Modeling inducible human tissue neoplasia identifies an extracellular matrix interaction network involved in cancer progression.
暂无分享,去创建一个
Howard Y. Chang | Howard Y Chang | Jason A. Reuter | M. Kretz | P. Khavari | F. A. Scholl | D. Cassarino | Susana Ortiz-Urda | Paul A Khavari | David Cassarino | S. Ortiz-Urda | Florence A Scholl | John Garcia | A. Pasmooij | Jason A Reuter | Markus Kretz | John Garcia | Anna M G Pasmooij | A. M. Pasmooij
[1] R. Weinberg,et al. Species- and cell type-specific requirements for cellular transformation. , 2004, Cancer cell.
[2] A. Fraser,et al. A single gene network accurately predicts phenotypic effects of gene perturbation in Caenorhabditis elegans , 2008, Nature Genetics.
[3] Jason A. Reuter,et al. Use of conditionally active ras fusion proteins to study epidermal growth, differentiation, and neoplasia. , 2006, Methods in enzymology.
[4] Paul A. Bates,et al. Global topological features of cancer proteins in the human interactome , 2006, Bioinform..
[5] J. Ott,et al. Genomic analysis defines a cancer-specific gene expression signature for human squamous cell carcinoma and distinguishes malignant hyperproliferation from benign hyperplasia. , 2006, The Journal of investigative dermatology.
[6] P. Marrack,et al. The function of antigen-presenting cells in mice with severe combined immunodeficiency. , 1985, Journal of immunology.
[7] E. Wayner,et al. Regulation of human B-cell precursor adhesion to bone marrow stromal cells by cytokines that exert opposing effects on the expression of vascular cell adhesion molecule-1 (VCAM-1) , 1993 .
[8] F. Watt,et al. New roles for integrins in squamous-cell carcinoma , 2006, Nature Reviews Cancer.
[9] P. Khavari,et al. Inducible activation of Ras and Raf in adult epidermis. , 2003, Cancer research.
[10] M. Weinstock,et al. Trends in nonmelanoma skin cancer mortality rates in the United States, 1969 through 2000. , 2005, The Journal of investigative dermatology.
[11] R. Tibshirani,et al. Significance analysis of microarrays applied to the ionizing radiation response , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[12] Patrick O. Brown,et al. Gene Expression Patterns in Pancreatic Tumors, Cells and Tissues , 2007, PloS one.
[13] Paul A. Khavari,et al. Modelling cancer in human skin tissue , 2006, Nature Reviews Cancer.
[14] Howard Y. Chang,et al. Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[15] R. Tibshirani,et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[16] W. Muller,et al. Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction. , 2004, Cancer cell.
[17] John S. Condeelis,et al. Identification and Testing of a Gene Expression Signature of Invasive Carcinoma Cells within Primary Mammary Tumors , 2004, Cancer Research.
[18] Conditional ablation of beta1 integrin in skin. Severe defects in epidermal proliferation, basement membrane formation, and hair follicle invagination. , 2000, The Journal of cell biology.
[19] Jennifer Y. Zhang,et al. Tumor necrosis factor receptor 1/c-Jun-NH2-kinase signaling promotes human neoplasia. , 2007, Cancer research.
[20] N. Fusenig,et al. Friends or foes — bipolar effects of the tumour stroma in cancer , 2004, Nature Reviews Cancer.
[21] A. Sparks,et al. The Genomic Landscapes of Human Breast and Colorectal Cancers , 2007, Science.
[22] D. Bae,et al. Expression profile of skin papillomas with high cancer risk displays a unique genetic signature that clusters with squamous cell carcinomas and predicts risk for malignant conversion , 2007, Oncogene.
[23] Brad T. Sherman,et al. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources , 2008, Nature Protocols.
[24] Z. Werb,et al. Coevolution of cancer and stromal cellular responses. , 2005, Cancer cell.
