Colon cancer transcriptome.

[1]  Yongsheng Gao,et al.  lncRNA TRPM2-AS Promotes Colorectal Cancer Progression by Regulating miR-22-3p and FSTL1 , 2022, Journal of oncology.

[2]  M. Nasr-Esfahani,et al.  Title: Involvement of unsaturated fatty acid biosynthesis in CRC progression based on in vitro and in silico studies. , 2022, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[3]  B. Ma,et al.  Identification of a Genomic Instability-Related Long Noncoding RNA Prognostic Model in Colorectal Cancer Based on Bioinformatic Analysis , 2022, Disease markers.

[4]  Xiaohui Xu,et al.  The Invasion and Metastasis of Colon Adenocarcinoma (COAD) Induced by SALL4 , 2022, Journal of immunology research.

[5]  Ping Lei,et al.  CD20+CD22+ADAM28+ B Cells in Tertiary Lymphoid Structures Promote Immunotherapy Response , 2022, Frontiers in Immunology.

[6]  C. Shin,et al.  Association between Metabolic Syndrome and the Risk of Colorectal Cancer Diagnosed before 50 years According to Tumor Location. , 2022, Gastroenterology.

[7]  F. Végran,et al.  Role of Cytokines and Chemokines in Angiogenesis in a Tumor Context , 2022, Cancers.

[8]  M. Hong,et al.  Effects of moderate ethanol consumption as a function of n-6:n-3 dietary ratio on lipid profile, inflammation, and liver function in mice , 2022, International journal of cardiology. Cardiovascular risk and prevention.

[9]  Stephanie A. Bien,et al.  Beyond GWAS of Colorectal Cancer: Evidence of Interaction with Alcohol Consumption and Putative Causal Variant for the 10q24.2 Region. , 2022, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[10]  M. Yaspo,et al.  Elevated MACC1 Expression in Colorectal Cancer Is Driven by Chromosomal Instability and Is Associated with Molecular Subtype and Worse Patient Survival , 2022, Cancers.

[11]  Delin Yang,et al.  Prognostic significance of SNCA and its methylation in bladder cancer , 2022, BMC Cancer.

[12]  Xue Bai,et al.  The Cell Cycle-Associated Protein CDKN2A May Promotes Colorectal Cancer Cell Metastasis by Inducing Epithelial-Mesenchymal Transition , 2022, Frontiers in Oncology.

[13]  B. Győrffy,et al.  DNA methylation-based diagnostic, prognostic, and predictive biomarkers in colorectal cancer. , 2022, Biochimica et biophysica acta. Reviews on cancer.

[14]  R. Houlston,et al.  Alcohol consumption, DNA methylation and colorectal cancer risk: Results from pooled cohort studies and Mendelian randomization analysis , 2022, International journal of cancer.

[15]  Hui Guo,et al.  Prognostic significance of SHP2 (PTPN11) expression in solid tumors: A meta-analysis , 2022, PloS one.

[16]  Yuan Yin,et al.  SLCO4A1-AS1 promotes colorectal tumourigenesis by regulating Cdk2/c-Myc signalling , 2022, Journal of Biomedical Science.

[17]  T. Pischon,et al.  Obesity, colorectal cancer and MACC1 expression: A possible novel molecular association , 2022, International Journal of Oncology.

[18]  Wen Zhang,et al.  Coupling of serum CK20 and hyper-methylated CLIP4 as promising biomarker for colorectal cancer diagnosis: from bioinformatics screening to clinical validation , 2021, Aging.

[19]  Bin Wang,et al.  MiR-155-5p suppresses SOX1 to promote proliferation of cholangiocarcinoma via RAF/MEK/ERK pathway , 2021, Cancer cell international.

[20]  P. Brebi,et al.  Novel Methylation Biomarkers for Colorectal Cancer Prognosis , 2021, Biomolecules.

[21]  Shicheng Guo,et al.  Targeted Bisulfite Sequencing Reveals DNA Methylation Changes in Zinc Finger Family Genes Associated With KRAS Mutated Colorectal Cancer , 2021, Frontiers in Cell and Developmental Biology.

[22]  Lan Huang,et al.  SPTBN2, a New Biomarker of Lung Adenocarcinoma , 2021, Frontiers in Oncology.

[23]  Kaitai Zhang,et al.  Exploration of a Novel Prognostic Risk Signature and Its Effect on the Immune Response in Nasopharyngeal Carcinoma , 2021, Frontiers in Oncology.

[24]  Tao Liu,et al.  LINC01605, regulated by the EP300-SMYD2 complex, potentiates the binding between METTL3 and SPTBN2 in colorectal cancer , 2021, Cancer cell international.

[25]  Jianfeng Dai,et al.  Targeting matrix metalloproteinase MMP3 greatly enhances oncolytic virus mediated tumor therapy , 2021, Translational oncology.

[26]  E. Lipke,et al.  Consensus molecular subtype differences linking colon adenocarcinoma and obesity revealed by a cohort transcriptomic analysis , 2021, medRxiv.

[27]  Neha M Jain,et al.  My Cancer Genome: Coevolution of Precision Oncology and a Molecular Oncology Knowledgebase , 2021, JCO clinical cancer informatics.

[28]  Caroline H. Johnson,et al.  Molecular Mechanisms of Alcohol-Induced Colorectal Carcinogenesis , 2021, Cancers.

[29]  T. Werge,et al.  Genetic regulation of spermine oxidase activity and cancer risk: a Mendelian randomization study , 2021, Scientific Reports.

[30]  Jeong-Seok Nam,et al.  Aberrant activation of the CD45-Wnt signaling axis promotes stemness and therapy resistance in colorectal cancer cells , 2021, Theranostics.

[31]  A. Papavassiliou,et al.  Targeting STAT3 Signaling Pathway in Colorectal Cancer , 2021, Biomedicines.

[32]  Zhenchong Li,et al.  SLC39A10 Upregulation Predicts Poor Prognosis, Promotes Proliferation and Migration, and Correlates with Immune Infiltration in Hepatocellular Carcinoma , 2021, Journal of hepatocellular carcinoma.

[33]  B. Ma,et al.  The paradoxical role of matrix metalloproteinase-11 in cancer. , 2021, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[34]  He Zhou,et al.  Expression and prognostic significance of CBX2 in colorectal cancer: database mining for CBX family members in malignancies and vitro analyses , 2021, Cancer cell international.

[35]  Tianming Chen,et al.  Long Non-coding RNA MAFG-AS1 Promotes Cell Proliferation, Migration, and EMT by miR-3196/STRN4 in Drug-Resistant Cells of Liver Cancer , 2021, Frontiers in Cell and Developmental Biology.

[36]  H. Brenner,et al.  Association of Body Mass Index With Risk of Early-Onset Colorectal Cancer: Systematic Review and Meta-Analysis , 2021, The American journal of gastroenterology.

[37]  T. Cai,et al.  Development of a liquid biopsy based purely quantitative digital droplet PCR assay for detection of MLH1 promoter methylation in colorectal cancer patients , 2021, BMC cancer.

[38]  M. Bissonnette,et al.  CXCL12-CXCR4/CXCR7 Axis in Colorectal Cancer: Therapeutic Target in Preclinical and Clinical Studies , 2021, International journal of molecular sciences.

[39]  D. Chan,et al.  Tumour heterogeneity and evolutionary dynamics in colorectal cancer , 2021, Oncogenesis.

[40]  H. Thorlacius,et al.  CXCL2-CXCR2 axis mediates αV integrin-dependent peritoneal metastasis of colon cancer cells , 2021, Clinical & Experimental Metastasis.

[41]  Wei Zhao,et al.  CBX4 Provides an Alternate Mode of Colon Cancer Development via Potential Influences on Circadian Rhythm and Immune Infiltration , 2021, Frontiers in Cell and Developmental Biology.

[42]  G. Sauter,et al.  Diagnostic and prognostic impact of Cytokeratin 19 expression analysis in human tumors: A tissue microarray study of 13,172 tumors. , 2021, Human pathology.

[43]  Nand K. Singh,et al.  Transcriptomic landscape of early age onset of colorectal cancer identifies novel genes and pathways in Indian CRC patients , 2021, Scientific Reports.

[44]  H. Clevers,et al.  NOTUM from Apc-mutant cells biases clonal competition to initiate cancer , 2021, Nature.

[45]  Yuanyuan Ruan,et al.  High PHD Finger Protein 19 (PHF19) expression predicts poor prognosis in colorectal cancer: a retrospective study , 2021, PeerJ.

[46]  R. Nasr,et al.  Methylated circulating tumor DNA as a biomarker for colorectal cancer diagnosis, prognosis, and prediction , 2021, Clinical Epigenetics.

[47]  Guodong Zhao,et al.  Blood leukocytes methylation levels analysis indicate methylated plasma test is a promising tool for colorectal cancer early detection , 2021, Journal of Cancer.

[48]  Jintuan Huang,et al.  NGFR Increases the Chemosensitivity of Colorectal Cancer Cells by Enhancing the Apoptotic and Autophagic Effects of 5-fluorouracil via the Activation of S100A9 , 2021, Frontiers in Oncology.

[49]  T. Hofmann,et al.  The Role of p53 Signaling in Colorectal Cancer , 2021, Cancers.

[50]  Jian-Bing Fan,et al.  Sensitive detection of colorectal cancer in peripheral blood by a novel methylation assay , 2021, Clinical epigenetics.

[51]  Anna Danielewicz,et al.  A Review of Colorectal Cancer in Terms of Epidemiology, Risk Factors, Development, Symptoms and Diagnosis , 2021, Cancers.

[52]  Guangbiao Zhou,et al.  CXCL13 promotes intestinal tumorigenesis through the activation of epithelial AKT signaling. , 2021, Cancer letters.

[53]  K. Matsushima,et al.  Interleukin-11-expressing fibroblasts have a unique gene signature correlated with poor prognosis of colorectal cancer , 2021, Nature Communications.

[54]  Xiaoyuan Song,et al.  RGL2 as an age-dependent factor regulates colon cancer progression , 2021, Computational and structural biotechnology journal.

[55]  A. Długosz,et al.  The Molecular Basis of Alcohol Use Disorder (AUD). Genetics, Epigenetics, and Nutrition in AUD: An Amazing Triangle , 2021, International journal of molecular sciences.

[56]  T. Kalbfleisch,et al.  Long non-coding RNA ZFAS1 is a major regulator of epithelial-mesenchymal transition through miR-200/ZEB1/E-cadherin, vimentin signaling in colon adenocarcinoma , 2021, Cell death discovery.

[57]  Li Liu,et al.  HILPDA Is a Prognostic Biomarker and Correlates With Macrophage Infiltration in Pan-Cancer , 2021, Frontiers in Oncology.

[58]  Ying Cui,et al.  ENC1 Facilitates Colorectal Carcinoma Tumorigenesis and Metastasis via JAK2/STAT5/AKT Axis-Mediated Epithelial Mesenchymal Transition and Stemness , 2021, Frontiers in Cell and Developmental Biology.

[59]  Jie Hong,et al.  CXCL11 Correlates With Antitumor Immunity and an Improved Prognosis in Colon Cancer , 2021, Frontiers in Cell and Developmental Biology.

[60]  Xiufen Zheng,et al.  Circular RNA in colorectal cancer , 2021, Journal of cellular and molecular medicine.

[61]  Haijun Yang,et al.  The methylation of SDC2 and TFPI2 defined three methylator phenotypes of colorectal cancer , 2021, bioRxiv.

[62]  Li Chen,et al.  MMP7 as a potential biomarker of colon cancer and its prognostic value by bioinformatics analysis , 2021, Medicine.

[63]  Matheus C. Bürger,et al.  ETV4 plays a role on the primary events during the adenoma-adenocarcinoma progression in colorectal cancer , 2021, BMC Cancer.

[64]  Yonglian Zhang,et al.  Circ_0082182 promotes oncogenesis and metastasis of colorectal cancer in vitro and in vivo by sponging miR-411 and miR-1205 to activate the Wnt/β-catenin pathway , 2021, World Journal of Surgical Oncology.

[65]  Y. Fujiwara,et al.  AMIGO2 as a novel indicator of liver metastasis in patients with colorectal cancer , 2021, Oncology letters.

[66]  S. Mukherjee,et al.  Exploring the Differential Expression and Prognostic Significance of the COL11A1 Gene in Human Colorectal Carcinoma: An Integrated Bioinformatics Approach , 2021, Frontiers in Genetics.

[67]  M. Sasiadek,et al.  Current Achievements and Applications of Transcriptomics in Personalized Cancer Medicine , 2021, International journal of molecular sciences.

[68]  N. Gao,et al.  Expression and clinical significance of SYNE1 and MAGI2 gene promoter methylation in gastric cancer , 2021, Medicine.

[69]  Huabin Wen,et al.  IRF4 overexpression promotes the transdifferentiation of tregs into macrophage‐like cells to inhibit the development of colon cancer , 2021, Cancer Cell International.

[70]  Yi Liu,et al.  FOSL1 promotes tumorigenesis in colorectal carcinoma by mediating the FBXL2/Wnt/β-catenin axis via Smurf1. , 2021, Pharmacological research.

[71]  Yeming Wang,et al.  Long non-coding RNA COL4A2-AS1 facilitates cell proliferation and glycolysis of colorectal cancer cells via miR-20b-5p/hypoxia inducible factor 1 alpha subunit axis , 2021, Bioengineered.

[72]  S. Barry,et al.  The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer , 2021, Nature Genetics.

