Globotriaosyl ceramide (CD77/Gb3) in the glycolipid-enriched membrane domain participates in B-cell receptor-mediated apoptosis by regulating lyn kinase activity in human B cells.

[1]  M. Aman,et al.  A requirement for lipid rafts in B cell receptor induced Ca2+ flux , 2000, Current Biology.

[2]  Tetsuya Mori,et al.  Activation of Src Family Kinase Yes Induced by Shiga Toxin Binding to Globotriaosyl Ceramide (Gb3/CD77) in Low Density, Detergent-insoluble Microdomains* , 1999, The Journal of Biological Chemistry.

[3]  P. W. Janes,et al.  Aggregation of Lipid Rafts Accompanies Signaling via the T Cell Antigen Receptor , 1999, The Journal of cell biology.

[4]  M. Fujimoto,et al.  CD19 amplifies B lymphocyte signal transduction by regulating Src-family protein tyrosine kinase activation. , 1999, Journal of immunology.

[5]  C. Peschle,et al.  Phorbol Ester-induced Disruption of the CD4-Lck Complex Occurs within a Detergent-resistant Microdomain of the Plasma Membrane , 1999, The Journal of Biological Chemistry.

[6]  K. Iwabuchi,et al.  Separation of “Glycosphingolipid Signaling Domain” from Caveolin-containing Membrane Fraction in Mouse Melanoma B16 Cells and Its Role in Cell Adhesion Coupled with Signaling* , 1998, The Journal of Biological Chemistry.

[7]  C. Lingwood,et al.  CD77‐dependent retrograde transport of CD19 to the nuclear membrane: Functional relationship between CD77 and CD19 during germinal center B‐cell apoptosis , 1998, Journal of cellular physiology.

[8]  H. Uchida,et al.  Induction of apoptosis in normal human renal tubular epithelial cells by Escherichia coli Shiga toxins 1 and 2. , 1998, The Journal of infectious diseases.

[9]  H. Uchida,et al.  Verotoxins induce apoptosis in human renal tubular epithelium derived cells. , 1998, Kidney international.

[10]  S. Robbins,et al.  Rapid Redistribution of CD20 to a Low Density Detergent-insoluble Membrane Compartment* , 1998, The Journal of Biological Chemistry.

[11]  Tadashi Yamamoto,et al.  Association of Src Family Tyrosine Kinase Lyn with Ganglioside GD3 in Rat Brain , 1997, The Journal of Biological Chemistry.

[12]  T. Tursz,et al.  Intracellular signaling events in CD77-mediated apoptosis of Burkitt's lymphoma cells. , 1997, Blood.

[13]  M. Hung,et al.  Mitosis-specific Negative Regulation of Epidermal Growth Factor Receptor, Triggered by a Decrease in Ligand Binding and Dimerization, Can Be Overcome by Overexpression of Receptor* , 1997, The Journal of Biological Chemistry.

[14]  K. Handa,et al.  A close association of GM3 with c-Src and Rho in GM3-enriched microdomains at the B16 melanoma cell surface membrane: a preliminary note. , 1997, Biochemical and biophysical research communications.

[15]  E. Ikonen,et al.  Functional rafts in cell membranes , 1997, Nature.

[16]  D. Milford,et al.  Comparison of ribosome-inactivating proteins in the induction of apoptosis. , 1997, Toxicology letters.

[17]  B. Baird,et al.  Compartmentalized Activation of the High Affinity Immunoglobulin E Receptor within Membrane Domains* , 1997, The Journal of Biological Chemistry.

[18]  W. Rodgers,et al.  Exclusion of CD45 inhibits activity of p56lck associated with glycolipid-enriched membrane domains , 1996, The Journal of cell biology.

[19]  C. Peschle,et al.  Signal transduction and glycophosphatidylinositol-linked proteins (lyn, lck, CD4, CD45, G proteins, and CD55) selectively localize in Triton-insoluble plasma membrane domains of human leukemic cell lines and normal granulocytes. , 1996, Blood.

[20]  C. Goodnow Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[21]  J. Banchereau,et al.  Human germinal center B cells express the apoptosis-inducing genes Fas, c-myc, P53, and Bax but not the survival gene bcl-2 , 1996, The Journal of experimental medicine.

[22]  G. Schieven,et al.  Association of 75/80-kDa Phosphoproteins and the Tyrosine Kinases Lyn, Fyn, and Lck with the B Cell Molecule CD20 , 1995, The Journal of Biological Chemistry.

[23]  K. Simons,et al.  Digging into caveolae , 1995, Science.

[24]  E. Lindhout,et al.  Follicular dendritic cells inhibit apoptosis in human B lymphocytes by a rapid and irreversible blockade of preexisting endonuclease , 1995, The Journal of experimental medicine.

