Effect of metformin treatment on insulin action in diabetic rats: in vivo and in vitro correlations.
暂无分享,去创建一个
R. DeFronzo | G. Shulman | L. Rossetti | R. Gherzi | P. Stein | R. Cordera | G. Andraghetti | G. Falzetti | E. Klein-Robbenhaar
[1] L. Rossetti,et al. Correction of chronic hyperglycemia with vanadate, but not with phlorizin, normalizes in vivo glycogen repletion and in vitro glycogen synthase activity in diabetic skeletal muscle. , 1989, The Journal of clinical investigation.
[2] O. Blondel,et al. Relation of Insulin Deficiency to Impaired Insulin Action in NIDDM Adult Rats Given Streptozocin as Neonates , 1989, Diabetes.
[3] L. Rossetti. Normalization of Insulin Sensitivity With Lithium in Diabetic Rats , 1989, Diabetes.
[4] C. Cobelli,et al. In vivo glucose metabolism in the awake rat: tracer and insulin clamp studies. , 1987, Metabolism: clinical and experimental.
[5] R. Lauro,et al. Regulation of insulin receptor-associated tyrosine kinase by a polyclonal IgG , 1987, Molecular and Cellular Endocrinology.
[6] E. L. Johnson,et al. The protein-tyrosine kinase activity of the insulin receptor is necessary for insulin-mediated receptor down-regulation. , 1987, The Journal of biological chemistry.
[7] G. Shulman,et al. Quantitative analysis of glycogen repletion by nuclear magnetic resonance spectroscopy in the conscious rat. , 1987, The Journal of clinical investigation.
[8] W. Pories,et al. Insulin-Receptor Kinase Activity of Adipose Tissue From Morbidly Obese Humans With and Without NIDDM , 1987, Diabetes.
[9] J. Jaspan,et al. Mechanism of Metformin Action in Non-Insulin-Dependent Diabetes , 1987, Diabetes.
[10] R. DeFronzo,et al. Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats. , 1987, The Journal of clinical investigation.
[11] G. Dohm,et al. Insulin receptor kinase in human skeletal muscle from obese subjects with and without noninsulin dependent diabetes. , 1987, The Journal of clinical investigation.
[12] A. Ullrich,et al. Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin. , 1987, The Journal of biological chemistry.
[13] W. Rutter,et al. Replacement of lysine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin- and antibody-stimulated glucose uptake and receptor kinase activity. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[14] G. Grunberger,et al. Relationship of insulin binding and insulin-stimulated tyrosine kinase activity is altered in type II diabetes. , 1987, The Journal of clinical investigation.
[15] A. Avogaro,et al. Effect of Metformin on Insulin-Stimulated Glucose Turnover and Insulin Binding to Receptors in Type II Diabetes , 1987, Diabetes Care.
[16] H. Klein,et al. Decreased kinase activity of insulin receptors from adipocytes of non-insulin-dependent diabetic subjects. , 1987, The Journal of clinical investigation.
[17] H. Graf,et al. Effect of metformin on peripheral insulin sensitivity in non insulin dependent diabetes mellitus. , 1986, Diabete & metabolisme.
[18] E. Ferrannini,et al. Insulin receptor autophosphorylation and kinase activity in streptozotocin diabetic rats. Effect of a short fast. , 1986, Biochemical and biophysical research communications.
[19] C. Kahn,et al. Autophosphorylation and kinase activity of insulin receptor in diabetic rats. , 1986, The American journal of physiology.
[20] I. G. Fantus,et al. Mechanism of action of metformin: insulin receptor and postreceptor effects in vitro and in vivo. , 1986, The Journal of clinical endocrinology and metabolism.
[21] Bailey Cj,et al. Effect of metformin on glucose metabolism in mouse soleus muscle. , 1986 .
[22] J. Silverman,et al. Studies on the mechanism of insulin resistance in the liver from humans with noninsulin-dependent diabetes. Insulin action and binding in isolated hepatocytes, insulin receptor structure, and kinase activity. , 1986, The Journal of clinical investigation.
[23] W. Rutter,et al. Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose , 1986, Cell.
[24] R. Rizza,et al. Postprandial hyperglycemia in patients with noninsulin-dependent diabetes mellitus. Role of hepatic and extrahepatic tissues. , 1986, The Journal of clinical investigation.
[25] C. Burant,et al. Diabetes-induced functional and structural changes in insulin receptors from rat skeletal muscle. , 1986, The Journal of clinical investigation.
[26] R. Lauro,et al. Inhibition of insulin and epidermal growth factor (EGF) receptor autophosphorylation by a human polyclonal IgG. , 1985, Biochemical and biophysical research communications.