[73]  Yufeng Liu,et al.  Prognostic role of DFNA5 in head and neck squamous cell carcinoma revealed by systematic expression analysis , 2020, BMC cancer.

[74]  Ya‐Wen Cheng,et al.  EGFL6 promotes colorectal cancer cell growth and mobility and the anti‐cancer property of anti-EGFL6 antibody , 2020, Cell & Bioscience.

[75]  J. Carethers Racial and ethnic disparities in colorectal cancer incidence and mortality. , 2021, Advances in cancer research.

[76]  Guodong Zhao,et al.  KCNQ5 and C9orf50 Methylation in Stool DNA for Early Detection of Colorectal Cancer , 2021, Frontiers in Oncology.

[77]  Junyan Zhang,et al.  The Clinical Significance and Mechanisms of REG4 in Human Cancers , 2021, Frontiers in Oncology.

[78]  A. Javadmanesh,et al.  A DNA methylation panel for high performance detection of colorectal cancer. , 2020, Cancer genetics.

[79]  B. Vastrad,et al.  Bioinformatics Analysis of Key Genes and Pathways for Obesity Associated Type 2 Diabetes Mellitus as a Therapeutic Target , 2020, bioRxiv.

[80]  Maite Huarte,et al.  Gene regulation by long non-coding RNAs and its biological functions , 2020, Nature reviews. Molecular cell biology.

[81]  Yue-Ming Li,et al.  Long Non-Coding RNAs: The Regulatory Mechanisms, Research Strategies, and Future Directions in Cancers , 2020, Frontiers in Oncology.

[82]  M. Hong,et al.  Effects of low-to-moderate ethanol consumption on colonic growth and gene expression in young adult and middle-aged male rats , 2020, PloS one.

[83]  Kebin Liu,et al.  MS4A1 expression and function in T cells in the colorectal cancer tumor microenvironment. , 2020, Cellular immunology.

[84]  Shuang Zhao,et al.  The Suppressing Effects of Dkk3 Expression on Aggressiveness and Tumorigenesis of Colorectal Cancer , 2020, Frontiers in Oncology.

[85]  Xian Shen,et al.  Long noncoding RNAs: functions and mechanisms in colon cancer , 2020, Molecular Cancer.

[86]  Yuanting Gu,et al.  Circ_0008039 supports breast cancer cell proliferation, migration, invasion, and glycolysis by regulating the miR‐140‐3p/SKA2 axis , 2020, Molecular oncology.

[87]  M. Wei,et al.  Long non-coding RNA ZFAS1 promotes colorectal cancer tumorigenesis and development through DDX21-POLR1B regulatory axis , 2020, Aging.

[88]  D. Sahoo,et al.  The PVT1 lncRNA is a novel epigenetic enhancer of MYC, and a promising risk-stratification biomarker in colorectal cancer , 2020, Molecular cancer.

[89]  I. Baranowska-Bosiacka,et al.  CC Chemokines in a Tumor: A Review of Pro-Cancer and Anti-Cancer Properties of the Ligands of Receptors CCR1, CCR2, CCR3, and CCR4 , 2020, International journal of molecular sciences.

[90]  Y. Shu,et al.  Functional genetic variant of HSD17B12 in the fatty acid biosynthesis pathway predicts the outcome of colorectal cancer , 2020, Journal of cellular and molecular medicine.

[91]  Xiaozhou He,et al.  Hypoxia-induced circCCDC66 promotes the tumorigenesis of colorectal cancer via the miR-3140/autophagy pathway , 2020, International journal of molecular medicine.

[92]  Aosi Xie,et al.  INHBB Is a Novel Prognostic Biomarker Associated with Cancer-Promoting Pathways in Colorectal Cancer , 2020, BioMed research international.

[93]  F. Skorpen,et al.  DNA methylation markers detected in blood, stool, urine, and tissue in colorectal cancer: a systematic review of paired samples , 2020, International Journal of Colorectal Disease.

[94]  Jing Zhao,et al.  Blocking MAPK/ERK pathway sensitizes hepatocellular carcinoma cells to temozolomide via downregulating MGMT expression , 2020, Annals of translational medicine.

[95]  Bowen Yu,et al.  The long noncoding RNA LUCAT1 promotes colorectal cancer cell proliferation by antagonizing Nucleolin to regulate MYC expression , 2020, Cell Death & Disease.

[96]  M. Herlyn,et al.  Inhibiting insulin and mTOR signaling by afatinib and crizotinib combination fosters broad cytotoxic effects in cutaneous malignant melanoma , 2020, Cell Death & Disease.

[97]  M. Abbaszadegan,et al.  Mechanisms of long non‐coding RNA function in colorectal cancer tumorigenesis , 2020, Asia-Pacific journal of clinical oncology.

[98]  G. Martinelli,et al.  A WEE1 family business: regulation of mitosis, cancer progression, and therapeutic target , 2020, Journal of Hematology & Oncology.

[99]  G. Kang,et al.  SMOC2, an intestinal stem cell marker, is an independent prognostic marker associated with better survival in colorectal cancers , 2020, Scientific Reports.

[100]  E. Bellolio,et al.  Landscape of Genome-Wide DNA Methylation of Colorectal Cancer Metastasis , 2020, Cancers.

[101]  A. Kulczyńska-Przybik,et al.  The Significance of CXCL1 and CXCL8 as Well as Their Specific Receptors in Colorectal Cancer , 2020, Cancer management and research.

[102]  C. Wan,et al.  Transcriptional Regulation of Wnt/β-Catenin Pathway in Colorectal Cancer , 2020, Cells.

[103]  Alok Kumar,et al.  IGFBP3 gene promoter methylation analysis and its association with clinicopathological characteristics of colorectal carcinoma , 2020, Molecular Biology Reports.

[104]  Jun Yu,et al.  EZH2 regulates sFRP4 expression without affecting the methylation of sFRP4 promoter DNA in colorectal cancer cell lines , 2020, Experimental and therapeutic medicine.

[105]  Yanxiang Cheng,et al.  TMEM206 is a potential prognostic marker of hepatocellular carcinoma , 2020, Oncology letters.

[106]  M. Lauriola,et al.  Roles of IL-1 in Cancer: From Tumor Progression to Resistance to Targeted Therapies , 2020, International journal of molecular sciences.

[107]  Liangcai Zhao,et al.  S100A2 promotes glycolysis and proliferation via GLUT1 regulation in colorectal cancer , 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[108]  Wei-Dong Chen,et al.  Emerging Roles of Wnt Ligands in Human Colorectal Cancer , 2020, Frontiers in Oncology.

[109]  P. Schrotz-King,et al.  Fecal DNA methylation markers for detecting stages of colorectal cancer and its precursors: a systematic review , 2020, Clinical Epigenetics.

[110]  Kevin A. Henry,et al.  Residential Mobility and Geospatial Disparities in Colon Cancer Survival , 2020, Cancer Epidemiology, Biomarkers & Prevention.

[111]  N. Hempel,et al.  Extracellular Glutathione Peroxidase GPx3 and Its Role in Cancer , 2020, Cancers.

[112]  Y. Shih,et al.  Epigenetic Silencing of LMX1A Contributes to Cancer Progression in Lung Cancer Cells , 2020, International journal of molecular sciences.

[113]  Xianyong Lan,et al.  Mir-193b Regulates the Differentiation, Proliferation, and Apoptosis of Bovine Adipose Cells by Targeting the ACSS2/AKT Axis , 2020, Animals : an open access journal from MDPI.

[114]  Yulong He,et al.  Long non-coding RNA H19 promotes colorectal cancer metastasis via binding to hnRNPA2B1 , 2020, Journal of Experimental & Clinical Cancer Research.

[115]  N. Habermann,et al.  Multi-omics Analysis Reveals Adipose–tumor Crosstalk in Patients with Colorectal Cancer , 2020, Cancer Prevention Research.

[116]  Xuehao Wang,et al.  Hypoxia‐induced hsa_circ_0000826 is linked to liver metastasis of colorectal cancer , 2020, Journal of clinical laboratory analysis.

[117]  M. Kerachian,et al.  Role of aldo‐keto reductase family 1 member B1 (AKR1B1) in the cancer process and its therapeutic potential , 2020, Journal of cellular and molecular medicine.

[118]  A. Masotti,et al.  Integrated Transcriptome Analysis of Human Visceral Adipocytes Unravels Dysregulated microRNA-Long Non-coding RNA-mRNA Networks in Obesity and Colorectal Cancer , 2020, Frontiers in Oncology.

[119]  Ziyou Lin,et al.  RETRACTED ARTICLE: Upregulation of OSBPL3 by HIF1A promotes colorectal cancer progression through activation of RAS signaling pathway , 2020, Cell Death & Disease.

[120]  Y. Shih,et al.  NKX6.1 Represses Tumorigenesis, Metastasis, and Chemoresistance in Colorectal Cancer , 2020, International journal of molecular sciences.

[121]  W. Xiong,et al.  Long noncoding RNA EPB41L4A‐AS1 functions as an oncogene by regulating the Rho/ROCK pathway in colorectal cancer , 2020, Journal of cellular physiology.

[122]  Minying Zheng,et al.  Structure and function of Septin 9 and its role in human malignant tumors , 2020, World journal of gastrointestinal oncology.

[123]  F. Casanueva,et al.  Association between variation of circulating 25-OH vitamin D and methylation of secreted frizzled-related protein 2 in colorectal cancer , 2020, Clinical Epigenetics.

[124]  A. Archer,et al.  High-fat diet impacts the colon and its transcriptome in a sex-dependent manner that is modifiable by estrogens , 2020, bioRxiv.

[125]  W. Freeman,et al.  Opposite Roles of the JMJD1A Interaction Partners MDFI and MDFIC in Colorectal Cancer , 2020, Scientific Reports.

[126]  Ziyuan Guo,et al.  Circular RNAs in the pathogenesis of atherosclerosis. , 2020, Life sciences.

[127]  B. O’Rourke,et al.  Nuclear-mitochondrial communication involving miR-181c plays an important role in cardiac dysfunction during obesity. , 2020, Journal of molecular and cellular cardiology.

[128]  Zhirong Wang,et al.  LINC02418 promotes colon cancer progression by suppressing apoptosis via interaction with miR-34b-5p/BCL2 axis , 2020, Cancer cell international.

[129]  R. Verma,et al.  ETS1 Suppresses Tumorigenesis of Human Breast Cancer via Trans-Activation of Canonical Tumor Suppressor Genes , 2020, Frontiers in Oncology.

[130]  Yajun Xiao,et al.  Activation of BDNF/TrkB pathway promotes prostate cancer progression via induction of epithelial‐mesenchymal transition and anoikis resistance , 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[131]  M. Dozmorov,et al.  IGFBP-3/IGFBP-3 Receptor System as an Anti-Tumor and Anti-Metastatic Signaling in Cancer , 2020, Cells.

[132]  N. Halama,et al.  Evaluation of the inflammatory markers CCL8, CXCL5, and LIF in patients with anastomotic leakage after colorectal cancer surgery , 2020, International Journal of Colorectal Disease.

[133]  Hua Mao,et al.  ARNTL2 knockdown suppressed the invasion and migration of colon carcinoma: decreased SMOC2-EMT expression through inactivation of PI3K/AKT pathway. , 2020, American journal of translational research.

[134]  Shanshan Zhao,et al.  TFPI2 suppresses breast cancer progression through inhibiting TWIST-integrin α5 pathway , 2020, Molecular medicine.

[135]  W. Fan,et al.  Whole-transcriptome analysis reveals a potential hsa_circ_0001955/hsa_circ_0000977-mediated miRNA-mRNA regulatory sub-network in colorectal cancer , 2020, Aging.

[136]  Xiaobo Fan,et al.  lncRNA PVT1 Promotes Tumorigenesis of Colorectal Cancer by Stabilizing miR-16-5p and Interacting with the VEGFA/VEGFR1/AKT Axis , 2020, Molecular therapy. Nucleic acids.

[137]  Shanshan Liu,et al.  MicroRNAs Associated With Colon Cancer: New Potential Prognostic Markers and Targets for Therapy , 2020, Frontiers in Bioengineering and Biotechnology.

[138]  Qingqiang Yang,et al.  CDK1 and CDC20 overexpression in patients with colorectal cancer are associated with poor prognosis: evidence from integrated bioinformatics analysis , 2020, World Journal of Surgical Oncology.

[139]  M. Zaiou circRNAs Signature as Potential Diagnostic and Prognostic Biomarker for Diabetes Mellitus and Related Cardiovascular Complications , 2020, Cells.

[140]  V. Constâncio,et al.  DNA Methylation-Based Testing in Liquid Biopsies as Detection and Prognostic Biomarkers for the Four Major Cancer Types , 2020, Cells.

[141]  C. Guillemette,et al.  Emerging roles for UDP-glucuronosyltransferases in drug resistance and cancer progression , 2020, British Journal of Cancer.

[142]  Shukui Wang,et al.  Circular RNAs: The crucial regulatory molecules in colorectal cancer. , 2020, Pathology, research and practice.

[143]  Xuejun Sun,et al.  Knockdown of MMP-1 inhibits the progression of colorectal cancer by suppressing the PI3K/Akt/c-myc signaling pathway and EMT , 2020, Oncology Reports.

[144]  Yangxian Xu,et al.  Comprehensive RNA Sequencing in Adenoma-Cancer Transition Identified Predictive Biomarkers and Therapeutic Targets of Human CRC , 2020, Molecular therapy. Nucleic acids.

