Heparinase I acts on a synthetic heparin pentasaccharide corresponding to the antithrombin III binding site.

[1]  M. Sobel,et al.  Development of heparin antagonists with focused biological activity. , 1999, Current pharmaceutical design.

[2]  R. Porsche,et al.  Allergy to protamine sulfate. , 1999, Heart & lung : the journal of critical care.

[3]  J. Carr,et al.  The heparin-protamine interaction. A review. , 1999, The Journal of cardiovascular surgery.

[4]  B. Lucchesi,et al.  Ex vivo reversal of heparin-mediated cardioprotection by heparinase after ischemia and reperfusion. , 1999, The Journal of pharmacology and experimental therapeutics.

[5]  D. Hoppensteadt,et al.  Low-molecular-weight heparins: pharmacologic profile and product differentiation. , 1998, The American journal of cardiology.

[6]  D. H. Kim,et al.  Determination of the structure of oligosaccharides prepared from acharan sulfate. , 1998, Glycobiology.

[7]  K. Biemann,et al.  Direct evidence for a predominantly exolytic processive mechanism for depolymerization of heparin-like glycosaminoglycans by heparinase I. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[8]  S. Yamada,et al.  Structure of Oligosaccharides Isolated from Heparan Sulfate/Heparin and Substrate Specificities of the Degrading Enzymes of Bacterial Origin , 1998 .

[9]  M. Samama,et al.  Biochemical and pharmacologic rationale for the development of a synthetic heparin pentasaccharide. , 1997, Thrombosis research.

[10]  M. Kikura,et al.  Heparinase I (Neutralase) Reversal of Systemic Anticoagulation , 1996, Anesthesiology.

[11]  J. Levy,et al.  Heparin Neutralization by Recombinant Platelet Factor 4 and Protamine , 1995, Anesthesia and analgesia.

[12]  U. R. Desai,et al.  Substrate specificity of the heparin lyases from Flavobacterium heparinum. , 1993, Archives of biochemistry and biophysics.

[13]  U. R. Desai,et al.  Specificity studies on the heparin lyases from Flavobacterium heparinum. , 1993, Biochemistry.

[14]  J. Weiler,et al.  Gradient polyacrylamide gel electrophoresis for determination of molecular weights of heparin preparations and low-molecular-weight heparin derivatives. , 1992, Journal of pharmaceutical sciences.

[15]  R. Linhardt,et al.  Examination of the substrate specificity of heparin and heparan sulfate lyases. , 1990, Biochemistry.

[16]  R. Linhardt,et al.  Study of structurally defined oligosaccharide substrates of heparin and heparan monosulfate lyases. , 1989, Carbohydrate research.

[17]  M. Samama,et al.  Amidolytic Antifactor Xa Assays in the Laboratory Evaluation of Heparin and Low Molecular Weight Fractions , 1985, Seminars in thrombosis and hemostasis.

[18]  R. Langer,et al.  An enzymatic system for removing heparin in extracorporeal therapy. , 1982, Science.

[19]  T BITTER,et al.  A modified uronic acid carbazole reaction. , 1962, Analytical biochemistry.

[20]  V. Wiwanitkit.  Thrombosis Research , 2023 .

[21]  J. Fareed,et al.  In vitro studies on the biochemistry and pharmacology of low molecular weight heparins. , 1999, Seminars in thrombosis and hemostasis.

[22]  G. Agnelli,et al.  Management of Oral Anticoagulant Therapy in Italy , 1999, Seminars in thrombosis and hemostasis.