Comparison of different classification algorithms in clinical decision‐making

: This paper gives an integrated view of implementing automated diagnostic systems for clinical decision-making. Because of the importance of making the right decision, better classification procedures are necessary for clinical decisions. The major objective of the paper is to be a guide for readers who want to develop an automated decision support system for clinical practice. The purpose was to determine an optimum classification scheme with high diagnostic accuracy for this problem. Several different classification algorithms were tested and benchmarked for their performance. The performance of the classification algorithms is illustrated on two data sets: the Pima Indians diabetes and the Wisconsin breast cancer. The present research demonstrates that the support vector machines achieved diagnostic accuracies which were higher than those of other automated diagnostic systems.

[1]  Elif Derya Übeyli,et al.  Neural network analysis of internal carotid arterial Doppler signals: predictions of stenosis and occlusion , 2003, Expert Syst. Appl..

[2]  Janette B. Bradley,et al.  Neural networks: A comprehensive foundation: S. HAYKIN. New York: Macmillan College (IEEE Press Book) (1994). v + 696 pp. ISBN 0-02-352761-7 , 1995 .

[3]  R. Setiono Extracting Rules from Pruned Neural Networks for Breast Cancer Diagnosis , 1996 .

[4]  Bert A. Mobley,et al.  Predictions of coronary artery stenosis by artificial neural network , 2000, Artif. Intell. Medicine.

[5]  O. Mangasarian,et al.  Multisurface method of pattern separation for medical diagnosis applied to breast cytology. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[6]  Parag C. Pendharkar,et al.  Association, statistical, mathematical and neural approaches for mining breast cancer patterns , 1999 .

[7]  Chong-Ho Choi,et al.  Input feature selection for classification problems , 2002, IEEE Trans. Neural Networks.

[8]  Mann A. Shoffner,et al.  Application of backpropagation neural networks to diagnosis of breast and ovarian cancer. , 1994, Cancer letters.

[9]  Mohammad Bagher Menhaj,et al.  Training feedforward networks with the Marquardt algorithm , 1994, IEEE Trans. Neural Networks.

[10]  Drasko Furundzic,et al.  Neural networks approach to early breast cancer detection , 1998, J. Syst. Archit..

[11]  Robert A. Jacobs,et al.  Hierarchical Mixtures of Experts and the EM Algorithm , 1993, Neural Computation.

[12]  Ke Chen,et al.  Improved learning algorithms for mixture of experts in multiclass classification , 1999, Neural Networks.

[13]  Vivian West,et al.  Model selection for a medical diagnostic decision support system: a breast cancer detection case , 2000, Artif. Intell. Medicine.

[14]  Elif Derya Übeyli,et al.  ECG beat classifier designed by combined neural network model , 2005, Pattern Recognit..

[15]  Michael I. Jordan,et al.  Hierarchical Mixtures of Experts and the EM Algorithm , 1994, Neural Computation.

[16]  Murali S. Shanker,et al.  Using Neural Networks To Predict the Onset of Diabetes Mellitus , 1996, J. Chem. Inf. Comput. Sci..

[17]  P. Snow,et al.  Artificial neural networks: current status in cardiovascular medicine. , 1996, Journal of the American College of Cardiology.

[18]  G Reibnegger,et al.  Artificial Neural Networks in Laboratory Medicine and Medical Outcome Prediction , 1999, Clinical chemistry and laboratory medicine.

[19]  B. H. Blott,et al.  Review of neural network applications in medical imaging and signal processing , 1992, Medical and Biological Engineering and Computing.

[20]  Bidyut Baran Chaudhuri,et al.  Efficient training and improved performance of multilayer perceptron in pattern classification , 2000, Neurocomputing.

[21]  Jeffrey L. Elman,et al.  Finding Structure in Time , 1990, Cogn. Sci..

[22]  Rudy Setiono,et al.  Generating concise and accurate classification rules for breast cancer diagnosis , 2000, Artif. Intell. Medicine.

[23]  Elif Derya Übeyli,et al.  Feature extraction from Doppler ultrasound signals for automated diagnostic systems , 2005, Comput. Biol. Medicine.

[24]  Pineda,et al.  Generalization of back-propagation to recurrent neural networks. , 1987, Physical review letters.

[25]  D B Fogel,et al.  Evolving neural networks for detecting breast cancer. , 1995, Cancer letters.

[26]  G. Besser,et al.  Clinical diabetes : an illustrated text , 1988 .

[27]  Donald C. Wunsch,et al.  Recurrent neural network based prediction of epileptic seizures in intra- and extracranial EEG , 2000, Neurocomputing.

[28]  Roberto Battiti,et al.  First- and Second-Order Methods for Learning: Between Steepest Descent and Newton's Method , 1992, Neural Computation.

[29]  Chee Peng Lim,et al.  Application of autonomous neural network systems to medical pattern classification tasks , 1997, Artif. Intell. Medicine.

[30]  I A Basheer,et al.  Artificial neural networks: fundamentals, computing, design, and application. , 2000, Journal of microbiological methods.

[31]  Xia Hong,et al.  A Mixture of Experts Network Structure Construction Algorithm for Modelling and Control , 2001, Applied Intelligence.

[32]  C. Floyd,et al.  Prediction of breast cancer malignancy using an artificial neural network , 1994, Cancer.

[33]  Elif Derya Übeyli,et al.  Detection of ophthalmic artery stenosis by least-mean squares backpropagation neural network , 2003, Comput. Biol. Medicine.

[34]  Elif Derya Übeyli,et al.  A mixture of experts network structure for modelling Doppler ultrasound blood flow signals , 2005, Comput. Biol. Medicine.

[35]  Jiann-Shing Shieh,et al.  Intracranial pressure model in intensive care unit using a simple recurrent neural network through time , 2004, Neurocomputing.

[36]  Hussein A. Abbass,et al.  An evolutionary artificial neural networks approach for breast cancer diagnosis , 2002, Artif. Intell. Medicine.

[37]  David H. Wolpert,et al.  Stacked generalization , 1992, Neural Networks.

[38]  Donald F. Specht,et al.  Probabilistic neural networks , 1990, Neural Networks.

[39]  Pietro Burrascano,et al.  Learning vector quantization for the probabilistic neural network , 1991, IEEE Trans. Neural Networks.

[40]  Geoffrey E. Hinton,et al.  Adaptive Mixtures of Local Experts , 1991, Neural Computation.

[41]  Jin Park,et al.  A sequential neural network model for diabetes prediction , 2001, Artif. Intell. Medicine.

[42]  Kai Liu,et al.  A novel large-memory neural network as an aid in medical diagnosis applications , 2001, IEEE Transactions on Information Technology in Biomedicine.