Molecular Alterations Associated with the NMDA Preconditioning-Induced Neuroprotective Mechanism Against Glutamate Cytotoxicity

[1]  Yael Bromberg,et al.  Neuroprotection by NMDA Preconditioning Against Glutamate Cytotoxicity is Mediated Through Activation of ERK 1/2, Inactivation of JNK, and by Prevention of Glutamate-Induced CREB Inactivation , 2011, Journal of Molecular Neuroscience.

[2]  G. Hardingham.  Coupling of the NMDA receptor to neuroprotective and neurodestructive events. , 2009, Biochemical Society transactions.

[3]  P. Pelicci,et al.  The cardioprotective effects elicited by p66(Shc) ablation demonstrate the crucial role of mitochondrial ROS formation in ischemia/reperfusion injury. , 2009, Biochimica et biophysica acta.

[4]  S. Miyamoto,et al.  Akt mediated mitochondrial protection in the heart: metabolic and survival pathways to the rescue , 2009, Journal of bioenergetics and biomembranes.

[5]  S. Steinberg,et al.  p66Shc Links &agr;1-Adrenergic Receptors to a Reactive Oxygen Species–Dependent AKT-FOXO3A Phosphorylation Pathway in Cardiomyocytes , 2009, Circulation research.

[6]  F. Miguel,et al.  Effect of acute vs chronic H2O2-induced oxidative stress on antioxidant enzyme activities , 2009, Free radical research.

[7]  A. Faisal,et al.  p66shc Inhibits Pro-survival Epidermal Growth Factor Receptor/ERK Signaling during Severe Oxidative Stress in Mouse Renal Proximal Tubule Cells* , 2008, Journal of Biological Chemistry.

[8]  S. Todo,et al.  Preventing hypoxia/reoxygenation damage to hepatocytes by p66(shc) ablation: up-regulation of anti-oxidant and anti-apoptotic proteins. , 2008, Journal of hepatology.

[9]  H. Otani.  Ischemic preconditioning: from molecular mechanisms to therapeutic opportunities. , 2008, Antioxidants & redox signaling.

[10]  V. Shani,et al.  Involvement of Src Tyrosine Kinases (SFKs) and of Focal Adhesion Kinase (FAK) in the Injurious Mechanism in Rat Primary Neuronal Cultures Exposed to Chemical Ischemia , 2008, Journal of Molecular Neuroscience.

[11]  G. Hardingham,et al.  The Dichotomy of NMDA Receptor Signaling , 2007, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.

[12]  F. Nicoletti,et al.  Metabotropic glutamate receptors in stem/progenitor cells , 2007, Neuropharmacology.

[13]  M. Mattson,et al.  Calcium and neurodegeneration , 2007, Aging cell.

[14]  R. Philp,et al.  PKC δ phosphorylates p52ShcA at Ser29 to regulate ERK activation in response to H2O2 , 2007 .

[15]  R. Philp,et al.  PKC delta phosphorylates p52ShcA at Ser29 to regulate ERK activation in response to H2O2. , 2007, Cellular signalling.

[16]  J. Cha,et al.  Ischemic preconditioning-induced activation of ERK1/2 in the rat hippocampus , 2006, Neuroscience Letters.

[17]  C. Franceschi,et al.  p66(Shc) gene has a pro-apoptotic role in human cell lines and it is activated by a p53-independent pathway. , 2006, Biochemical and biophysical research communications.

[18]  M. Hetman,et al.  Survival signaling pathways activated by NMDA receptors. , 2006, Current topics in medicinal chemistry.

[19]  H. Vaudry,et al.  N-Methyl-DD-aspartate Blocks Activation of JNK and Mitochondrial Apoptotic Pathway Induced by Potassium Deprivation in Cerebellar Granule Cells* , 2006, Journal of Biological Chemistry.

[20]  C. Y. Brazel,et al.  Glutamate enhances survival and proliferation of neural progenitors derived from the subventricular zone , 2005, Neuroscience.

[21]  A. Novelli,et al.  N‐methyl‐D‐aspartate and TrkB receptors protect neurons against glutamate excitotoxicity through an extracellular signal‐regulated kinase pathway , 2005, Journal of neuroscience research.