[145]  G-R Zhou,et al.  LncRNA MIR4435-2HG contributes into colorectal cancer development and predicts poor prognosis. , 2020, European review for medical and pharmacological sciences.

[146]  Monjur Ahmed Colon Cancer: A Clinician’s Perspective in 2019 , 2020, Gastroenterology research.

[147]  Ye Xu,et al.  FOXE1 represses cell proliferation and Warburg effect by inhibiting HK2 in colorectal cancer , 2020, Cell Communication and Signaling.

[148]  Y. Ba,et al.  Exosome‐delivered circRNA promotes glycolysis to induce chemoresistance through the miR‐122‐PKM2 axis in colorectal cancer , 2020, Molecular oncology.

[149]  A. Goel,et al.  Epigenetics of colorectal cancer: biomarker and therapeutic potential , 2020, Nature Reviews Gastroenterology & Hepatology.

[150]  Junwen Ma,et al.  LINC02163 promotes colorectal cancer progression via miR-511-3p/AKT3 axis , 2020, Artificial cells, nanomedicine, and biotechnology.

[151]  B. Mroczko,et al.  Chemokines—What Is Their Role in Colorectal Cancer? , 2020, Cancer control : journal of the Moffitt Cancer Center.

[152]  Lianghong Zheng,et al.  Circulating tumor DNA methylation profiles enable early diagnosis, prognosis prediction, and screening for colorectal cancer , 2020, Science Translational Medicine.

[153]  Wei Xu,et al.  Circulating lncRNA SNHG11 as a novel biomarker for early diagnosis and prognosis of colorectal cancer , 2020, International journal of cancer.

[154]  Ming Liu,et al.  Circular RNA hsa_circ_0053277 promotes the development of colorectal cancer by upregulating matrix metallopeptidase 14 via miR‐2467‐3p sequestration , 2020, Journal of cellular physiology.

[155]  D. Xie,et al.  circCAMSAP1 Promotes Tumor Growth in Colorectal Cancer via the miR-328-5p/E2F1 Axis. , 2019, Molecular therapy : the journal of the American Society of Gene Therapy.

[156]  Jie Guo,et al.  Role of Regenerating Islet-Derived Protein 3A in Gastrointestinal Cancer , 2019, Front. Oncol..

[157]  Ye Liu,et al.  Interleukin-24 Regulates T Cell Activity in Patients With Colorectal Adenocarcinoma , 2019, Front. Oncol..

[158]  Jianxin Wang,et al.  Long Non-Coding RNA TTN-AS1 Promotes the Proliferation and Invasion of Colorectal Cancer Cells by Activating miR-497-Mediated PI3K/Akt/mTOR Signaling , 2019, OncoTargets and therapy.

[159]  Bin Zhang,et al.  m6A modification-mediated CBX8 induction regulates stemness and chemosensitivity of colon cancer via upregulation of LGR5 , 2019, Molecular Cancer.

[160]  Yashuang Zhao,et al.  DNA methylation of SFRP1, SFRP2, and WIF1 and prognosis of postoperative colorectal cancer patients , 2019, BMC Cancer.

[161]  N. Lin,et al.  Circ_0001955 facilitates hepatocellular carcinoma (HCC) tumorigenesis by sponging miR-516a-5p to release TRAF6 and MAPK11 , 2019, Cell Death & Disease.

[162]  F. Jiang,et al.  LINC01413/hnRNP-K/ZEB1 Axis Accelerates Cell Proliferation and EMT in Colorectal Cancer via Inducing YAP1/TAZ1 Translocation , 2019, Molecular therapy. Nucleic acids.

[163]  C. Andersen,et al.  DAPK1 loss triggers tumor invasion in colorectal tumor cells , 2019, Cell Death & Disease.

[164]  Takaaki Masuda,et al.  GTF2IRD1 on chromosome 7 is a novel oncogene regulating the tumor‐suppressor gene TGFβR2 in colorectal cancer , 2019, Cancer science.

[165]  Yongchao Li,et al.  A Novel circFMN2 Promotes Tumor Proliferation in CRC by Regulating the miR-1182/hTERT Signaling Pathways. , 2019, Clinical science.

[166]  H. Nielsen,et al.  Novel DNA methylation biomarkers show high sensitivity and specificity for blood-based detection of colorectal cancer—a clinical biomarker discovery and validation study , 2019, Clinical Epigenetics.

[167]  Hui Wang,et al.  High-Yield Methylation Markers for Stool-Based Detection of Colorectal Cancer , 2019, Digestive Diseases and Sciences.

[168]  X. Zhi,et al.  Syndecan-2 in colorectal cancer plays oncogenic role via epithelial-mesenchymal transition and MAPK pathway. , 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[169]  Lili Li,et al.  Hub Genes and Key Pathway Identification in Colorectal Cancer Based on Bioinformatic Analysis , 2019, BioMed research international.

[170]  I. Csabai,et al.  Genome-wide expression profiling in colorectal cancer focusing on lncRNAs in the adenoma-carcinoma transition , 2019, BMC Cancer.

[171]  G. Ferbeyre,et al.  NFE2L3 Controls Colon Cancer Cell Growth through Regulation of DUX4, a CDK1 Inhibitor. , 2019, Cell reports.

[172]  Zhenming Zhang,et al.  Circular RNA hsa_circ_0001178 facilitates the invasion and metastasis of colorectal cancer through upregulating ZEB1 via sponging multiple miRNAs , 2019, Biological chemistry.

[173]  J. Böhm,et al.  Transcriptome profiling of adipose tissue reveals depot-specific metabolic alterations among colorectal cancer patients. , 2019, The Journal of clinical endocrinology and metabolism.

[174]  W. Geng,et al.  BMP3 suppresses colon tumorigenesis via ActRIIB/SMAD2-dependent and TAK1/JNK signaling pathways , 2019, Journal of Experimental & Clinical Cancer Research.

[175]  B. Xiao,et al.  Plasma circular RNA panel acts as a novel diagnostic biomarker for colorectal cancer. , 2019, Clinical biochemistry.

[176]  Chiu-Hsieh Hsu,et al.  Kallikrein 6 protease advances colon tumorigenesis via induction of the high mobility group A2 protein , 2019, Oncotarget.

[177]  E. Lacunza,et al.  Variations in AXIN2 predict risk and prognosis of colorectal cancer , 2019, BDJ Open.

[178]  Jie-Wei Chen,et al.  N6-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis , 2019, Nature Communications.

[179]  G. Luo,et al.  DNA methylation detection methods used in colorectal cancer , 2019, World journal of clinical cases.

[180]  Qiang Tian,et al.  SEPT9_i1 regulates human breast cancer cell motility through cytoskeletal and RhoA/FAK signaling pathway regulation , 2019, Cell Death & Disease.

[181]  Y. Shih,et al.  A Novel Prognostic DNA Methylation Panel for Colorectal Cancer , 2019, International journal of molecular sciences.

[182]  Guo-tian Ruan,et al.  Diagnostic and prognostic values of C-X-C motif chemokine ligand 3 in patients with colon cancer , 2019, Oncology reports.

[183]  Xi-lin Zhang,et al.  Two Novel Long Noncoding RNAs – RP11-296E3.2 and LEF1-AS1can – Separately Serve as Diagnostic and Prognostic Bio-Markers of Metastasis in Colorectal Cancer , 2019, Medical science monitor : international medical journal of experimental and clinical research.

[184]  J. Behrens,et al.  An aggregon in conductin/axin2 regulates Wnt/β-catenin signaling and holds potential for cancer therapy , 2019, Nature Communications.

[185]  Fei Liao,et al.  Homo Sapiens Circular RNA 0079993 (hsa_circ_0079993) of the POLR2J4 Gene Acts as an Oncogene in Colorectal Cancer Through the microRNA-203a-3p.1 and CREB1 Axis , 2019, Medical science monitor : international medical journal of experimental and clinical research.

[186]  B. Jia,et al.  FBXW7 circular RNA regulates proliferation, migration and invasion of colorectal carcinoma through NEK2, mTOR, and PTEN signaling pathways in vitro and in vivo , 2019, BMC Cancer.

[187]  T. Ozawa,et al.  Angiotensin I-converting enzyme inhibitors/angiotensin II receptor blockers may reduce tumor recurrence in left-sided and early colorectal cancers , 2019, International Journal of Colorectal Disease.

[188]  W. Jia,et al.  A circRNA signature predicts postoperative recurrence in stage II/III colon cancer , 2019, EMBO molecular medicine.

[189]  B. Negahdari,et al.  Targeting siRNA in colorectal cancer therapy: Nanotechnology comes into view , 2019, Journal of cellular physiology.

[190]  Yalun Li,et al.  Identification of differentially expressed genes and biological characteristics of colorectal cancer by integrated bioinformatics analysis , 2019, Journal of cellular physiology.

[191]  Z. Fang,et al.  Knockdown of KLK12 inhibits viability and induces apoptosis in human colorectal cancer HT-29 cell line , 2019, International journal of molecular medicine.

[192]  Wen Xu,et al.  Small nucleolar RNA host gene 1 promotes development and progression of colorectal cancer through negative regulation of miR‐137 , 2019, Molecular carcinogenesis.

[193]  Siwei Wang,et al.  Cancer-associated fibroblasts: an emerging target of anti-cancer immunotherapy , 2019, Journal of Hematology & Oncology.

[194]  J. Qian,et al.  Profiling the lncRNA-miRNA-mRNA ceRNA network to reveal potential crosstalk between inflammatory bowel disease and colorectal cancer , 2019, PeerJ.

[195]  Zhengyang Feng,et al.  Identification of microRNA‐181 as a promising biomarker for predicting the poor survival in colorectal cancer , 2019, Cancer medicine.

[196]  Xiaodong Jin,et al.  CircRNA CBL.11 suppresses cell proliferation by sponging miR-6778-5p in colorectal cancer , 2019, BMC Cancer.

[197]  D. Sahoo,et al.  miR-221 targets QKI to enhance the tumorigenic capacity of human colorectal cancer stem cells. , 2019, Cancer research.

[198]  S. Varambally,et al.  MTHFD1L, A Folate Cycle Enzyme, Is Involved in Progression of Colorectal Cancer☆☆☆ , 2019, Translational oncology.

[199]  Mei Han,et al.  Expression of circZNF609 is Down-Regulated in Colorectal Cancer Tissue and Promotes Apoptosis in Colorectal Cancer Cells by Upregulating p53 , 2019, Medical science monitor : international medical journal of experimental and clinical research.

[200]  Matthew S Macauley,et al.  Coordinated roles for glycans in regulating the inhibitory function of CD22 on B cells , 2019, Biomedical journal.

[201]  Ye Xu,et al.  Overexpression of CASC19 indicates poor prognosis and facilitates proliferation, migration and invasion in colorectal cancer , 2019, Translational cancer research.

[202]  J. Gaedcke,et al.  Epigenome Mapping Identifies Tumor-Specific Gene Expression in Primary Rectal Cancer , 2019, Cancers.

[203]  Adel Derghal,et al.  MicroRNAs in Obesity and Related Metabolic Disorders , 2019, Cells.

[204]  A. Maugeri,et al.  Epigenetic Biomarkers in Colorectal Cancer Patients Receiving Adjuvant or Neoadjuvant Therapy: A Systematic Review of Epidemiological Studies , 2019, International journal of molecular sciences.

[205]  H. Choudhry,et al.  Roles of long non-coding RNAs in colorectal cancer tumorigenesis: A Review. , 2019, Molecular and clinical oncology.

[206]  L. Du,et al.  Long noncoding RNA LINC02418 regulates MELK expression by acting as a ceRNA and may serve as a diagnostic marker for colorectal cancer , 2019, Cell Death & Disease.

[207]  A. Liebert,et al.  Transcriptome analysis identifies a robust gene expression program in the mouse intestinal epithelium on aging , 2019, Scientific Reports.

[208]  Jakob Nikolas Kather,et al.  CCR5 status and metastatic progression in colorectal cancer , 2019, Oncoimmunology.

[209]  L. Gentilucci,et al.  Novel Ligands Targeting α4β1 Integrin: Therapeutic Applications and Perspectives , 2019, Front. Chem..

[210]  B. Győrffy,et al.  Low level of exosomal long non-coding RNA HOTTIP is a prognostic biomarker in colorectal cancer , 2019, RNA biology.

[211]  X. Zhi,et al.  Withdrawn: circLgr4 drives colorectal tumorigenesis and invasion through Lgr4‐targeting peptide , 2019, International journal of cancer.

[212]  Zhong Zhou,et al.  CircACC1 Regulates Assembly and Activation of AMPK Complex under Metabolic Stress. , 2019, Cell metabolism.

[213]  Xiaoping Yang,et al.  Circular RNA hsa_circRNA_102958 promotes tumorigenesis of colorectal cancer via miR-585/CDC25B axis , 2019, Cancer management and research.

[214]  S. Cai,et al.  Circ-ITGA7 sponges miR-3187-3p to upregulate ASXL1, suppressing colorectal cancer proliferation , 2019, Cancer management and research.

[215]  C. Bassi,et al.  Methylation Dynamics of RASSF1A and Its Impact on Cancer , 2019, Cancers.

[216]  Jakob Nikolas Kather,et al.  Aryl hydrocarbon receptor nuclear translocator-like (ARNTL/BMAL1) is associated with bevacizumab resistance in colorectal cancer via regulation of vascular endothelial growth factor A , 2019, EBioMedicine.

[217]  Chang-li Zhu,et al.  Circular RNA hsa_circ_0007142 Is Upregulated and Targets miR-103a-2-5p in Colorectal Cancer , 2019, Journal of oncology.