[25] A. Barabasi,et al. Lethality and centrality in protein networks , 2001, Nature.
[26] J. Mesirov,et al. An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis , 2005, Nature Genetics.
[27] K. Gunsalus,et al. Network modeling links breast cancer susceptibility and centrosome dysfunction. , 2007, Nature genetics.
[28] J. Vandenbroucke,et al. Incidence of skin cancer after renal transplantation in The Netherlands. , 1990, Transplantation.
[29] F. Watt,et al. Changes in the expression of αv integrins in oral squamous cell carcinomas , 1997 .
[30] A. Barabasi,et al. Drug—target network , 2007, Nature Biotechnology.
[31] B. Ganter,et al. Emerging applications of network and pathway analysis in drug discovery and development. , 2008, Current opinion in drug discovery & development.
[32] P. Khavari,et al. The Class II Phosphoinositide 3-Kinase C2β Is Not Essential for Epidermal Differentiation , 2005, Molecular and Cellular Biology.
[33] Eran Segal,et al. Module map of stem cell genes guides creation of epithelial cancer stem cells. , 2008, Cell stem cell.
[34] Jennifer Y. Zhang,et al. NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia. , 2003, Nature.
[35] Channing J Der,et al. Renewing the conspiracy theory debate: does Raf function alone to mediate Ras oncogenesis? , 2004, Trends in cell biology.
[36] Yudong D. He,et al. A Gene-Expression Signature as a Predictor of Survival in Breast Cancer , 2002 .
[37] M. Serrano,et al. A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors. , 2007, Genes & development.
[38] E. Fuchs,et al. Conditional ablation of beta1 integrin in skin. Severe defects in epidermal proliferation, basement membrane formation, and hair follicle invagination. , 2000, The Journal of cell biology.
[39] L. Chin,et al. Essential role for oncogenic Ras in tumour maintenance , 1999, Nature.
[40] Dennis C. Sgroi,et al. Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion , 2005, Cell.
[41] I. M. Neiman,et al. [Inflammation and cancer]. , 1974, Patologicheskaia fiziologiia i eksperimental'naia terapiia.
[42] K. Siziopikou,et al. The basal subtype of breast carcinomas may represent the group of breast tumors that could benefit from EGFR-targeted therapies. , 2007, Breast.
[43] D Ratner,et al. Cutaneous squamous-cell carcinoma. , 2001, The New England journal of medicine.
[44] E. Wayner,et al. Regulation of human B-cell precursor adhesion to bone marrow stromal cells by cytokines that exert opposing effects on the expression of vascular cell adhesion molecule-1 (VCAM-1). , 1993, Blood.
[45] – Published , 2022 .
[46] J. Huisman. The Netherlands , 1996, The Lancet.
[47] Joe W Gray,et al. Beta1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo. , 2006, Cancer research.
[48] Jeffrey T. Chang,et al. Oncogenic pathway signatures in human cancers as a guide to targeted therapies , 2006, Nature.
[49] J. Rader,et al. Profiling microdissected epithelium and stroma to model genomic signatures for cervical carcinogenesis accommodating for covariates. , 2007, Cancer research.
[50] F. Watt,et al. Different consequences of beta1 integrin deletion in neonatal and adult mouse epidermis reveal a context-dependent role of integrins in regulating proliferation, differentiation, and intercellular communication. , 2005, The Journal of investigative dermatology.
[51] P. Khavari,et al. Epidermal Ras blockade demonstrates spatially localized Ras promotion of proliferation and inhibition of differentiation , 2002, Oncogene.
[52] F. Watt,et al. A tumor-associated β1 integrin mutation that abrogates epithelial differentiation control , 2003, The Journal of cell biology.
[53] Massimo Marchiori,et al. Error and attacktolerance of complex network s , 2004 .
[54] G. Nolan,et al. Transglutaminase 1 delivery to lamellar ichthyosis keratinocytes. , 1996, Human gene therapy.