Nucleosides and nucleotides. 176. 2'-Deoxy-2'-hydroxylaminocytidine: a new antitumor nucleoside that inhibits DNA synthesis although it has a ribonucleoside structure.

[1]  Y. Endo,et al.  Anti-tumor mechanisms of 3'-ethynyluridine and 3'-ethynylcytidine as RNA synthesis inhibitors: development and characterization of 3'-ethynyluridine-resistant cells. , 1997, Cancer letters.

[2]  M. Fukushima,et al.  Nucleosides and Nucleotides. 158. 1-(3-C-Ethynyl-β-d-ribo-pentofuranosyl)- cytosine, 1-(3-C-Ethynyl-β-d-ribo-pentofuranosyl)uracil, and Their Nucleobase Analogues as New Potential Multifunctional Antitumor Nucleosides with a Broad Spectrum of Activity1 , 1996 .

[3]  W. Pieken,et al.  2'-DEOXY-2'-ALKOXYLAMINOURIDINES : NOVEL 2'-SUBSTITUTED URIDINES PREPARED BY INTRAMOLECULAR NUCLEOPHILIC RING OPENING OF 2,2'-O-ANHYDROURIDINES , 1996 .

[4]  M. Fukushima,et al.  Antitumor effect of a novel multifunctional antitumor nucleoside, 3'-ethynylcytidine, on human cancers. , 1996, Oncology reports.

[5]  A. Matsuda,et al.  Nucleosides and nucleotides. 152. 1-(3-C-Ethynyl-β-D-ribo-pentofuranosyl)uracil as a broad spectrum antitumor nucleoside , 1996 .

[6]  A. Matsuda,et al.  Nucleosides and nucleotides. 141. Chemical stability of a new antitumor nucleoside, 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine in alkaline medium: formation of 2'-C-cyano-2'-deoxy-1-beta-D-ribo-pentofuranosylcytosine and its antitumor activity. , 1995, Journal of medicinal chemistry.

[7]  V. Heinemann,et al.  Gemcitabine: metabolism, mechanisms of action, and self-potentiation. , 1995, Seminars in oncology.

[8]  A. Matsuda,et al.  2′-C-Cyano-2′-deoxy-1-β-D-arabinofuranosylcytosine (CNDAC): A Mechanism-Based DNA-Strand-Breaking Antitumor Nucleoside1 , 1995 .

[9]  I. Komáromi,et al.  Anti-HIV Derivatives of 1-(2,3-Dideoxy-3-N-hydroxyamino-β-D-threo-pentofuranosyl)thymine , 1994 .

[10]  A. Bitonti,et al.  Regression of human breast tumor xenografts in response to (E)-2'-deoxy-2'-(fluoromethylene)cytidine, an inhibitor of ribonucleoside diphosphate reductase. , 1994, Cancer research.

[11]  N. Minakawa,et al.  Nucleosides and nucleotides. 122. 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosylcytosine and its derivatives. A new class of nucleoside with a broad antitumor spectrum. , 1993, Journal of medicinal chemistry.

[12]  K. Čapek,et al.  Synthesis and anti-HIV activity of 3′-deoxy-3′-(N-hydroxyamino) analogues of nucleosides , 1992 .

[13]  A. Matsuda,et al.  Antitumor activity of a novel nucleoside, 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosylcytosine (CNDAC) against murine and human tumors. , 1992, Cancer letters.

[14]  A. Matsuda,et al.  Nucleosides and Nucleotides. 106. Synthesis and Biological Activity of 1-(2-Deoxy-2-hydroxyimino- or Methoxyimino-β-D-erythro-pentofuranosyl)-thymine and -Cytosine§,1 , 1992 .

[15]  Y. Cheng,et al.  Synthesis and anticancer and antiviral activities of various 2'- and 3'-methylidene-substituted nucleoside analogues and crystal structure of 2'-deoxy-2'-methylidenecytidine hydrochloride. , 1991, Journal of medicinal chemistry.

[16]  J. Bollinger,et al.  2'-Deoxy-2'-methylenecytidine and 2'-deoxy-2',2'-difluorocytidine 5'-diphosphates: potent mechanism-based inhibitors of ribonucleotide reductase. , 1991, Journal of medicinal chemistry.

[17]  A. Matsuda,et al.  Antitumor activity of 2'-deoxy-2'-methylidenecytidine, a new 2'-deoxycytidine derivative. , 1991, Cancer research.

[18]  A. Matsuda,et al.  Nucleosides and nucleotides. 97. Synthesis of new broad spectrum antineoplastic nucleosides, 2'-deoxy-2'-methylidenecytidine (DMDC) and its derivatives. , 1991, Journal of medicinal chemistry.

[19]  G. Bernardinelli,et al.  Novel types of cyclonucleosides , 1990 .

[20]  J. G. Cory,et al.  Inhibitors of Ribonucleoside Diphosphate Reductase Activity , 1989 .

[21]  J. Tronchet,et al.  3′-Deoxy-3′-Hydroxyamino-β-D-Xylofuranosyluracil and Derivatives Thereof , 1988 .

[22]  James B. Mitchell,et al.  Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing. , 1987, Cancer research.

[23]  E. Moore,et al.  The inhibition of ribonucleoside diphosphate reductase by hydroxyurea, guanazole and pyrazoloimidazole (IMPY). , 1985, Pharmacology & therapeutics.

[24]  G. Weber.  Biochemical strategy of cancer cells and the design of chemotherapy: G. H. A. Clowes Memorial Lecture. , 1983, Cancer research.

[25]  E. Hayon,et al.  Intermediated produced from the one-electron oxidation and reduction of hydroxylamines. Acid-base properties of the amino, hydroxyamino, and methoxyamino radicals , 1971 .