ATP-Driven Synthetic Supramolecular Assemblies: From ATP as a Template to Fuel.

Adenosine triphosphate (ATP) is the molecular unit of energy that drives various processes in the cellular environment. In this minireview, we discuss the potential of physical and chemical properties of ATP for the development of bio-inspired, synthetic ATP-induced supramolecular systems with dynamic, stimuli-responsive and active assembly characteristics. Molecular design rules for ATP-induced assemblies with various architectures and their stimuli-responsive structural and functional response is categorized. Special attention is given to the immense potential of ATP-fuelled design in the nascent field of transient/non-equilibrium supramolecular polymerization for the synthesis of lifelike temporally programmable soft materials. Finally, the existing dearth and leading fate of ATP-driven systems for future challenges are proposed.

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