[22]  H. Canatan,et al.  Signal transduction mechanisms involved in cardiac preconditioning: Role of Ras-GTPase, Ca2 +/calmodulin-dependent protein kinase II and epidermal growth factor receptor , 2005, Molecular and Cellular Biochemistry.

[23]  C. Baldari,et al.  p66SHC: The apoptotic side of Shc proteins , 2005, Apoptosis.

[24]  P. Dodd,et al.  Glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer’s disease , 2004, Neurochemistry International.

[25]  Hajime Otani,et al.  Reactive oxygen species as mediators of signal transduction in ischemic preconditioning. , 2004, Antioxidants & redox signaling.

[26]  K. Shimamoto,et al.  The role of ADAM protease in the tyrosine kinase-mediated trigger mechanism of ischemic preconditioning. , 2004, Cardiovascular research.

[27]  P. Pagel,et al.  Protein Kinase C Translocation and Src Protein Tyrosine Kinase Activation Mediate Isoflurane-induced Preconditioning In Vivo: Potential Downstream Targets of Mitochondrial Adenosine Triphosphate–sensitive Potassium Channels and Reactive Oxygen Species , 2004, Anesthesiology.

[28]  Qin M. Chen,et al.  p66(Shc): at the crossroad of oxidative stress and the genetics of aging. , 2003, Trends in molecular medicine.

[29]  T. Obrenovitch,et al.  Spreading depression‐induced preconditioning in the mouse cortex: differential changes in the protein expression of ionotropic nicotinic acetylcholine and glutamate receptors , 2002, Journal of neurochemistry.

[30]  T. Kirino.  Ischemic Tolerance , 2002, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[31]  R. Bolli,et al.  Role of Src protein tyrosine kinases in late preconditioning against myocardial infarction. , 2002, American journal of physiology. Heart and circulatory physiology.

[32]  A. Maroney,et al.  c-Jun N-terminal Kinase Specifically Phosphorylates p66ShcA at Serine 36 in Response to Ultraviolet Irradiation* , 2001, The Journal of Biological Chemistry.

[33]  A. Ullrich,et al.  The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification. , 2001, Endocrine-related cancer.

[34]  C. Steinhäuser,et al.  Ionotropic glutamate receptors in astrocytes. , 2001, Progress in brain research.

[35]  B. Ahlemeyer,et al.  Preconditioning-induced neuroprotection is mediated by reactive oxygen species , 2000, Brain Research.

[36]  Pier Paolo Pandolfi,et al.  The p66shc adaptor protein controls oxidative stress response and life span in mammals , 1999, Nature.

[37]  J. Romashkova,et al.  NF-κB is a target of AKT in anti-apoptotic PDGF signalling , 1999, Nature.

[38]  D. Choi,et al.  Ischemic Tolerance in Murine Cortical Cell Culture: Critical Role for NMDA Receptors , 1999, The Journal of Neuroscience.

[39]  J. Romashkova,et al.  NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling. , 1999, Nature.

[40]  B. Margolis,et al.  The 66-kDa Shc Isoform Is a Negative Regulator of the Epidermal Growth Factor-stimulated Mitogen-activated Protein Kinase Pathway* , 1997, The Journal of Biological Chemistry.

[41]  G. Superti-Furga,et al.  Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor–MAP kinase–fos signalling pathway , 1997, The EMBO journal.

[42]  T. Salt,et al.  Functions of ionotropic and metabotropic glutamate receptors in sensory transmission in the mammalian thalamus , 1996, Progress in Neurobiology.

[43]  I. Fridovich,et al.  Superoxide radical and superoxide dismutases. , 1995, Annual review of biochemistry.

[44]  S. Paul,et al.  N-methyl-D-aspartate receptor-mediated neuroprotection in cerebellar granule cells requires new RNA and protein synthesis. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[45]  Yael Bromberg,et al.  Developmental Changes in the Activity of Enzymes of Purine Metabolism in Rat Neuronal Cells in Culture and in Whole Brain , 1990, Journal of neurochemistry.

[46]  H. Kontos,et al.  Oxygen radicals in CNS damage. , 1989, Chemico-biological interactions.

[47]  B. Halliwell,et al.  Oxygen toxicity, oxygen radicals, transition metals and disease. , 1984, The Biochemical journal.

[48]  M. M. Bradford.  A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. , 1976, Analytical biochemistry.