Bronchopleural Fistula after Lobectomy for Lung Cancer

Bronchopleural fistula after lung resection is a fatal complication. The aim of this study was to determine the risk factors for bronchopleural fistula after lobectomy for lung cancer. Clinical records of 767 patients who underwent lobectomy or bilobectomy for lung cancer in our institution were reviewed. Twelve patients (1.6%) suffered a bronchopleural fistula, of whom 5 died because of this complication (mortality rate, 41.7%). Multivariate analysis revealed squamous cell carcinoma, preoperative chemotherapy, lower lobectomy, and middle and lower lobectomy were risk factors for bronchopleural fistula. In such cases, particular care must be exercised to maintain blood flow through the bronchial stump during surgery, and reinforcement, such as stump coverage, must be employed.

[1]  M. Sonobe,et al.  Analysis of risk factors in bronchopleural fistula after pulmonary resection for primary lung cancer. , 2000, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[2]  A. Flahault,et al.  Pulmonary complications following lung resection: a comprehensive analysis of incidence and possible risk factors. , 2000, Chest.

[3]  H. Asamura,et al.  Management of the bronchial stump in pulmonary resections: a review of 533 consecutive recent bronchial closures. , 2000, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[4]  W. Klepetko,et al.  Impact of different coverage techniques on incidence of postpneumonectomy stump fistula. , 1999, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[5]  W G Henderson,et al.  Prognostic models of thirty-day mortality and morbidity after major pulmonary resection. , 1999, The Journal of thoracic and cardiovascular surgery.

[6]  G. Tsang,et al.  The threshold for air leak: stapled versus sutured human bronchi, and experimental study. , 1999, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[7]  J. V. D. van den Bosch,et al.  Completion pneumonectomy: analysis of operative mortality and survival. , 1998, The Annals of thoracic surgery.

[8]  J. Wain,et al.  Postpneumonectomy bronchopleural fistula after sutured bronchial closure: incidence, risk factors, and management. , 1996, The Journal of thoracic and cardiovascular surgery.

[9]  Green Mr,et al.  Multimodality therapy for non-small-cell lung cancer. , 1994 .

[10]  M. Green,et al.  Multimodality therapy for non-small-cell lung cancer. , 1994, Oncology.

[11]  R. Tsuchiya,et al.  Bronchopleural fistulas associated with lung cancer operations. Univariate and multivariate analysis of risk factors, management, and outcome. , 1992, The Journal of thoracic and cardiovascular surgery.

[12]  C. Kittle,et al.  Bronchopleural fistula after stapled closure of bronchus. , 1991, The Annals of thoracic surgery.

[13]  T. Shields,et al.  General Thoracic Surgery , 1972 .

[14]  J. Mathey,et al.  [Complications of pulmonary resections for tuberculosis]. , 1950, Revue de la tuberculose.