Laterality of hippocampal responses to infrequent and unpredictable omissions of visual stimuli

SummaryPrevious studies have demonstrated that externally measured magnetic field patterns are indicative of activity in the vicinity of the right hippocampal formation during infrequent and unpredictable intrusions or omissions of visual stimuli in an oddball evoked response paradigm. These fields occur coincident with late endogenous evoked potential components that are consistently recorded in similar situations. In the present study, magnetic fields temporally corresponding to the late P300 component of simultaneously recorded evoked potentials were accounted for by sources in the vicinity of the left and right hippocampus in addition to previously reported sources in the vicinity of the primary visual cortex. Projection of these sources onto MRIs suggested that both hippocampal structures are simultaneously active and that there is an amplitude and strength-related dominance of the right hippocampal sources to visual stimulation.

[1]  E. Harth,et al.  Electric Fields of the Brain: The Neurophysics of Eeg , 2005 .

[2]  R. Johnson,et al.  Developmental evidence for modality-dependent P300 generators: a normative study. , 1989, Psychophysiology.

[3]  W W Sutherling,et al.  Human hand and lip sensorimotor cortex as studied on electrocorticography. , 1992, Electroencephalography and clinical neurophysiology.

[4]  L. Kaufman,et al.  The hippocampal formation as a source of the slow endogenous potentials. , 1983, Electroencephalography and clinical neurophysiology.

[5]  E. Halgren,et al.  The intracranial topography of the P3 event-related potential elicited during auditory oddball. , 1990, Electroencephalography and clinical neurophysiology.

[6]  J Beatty,et al.  Magnetic localization of a dipolar current source implanted in a sphere and a human cranium. , 1986, Electroencephalography and clinical neurophysiology.

[7]  B. Milner,et al.  Right hippocampal impairment in the recall of spatial location: Encoding deficit or rapid forgetting? , 1989, Neuropsychologia.

[8]  L. Nadel.  The hippocampus and space revisited , 1991, Hippocampus.

[9]  S. Baumann,et al.  Localization of the P3 sources using magnetoencephalography and magnetic resonance imaging. , 1991, Electroencephalography and clinical neurophysiology.

[10]  J. Rohrbaugh,et al.  Endogenous potentials generated in the human hippocampal formation and amygdala by infrequent events. , 1980, Science.

[11]  S. Baumann,et al.  Spatially Distributed Cortical Excitation Patterns of Auditory Processing during Contralateral and Ipsilateral Stimulation , 1990, Journal of Cognitive Neuroscience.

[12]  S. Baumann,et al.  Neuromagnetic evidence of a dynamic excitation pattern generating the N100 auditory response. , 1990, Electroencephalography and clinical neurophysiology.

[13]  S. Yamaguchi,et al.  Anterior and posterior association cortex contributions to the somatosensory P300 , 1991, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[14]  L. Kaufman,et al.  Tonotopic organization of the human auditory cortex. , 1982, Science.

[15]  Samuel J. Williamson,et al.  Retinotopic map on the visual cortex for eccentrically placed patterns: First noninvasive measurement , 1983 .

[16]  R. Johnson,et al.  Auditory and visual P300s in temporal lobectomy patients: evidence for modality-dependent generators. , 1989, Psychophysiology.

[17]  A. Papanicolaou,et al.  Magnetoencephalography reveals two distinct sources associated with late positive evoked potentials during visual oddball task. , 1993, Cerebral cortex.

[18]  E Halgren,et al.  Endogenous potentials evoked in simple cognitive tasks: depth components and task correlates. , 1987, Electroencephalography and clinical neurophysiology.

[19]  L. Kaufman,et al.  Advances in neuromagnetic instrumentation and studies of spontaneous brain activity , 2005, Brain Topography.

[20]  S. Baumann,et al.  Localization of auditory response sources using magnetoencephalography and magnetic resonance imaging. , 1990, Archives of neurology.

[21]  J. Mäkelä,et al.  Modification of neuromagnetic responses of the human auditory cortex by masking sounds , 2004, Experimental Brain Research.

[22]  A. Papanicolaou,et al.  Visual evoked magnetic fields reveal activity in the superior temporal sulcus. , 1993, Electroencephalography and clinical neurophysiology.

[23]  S. Baumann,et al.  Late magnetic fields and positive evoked potentials following infrequent and unpredictable omissions of visual stimuli. , 1992, Electroencephalography and clinical neurophysiology.

[24]  C. C. Wood,et al.  Task-dependent field potentials in human hippocampal formation , 1989, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[25]  W W Sutherling,et al.  Spatiotemporal modeling of cerebral evoked magnetic fields to median nerve stimulation. , 1991, Electroencephalography and clinical neurophysiology.

[26]  Brenda Milner,et al.  The role of the right hippocampus in the recall of spatial location , 1981, Neuropsychologia.

[27]  P H Crandall,et al.  The magnetic and electric fields agree with intracranial localizations of somatosensory cortex , 1988, Neurology.

[28]  P. Nunez,et al.  Electric fields of the brain , 1981 .