[218]  Xian‐Man Zhang,et al.  Obesity-associated, but not obesity-independent, tumors respond to insulin by increasing mitochondrial glucose oxidation , 2019, PloS one.

[219]  Lingyun Zheng,et al.  Activation of Slit2/Robo1 Signaling Promotes Tumor Metastasis in Colorectal Carcinoma through Activation of the TGF-β/Smads Pathway , 2019, Cells.

[220]  Yue Hu,et al.  Clinical value of MLH1-negative circulating tumor cells in lung cancer patients , 2019, Medicine.

[221]  Hong Yu,et al.  MicroRNA-193a-3p suppresses the colorectal cancer cell proliferation and progression through downregulating the PLAU expression , 2019, Cancer management and research.

[222]  Mingyao Liu,et al.  Diet-induced obese alters the expression and function of hepatic drug-metabolizing enzymes and transporters in rats. , 2019, Biochemical pharmacology.

[223]  F. Zhou,et al.  Overexpression of CEP72 Promotes Bladder Urothelial Carcinoma Cell Aggressiveness via Epigenetic CREB-Mediated Induction of SERPINE1. , 2019, The American journal of pathology.

[224]  Yueming Sun,et al.  Long noncoding RNA Linc02023 regulates PTEN stability and suppresses tumorigenesis of colorectal cancer in a PTEN-dependent pathway. , 2019, Cancer letters.

[225]  R. Liu,et al.  Emerging roles of circular RNAs in colorectal cancer , 2019, OncoTargets and therapy.

[226]  Wen-Wei Hu,et al.  Hsa_circ_0009361 acts as the sponge of miR-582 to suppress colorectal cancer progression by regulating APC2 expression. , 2019, Clinical science.

[227]  T. Bertero,et al.  Inhibition of CHK1 (Checkpoint Kinase 1) Elicits Therapeutic Effects in Pulmonary Arterial Hypertension. , 2019, Arteriosclerosis, thrombosis, and vascular biology.

[228]  Zhongmiao Wang,et al.  Circular RNA PVT1 promotes metastasis via miR-145 sponging in CRC. , 2019, Biochemical and biophysical research communications.

[229]  Hui Zhi,et al.  LncRNA BDNF‐AS suppresses colorectal cancer cell proliferation and migration by epigenetically repressing GSK‐3β expression , 2019, Cell biochemistry and function.

[230]  Yao Liu,et al.  NSD2 circular RNA promotes metastasis of colorectal cancer by targeting miR‐199b‐5p‐mediated DDR1 and JAG1 signalling , 2019, The Journal of pathology.

[231]  Maite Huarte,et al.  SNHG15 is a bifunctional MYC-regulated noncoding locus encoding a lncRNA that promotes cell proliferation, invasion and drug resistance in colorectal cancer by interacting with AIF , 2019, Journal of Experimental & Clinical Cancer Research.

[232]  Jinshui Zhu,et al.  miR-1271 enhances the sensitivity of colorectal cancer cells to cisplatin , 2019, Experimental and therapeutic medicine.

[233]  Wenjun Chang,et al.  Low tumour PPM1H indicates poor prognosis in colorectal cancer via activation of cancer-associated fibroblasts , 2019, British Journal of Cancer.

[234]  Jian Lu,et al.  Functional role of long non-coding RNA CASC19/miR-140-5p/CEMIP axis in colorectal cancer progression in vitro , 2019, World journal of gastroenterology.

[235]  R. Sanz-Pamplona,et al.  Noncanonical TGFβ Pathway Relieves the Blockade of IL1β/TGFβ-Mediated Crosstalk between Tumor and Stroma: TGFBR1 and TAK1 Inhibition in Colorectal Cancer , 2019, Clinical Cancer Research.

[236]  Hanshao Liu,et al.  A pilot study of new promising non-coding RNA diagnostic biomarkers for early-stage colorectal cancers , 2019, Clinical chemistry and laboratory medicine.

[237]  Yanling Li,et al.  Long non-coding RNA SNHG16 affects cell proliferation and predicts a poor prognosis in patients with colorectal cancer via sponging miR-200a-3p , 2019, Bioscience reports.

[238]  Yuan Yang,et al.  EYA4 serves as a prognostic biomarker in hepatocellular carcinoma and suppresses tumour angiogenesis and metastasis , 2019, Journal of cellular and molecular medicine.

[239]  Xiang-Nan Li,et al.  Circular RNA circVAPA is up-regulated and exerts oncogenic properties by sponging miR-101 in colorectal cancer. , 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[240]  Matthew D. Dun,et al.  Cell-Free DNA as a Diagnostic Blood-Based Biomarker for Colorectal Cancer: A Systematic Review. , 2019, Journal of Surgical Research.

[241]  Qi Zhou,et al.  A novel protein encoded by a circular RNA circPPP1R12A promotes tumor pathogenesis and metastasis of colon cancer via Hippo-YAP signaling , 2019, Molecular Cancer.

[242]  Hongmei Zhang,et al.  Activation of CXCL6/CXCR1/2 Axis Promotes the Growth and Metastasis of Osteosarcoma Cells in vitro and in vivo , 2019, Front. Pharmacol..

[243]  Jingxia Li,et al.  Autophagy-mediated Mir6981 degradation exhibits CDKN1B promotion of PHLPP1 protein translation , 2019, Autophagy.

[244]  W. Leung,et al.  Roles of Methylated DNA Biomarkers in Patients with Colorectal Cancer , 2019, Disease markers.

[245]  Huaiming Wang,et al.  CircRNA_104916 regulates migration, apoptosis and epithelial-mesenchymal transition in colon cancer cells. , 2019, Frontiers in bioscience.

[246]  M. Guan,et al.  Circular RNA circ_0002138 is down-regulated and suppresses cell proliferation in colorectal cancer. , 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[247]  Hui Tang,et al.  IL1A polymorphisms is a risk factor for colorectal cancer in Chinese Han population: a case control study , 2019, BMC Cancer.

[248]  Zhenggang Zhu,et al.  Oncostatin M receptor, positively regulated by SP1, promotes gastric cancer growth and metastasis upon treatment with Oncostatin M , 2019, Gastric Cancer.

[249]  Haoyu Wu,et al.  STK33/ERK2 signal pathway contribute the tumorigenesis of colorectal cancer HCT15 cells , 2019, Bioscience reports.

[250]  Olga Babosova,et al.  Msx1 loss suppresses formation of the ectopic crypts developed in the Apc-deficient small intestinal epithelium , 2019, Scientific Reports.

[251]  Zhuo-wei Hu,et al.  TRIB3 Interacts With β-Catenin and TCF4 to Increase Stem Cell Features of Colorectal Cancer Stem Cells and Tumorigenesis. , 2019, Gastroenterology.

[252]  M. Ramachandran,et al.  A review on role of ATM gene in hereditary transfer of colorectal cancer , 2019, Acta bio-medica : Atenei Parmensis.

[253]  Jeffrey S. Morris,et al.  Circulating inflammation signature predicts overall survival and relapse-free survival in metastatic colorectal cancer , 2019, British Journal of Cancer.

[254]  T. Hay,et al.  APC2 is critical for ovarian WNT signalling control, fertility and tumour suppression , 2019, BMC Cancer.

[255]  Yuhong Wang,et al.  HMGA1 in cancer: Cancer classification by location , 2019, Journal of cellular and molecular medicine.

[256]  Hongxia Zhu,et al.  Emerging microRNA biomarkers for colorectal cancer diagnosis and prognosis , 2019, Royal Society Open Biology.

[257]  Qingyuan Li,et al.  LncRNA SNHG6 promotes proliferation, invasion and migration in colorectal cancer cells by activating TGF-β/Smad signaling pathway via targeting UPF1 and inducing EMT via regulation of ZEB1 , 2019, International journal of medical sciences.

[258]  Tao Mao,et al.  Has_circ_0055625 from circRNA profile increases colon cancer cell growth by sponging miR‐106b‐5p , 2018, Journal of cellular biochemistry.

[259]  Yangyang Chen,et al.  Molecular mechanism of LKB1 in the invasion and metastasis of colorectal cancer. , 2018, Oncology reports.

[260]  The UniProt Consortium,et al.  UniProt: a worldwide hub of protein knowledge , 2018, Nucleic Acids Res..

[261]  Linbo Liu,et al.  Hsa_circ_0136666 promotes the proliferation and invasion of colorectal cancer through miR‐136/SH2B1 axis , 2018, Journal of cellular physiology.

[262]  W. Cui,et al.  circCDYL/microRNA-150-5p participates in modulating growth and migration of colon cancer cells , 2019, General physiology and biophysics.

[263]  F. Wang,et al.  A systematic review and quantitative assessment of methylation biomarkers in fecal DNA and colorectal cancer and its precursor, colorectal adenoma. , 2019, Mutation research.

[264]  M. Kerachian,et al.  Long interspersed nucleotide element-1 (LINE-1) methylation in colorectal cancer. , 2019, Clinica chimica acta; international journal of clinical chemistry.

[265]  Hanchen Xu,et al.  RNA-Seq profiling of circular RNAs in human colorectal Cancer liver metastasis and the potential biomarkers , 2019, Molecular Cancer.

[266]  Xue-qun Ren,et al.  Identification of a 6-gene signature predicting prognosis for colorectal cancer , 2019, Cancer Cell International.

[267]  F. Basile,et al.  Biomarkers in colorectal cancer: Current clinical utility and future perspectives , 2018, World journal of clinical cases.

[268]  Xiang-Nan Li,et al.  RNA sequencing reveals the expression profiles of circRNA and indicates that circDDX17 acts as a tumor suppressor in colorectal cancer , 2018, Journal of experimental & clinical cancer research : CR.

[269]  Y. Wang,et al.  CircMTO1 inhibits cell proliferation and invasion by regulating Wnt/β-catenin signaling pathway in colorectal cancer. , 2018, European review for medical and pharmacological sciences.

[270]  Jian-jun Peng,et al.  Long noncoding RNA B3GALT5-AS1 suppresses colon cancer liver metastasis via repressing microRNA-203 , 2018, Aging.

[271]  G. Cui,et al.  Contribution of IL-33 to the Pathogenesis of Colorectal Cancer , 2018, Front. Oncol..

[272]  P. Vineis,et al.  DNA methylation and associated gene expression in blood prior to lung cancer diagnosis in the Norwegian Women and Cancer cohort , 2018, Scientific Reports.

[273]  Yaming Wang,et al.  miR-125a-5p suppresses colorectal cancer progression by targeting VEGFA , 2018, Cancer management and research.

[274]  Chungang Liu,et al.  Circular RNA hsa_circ_0000523 regulates the proliferation and apoptosis of colorectal cancer cells as miRNA sponge , 2018, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

[275]  I. Tomlinson,et al.  Serum- and Glucocorticoid-induced Kinase Sgk1 Directly Promotes the Differentiation of Colorectal Cancer Cells and Restrains Metastasis , 2018, Clinical Cancer Research.

[276]  Qiong Liu,et al.  HLTF suppresses the migration and invasion of colorectal cancer cells via TGF‑β/SMAD signaling in vitro. , 2018, International journal of oncology.

[277]  Yi Sun,et al.  Hsa_circRNA_103809 regulated the cell proliferation and migration in colorectal cancer via miR-532-3p / FOXO4 axis. , 2018, Biochemical and biophysical research communications.

[278]  Xing-ming Jiang,et al.  The role of long non-coding RNA AFAP1-AS1 in human malignant tumors. , 2018, Pathology, research and practice.

[279]  Shuwei Zhang,et al.  Silencing of cytoskeleton-associated protein 2 represses cell proliferation and induces cell cycle arrest and cell apoptosis in osteosarcoma cells. , 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[280]  Yu-qin Pan,et al.  The long noncoding RNA SNHG1 regulates colorectal cancer cell growth through interactions with EZH2 and miR-154-5p , 2018, Molecular Cancer.

[281]  Lu Zhang,et al.  NEK4 kinase regulates EMT to promote lung cancer metastasis , 2018, Journal of cellular and molecular medicine.

[282]  Lei Zheng,et al.  The CircRNA-ACAP2/Hsa-miR-21-5p/ Tiam1 Regulatory Feedback Circuit Affects the Proliferation, Migration, and Invasion of Colon Cancer SW480 Cells , 2018, Cellular Physiology and Biochemistry.

[283]  M. Zheng,et al.  LncRNA SLCO4A1-AS1 facilitates growth and metastasis of colorectal cancer through β-catenin-dependent Wnt pathway , 2018, Journal of experimental & clinical cancer research : CR.

[284]  Jie Yang,et al.  Circ-ZNF609 promotes migration of colorectal cancer by inhibiting Gli1 expression via microRNA-150. , 2018, Journal of B.U.ON. : official journal of the Balkan Union of Oncology.

[285]  R. Aktimur,et al.  Clinical Value of CXCL5 for Determining of Colorectal Cancer , 2018, Asian Pacific journal of cancer prevention : APJCP.

[286]  Hao Jiang,et al.  Hsa_circ_0003998 promotes cell proliferation and invasion by targeting miR-326 in non-small cell lung cancer , 2018, OncoTargets and therapy.

[287]  L. Ding,et al.  The Dual Role of MicroRNAs in Colorectal Cancer Progression , 2018, International journal of molecular sciences.

[288]  C. Yeh,et al.  PTPRT and PTPRD Deleterious Mutations and Deletion Predict Bevacizumab Resistance in Metastatic Colorectal Cancer Patients , 2018, Cancers.

