Radiation sensitivity of Bacillus megaterium spores in the presence of Co(III)complexes.

Investigation of radiation sensitization by cobalt hexammine chloride of B. megaterium spores either in aqueous suspension or equilibrated at 22 torr water vapor pressure reveals a unique duplication of sensitizing action in both the presence and absence of oxygen. Ethanol reverses this cobalt-complex sensitizing in anoxic, but not oxic, spore suspensions, whereas t-butanol has no protective effect. A series of Co(III) complexes is tested for anoxic sensitization to compare with hexammine complex. The sensitizing ability of these compounds is much reduced or absent when bidentate or multidentate organic ligands replace the ammine coordinates to cobalt. (auth)

[1]  E. L. Powers,et al.  Modification of radiation sensitivity of bacterial spores by silver salts. , 1974, Radiation research.

[2]  M. Hoffman,et al.  Rate of reduction of cobalt(III) complexes by carbon dioxide(CO2.-) radicals in aqueous solution , 1973 .

[3]  E. L. Powers,et al.  Further Evidence for a Role of H2O2 in Radiation Sensitization of Bacterial Spores , 1973 .

[4]  N. F. Curtis Macrocyclic coordination compounds formed by condensation of metal-amine complexes with aliphatic carbonyl compounds , 1968 .

[5]  M. Anbar,et al.  A compilation of specific bimolecular rate constants for the reactions of hydrated electrons, hydrogen atoms and hydroxyl radicals with inorganic and organic compounds in aqueous solution , 1967 .

[6]  E. L. Powers,et al.  MODIFICATION OF SENSITIVITY TO X-IRRADIATION BY WATER IN BACILLUS MEGATERIUM. , 1963, Radiation research.

[7]  E. L. Powers,et al.  The membrane filter technique in radiation studies of spores of Bacillus megaterium. , 1957, Applied microbiology.

[8]  J. Lilie,et al.  Kinetics of ammonia detachment from reduced cobalt(III) complexes based on conductometric pulse radiolysis , 1974 .

[9]  A. B. Jones,et al.  Radiosensitization of bacterial spores by potassium permanganate. , 1973, International journal of radiation biology and related studies in physics, chemistry, and medicine.

[10]  E. Hayon,et al.  A model of radiation sensitization by quinones. , 1972, International journal of radiation biology and related studies in physics, chemistry, and medicine.

[11]  E. L. Powers,et al.  H 2 O 2 and OH radicals in radiation inactivation of bacterial spores. , 1972, International journal of radiation biology and related studies in physics, chemistry, and medicine.

[12]  G. P. Jacobs,et al.  The Radiosensitizing Actions of Ketonic Agents and Oxygen in Bacterial Spores Suspended in Aqueous and Non-Aqueous Milieux , 1972 .

[13]  E. L. Powers,et al.  Nitrous oxide as a sensitizer of bacterial spores to x-rays. , 1970, International journal of radiation biology and related studies in physics, chemistry, and medicine.

[14]  G. Adams,et al.  Electron-affinic sensitization. I. A structural basis for chemical radiosensitizers in bacteria. , 1969, International Journal of Radiation Biology and Related Studies in Physics Chemistry and Medicine.

[15]  E. L. Powers,et al.  2,3-butanedione, an electron-stabilizing compound, as a modifier of sensitivy of Bacillus megaterium spores to X-rays. , 1968, International journal of radiation biology and related studies in physics, chemistry, and medicine.