Apoptosis and plaque destabilization in atherosclerosis: the role of macrophage apoptosis induced by cholesterol

Apoptosis and plaque destabilization in atherosclerosis: the role of macrophage apoptosis induced by cholesterol

[1]  M. Sinensky,et al.  Mechanisms of oxysterol-induced apoptosis , 2001, Current opinion in lipidology.

[2]  P. Libby.  Inflammation in atherosclerosis , 2002, Nature.

[3]  Masataka Mori,et al.  Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes. , 2002, The Journal of clinical investigation.

[4]  I. Tabas.  Mechanisms and Consequences of Cholesterol Loading in Macrophages , 1998 .

[5]  Steven K. Clinton,et al.  The role of macrophages in atherogenesis , 1993 .

[6]  J. Skepper,et al.  Evidence that the death of macrophage foam cells contributes to the lipid core of atheroma. , 1995, Atherosclerosis.

[7]  Robert V Farese,et al.  Increased atherosclerosis in LDL receptor-null mice lacking ACAT1 in macrophages. , 2001, The Journal of clinical investigation.

[8]  F. Urano,et al.  Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. , 2000, Science.

[9]  K. Williams,et al.  The response-to-retention hypothesis of atherogenesis reinforced. , 1998, Current opinion in lipidology.

[10]  M. Brown,et al.  Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis. , 1983, Annual review of biochemistry.

[11]  George Kuriakose,et al.  The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages , 2003, Nature Cell Biology.

[12]  M. Bennett,et al.  Cell death in atherosclerotic plaques , 1996, Current opinion in lipidology.

[13]  D. L. Fry,et al.  Histochemical detection and differentiation of free and esterified cholesterol in swine atherosclerosis using filipin. , 1984, Experimental and molecular pathology.

[14]  Ira Tabas,et al.  Consequences of cellular cholesterol accumulation: basic concepts and physiological implications. , 2002, The Journal of clinical investigation.

[15]  I. Tabas,et al.  Niemann-Pick C heterozygosity confers resistance to lesional necrosis and macrophage apoptosis in murine atherosclerosis , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[16]  P. M. Yao,et al.  Free Cholesterol Loading of Macrophages Is Associated with Widespread Mitochondrial Dysfunction and Activation of the Mitochondrial Apoptosis Pathway* , 2001, The Journal of Biological Chemistry.

[17]  A. Marotta,et al.  Oxidized Low Density Lipoprotein Inhibits Macrophage Apoptosis by Blocking Ceramide Generation, Thereby Maintaining Protein Kinase B Activation and Bcl-XL Levels* , 2003, Journal of Biological Chemistry.

[18]  R. Ross,et al.  Cell biology of atherosclerosis. , 1995, Annual review of physiology.

[19]  W. J. Johnson,et al.  Cell Toxicity Induced by Inhibition of Acyl Coenzyme A:Cholesterol Acyltransferase and Accumulation of Unesterified Cholesterol * , 1995, The Journal of Biological Chemistry.

[20]  D. Sviridov.  Intracellular cholesterol trafficking. , 1999, Histology and histopathology.

[21]  P. M. Yao,et al.  Free Cholesterol Loading of Macrophages Induces Apoptosis Involving the Fas Pathway* , 2000, The Journal of Biological Chemistry.

[22]  I. Tabas,et al.  ABCA1-mediated Cholesterol Efflux Is Defective in Free Cholesterol-loaded Macrophages , 2002, The Journal of Biological Chemistry.

[23]  I. Tabas,et al.  Evidence That the Initial Up-regulation of Phosphatidylcholine Biosynthesis in Free Cholesterol-loaded Macrophages Is an Adaptive Response That Prevents Cholesterol-induced Cellular Necrosis , 1996, The Journal of Biological Chemistry.

[24]  Peter Walter,et al.  Functional and Genomic Analyses Reveal an Essential Coordination between the Unfolded Protein Response and ER-Associated Degradation , 2000, Cell.

[25]  I. Tabas,et al.  Nonoxidative modifications of lipoproteins in atherogenesis. , 1999, Annual review of nutrition.

[26]  G. Evan,et al.  Oxidised lipoproteins may promote inflammation through the selective delay of engulfment but not binding of apoptotic cells by macrophages. , 2003, Atherosclerosis.

[27]  Y. Geng,et al.  Cytotoxic cholesterol is generated by the hydrolysis of cytoplasmic cholesteryl ester and transported to the plasma membrane. , 1999, Atherosclerosis.

[28]  M. Bond,et al.  Physicochemical and histological changes in the arterial wall of nonhuman primates during progression and regression of atherosclerosis. , 1984, The Journal of clinical investigation.

[29]  Junying Yuan,et al.  Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β , 2000, Nature.

[30]  Christopher K. Glass,et al.  Atherosclerosis The Road Ahead , 2001, Cell.