a new antitumor nucleoside that inhibits DNA synthesis although it has a ribonucleoside structure.
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S. Shuto | A. Matsuda | O. Inanami | M. Kuwabara | A. Ogawa | M. Tanaka | T. Sasaki
[1] Y. Endo,et al. Anti-tumor mechanisms of 3'-ethynyluridine and 3'-ethynylcytidine as RNA synthesis inhibitors: development and characterization of 3'-ethynyluridine-resistant cells. , 1997, Cancer letters.
[2] M. Fukushima,et al. Nucleosides and Nucleotides. 158. 1-(3-C-Ethynyl-β-d-ribo-pentofuranosyl)- cytosine, 1-(3-C-Ethynyl-β-d-ribo-pentofuranosyl)uracil, and Their Nucleobase Analogues as New Potential Multifunctional Antitumor Nucleosides with a Broad Spectrum of Activity1 , 1996 .
[3] W. Pieken,et al. 2'-DEOXY-2'-ALKOXYLAMINOURIDINES : NOVEL 2'-SUBSTITUTED URIDINES PREPARED BY INTRAMOLECULAR NUCLEOPHILIC RING OPENING OF 2,2'-O-ANHYDROURIDINES , 1996 .
[4] M. Fukushima,et al. Antitumor effect of a novel multifunctional antitumor nucleoside, 3'-ethynylcytidine, on human cancers. , 1996, Oncology reports.
[5] A. Matsuda,et al. Nucleosides and nucleotides. 152. 1-(3-C-Ethynyl-β-D-ribo-pentofuranosyl)uracil as a broad spectrum antitumor nucleoside , 1996 .
[6] A. Matsuda,et al. Nucleosides and nucleotides. 141. Chemical stability of a new antitumor nucleoside, 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine in alkaline medium: formation of 2'-C-cyano-2'-deoxy-1-beta-D-ribo-pentofuranosylcytosine and its antitumor activity. , 1995, Journal of medicinal chemistry.
[7] V. Heinemann,et al. Gemcitabine: metabolism, mechanisms of action, and self-potentiation. , 1995, Seminars in oncology.
[8] A. Matsuda,et al. 2′-C-Cyano-2′-deoxy-1-β-D-arabinofuranosylcytosine (CNDAC): A Mechanism-Based DNA-Strand-Breaking Antitumor Nucleoside1 , 1995 .
[9] I. Komáromi,et al. Anti-HIV Derivatives of 1-(2,3-Dideoxy-3-N-hydroxyamino-β-D-threo-pentofuranosyl)thymine , 1994 .
[10] A. Bitonti,et al. Regression of human breast tumor xenografts in response to (E)-2'-deoxy-2'-(fluoromethylene)cytidine, an inhibitor of ribonucleoside diphosphate reductase. , 1994, Cancer research.
[11] N. Minakawa,et al. Nucleosides and nucleotides. 122. 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosylcytosine and its derivatives. A new class of nucleoside with a broad antitumor spectrum. , 1993, Journal of medicinal chemistry.
[12] K. Čapek,et al. Synthesis and anti-HIV activity of 3′-deoxy-3′-(N-hydroxyamino) analogues of nucleosides , 1992 .
[13] A. Matsuda,et al. Antitumor activity of a novel nucleoside, 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosylcytosine (CNDAC) against murine and human tumors. , 1992, Cancer letters.
[14] A. Matsuda,et al. Nucleosides and Nucleotides. 106. Synthesis and Biological Activity of 1-(2-Deoxy-2-hydroxyimino- or Methoxyimino-β-D-erythro-pentofuranosyl)-thymine and -Cytosine§,1 , 1992 .
[15] Y. Cheng,et al. Synthesis and anticancer and antiviral activities of various 2'- and 3'-methylidene-substituted nucleoside analogues and crystal structure of 2'-deoxy-2'-methylidenecytidine hydrochloride. , 1991, Journal of medicinal chemistry.
[16] J. Bollinger,et al. 2'-Deoxy-2'-methylenecytidine and 2'-deoxy-2',2'-difluorocytidine 5'-diphosphates: potent mechanism-based inhibitors of ribonucleotide reductase. , 1991, Journal of medicinal chemistry.
[17] A. Matsuda,et al. Antitumor activity of 2'-deoxy-2'-methylidenecytidine, a new 2'-deoxycytidine derivative. , 1991, Cancer research.
[18] A. Matsuda,et al. Nucleosides and nucleotides. 97. Synthesis of new broad spectrum antineoplastic nucleosides, 2'-deoxy-2'-methylidenecytidine (DMDC) and its derivatives. , 1991, Journal of medicinal chemistry.
[19] G. Bernardinelli,et al. Novel types of cyclonucleosides , 1990 .
[20] J. G. Cory,et al. Inhibitors of Ribonucleoside Diphosphate Reductase Activity , 1989 .
[21] J. Tronchet,et al. 3′-Deoxy-3′-Hydroxyamino-β-D-Xylofuranosyluracil and Derivatives Thereof , 1988 .
[22] James B. Mitchell,et al. Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing. , 1987, Cancer research.
[23] E. Moore,et al. The inhibition of ribonucleoside diphosphate reductase by hydroxyurea, guanazole and pyrazoloimidazole (IMPY). , 1985, Pharmacology & therapeutics.
[24] G. Weber. Biochemical strategy of cancer cells and the design of chemotherapy: G. H. A. Clowes Memorial Lecture. , 1983, Cancer research.
[25] E. Hayon,et al. Intermediated produced from the one-electron oxidation and reduction of hydroxylamines. Acid-base properties of the amino, hydroxyamino, and methoxyamino radicals , 1971 .