Engineering a DNA damage response without DNA damage

[1]  T. Misteli,et al.  Activation of the Cellular DNA Damage Response in the Absence of DNA Lesions , 2008, Science.

[2]  D. Toczyski,et al.  Colocalization of sensors is sufficient to activate the DNA damage checkpoint in the absence of damage. , 2008, Molecular cell.

[3]  R. Kanaar,et al.  From DNA end chemistry to cell-cycle response: the importance of structure, even when it's broken. , 2008, Molecular cell.

[4]  R. Rothstein,et al.  Differential regulation of the cellular response to DNA double-strand breaks in G1. , 2008, Molecular cell.

[5]  I. Guerini,et al.  Surveillance mechanisms monitoring chromosome breaks during mitosis and meiosis. , 2008, DNA repair.

[6]  Laurence Pelletier,et al.  Orchestration of the DNA-Damage Response by the RNF8 Ubiquitin Ligase , 2007, Science.

[7]  Michael B. Yaffe,et al.  RNF8 Transduces the DNA-Damage Signal via Histone Ubiquitylation and Checkpoint Protein Assembly , 2007, Cell.

[8]  Jiri Bartek,et al.  RNF8 Ubiquitylates Histones at DNA Double-Strand Breaks and Promotes Assembly of Repair Proteins , 2007, Cell.

[9]  P. Jeggo,et al.  The impact of a negligent G2/M checkpoint on genomic instability and cancer induction , 2007, Nature Reviews Cancer.

[10]  P. Burgers,et al.  Clamping the Mec1/ATR Checkpoint Kinase into Action , 2007, Cell cycle.

[11]  J. Bartek,et al.  DNA damage checkpoints: from initiation to recovery or adaptation. , 2007, Current opinion in cell biology.

[12]  P. Jeggo,et al.  Chromosome breakage after G2 checkpoint release , 2007, The Journal of cell biology.

[13]  James E Haber,et al.  Surviving the breakup: the DNA damage checkpoint. , 2006, Annual review of genetics.

[14]  S. Bekker-Jensen,et al.  Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1 , 2005, The Journal of cell biology.

[15]  Marco Foiani,et al.  DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1 , 2004, Nature.

[16]  Michael Lichten,et al.  Distribution and Dynamics of Chromatin Modification Induced by a Defined DNA Double-Strand Break , 2004, Current Biology.

[17]  J. Haber,et al.  Regulation of Saccharomyces Rad53 checkpoint kinase during adaptation from DNA damage-induced G2/M arrest. , 2001, Molecular cell.

[18]  E. Rogakou,et al.  Megabase Chromatin Domains Involved in DNA Double-Strand Breaks in Vivo , 1999, The Journal of cell biology.

[19]  Jiri Bartek,et al.  ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks , 2006, Nature Cell Biology.