[289]  Bing Hu,et al.  CircRNA_100290 promotes colorectal cancer progression through miR-516b-induced downregulation of FZD4 expression and Wnt/β-catenin signaling. , 2018, Biochemical and biophysical research communications.

[290]  Yuan Yuan,et al.  CircRNA circ_0026344 as a prognostic biomarker suppresses colorectal cancer progression via microRNA-21 and microRNA-31. , 2018, Biochemical and biophysical research communications.

[291]  Jianming Zhang,et al.  Circular RNA circITGA7 inhibits colorectal cancer growth and metastasis by modulating the Ras pathway and upregulating transcription of its host gene ITGA7 , 2018, The Journal of pathology.

[292]  Jinyun Li,et al.  The expression profile and clinical application potential of hsa_circ_0000711 in colorectal cancer , 2018, Cancer management and research.

[293]  Bin Wu,et al.  Let‑7d inhibits colorectal cancer cell proliferation through the CST1/p65 pathway. , 2018, International journal of oncology.

[294]  Zhe-yu Chen,et al.  Long non‐coding RNA PlncRNA‐1 promotes cell proliferation and hepatic metastasis in colorectal cancer , 2018, Journal of cellular biochemistry.

[295]  S. Czinn,et al.  Upregulation of RASSF1A in Colon Cancer by Suppression of Angiogenesis Signaling and Akt Activation , 2018, Cellular Physiology and Biochemistry.

[296]  Jing Li,et al.  Differentially expressed lncRNAs and mRNAs identified by NGS analysis in colorectal cancer patients , 2018, Cancer medicine.

[297]  Andreu Alibés,et al.  Epigenetic and transcriptional dysregulation of VWA2 associated with a MYC-driven oncogenic program in colorectal cancer , 2018, Scientific Reports.

[298]  Jian Li,et al.  MicroRNA‐383 acts as a tumor suppressor in colorectal cancer by modulating CREPT/RPRD1B expression , 2018, Molecular carcinogenesis.

[299]  F. Fu,et al.  Up-regulated miR-29c inhibits cell proliferation and glycolysis by inhibiting SLC2A3 expression in prostate cancer. , 2018, Gene.

[300]  Tingting Li,et al.  Long non-coding RNA SNHG15 interacts with and stabilizes transcription factor Slug and promotes colon cancer progression. , 2018, Cancer letters.

[301]  H. Fan,et al.  Long non-coding RNA PVT1 as a novel potential biomarker for predicting the prognosis of colorectal cancer , 2018, The International journal of biological markers.

[302]  G. Reid,et al.  A data-driven, knowledge-based approach to biomarker discovery: application to circulating microRNA markers of colorectal cancer prognosis , 2018, npj Systems Biology and Applications.

[303]  G. Hu,et al.  LncRNA OIP5-AS1 regulates radioresistance by targeting DYRK1A through miR-369-3p in colorectal cancer cells. , 2018, European journal of cell biology.

[304]  Z. Dongsheng,et al.  Hsa_circ_0071589 promotes carcinogenesis via the miR-600/EZH2 axis in colorectal cancer. , 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[305]  Ning Zhang,et al.  Long noncoding RNA BC200 regulates cell growth and invasion in colon cancer. , 2018, The international journal of biochemistry & cell biology.

[306]  Haoran Hu,et al.  Circular RNA hsa_circ_0000567 can be used as a promising diagnostic biomarker for human colorectal cancer , 2018, Journal of clinical laboratory analysis.

[307]  X. Fang,et al.  Knockdown of CEMIP suppresses proliferation and induces apoptosis in colorectal cancer cells: downregulation of GRP78 and attenuation of unfolded protein response. , 2018, Biochemistry and cell biology = Biochimie et biologie cellulaire.

[308]  Zhi-yan Hu,et al.  FSTL1 interacts with VIM and promotes colorectal cancer metastasis via activating the focal adhesion signalling pathway , 2018, Cell Death & Disease.

[309]  Z. Tian,et al.  The lncRNA ZEB1-AS1 sponges miR-181a-5p to promote colorectal cancer cell proliferation by regulating Wnt/β-catenin signaling , 2018, Cell cycle.

[310]  Jiaxiang Wang,et al.  LncRNA TUG1 promoted KIAA1199 expression via miR-600 to accelerate cell metastasis and epithelial-mesenchymal transition in colorectal cancer , 2018, Journal of Experimental & Clinical Cancer Research.

[311]  Z. Qin,et al.  MiR-598 Suppresses Invasion and Migration by Negative Regulation of Derlin-1 and Epithelial-Mesenchymal Transition in Non-Small Cell Lung Cancer , 2018, Cellular Physiology and Biochemistry.

[312]  S. Pedersen,et al.  Methylation and Gene Expression of BCAT1 and IKZF1 in Colorectal Cancer Tissues , 2018, Clinical Medicine Insights. Oncology.

[313]  Xinhan Zhao,et al.  Long non-coding RNA HOXD-AS1 promotes tumor progression and predicts poor prognosis in colorectal cancer , 2018, International journal of oncology.

[314]  Huiming Sun,et al.  A Positive Feed-Forward Loop between LncRNA-CYTOR and Wnt/β-Catenin Signaling Promotes Metastasis of Colon Cancer. , 2018, Molecular therapy : the journal of the American Society of Gene Therapy.

[315]  Yong Wang,et al.  Long noncoding RNA DANCR promotes colorectal cancer proliferation and metastasis via miR-577 sponging , 2018, Experimental & Molecular Medicine.

[316]  Huan-Xi Li,et al.  Peroxiredoxin 1 promoted tumor metastasis and angiogenesis in colorectal cancer. , 2018, Pathology, research and practice.

[317]  Z. Tu,et al.  MicroRNA-383 suppresses cell proliferation and invasion in colorectal cancer by directly targeting paired box 6. , 2018, Molecular medicine reports.

[318]  D. Gibson,et al.  Age and Age-Related Diseases: Role of Inflammation Triggers and Cytokines , 2018, Front. Immunol..

[319]  R. Price,et al.  Differential role of CXCR3 in inflammation and colorectal cancer , 2018, Oncotarget.

[320]  B. Alipoor,et al.  THE ASSOCIATION OF PLASMA LEVELS OF miR-34a AND miR-149 WITH OBESITY AND INSULIN RESISTANCE IN OBESE CHILDREN AND ADOLESCENTS. , 2018, Acta endocrinologica.

[321]  N. Karin Chemokines and cancer: new immune checkpoints for cancer therapy. , 2018, Current opinion in immunology.

[322]  Yu-qin Pan,et al.  CircHIPK3 promotes colorectal cancer growth and metastasis by sponging miR-7 , 2018, Cell Death & Disease.

[323]  P. Liu,et al.  Methylation-Mediated Silencing of GATA5 Gene Suppresses Cholangiocarcinoma Cell Proliferation and Metastasis , 2018, Translational oncology.

[324]  Hsuan Liu,et al.  Linc00659, a long noncoding RNA, acts as novel oncogene in regulating cancer cell growth in colorectal cancer , 2018, Molecular Cancer.

[325]  Yu Cao,et al.  Chemokine CXCL3 mediates prostate cancer cells proliferation, migration and gene expression changes in an autocrine/paracrine fashion , 2018, International Urology and Nephrology.

[326]  Yue Zhang,et al.  Construction of a ceRNA network reveals potential lncRNA biomarkers in rectal adenocarcinoma , 2018, Oncology reports.

[327]  Su Jin Lee,et al.  c‐MET Overexpression in Colorectal Cancer: A Poor Prognostic Factor for Survival , 2018, Clinical colorectal cancer.

[328]  N. Zhou,et al.  Prognostic and clinicopathological value of p16 protein aberrant expression in colorectal cancer , 2018, Medicine.

[329]  Yong Zhu,et al.  miR‑1273g‑3p promotes proliferation, migration and invasion of LoVo cells via cannabinoid receptor 1 through activation of ERBB4/PIK3R3/mTOR/S6K2 signaling pathway. , 2018, Molecular medicine reports.

[330]  Xiaofei Yan,et al.  Suppression of Capn4 by microRNA-1271 impedes the proliferation and invasion of colorectal cancer cells. , 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[331]  Landian Hu,et al.  TRIP13 promotes tumor growth and is associated with poor prognosis in colorectal cancer , 2018, Cell Death & Disease.

[332]  Xueqing Li,et al.  miR-205-5p/PTK7 axis is involved in the proliferation, migration and invasion of colorectal cancer cells , 2018, Molecular medicine reports.

[333]  S. Anand,et al.  Age-related differences in gene expression in colorectal cancer (CRC). , 2018 .

[334]  Shaofeng Wu,et al.  Hsa_circ_0001649: A circular RNA and potential novel biomarker for colorectal cancer. , 2018, Biochemical and biophysical research communications.

[335]  Jian Shen,et al.  MicroRNA-744 inhibits cellular proliferation and invasion of colorectal cancer by directly targeting oncogene Notch1. , 2018, Oncology research.

[336]  X. Gu,et al.  MicroRNA-155 acts as a tumor suppressor in colorectal cancer by targeting CTHRC1 in vitro , 2018, Oncology letters.

[337]  L. Xia,et al.  MiR-186-5p upregulation inhibits proliferation, metastasis and epithelial-to-mesenchymal transition of colorectal cancer cell by targeting ZEB1. , 2018, Archives of biochemistry and biophysics.

[338]  Cheng Chen,et al.  New insights into the regulatory role of microRNA in tumor angiogenesis and clinical implications , 2018, Molecular Cancer.

[339]  Shuhong Hao,et al.  MicroRNA-374b reduces the proliferation and invasion of colon cancer cells by regulation of LRH-1/Wnt signaling. , 2018, Gene.

[340]  S. Kadener,et al.  circRNAs in Cancer. , 2018, Current opinion in genetics & development.

[341]  Jinming Yu,et al.  MiR‐216a‐3p inhibits colorectal cancer cell proliferation through direct targeting COX‐2 and ALOX5 , 2018, Journal of cellular biochemistry.

[342]  L. Shen,et al.  miR-34a increases the sensitivity of colorectal cancer cells to 5-fluorouracil in vitro and in vivo. , 2018, American journal of cancer research.

[343]  Jun Wang,et al.  Hsa_circ_0014717 is downregulated in colorectal cancer and inhibits tumor growth by promoting p16 expression. , 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[344]  Zhi-yuan Yu,et al.  LncRNA HIF1A-AS2 positively affects the progression and EMT formation of colorectal cancer through regulating miR-129-5p and DNMT3A. , 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[345]  Xuewei Li,et al.  MicroRNA-125a-5p Mediates 3T3-L1 Preadipocyte Proliferation and Differentiation , 2018, Molecules.

[346]  Xiaodong Li,et al.  UBE2C promotes rectal carcinoma via miR-381 , 2018, Cancer biology & therapy.

[347]  Rong-Bin Liu,et al.  Advance in plasma SEPT9 gene methylation assay for colorectal cancer early detection , 2018, World journal of gastrointestinal oncology.

[348]  W. Xia,et al.  MicroRNA-511 Inhibits Cellular Proliferation and Invasion in Colorectal Cancer by Directly Targeting Hepatoma-Derived Growth Factor , 2018, Oncology research.

[349]  Zhi Li,et al.  SNCA Is a Functionally Low-Expressed Gene in Lung Adenocarcinoma , 2018, Genes.

[350]  Yan Qin,et al.  mir-106a regulates cell proliferation and apoptosis of colon cancer cells through targeting the PTEN/PI3K/AKT signaling pathway. , 2017, Oncology letters.

[351]  Hyungjoo Kim,et al.  Epigenetic inactivation of RUNX3 in colorectal cancer , 2017, Annals of surgical treatment and research.

[352]  Arul M. Chinnaiyan,et al.  Cancer transcriptome profiling at the juncture of clinical translation , 2017, Nature Reviews Genetics.

[353]  Ying Lin,et al.  Elevated transgelin/TNS1 expression is a potential biomarker in human colorectal cancer , 2017, Oncotarget.

[354]  Yuze Chen,et al.  Role of serine/threonine kinase 33 methylation in colorectal cancer and its clinical significance , 2017, Oncology letters.

[355]  Yier Qiu,et al.  MiR-27b directly targets Rab3D to inhibit the malignant phenotype in colorectal cancer , 2017, Oncotarget.

[356]  X. Pu,et al.  miR-221 inhibits autophagy and targets TP53INP1 in colorectal cancer cells. , 2017, Experimental and therapeutic medicine.

[357]  N. Ellis,et al.  Colorectal Cancer Disparity in African Americans: Risk Factors and Carcinogenic Mechanisms. , 2017, The American journal of pathology.

[358]  L. Tang,et al.  miR-17-3P regulates the proliferation and survival of colon cancer cells by targeting Par4. , 2017, Molecular medicine reports.

[359]  Mingzhi Zhang,et al.  Long Noncoding RNA PlncRNA-1 Promotes Colorectal Cancer Cell Progression by Regulating the PI3K/Akt Signaling Pathway , 2017, Oncology research.

[360]  E. A. Fry,et al.  Aberrant expression of ETS1 and ETS2 proteins in cancer. , 2018, Cancer reports and reviews.

[361]  J. Xu,et al.  Long non-coding RNA-422 acts as a tumor suppressor in colorectal cancer. , 2018, Biochemical and biophysical research communications.

[362]  Jian Zhao,et al.  SRPX2 regulates colon cancer cell metabolism by miR-192/215 via PI3K-Akt. , 2018, American journal of translational research.