[27] B. Portha,et al. In Vivo Hepatic and Peripheral Insulin Sensitivity in Rats with Non-insulin-dependent Diabetes Induced by Streptozocin: Assessment with the Insulin-Glucose Clamp Technique , 1985, Diabetes.
[28] J. Lord,et al. Postreceptor effect of metformin on insulin action in mice , 1985, The Journal of pharmacy and pharmacology.
[29] H. Klein,et al. Insulin receptor kinase activity in rat liver. Regulation by fasting and high carbohydrate feeding. , 1985, The Journal of biological chemistry.
[30] H. Gin,et al. Metformin improved insulin resistance in type I, insulin-dependent, diabetic patients. , 1985, Metabolism: clinical and experimental.
[31] R. DeFronzo,et al. Hepatic and peripheral insulin resistance following streptozotocin-induced insulin deficiency in the dog. , 1985, Metabolism: clinical and experimental.
[32] A. Study. U.K. Prospective Diabetes Study: II. Reduction in HbA1c with Basal Insulin Supplement, Sulfonylurea, or Biguanide Therapy in Maturity-onset Diabetes , 1985, Diabetes.
[33] R. DeFronzo,et al. Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus. , 1985, The Journal of clinical investigation.
[34] R. Ballotti,et al. Insulin receptor tyrosine kinase is defective in skeletal muscle of insulin-resistant obese mice , 1985, Nature.
[35] C. Kahn,et al. Defect in insulin receptor phosphorylation in erythrocytes and fibroblasts associated with severe insulin resistance. , 1984, The Journal of biological chemistry.
[36] C. Zancanaro,et al. Influence of metformin on metabolic effect of insulin in human adipose tissue in vitro. , 1984, Diabete & metabolisme.
[37] M. Kasuga,et al. Decreased autophosphorylation of the insulin receptor-kinase in streptozotocin-diabetic rats. , 1984, The Journal of biological chemistry.
[38] L. Avioli,et al. Impaired Insulin Action in Rats with Non-insulin-dependent Diabetes , 1984, Diabetes.
[39] S. Lillioja,et al. Correlation between muscle glycogen synthase activity and in vivo insulin action in man. , 1984, The Journal of clinical investigation.
[40] G. Grunberger,et al. Defect in phosphorylation of insulin receptors in cells from an insulin-resistant patient with normal insulin binding. , 1984, Science.
[41] G. Reaven,et al. In vitro insulin resistance of human adipocytes isolated from subjects with noninsulin-dependent diabetes mellitus. , 1983, The Journal of clinical investigation.
[42] R. DeFronzo,et al. New concepts in the pathogenesis and treatment of noninsulin-dependent diabetes mellitus. , 1983, The American journal of medicine.
[43] P. Arner,et al. Postreceptor Defects Causing Insulin Resistance in Normoinsulinemic Non-insulin-dependent Diabetes Mellitus , 1982, Diabetes.
[44] O. Pedersen,et al. Insulin Receptor Binding to Fat and Blood Cells and Insulin Action in Fat Cells from Insulin-dependent Diabetics , 1982, Diabetes.
[45] R. DeFronzo,et al. The Effect of Insulin on the Disposal of Intravenous Glucose: Results from Indirect Calorimetry and Hepatic and Femoral Venous Catheterization , 1981, Diabetes.
[46] J. A. Scarlett,et al. Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus. , 1981, The Journal of clinical investigation.
[47] S. Bonner-Weir,et al. Islet Secretion in a New Experimental Model for Non-insulin-dependent Diabetes , 1981, Diabetes.
[48] L. Mandarino,et al. Dose-response characteristics for effects of insulin on production and utilization of glucose in man. , 1981, The American journal of physiology.
[49] L. Harrison,et al. Purification of the insulin receptor from human placenta by chromatography on immobilized wheat germ lectin and receptor antibody. , 1980, The Journal of biological chemistry.
[50] Hermann Ls. Metformin: a review of its pharmacological properties and therapeutic use. , 1979 .
[51] L. Higginbotham,et al. DOUBLE‐BLIND TRIAL OF METFORMIN IN THE THERAPY OF NONKETOTIC DIABETICS , 1979 .
[52] J. Olefsky,et al. Effects of Streptozotocin-induced Diabetes on Insulin Binding, Glucose Transport, and Intracellular Glucose Metabolism in Isolated Rat Adipocytes , 1979, Diabetes.
[53] B. Portha,et al. Diabetogenic Effect of Streptozotocin in the Rat During the Perinatal Period , 1974, Diabetes.
[54] G. Scatchard,et al. THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS , 1949 .