Modular Analysis of Signal

[1]  Lennart Ljung,et al.  System identification toolbox for use with MATLAB , 1988 .

[2]  Kirsten Jung,et al.  Towards an understanding of the molecular mechanisms of stimulus perception and signal transduction by the KdpD/KdpE system of Escherichia coli. , 2002, Journal of molecular microbiology and biotechnology.

[3]  B. Kholodenko,et al.  Temperature dependence of the epidermal growth factor receptor signaling network can be accounted for by a kinetic model. , 2002, Biochemistry.

[4]  U. Bhalla,et al.  Emergent properties of networks of biological signaling pathways. , 1999, Science.

[5]  J. Ferrell Tripping the switch fantastic: how a protein kinase cascade can convert graded inputs into switch-like outputs. , 1996, Trends in biochemical sciences.

[6]  D. Lauffenburger,et al.  A Computational Study of Feedback Effects on Signal Dynamics in a Mitogen‐Activated Protein Kinase (MAPK) Pathway Model , 2001, Biotechnology progress.

[7]  James E. Ferrell,et al.  Bistability in cell signaling: How to make continuous processes discontinuous, and reversible processes irreversible. , 2001, Chaos.

[8]  G. Tortora,et al.  Anti-epidermal growth factor receptor drugs in cancer therapy , 2002, Expert opinion on investigational drugs.

[9]  Ann M Stock,et al.  Two-component signal transduction. , 2000, Annual review of biochemistry.

[10]  D. Koshland,et al.  An amplified sensitivity arising from covalent modification in biological systems. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[11]  I. H. Segel Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems , 1975 .

[12]  E. Gilles,et al.  The organization of metabolic reaction networks: a signal-oriented approach to cellular models. , 2000, Metabolic engineering.

[13]  D. Lauffenburger,et al.  Bioengineering models of cell signaling. , 2000, Annual review of biomedical engineering.

[14]  E. Gilles,et al.  Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors , 2002, Nature Biotechnology.

[15]  Reinhart Heinrich,et al.  Mathematical models of protein kinase signal transduction. , 2002, Molecular cell.

[16]  J. Ferrell,et al.  A positive-feedback-based bistable ‘memory module’ that governs a cell fate decision , 2003, Nature.

[17]  Julio Saez-Rodriguez,et al.  Dissecting the puzzle of life: modularization of signal transduction networks , 2005, Comput. Chem. Eng..

[18]  Xin Zhao,et al.  Shc‐dependent pathway is redundant but dominant in MAPK cascade activation by EGF receptors: a modeling inference , 2003, FEBS letters.

[19]  D A Lauffenburger,et al.  The role of transient ERK2 signals in fibronectin- and insulin-mediated DNA synthesis. , 2000, Journal of cell science.

[20]  G. Krauss Biochemistry of signal transduction and regulation , 1999 .

[21]  D. Lauffenburger,et al.  Computational modeling of the EGF-receptor system: a paradigm for systems biology. , 2003, Trends in cell biology.

[22]  B. Kholodenko,et al.  Negative feedback and ultrasensitivity can bring about oscillations in the mitogen-activated protein kinase cascades. , 2000, European journal of biochemistry.

[23]  E. Gilles,et al.  The organization of metabolic reaction networks. II. Signal processing in hierarchical structured functional units. , 2001, Metabolic engineering.

[24]  Olaf Wolkenhauer,et al.  Systems Biology: the Reincarnation of Systems Theory Applied in Biology? , 2001, Briefings Bioinform..

[25]  E D Gilles,et al.  Reduction of mathematical models of signal transduction networks: simulation-based approach applied to EGF receptor signalling. , 2004, Systems biology.

[26]  J. S. Parkinson Signal transduction schemes of bacteria , 1993, Cell.

[27]  Ernst Dieter Gilles Network Theory for Chemical Processes , 1998 .

[28]  P. Postma,et al.  Phosphoenolpyruvate:carbohydrate phosphotransferase system of bacteria. , 1985, Microbiological reviews.

[29]  A. Arkin,et al.  Motifs, modules and games in bacteria. , 2003, Current opinion in microbiology.

[30]  J E Ferrell,et al.  How responses get more switch-like as you move down a protein kinase cascade. , 1997, Trends in biochemical sciences.

[31]  H. Schaeffer,et al.  Mitogen-Activated Protein Kinases: Specific Messages from Ubiquitous Messengers , 1999, Molecular and Cellular Biology.

[32]  J. Hopfield,et al.  From molecular to modular cell biology , 1999, Nature.

[33]  Birgit Schoeberl,et al.  Mathematical modeling of signal transduction pathways in mammalian cells at the example of the EGF induced MAP kinase cascade and TNF receptor crosstalk , 2003 .