[363]  Xiaojun Zhou,et al.  LncRNA AB073614 induces epithelial- mesenchymal transition of colorectal cancer cells via regulating the JAK/STAT3 pathway. , 2018, Cancer biomarkers : section A of Disease markers.

[364]  X Wang,et al.  Silencing of hsa_circ_0007534 suppresses proliferation and induces apoptosis in colorectal cancer cells. , 2018, European review for medical and pharmacological sciences.

[365]  K. Braun,et al.  Colorectal Cancer Screening Compliance among Asian and Pacific Islander Americans , 2018, Journal of Immigrant and Minority Health.

[366]  Manel Esteller,et al.  Non-coding RNAs, epigenetics, and cancer: tying it all together , 2018, Cancer and Metastasis Reviews.

[367]  Takashi Yamamoto,et al.  PLEKHN1 promotes apoptosis by enhancing Bax-Bak hetro-oligomerization through interaction with Bid in human colon cancer , 2018, Cell Death Discovery.

[368]  I. Berindan‐Neagoe,et al.  The silent healer: miR-205-5p up-regulation inhibits epithelial to mesenchymal transition in colon cancer cells by indirectly up-regulating E-cadherin expression , 2018, Cell Death & Disease.

[369]  C. Boland,et al.  A RNA-Sequencing approach for the identification of novel long non-coding RNA biomarkers in colorectal cancer , 2018, Scientific Reports.

[370]  Qi Zhou,et al.  MicroRNA-494 promotes cancer progression and targets adenomatous polyposis coli in colorectal cancer , 2018, Molecular Cancer.

[371]  Y. Huang,et al.  SHP2 associates with nuclear localization of STAT3: significance in progression and prognosis of colorectal cancer , 2017, Scientific Reports.

[372]  G. Wang,et al.  Up-regulation of lncRNA SNHG1 indicates poor prognosis and promotes cell proliferation and metastasis of colorectal cancer by activation of the Wnt/β-catenin signaling pathway , 2017, Oncotarget.

[373]  Xin Zhang,et al.  Long noncoding RNA HNF1A-AS1 indicates a poor prognosis of colorectal cancer and promotes carcinogenesis via activation of the Wnt/β-catenin signaling pathway. , 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[374]  François Modave,et al.  Colorectal cancer stages transcriptome analysis , 2017, PloS one.

[375]  Wenbin Liu,et al.  ALX4, an epigenetically down regulated tumor suppressor, inhibits breast cancer progression by interfering Wnt/β-catenin pathway , 2017, Journal of experimental & clinical cancer research : CR.

[376]  Qiang Yuan,et al.  Role of VEGFA gene polymorphisms in colorectal cancer patients who treated with bevacizumab , 2017, Oncotarget.

[377]  Yongqin Li,et al.  Therapeutic inhibition of SGK1 suppresses colorectal cancer , 2017, Experimental & Molecular Medicine.

[378]  J. Herranz,et al.  Targeting the lipid metabolic axis ACSL/SCD in colorectal cancer progression by therapeutic miRNAs: miR-19b-1 role[S] , 2017, Journal of Lipid Research.

[379]  Zhixin Chen,et al.  The expression profile and clinical significance of circRNA0003906 in colorectal cancer , 2017, OncoTargets and therapy.

[380]  Fenghua Wang,et al.  Long non-coding RNA UICLM promotes colorectal cancer liver metastasis by acting as a ceRNA for microRNA-215 to regulate ZEB2 expression , 2017, Theranostics.

[381]  Z. Qian,et al.  Circular RNA hsa_circ_000984 promotes colon cancer growth and metastasis by sponging miR-106b , 2017, Oncotarget.

[382]  Zeyang Chen,et al.  Long non-coding RNA lncTCF7 activates the Wnt/β-catenin pathway to promote metastasis and invasion in colorectal cancer , 2017, Oncology letters.

[383]  J. Mariadason,et al.  Aberrant DNA Methylation in Colorectal Cancer: What Should We Target? , 2017, Trends in cancer.

[384]  M. Weiser,et al.  The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Treatment of Colon Cancer. , 2017, Diseases of the colon and rectum.

[385]  S. Duan,et al.  DNA methylation of CMTM3, SSTR2, and MDFI genes in colorectal cancer. , 2017, Gene.

[386]  K. Janssen,et al.  Interferon-inducible CXC-chemokines are crucial immune modulators and survival predictors in colorectal cancer , 2017, Oncotarget.

[387]  He Li,et al.  DNA hypermethylated status and gene expression of PAX1/SOX1 in patients with colorectal carcinoma , 2017, OncoTargets and therapy.

[388]  Arnoud Boot,et al.  Methylation associated transcriptional repression of ELOVL5 in novel colorectal cancer cell lines , 2017, PloS one.

[389]  S. Duan,et al.  The role of TFPI2 hypermethylation in the detection of gastric and colorectal cancer , 2017, Oncotarget.

[390]  Yongzhi Yang,et al.  Long non-coding RNAs in Colorectal Cancer: Progression and Future Directions , 2017, Journal of Cancer.

[391]  C. O’Flanagan,et al.  Obesity and Cancer Metabolism: A Perspective on Interacting Tumor–Intrinsic and Extrinsic Factors , 2017, Front. Oncol..

[392]  Deepak K. Singh,et al.  Long Noncoding RNA PURPL Suppresses Basal p53 Levels and Promotes Tumorigenicity in Colorectal Cancer. , 2017, Cell reports.

[393]  A. Kalmár,et al.  Colorectal adenoma and cancer detection based on altered methylation pattern of SFRP1, SFRP2, SDC2, and PRIMA1 in plasma samples , 2017, Epigenetics.

[394]  H. Jarjanazi,et al.  Potential of RASSF1A promoter methylation as biomarker for endometrial cancer: A systematic review and meta-analysis. , 2017, Gynecologic oncology.

[395]  Xiaojun Zhou,et al.  LncRNA AB073614 regulates proliferation and metastasis of colorectal cancer cells via the PI3K/AKT signaling pathway. , 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[396]  I. Shureiqi,et al.  ALOX15 as a suppressor of inflammation and cancer: Lost in the link. , 2017, Prostaglandins & other lipid mediators.

[397]  F. Wang,et al.  Hsa_circ_0020397 regulates colorectal cancer cell viability, apoptosis and invasion by promoting the expression of the miR‐138 targets TERT and PD‐L1 , 2017, Cell biology international.

[398]  Lai Xu,et al.  Transcriptome analysis of human colorectal cancer biopsies reveals extensive expression correlations among genes related to cell proliferation, lipid metabolism, immune response and collagen catabolism , 2017, Oncotarget.

[399]  Baosen Zhou,et al.  Association of PPP1R13L and CD3EAP polymorphisms with risk and survival of non-small cell lung cancer in Chinese non-smoking females , 2017, Oncotarget.

[400]  J. Shay,et al.  Multiple Roles of APC and its Therapeutic Implications in Colorectal Cancer , 2017, Journal of the National Cancer Institute.

[401]  Zhonghua Ma,et al.  Long noncoding RNA CRNDE promotes colorectal cancer cell proliferation via epigenetically silencing DUSP5/CDKN1A expression , 2017, Cell Death & Disease.

[402]  N. Vickers,et al.  Animal Communication: When I’m Calling You, Will You Answer Too? , 2017, Current Biology.

[403]  P. Liu,et al.  Targeting MET in cancer therapy , 2017, Chronic diseases and translational medicine.

[404]  M. Kalady,et al.  RBP4-STRA6 Pathway Drives Cancer Stem Cell Maintenance and Mediates High-Fat Diet-Induced Colon Carcinogenesis , 2017, Stem cell reports.

[405]  Hyungjoo Kim,et al.  Abstract 4455: Identification of novel oncogene, copine-7 (CPNE7), in colorectal cancer , 2017 .

[406]  Kun-Hua Wang,et al.  Relationship Between Human mutL Homolog 1 (hMLH1) Hypermethylation and Colorectal Cancer: A Meta-Analysis , 2017, Medical science monitor : international medical journal of experimental and clinical research.

[407]  Dan Zhou,et al.  PCDH18 is frequently inactivated by promoter methylation in colorectal cancer , 2017, Scientific Reports.

[408]  M. Hong,et al.  Effects of moderate alcohol consumption on gene expression related to colonic inflammation and antioxidant enzymes in rats. , 2017, Alcohol.

[409]  Weiping Zou,et al.  Chemokines in the cancer microenvironment and their relevance in cancer immunotherapy , 2017, Nature Reviews Immunology.

[410]  M. van Engeland,et al.  NDRG4, an early detection marker for colorectal cancer, is specifically expressed in enteric neurons , 2017, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[411]  Huanbai Xu,et al.  The LIM protein AJUBA promotes colorectal cancer cell survival through suppression of JAK1/STAT1/IFIT2 network , 2017, Oncogene.

[412]  J. Turnay,et al.  Colorectal Cancer: From the Genetic Model to Posttranscriptional Regulation by Noncoding RNAs , 2017, BioMed research international.

[413]  S. Lo Tensins , 2017, Current Biology.

[414]  P. Lan,et al.  MicroRNA-30a regulates cell proliferation and tumor growth of colorectal cancer by targeting CD73 , 2017, BMC Cancer.

[415]  Laising Yen,et al.  Noncoding Effects of Circular RNA CCDC66 Promote Colon Cancer Growth and Metastasis. , 2017, Cancer research.

[416]  U. Mansmann,et al.  Methylated free‐circulating HPP1 DNA is an early response marker in patients with metastatic colorectal cancer , 2017, International journal of cancer.

[417]  C. Doglioni,et al.  Duodenal Mucosa of Patients With Type 1 Diabetes Shows Distinctive Inflammatory Profile and Microbiota , 2017, The Journal of clinical endocrinology and metabolism.

[418]  Bingwei Jin,et al.  The clinical value and biological function of PTTG1 in colorectal cancer. , 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[419]  M. Ebert,et al.  Apelin: A putative novel predictive biomarker for bevacizumab response in colorectal cancer , 2017, Oncotarget.

[420]  J. Kros,et al.  CMTM3 (CKLF-Like Marvel Transmembrane Domain 3) Mediates Angiogenesis by Regulating Cell Surface Availability of VE-Cadherin in Endothelial Adherens Junctions , 2017, Arteriosclerosis, thrombosis, and vascular biology.

[421]  V. Wagh,et al.  STRIP2 Is Indispensable for the Onset of Embryonic Stem Cell Differentiation , 2017, Molecular therapy. Methods & clinical development.

[422]  Liangliang Yang,et al.  Silencing CDR1as inhibits colorectal cancer progression through regulating microRNA-7 , 2017, OncoTargets and therapy.

[423]  T. Han,et al.  LncRNA CHRF-induced miR-489 loss promotes metastasis of colorectal cancer via TWIST1/EMT signaling pathway , 2017, Oncotarget.

[424]  T. Mäkelä,et al.  AMPK negatively regulates tensin-dependent integrin activity , 2017, The Journal of cell biology.

[425]  V. Young,et al.  Role of interferon‐γ and inflammatory monocytes in driving colonic inflammation during acute Clostridium difficile infection in mice , 2017, Immunology.

[426]  H. Qin,et al.  T-cell leukemia/lymphoma-1A predicts the clinical outcome for patients with stage II/III colorectal cancer. , 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[427]  Yun Chen,et al.  Circular BANP, an upregulated circular RNA that modulates cell proliferation in colorectal cancer. , 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[428]  You-chuan Xiao,et al.  CXCL8 induces epithelial-mesenchymal transition in colon cancer cells via the PI3K/Akt/NF-κB signaling pathway. , 2017, Oncology reports.

[429]  He Li,et al.  Roles of long noncoding RNAs in colorectal cancer metastasis , 2017, Oncotarget.

[430]  Brian T Palmisano,et al.  High-Fat Feeding Does Not Disrupt Daily Rhythms in Female Mice because of Protection by Ovarian Hormones , 2017, Front. Endocrinol..

[431]  Jianbo Wu,et al.  Identification of differentially expressed circular RNAs in human colorectal cancer , 2017, Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.

[432]  Hong Li,et al.  Long Non-Coding RNA Reprogramming (ROR) Promotes Cell Proliferation in Colorectal Cancer via Affecting P53 , 2017, Medical science monitor : international medical journal of experimental and clinical research.

[433]  C. Xiao,et al.  Reciprocal control of lncRNA-BCAT1 and β-catenin pathway reveals lncRNA-BCAT1 long non-coding RNA acts as a tumor suppressor in colorectal cancer , 2017, Oncotarget.

[434]  G. Cui,et al.  Value of CNRIP1 promoter methylation in colorectal cancer screening and prognosis assessment and its influence on the activity of cancer cells , 2017, Archives of medical science : AMS.

[435]  Toshiyoshi Fujiwara,et al.  Circular RNA ciRS-7—A Promising Prognostic Biomarker and a Potential Therapeutic Target in Colorectal Cancer , 2017, Clinical Cancer Research.

[436]  S. Srinivasan,et al.  Neuropeptide Y (NPY) promotes inflammation-induced tumorigenesis by enhancing epithelial cell proliferation. , 2017, American journal of physiology. Gastrointestinal and liver physiology.

[437]  Tao Wang,et al.  Knockdown of the differentially expressed gene TNFRSF12A inhibits hepatocellular carcinoma cell proliferation and migration in vitro , 2017, Molecular medicine reports.