[25]  Kenneth G. C. Smith,et al.  Soluble antigen can cause enhanced apoptosis of germinal-centre B cells , 1995, Nature.

[26]  M. Hamaguchi,et al.  Ganglioside GM1 binds to the Trk protein and regulates receptor function. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[27]  E. London,et al.  Interactions between saturated acyl chains confer detergent resistance on lipids and glycosylphosphatidylinositol (GPI)-anchored proteins: GPI-anchored proteins in liposomes and cells show similar behavior. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[28]  T. Taki,et al.  Blotting of glycolipids and phospholipids from a high-performance thin-layer chromatogram to a polyvinylidene difluoride membrane. , 1994, Analytical biochemistry.

[29]  D. Brown,et al.  Triton X-100-resistant membrane complexes from cultured kidney epithelial cells contain the Src family protein tyrosine kinase p62yes. , 1994, The Journal of biological chemistry.

[30]  C. Lingwood,et al.  CD19 has a potential CD77 (globotriaosyl ceramide)-binding site with sequence similarity to verotoxin B-subunits: implications of molecular mimicry for B cell adhesion and enterohemorrhagic Escherichia coli pathogenesis , 1994, The Journal of experimental medicine.

[31]  V. Pascual,et al.  Analysis of somatic mutation in five B cell subsets of human tonsil , 1994, The Journal of experimental medicine.

[32]  T. Yamamoto,et al.  Syk activation by the Src-family tyrosine kinase in the B cell receptor signaling , 1994, The Journal of experimental medicine.

[33]  Z. Darżynkiewicz,et al.  A selective procedure for DNA extraction from apoptotic cells applicable for gel electrophoresis and flow cytometry. , 1994, Analytical biochemistry.

[34]  W. Swaim,et al.  Src family tyrosine kinase p53/56lyn, a serine kinase and Fc epsilon RI associate with alpha-galactosyl derivatives of ganglioside GD1b in rat basophilic leukemia RBL-2H3 cells. , 1994, The Journal of biological chemistry.

[35]  M. Resh,et al.  Myristylation and palmitylation of Src family members: The fats of the matter , 1994, Cell.

[36]  R. G. Anderson,et al.  Caveolae: where incoming and outgoing messengers meet. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[37]  B. Caillou,et al.  Apoptosis induced in Burkitt's lymphoma cells via Gb3/CD77, a glycolipid antigen. , 1993, Cancer research.

[38]  M. Lisanti,et al.  Signal transducing molecules and glycosyl-phosphatidylinositol-linked proteins form a caveolin-rich insoluble complex in MDCK cells , 1993, The Journal of cell biology.

[39]  Jing Wu,et al.  B-cell apoptosis induced by antigen receptor crosslinking is blocked by a T-cell signal through CD40 , 1993, Nature.

[40]  R. V. van Lier,et al.  The CR2/CD19 complex on human B cells contains the src-family kinase Lyn. , 1993, International immunology.

[41]  Jonathan A. Cooper,et al.  The when and how of Src regulation , 1993, Cell.

[42]  P. Dráber,et al.  Thy-1 glycoprotein and src-like protein-tyrosine kinase p53/p56lyn are associated in large detergent-resistant complexes in rat basophilic leukemia cells. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[43]  C. Berek,et al.  Maturation of the immune response in germinal centers , 1991, Cell.

[44]  Klaus Rajewsky,et al.  Intraclonal generation of antibody mutants in germinal centres , 1991, Nature.

[45]  T. Tursz,et al.  CD77: an antigen of germinal center B cells entering apoptosis , 1991, European journal of immunology.

[46]  I. Maclennan,et al.  Mechanism of antigen-driven selection in germinal centres , 1989, Nature.

[47]  N. Ling,et al.  A phenotypic study of cells from burkitt lymphoma and ebv‐b‐lymphoblastoid lines and their relationship to cells in normal lymphoid tissues , 1989, International journal of cancer.

[48]  E. Ishii,et al.  Immunocytological and immunochemical analysis on the common acute lymphoblastic leukemia antigen (CALLA): evidence that CALLA on ALL cells and granulocytes are structurally related. , 1988, Hybridoma.

[49]  M. Lipinski,et al.  Identification of a subset of normal B cells with a Burkitt's lymphoma (BL)-like phenotype. , 1987, Journal of immunology.

[50]  M. Noda,et al.  Purification and some properties of Shiga-like toxin from Escherichia coli O157:H7 that is immunologically identical to Shiga toxin. , 1987, Microbial pathogenesis.

[51]  M. Neuberger,et al.  Somatic hypermutation of immunoglobulin genes. , 1996, Annual review of immunology.

[52]  Lingwood Ca Verotoxins and their glycolipid receptors. , 1993 .