Aspirin inhibits the proliferation of hepatoma cells through controlling GLUT1-mediated glucose metabolism

[1]  Lei Han,et al.  Effects of Glut1 gene silencing on proliferation, differentiation, and apoptosis of colorectal cancer cells by targeting the TGF‐β/PI3K‐AKT‐mTOR signaling pathway , 2018, Journal of cellular biochemistry.

[2]  Yuen Gao,et al.  Hepatitis B virus X protein–elevated MSL2 modulates hepatitis B virus covalently closed circular DNA by inducing degradation of APOBEC3B to enhance hepatocarcinogenesis , 2017, Hepatology.

[3]  Young Youn Cho,et al.  Antiplatelet therapy and the risk of hepatocellular carcinoma in chronic hepatitis B patients on antiviral treatment , 2017, Hepatology.

[4]  I. Ong,et al.  PKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis , 2017, Nature Cell Biology.

[5]  H. Risch Aspirin and Pancreatic Cancer—Response , 2017, Cancer Epidemiology, Biomarkers & Prevention.

[6]  L. Ye,et al.  Aspirin suppresses the abnormal lipid metabolism in liver cancer cells via disrupting an NFκB-ACSL1 signaling. , 2017, Biochemical and biophysical research communications.

[7]  Xiaoling Liu,et al.  Aspirin regulation of c-myc and cyclinD1 proteins to overcome tamoxifen resistance in estrogen receptor-positive breast cancer cells , 2017, Oncotarget.

[8]  D. Wodarz,et al.  Aspirin-Induced Chemoprevention and Response Kinetics Are Enhanced by PIK3CA Mutations in Colorectal Cancer Cells , 2017, Cancer Prevention Research.

[9]  Michael P. Lisanti,et al.  Cancer metabolism: a therapeutic perspective , 2017, Nature Reviews Clinical Oncology.

[10]  Xiaoying Lin,et al.  Effects of G6PD activity inhibition on the viability, ROS generation and mechanical properties of cervical cancer cells. , 2016, Biochimica et biophysica acta.

[11]  Bing-Zhong Xu,et al.  Aspirin inhibits the proliferation and migration of gastric cancer cells in p53-knockout mice , 2016, Oncology letters.

[12]  M. Manns,et al.  Dual Role of the Adaptive Immune System in Liver Injury and Hepatocellular Carcinoma Development. , 2016, Cancer cell.

[13]  I. Ng,et al.  Down‐regulation of TIMP2 by HIF‐1α/miR‐210/HIF‐3α regulatory feedback circuit enhances cancer metastasis in hepatocellular carcinoma , 2016, Hepatology.

[14]  T. Das,et al.  Aspirin Suppresses the Acquisition of Chemoresistance in Breast Cancer by Disrupting an NFκB-IL6 Signaling Axis Responsible for the Generation of Cancer Stem Cells. , 2016, Cancer research.

[15]  Yin Cao,et al.  Aspirin and colorectal cancer: the promise of precision chemoprevention , 2016, Nature Reviews Cancer.

[16]  Ji Luo,et al.  NAFLD causes selective CD4+ T lymphocyte loss and promotes hepatocarcinogenesis , 2016, Nature.

[17]  K. Kashfi,et al.  NOSH-Aspirin Inhibits Colon Cancer Cell Growth: Effects Of Positional Isomerism. , 2015, Redox biology.

[18]  X. You,et al.  The oncoprotein HBXIP promotes glucose metabolism reprogramming via downregulating SCO2 and PDHA1 in breast cancer , 2015, Oncotarget.

[19]  K. Hu,et al.  Aspirin Suppresses the Growth and Metastasis of Osteosarcoma through the NF-κB Pathway , 2015, Clinical Cancer Research.

[20]  Juan Liu,et al.  RRAD inhibits the Warburg effect through negative regulation of the NF-κB signaling , 2015, Oncotarget.

[21]  R. Deberardinis,et al.  Metabolic pathways promoting cancer cell survival and growth , 2015, Nature Cell Biology.

[22]  Hushan Yang,et al.  CD147 promotes reprogramming of glucose metabolism and cell proliferation in HCC cells by inhibiting the p53-dependent signaling pathway. , 2014, Journal of hepatology.

[23]  Chunping Jiang,et al.  The Role of Hypoxia Inducible Factor-1 in Hepatocellular Carcinoma , 2014, BioMed research international.

[24]  D. Son,et al.  Aspirin Blocks EGF-stimulated Cell Viability in a COX-1 Dependent Manner in Ovarian Cancer Cells , 2013, Journal of Cancer.

