What is evidence-based medicine?

[1]  P Kinnersley,et al.  Shared decision making and the concept of equipoise: the competences of involving patients in healthcare choices. , 2000, The British journal of general practice : the journal of the Royal College of General Practitioners.

[2]  G. Guyatt,et al.  Users' Guides to the Medical Literature: XXV. Evidence-based medicine: principles for applying the Users' Guides to patient care. Evidence-Based Medicine Working Group. , 2000, JAMA.

[3]  L. Hegedüs,et al.  Management of the solitary thyroid nodule: results of a North American survey. , 2000, The Journal of clinical endocrinology and metabolism.

[4]  J. Concato,et al.  Randomized, controlled trials, observational studies, and the hierarchy of research designs. , 2000, The New England journal of medicine.

[5]  A. Hartz,et al.  A comparison of observational studies and randomized, controlled trials , 2000, American journal of ophthalmology.

[6]  M. Mayo-Smith,et al.  Are guidelines following guidelines? The methodological quality of clinical practice guidelines in the peer-reviewed medical literature. , 1999, JAMA.

[7]  A. Laupacis,et al.  Theophylline for irreversible chronic airflow limitation: a randomized study comparing n of 1 trials to standard practice. , 1999, Chest.

[8]  S Hulley,et al.  Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group. , 1998, JAMA.

[9]  A. Feinstein,et al.  Problems in the "evidence" of "evidence-based medicine". , 1997, The American journal of medicine.

[10]  Guyatt,et al.  Evidence-based Health Care. , 1997, Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology.

[11]  H. Hricak,et al.  Evidence-based medicine. , 1997, Singapore medical journal.

[12]  A Donner,et al.  Randomised study of n of 1 trials versus standard practice , 1996, BMJ.

[13]  D. Sackett,et al.  Evidence based medicine: what it is and what it isn't , 1996, BMJ.

[14]  D. Naylor.  Cost-effectiveness analysis: are the outputs worth the inputs? , 1996, ACP journal club.

[15]  R J Cook,et al.  Users' guides to the medical literature. IX. A method for grading health care recommendations. Evidence-Based Medicine Working Group. , 1995, JAMA.

[16]  R S Hayward,et al.  Users' guides to the medical literature. VIII. How to use clinical practice guidelines. A. Are the recommendations valid? The Evidence-Based Medicine Working Group. , 1995, JAMA.

[17]  R B Haynes,et al.  Bridges between health care research evidence and clinical practice. , 1995, Journal of the American Medical Informatics Association : JAMIA.

[18]  C. Naylor,et al.  Variation in breast cancer surgery in Ontario. , 1994, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

[19]  D. Sackett.  The Cochrane Collaboration. , 1994, ACP journal club.

[20]  A. Detsky,et al.  Evidence-based medicine. A new approach to teaching the practice of medicine. , 1992, JAMA.

[21]  D. DeMets,et al.  Effect of oral milrinone on mortality in severe chronic heart failure. The PROMISE Study Research Group. , 1991, The New England journal of medicine.

[22]  D. Sackett,et al.  Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. , 1991, The New England journal of medicine.

[23]  H L Greene,et al.  Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial. , 1991, The New England journal of medicine.

[24]  G. Colditz,et al.  Estrogen replacement therapy and coronary heart disease: A quantitative assessment of the epidemiologic evidence☆☆☆ , 1991 .

[25]  W M O'Fallon,et al.  Effect of fluoride treatment on the fracture rate in postmenopausal women with osteoporosis. , 1990, The New England journal of medicine.

[26]  G H Guyatt,et al.  The n-of-1 randomized controlled trial: clinical usefulness. Our three-year experience. , 1990, Annals of internal medicine.

[27]  J. Lomas,et al.  Regionalization of Coronary Artery Bypass Surgery: Effects on Access , 1989, Medical care.

[28]  C. Mulrow,et al.  Relative efficacy of vasodilator therapy in chronic congestive heart failure. Implications of randomized trials. , 1988, JAMA.

[29]  S. Bloom,et al.  Improvement in headache associated with prolactinoma during treatment with a somatostatin analogue: an "N of 1" study. , 1986, The New England journal of medicine.

[30]  G. Guyatt,et al.  Determining optimal therapy--randomized trials in individual patients. , 1986, The New England journal of medicine.

[31]  J. Wergedal,et al.  Fluoride directly stimulates proliferation and alkaline phosphatase activity of bone-forming cells. , 1983, Science.

[32]  I. Chalmers.  Scientific inquiry and authoritarianism in perinatal care and education. , 1983, Birth.

[33]  D Light,et al.  Uncertainty and control in professional training. , 1979, Journal of health and social behavior.