[438]  Liang Cheng,et al.  Discovery and validation of immune-associated long non-coding RNA biomarkers associated with clinically molecular subtype and prognosis in diffuse large B cell lymphoma , 2017, Molecular Cancer.

[439]  E. Trotta,et al.  Human NF-κB repressing factor acts as a stress-regulated switch for ribosomal RNA processing and nucleolar homeostasis surveillance , 2017, Proceedings of the National Academy of Sciences.

[440]  B. Baradaran,et al.  Chitosan nanoparticles as a dual drug/siRNA delivery system for treatment of colorectal cancer. , 2017, Immunology letters.

[441]  AACR Project GENIE: Powering Precision Medicine through an International Consortium. , 2017, Cancer discovery.

[442]  Jiani Guo,et al.  Comprehensive profile of differentially expressed circular RNAs reveals that hsa_circ_0000069 is upregulated and promotes cell proliferation, migration, and invasion in colorectal cancer , 2016, OncoTargets and therapy.

[443]  Shan Wang,et al.  A novel long non-coding RNA lnc-GNAT1-1 is low expressed in colorectal cancer and acts as a tumor suppressor through regulating RKIP-NF-κB-Snail circuit , 2016, Journal of experimental & clinical cancer research : CR.

[444]  C. Hudis,et al.  Obesity and Cancer Mechanisms: Tumor Microenvironment and Inflammation. , 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[445]  G. Taylor,et al.  PRIMA-1Met suppresses colorectal cancer independent of p53 by targeting MEK , 2016, Oncotarget.

[446]  N. Neamati,et al.  Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor , 2016, Nature Communications.

[447]  Jing-mei Liu,et al.  CXCL9: evidence and contradictions for its role in tumor progression , 2016, Cancer medicine.

[448]  David H. Murray,et al.  A cross‐sectional study comparing a blood test for methylated BCAT1 and IKZF1 tumor‐derived DNA with CEA for detection of recurrent colorectal cancer , 2016, Cancer medicine.

[449]  S. Eschrich,et al.  Knockdown of CSE1L Gene in Colorectal Cancer Reduces Tumorigenesis in Vitro. , 2016, The American journal of pathology.

[450]  H. Lee,et al.  Favorable prognosis in colorectal cancer patients with co-expression of c-MYC and ß-catenin , 2016, BMC Cancer.

[451]  Doo Sin Jo,et al.  Inhibition of never in mitosis A (NIMA)-related kinase-4 reduces survivin expression and sensitizes cancer cells to TRAIL-induced cell death , 2016, Oncotarget.

[452]  Zhenjun Wang,et al.  Long non-coding RNA AFAP1-AS1 facilitates tumor growth and promotes metastasis in colorectal cancer , 2016, Biological Research.

[453]  J. Fichna,et al.  Circadian rhythm abnormalities — Association with the course of inflammatory bowel disease , 2016, Pharmacological reports : PR.

[454]  J. Medema,et al.  DNA methylation based biomarkers in colorectal cancer: A systematic review. , 2016, Biochimica et biophysica acta.

[455]  M. Koch,et al.  Serum MMP7, MMP10 and MMP12 level as negative prognostic markers in colon cancer patients , 2016, BMC Cancer.

[456]  E. Lianidou,et al.  Methylation status of the APC and RASSF1A promoter in cell-free circulating DNA and its prognostic role in patients with colorectal cancer. , 2016, Oncology letters.

[457]  R. Salehi,et al.  DNA methylation analysis of secreted frizzled-related protein 2 gene for the early detection of colorectal cancer in fecal DNA , 2016, Nigerian medical journal : journal of the Nigeria Medical Association.

[458]  Xiao Han,et al.  HIC1 attenuates invasion and metastasis by inhibiting the IL-6/STAT3 signalling pathway in human pancreatic cancer. , 2016, Cancer letters.

[459]  Fan Zhang,et al.  Long non-coding RNA CASC11 interacts with hnRNP-K and activates the WNT/β-catenin pathway to promote growth and metastasis in colorectal cancer. , 2016, Cancer letters.

[460]  Daici Chen,et al.  Overexpression of long non-coding RNA-CTD903 inhibits colorectal cancer invasion and migration by repressing Wnt/β-catenin signaling and predicts favorable prognosis. , 2016, International journal of oncology.

[461]  R. Silver,et al.  Neuroendocrine underpinnings of sex differences in circadian timing systems , 2016, The Journal of Steroid Biochemistry and Molecular Biology.

[462]  Xiangjian Chen,et al.  The long noncoding RNA CASC2 functions as a competing endogenous RNA by sponging miR-18a in colorectal cancer , 2016, Scientific Reports.

[463]  Y. Bhutia,et al.  SLC transporters as a novel class of tumour suppressors: identity, function and molecular mechanisms. , 2016, The Biochemical journal.

[464]  Y. Liu,et al.  Increased TEAD4 expression and nuclear localization in colorectal cancer promote epithelial–mesenchymal transition and metastasis in a YAP-independent manner , 2016, Oncogene.

[465]  Marco Greco,et al.  Worldwide burden of colorectal cancer: a review , 2016, Updates in Surgery.

[466]  H. Xie,et al.  Emerging roles of circRNA_001569 targeting miR-145 in the proliferation and invasion of colorectal cancer , 2016, Oncotarget.

[467]  S. E. Barker,et al.  Enhanced Ccl2-Ccr2 signaling drives more severe choroidal neovascularization with aging , 2016, Neurobiology of Aging.

[468]  L. Borthwick The IL-1 cytokine family and its role in inflammation and fibrosis in the lung , 2016, Seminars in Immunopathology.

[469]  H. Zhang,et al.  Relationships between p14ARF Gene Methylation and Clinicopathological Features of Colorectal Cancer: A Meta-Analysis , 2016, PloS one.

[470]  C. Croce,et al.  MAPK15 upregulation promotes cell proliferation and prevents DNA damage in male germ cell tumors , 2016, Oncotarget.

[471]  L. Lanikova,et al.  HIC1 Expression Distinguishes Intestinal Carcinomas Sensitive to Chemotherapy12 , 2016, Translational oncology.

[472]  S. Rubin,et al.  Chronic inflammation and risk of colorectal and other obesity‐related cancers: The health, aging and body composition study , 2016, International journal of cancer.

[473]  T. Ismail,et al.  Glutamate dependent NMDA receptor 2D is a novel angiogenic tumour endothelial marker in colorectal cancer , 2016, Oncotarget.

[474]  M. Nagai Pleckstrin homology-like domain, family A, member 1 (PHLDA1) and cancer. , 2016, Biomedical reports.

[475]  A. Saftoiu,et al.  Assessment of Oxidative Stress Genes SOD2 and SOD3 Polymorphisms Role in Human Colorectal Cancer , 2016, Current health sciences journal.

[476]  Chunfang Gao,et al.  Identification and verification of PRDX1 as an inflammation marker for colorectal cancer progression. , 2016, American journal of translational research.

[477]  Tao Yin,et al.  Targeting of cancer-associated fibroblasts enhances the efficacy of cancer chemotherapy by regulating the tumor microenvironment , 2016, Molecular medicine reports.

[478]  Michael R. Green,et al.  Common BRAF(V600E)-directed pathway mediates widespread epigenetic silencing in colorectal cancer and melanoma , 2016, Proceedings of the National Academy of Sciences.

[479]  M. Vinciguerra,et al.  Deregulated expression of cryptochrome genes in human colorectal cancer , 2016, Molecular Cancer.

[480]  M. Karin,et al.  Obesity and Cancer: The Oil that Feeds the Flame. , 2016, Cell metabolism.

[481]  M. Nikbakht,et al.  Expression of P33ING1b Protein in Colorectal Cancer , 2015, Middle East journal of digestive diseases.

[482]  B. Tang,et al.  Long non-coding RNAs in colorectal cancer , 2015, Oncotarget.

[483]  Qingchuan Zhao,et al.  NDRG4 stratifies the prognostic value of body mass index in colorectal cancer , 2015, Oncotarget.

[484]  V. Nfonsam,et al.  Gene Expression Analysis of Sporadic Early-Onset Rectal Adenocarcinoma. , 2016, Gastrointestinal cancer : research & therapy.

[485]  Lei Liu,et al.  Hsa_circ_0001649: A circular RNA and potential novel biomarker for hepatocellular carcinoma. , 2016, Cancer biomarkers : section A of Disease markers.

[486]  E. Voronov,et al.  IL-1 in Colon Inflammation, Colon Carcinogenesis and Invasiveness of Colon Cancer , 2015, Cancer Microenvironment.

[487]  D. Chang,et al.  EYA4 Acts as a New Tumor Suppressor Gene in Colorectal Cancer , 2015, Molecular carcinogenesis.

[488]  Xuning Wang,et al.  Decreased expression of hsa_circ_001988 in colorectal cancer and its clinical significances. , 2015, International journal of clinical and experimental pathology.

[489]  Jimmy Lin,et al.  Transcriptomics in cancer diagnostics: developments in technology, clinical research and commercialization , 2015, Expert review of molecular diagnostics.

[490]  Eman Alshawaf,et al.  Changes in the Adipose Tissue Expression of CD86 Costimulatory Ligand and CD163 Scavenger Receptor in Obesity and Type-2 Diabetes: Implication for Metabolic Disease , 2015 .

[491]  Ye Xu,et al.  Nuclear-enriched abundant transcript 1 as a diagnostic and prognostic biomarker in colorectal cancer , 2015, Molecular Cancer.

[492]  M. Ragusa,et al.  Non-coding landscapes of colorectal cancer. , 2015, World journal of gastroenterology.

[493]  H. Mo,et al.  Effect of Prolonged Radiotherapy Treatment Time on Survival Outcomes after Intensity-Modulated Radiation Therapy in Nasopharyngeal Carcinoma , 2015, PloS one.

[494]  Jae-Il Park,et al.  Wnt2 complements Wnt/β-catenin signaling in colorectal cancer , 2015, Oncotarget.

[495]  P. G. Nayak,et al.  Curcumin half analog modulates interleukin-6 and tumor necrosis factor-alpha in inflammatory bowel disease , 2015, Pharmacognosy magazine.

[496]  W. Baer-Dubowska,et al.  Wnt pathway antagonists, SFRP1, SFRP2, SOX17, and PPP2R2B, are methylated in gliomas and SFRP1 methylation predicts shorter survival , 2015, Journal of Applied Genetics.

[497]  Yang Liu,et al.  Over-expression of lncRNA DANCR is associated with advanced tumor progression and poor prognosis in patients with colorectal cancer. , 2015, International journal of clinical and experimental pathology.

[498]  A. Hartmann,et al.  DAPK loss in colon cancer tumor buds: implications for migration capacity of disseminating tumor cells , 2015, Oncotarget.

[499]  M. Otsuka,et al.  Circulating RNAs as new biomarkers for detecting pancreatic cancer. , 2015, World journal of gastroenterology.

[500]  M. Gayyed,et al.  c-MET expression in colorectal adenomas and primary carcinomas with its corresponding metastases. , 2015, Journal of gastrointestinal oncology.

[501]  Huajie Cai,et al.  cir-ITCH Plays an Inhibitory Role in Colorectal Cancer by Regulating the Wnt/β-Catenin Pathway , 2015, PloS one.

[502]  S. Zhang,et al.  KIF2A overexpression and its association with clinicopathologic characteristics and unfavorable prognosis in colorectal cancer , 2015, Tumor Biology.

[503]  Jun Yu,et al.  Carbonic anhydrase IV inhibits colon cancer development by inhibiting the Wnt signalling pathway through targeting the WTAP–WT1–TBL1 axis , 2015, Gut.

[504]  Michal Mikula,et al.  Expression changes of cell-cell adhesion-related genes in colorectal tumors. , 2015, Oncology letters.

[505]  Huamin Wang,et al.  Long non-coding RNA CCAL regulates colorectal cancer progression by activating Wnt/β-catenin signalling pathway via suppression of activator protein 2α , 2015, Gut.

[506]  Q. Zhong,et al.  Twist1 is a potential prognostic marker for colorectal cancer and associated with chemoresistance. , 2015, American journal of cancer research.

[507]  David H. Murray,et al.  A Two-Gene Blood Test for Methylated DNA Sensitive for Colorectal Cancer , 2015, PloS one.

[508]  A. Papavassiliou,et al.  Expression and promoter methylation status of hMLH1, MGMT, APC, and CDH1 genes in patients with colon adenocarcinoma , 2015, Experimental biology and medicine.

[509]  G. Núñez,et al.  Distinct Commensals Induce Interleukin-1β via NLRP3 Inflammasome in Inflammatory Monocytes to Promote Intestinal Inflammation in Response to Injury. , 2015, Immunity.

[510]  Tesshi Yamada,et al.  α-Actinin-4 Enhances Colorectal Cancer Cell Invasion by Suppressing Focal Adhesion Maturation , 2015, PloS one.

[511]  J. Bohr,et al.  Enhanced Levels of Chemokines and Their Receptors in the Colon of Microscopic Colitis Patients Indicate Mixed Immune Cell Recruitment , 2015, Mediators of inflammation.

[512]  J. O. Lee,et al.  The effect of high glucose levels on the hypermethylation of protein phosphatase 1 regulatory subunit 3C (PPP1R3C) gene in colorectal cancer , 2015, Journal of Genetics.

[513]  Zhi-gang Huang,et al.  Combined detection of plasma GATA5 and SFRP2 methylation is a valid noninvasive biomarker for colorectal cancer and adenomas. , 2015, World journal of gastroenterology.