[25]  X. You,et al.  The oncoprotein HBXIP up-regulates Skp2 via activating transcription factor E2F1 to promote proliferation of breast cancer cells. , 2013, Cancer letters.

[26]  B. Thorens,et al.  The SLC2 (GLUT) family of membrane transporters. , 2013, Molecular aspects of medicine.

[27]  Liu Wei,et al.  LKB1 inactivation dictates therapeutic response of non-small cell lung cancer to the metabolism drug phenformin. , 2013, Cancer cell.

[28]  Youliang Wang,et al.  Hepatitis B virus X protein modulates oncogene yes‐associated protein by CREB to promote growth of hepatoma cells , 2012, Hepatology.

[29]  K. Pacak,et al.  NF‐κB inhibition significantly upregulates the norepinephrine transporter system, causes apoptosis in pheochromocytoma cell lines and prevents metastasis in an animal model , 2012, International journal of cancer.

[30]  S. Safe,et al.  Aspirin Inhibits Colon Cancer Cell and Tumor Growth and Downregulates Specificity Protein (Sp) Transcription Factors , 2012, PloS one.

[31]  P. Rothwell,et al.  Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials , 2012, The Lancet.

[32]  A. Barsegian,et al.  Hydrogen sulfide-releasing aspirin suppresses NF-κB signaling in estrogen receptor negative breast cancer cells in vitro and in vivo. , 2012, Biochemical pharmacology.

[33]  B. Rigas,et al.  Chemotherapeutic properties of phospho-nonsteroidal anti-inflammatory drugs, a new class of anticancer compounds. , 2011, Cancer research.

[34]  Xiaodong Sun,et al.  Effect of Aspirin on the Expression of Hepatocyte NF-κB and Serum TNF-α in Streptozotocin-Induced Type 2 Diabetic Rats , 2011, Journal of Korean medical science.

[35]  C. Van Waes,et al.  ΔNp63 versatilely regulates a Broad NF-κB gene program and promotes squamous epithelial proliferation, migration, and inflammation. , 2011, Cancer research.

[36]  D. Hanahan,et al.  Hallmarks of Cancer: The Next Generation , 2011, Cell.

[37]  G. Semenza Regulation of metabolism by hypoxia-inducible factor 1. , 2011, Cold Spring Harbor symposia on quantitative biology.

[38]  E. Fontaine,et al.  Aspirin and non-small cell lung cancer resections: effect on long-term survival. , 2010, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[39]  G. Feldmann,et al.  The angiotensin-I-converting enzyme inhibitor enalapril and aspirin delay progression of pancreatic intraepithelial neoplasia and cancer formation in a genetically engineered mouse model of pancreatic cancer , 2009, Gut.

[40]  R. O. Poyton,et al.  Mitochondrial generation of free radicals and hypoxic signaling , 2009, Trends in Endocrinology & Metabolism.

[41]  Katerina Akassoglou,et al.  NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α , 2008, Nature.

[42]  J. Fong,et al.  Endothelin-1 induces glut1 transcription through enhanced interaction between Sp1 and NF-kappaB transcription factors. , 2008, Cellular signalling.

[43]  A. Mobasheri,et al.  Hypoxic Regulation of Glucose Transport, Anaerobic Metabolism and Angiogenesis in Cancer: Novel Pathways and Targets for Anticancer Therapeutics , 2007, Chemotherapy.

[44]  H. El‐Serag,et al.  Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. , 2007, Gastroenterology.

[45]  Max Costa,et al.  Hypoxia-Inducible Factor-1 (HIF-1) , 2006, Molecular Pharmacology.

[46]  G. Semenza Targeting HIF-1 for cancer therapy , 2003, Nature Reviews Cancer.

[47]  K. Petersen,et al.  Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes. , 2002, The Journal of clinical investigation.

[48]  K. Migita,et al.  Aspirin and NS‐398 inhibit hepatocyte growth factor–induced invasiveness of human hepatoma cells , 2002, Hepatology.

[49]  G. Owen,et al.  Glucose transporters: expression, regulation and cancer. , 2002, Biological research.

[50]  F. Ismail-Beigi,et al.  Regulation of glut1 mRNA by Hypoxia-inducible Factor-1 , 2001, The Journal of Biological Chemistry.

[51]  R. Gaynor,et al.  The anti-inflammatory agents aspirin and salicylate inhibit the activity of IκB kinase-β , 1998, Nature.

[52]  R. Gaynor,et al.  The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta. , 1998, Nature.

[53]  S. Ghosh,et al.  Inhibition of NF-kappa B by sodium salicylate and aspirin. , 1994, Science.

[54]  D. Woodfield Hepatocellular carcinoma. , 1986, The New Zealand medical journal.