[514]  Qi Guo,et al.  Detection of SNCA and FBN1 Methylation in the Stool as a Biomarker for Colorectal Cancer , 2015, Disease markers.

[515]  C. Curtis,et al.  A Big Bang model of human colorectal tumor growth , 2015, Nature Genetics.

[516]  R. Zeillinger,et al.  Correlation of circular RNA abundance with proliferation – exemplified with colorectal and ovarian cancer, idiopathic lung fibrosis, and normal human tissues , 2015, Scientific Reports.

[517]  Weiwei Dong,et al.  Quantitative detection of methylated NDRG4 gene as a candidate biomarker for diagnosis of colorectal cancer , 2014, Oncology letters.

[518]  A. Goel,et al.  Active secretion of CXCL10 and CCL5 from colorectal cancer microenvironments associates with GranzymeB+ CD8+ T-cell infiltration , 2014, Oncotarget.

[519]  Jaw-Yuan Wang,et al.  LINE-1 Methylation Status Correlates Significantly to Post-Therapeutic Recurrence in Stage III Colon Cancer Patients Receiving FOLFOX-4 Adjuvant Chemotherapy , 2015, PloS one.

[520]  Wenhui Liu,et al.  Insulin-Like Growth Factor-1 Modulates Polycomb Cbx8 Expression and Inhibits Colon Cancer Cell Apoptosis , 2015, Cell Biochemistry and Biophysics.

[521]  Nita Ahuja,et al.  Spectrin Repeat Containing Nuclear Envelope 1 and Forkhead Box Protein E1 Are Promising Markers for the Detection of Colorectal Cancer in Blood , 2014, Cancer Prevention Research.

[522]  F. D. De Braud,et al.  Role of MGMT as biomarker in colorectal cancer. , 2014, World journal of clinical cases.

[523]  R. Soong,et al.  Postoperative serum methylation levels of TAC1 and SEPT9 are independent predictors of recurrence and survival of patients with colorectal cancer , 2014, Cancer.

[524]  Midie Xu,et al.  Long non-coding RNAs in colorectal cancer: implications for pathogenesis and clinical application , 2014, Modern Pathology.

[525]  Y. Sang,et al.  Paradoxical role of CBX8 in proliferation and metastasis of colorectal cancer , 2014, Oncotarget.

[526]  Jinneng Cao The functional role of long non-coding RNAs and epigenetics , 2014, Biological Procedures Online.

[527]  Z. Hong,et al.  PER3, a novel target of miR-103, plays a suppressive role in colorectal cancer in vitro , 2014, BMB reports.

[528]  A. Scorilas,et al.  KLK11 mRNA expression predicts poor disease-free and overall survival in colorectal adenocarcinoma patients. , 2014, Biomarkers in medicine.

[529]  R. Alizadeh-Navaei,et al.  Promoter methylation analysis of WNT/β-catenin pathway regulators and its association with expression of DNMT1 enzyme in colorectal cancer , 2014, Journal of Biomedical Science.

[530]  Shiliang Huang,et al.  DNA methylation analysis of SFRP2, GATA4/5, NDRG4 and VIM for the detection of colorectal cancer in fecal DNA , 2014, Oncology letters.

[531]  Xu Wang,et al.  Silencing NPAS2 promotes cell growth and invasion in DLD-1 cells and correlated with poor prognosis of colorectal cancer. , 2014, Biochemical and biophysical research communications.

[532]  Yu-Fang Song,et al.  The E3 Ligase RNF34 is a Novel Negative Regulator of the NOD1 Pathway , 2014, Cellular Physiology and Biochemistry.

[533]  Jian Qi,et al.  Detection of promoter hypermethylation of Wnt antagonist genes in fecal samples for diagnosis of early colorectal cancer. , 2014, World journal of gastroenterology.

[534]  J. O. Lee,et al.  Alcohol induces cell proliferation via hypermethylation of ADHFE1 in colorectal cancer cells , 2014, BMC Cancer.

[535]  J. Ivaska,et al.  Tensin-4-Dependent MET Stabilization Is Essential for Survival and Proliferation in Carcinoma Cells , 2014, Developmental cell.

[536]  H. Aburatani,et al.  Aberrant promoter methylation of PPP1R3C and EFHD1 in plasma of colorectal cancer patients , 2014, Cancer medicine.

[537]  M. Zang,et al.  Induction of the CLOCK Gene by E2-ERα Signaling Promotes the Proliferation of Breast Cancer Cells , 2014, PloS one.

[538]  Batoul Y. Abdallah,et al.  Unstable genomes elevate transcriptome dynamics , 2014, International journal of cancer.

[539]  M. Pillaire,et al.  Expression of the Microtubule-Associated Protein MAP9/ASAP and Its Partners AURKA and PLK1 in Colorectal and Breast Cancers , 2014, Disease markers.

[540]  Y. Matsumura,et al.  Role of SLC6A6 in promoting the survival and multidrug resistance of colorectal cancer , 2014, Scientific Reports.

[541]  Chuanhui Xu,et al.  Prognostic Significance of Cyclin D1 Expression in Colorectal Cancer: A Meta-Analysis of Observational Studies , 2014, PloS one.

[542]  A. Luster,et al.  Chemokines and chemokine receptors: positioning cells for host defense and immunity. , 2014, Annual review of immunology.

[543]  T. Masaki,et al.  Expression profiles of 507 proteins from a biotin label-based antibody array in human colorectal cancer. , 2014, Oncology reports.

[544]  M. Gazouli,et al.  Clock genes: their role in colorectal cancer. , 2014, World journal of gastroenterology.

[545]  Li-Sheng Chen,et al.  p33ING1b methylation in fecal DNA as a molecular screening tool for colorectal cancer and precancerous lesions , 2014, Oncology letters.

[546]  D. Flaherty,et al.  Obesity induced by a high-fat diet is associated with increased immune cell entry into the central nervous system , 2014, Brain, Behavior, and Immunity.

[547]  J. Khan,et al.  The Significance of Transcriptome Sequencing in Personalized Cancer Medicine , 2014 .

[548]  A. Cox,et al.  Identification of Candidate Driver Genes in Common Focal Chromosomal Aberrations of Microsatellite Stable Colorectal Cancer , 2013, PloS one.

[549]  K. Mimori,et al.  Significance of INHBA expression in human colorectal cancer. , 2013, Oncology reports.

[550]  F. Brunetti,et al.  Aberrant methylation of NPY, PENK, and WIF1 as a promising marker for blood-based diagnosis of colorectal cancer , 2013, BMC Cancer.

[551]  T. Martin,et al.  Biological influence of brain-derived neurotrophic factor (BDNF) on colon cancer cells , 2013, Experimental and therapeutic medicine.

[552]  A. Scorilas,et al.  Clinical significance of kallikrein-related peptidase (KLK10) mRNA expression in colorectal cancer. , 2013, Clinical biochemistry.

[553]  R. Biondi,et al.  Differential Stability of Cell-Free Circulating microRNAs: Implications for Their Utilization as Biomarkers , 2013, PloS one.

[554]  J. Clements,et al.  Metastasis of ovarian cancer is mediated by kallikrein related peptidases , 2013, Clinical & Experimental Metastasis.

[555]  X. Puente,et al.  Identification of novel tumor suppressor proteases by degradome profiling of colorectal carcinomas , 2013, Oncotarget.

[556]  L. Vreede,et al.  Germline mutations in the spindle assembly checkpoint genes BUB1 and BUB3 are risk factors for colorectal cancer. , 2013, Gastroenterology.

[557]  M. Delorenzi,et al.  DUSP 4 expression identifies a subset of colorectal cancer tumors that differ in MAPK activation, regardless of the genotype , 2013, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.

[558]  Xia Li,et al.  Correlation of MLH1 and MGMT methylation levels between peripheral blood leukocytes and colorectal tissue DNA samples in colorectal cancer patients , 2013, Oncology letters.

[559]  Qi Guo,et al.  Detection of hypermethylated fibrillin-1 in the stool samples of colorectal cancer patients , 2013, Medical Oncology.

[560]  F. Bazzoli,et al.  Molecular Pathways Involved in Colorectal Cancer: Implications for Disease Behavior and Prevention , 2013, International journal of molecular sciences.

[561]  C. Tang,et al.  Serum methylation levels of TAC1. SEPT9 and EYA4 as diagnostic markers for early colorectal cancers: a pilot study , 2013, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.

[562]  H. Chung,et al.  Genome-wide identification and validation of a novel methylation biomarker, SDC2, for blood-based detection of colorectal cancer. , 2013, The Journal of molecular diagnostics : JMD.

[563]  Gabriel Capellá,et al.  DNA Methylation Biomarkers for Noninvasive Diagnosis of Colorectal Cancer , 2013, Cancer Prevention Research.

[564]  C. Rao,et al.  Genomic Instability and Colon Carcinogenesis: From the Perspective of Genes , 2013, Front. Oncol..

[565]  Shuang Wu,et al.  IRF4 promotes cell proliferation by JNK pathway in multiple myeloma , 2013, Medical Oncology.

[566]  Wenlin Huang,et al.  Cryptochrome 1 Overexpression Correlates with Tumor Progression and Poor Prognosis in Patients with Colorectal Cancer , 2013, PloS one.

[567]  Batoul Y. Abdallah,et al.  Chromosomal instability and transcriptome dynamics in cancer , 2013, Cancer and Metastasis Reviews.

[568]  Jinghong Xu,et al.  miRNA-27b Targets Vascular Endothelial Growth Factor C to Inhibit Tumor Progression and Angiogenesis in Colorectal Cancer , 2013, PloS one.

[569]  P. Azimzadeh,et al.  Association of co-stimulatory human B-lymphocyte antigen B7-2 (CD86) gene polymorphism with colorectal cancer risk , 2013, Gastroenterology and hepatology from bed to bench.

[570]  Tomomi Tanaka,et al.  Transcriptional Regulation of Fucosyltransferase 1 Gene Expression in Colon Cancer Cells , 2013, TheScientificWorldJournal.

[571]  J. Kjems,et al.  Natural RNA circles function as efficient microRNA sponges , 2013, Nature.

[572]  J. Olefsky,et al.  The Origins and Drivers of Insulin Resistance , 2013, Cell.

[573]  Caitlyn W. Barrett,et al.  Tumor suppressor function of the plasma glutathione peroxidase gpx3 in colitis-associated carcinoma. , 2013, Cancer research.

[574]  H. Zhang,et al.  Detection of Hypermethylated Spastic Paraplegia-20 in Stool Samples of Patients with Colorectal Cancer , 2013, International journal of medical sciences.

[575]  Manuela Gariboldi,et al.  Effects of Warm Ischemic Time on Gene Expression Profiling in Colorectal Cancer Tissues and Normal Mucosa , 2013, PloS one.

[576]  Jianping Wang,et al.  RET is a potential tumor suppressor gene in colorectal cancer , 2012, Oncogene.

[577]  M. Roselli,et al.  von Hippel Lindau disease with colon adenocarcinoma, renal cell carcinoma and adrenal pheochromocytoma. , 2013, Internal medicine.

[578]  Dong Kyung Chang,et al.  Alcohol dehydrogenase, iron containing, 1 promoter hypermethylation associated with colorectal cancer differentiation , 2013, BMC Cancer.

[579]  R. Salehi,et al.  Methylation pattern of SFRP1 promoter in stool sample is a potential marker for early detection of colorectal cancer , 2012, Advanced biomedical research.

[580]  P. Laird,et al.  Genome-Scale Discovery of DNA-Methylation Biomarkers for Blood-Based Detection of Colorectal Cancer , 2012, PloS one.

[581]  Jishu Shi,et al.  IL-1β promotes stemness and invasiveness of colon cancer cells through Zeb1 activation , 2012, Molecular Cancer.

[582]  O. Froy Circadian Rhythms and Obesity in Mammals , 2012, ISRN obesity.

[583]  M. Neurath,et al.  Interleukin-6 - A Key Regulator of Colorectal Cancer Development , 2012, International journal of biological sciences.

[584]  Yun Hee Kang,et al.  ESM-1 regulates cell growth and metastatic process through activation of NF-κB in colorectal cancer. , 2012, Cellular signalling.

[585]  P. Townsend,et al.  The retinoblastoma protein (Rb) as an anti-apoptotic factor: expression of Rb is required for the anti-apoptotic function of BAG-1 protein in colorectal tumour cells , 2012, Cell Death and Disease.

[586]  M. Zali,et al.  Relationship between Insulin Receptor (INSR rs 1799817) and Colorectal Cancer (CRC) , 2012 .

[587]  S. Lipkin,et al.  Chemokine 25-induced signaling suppresses colon cancer invasion and metastasis. , 2012, The Journal of clinical investigation.

[588]  J. Löhr,et al.  Alcohol consumption and digestive tract cancer , 2012, Current opinion in clinical nutrition and metabolic care.

[589]  Qilong Yi,et al.  DNA methylation patterns in blood of patients with colorectal cancer and adenomatous colorectal polyps , 2012, International journal of cancer.

[590]  S. Ohnuma,et al.  IL-23 directly enhances the proliferative and invasive activities of colorectal carcinoma. , 2012, Oncology letters.

[591]  W. Hahn,et al.  Nek4 Regulates Entry into Replicative Senescence and the Response to DNA Damage in Human Fibroblasts , 2012, Molecular and Cellular Biology.

[592]  Fen Nie,et al.  The E3 Ubiquitin Ligase ITCH Negatively Regulates Canonical Wnt Signaling by Targeting Dishevelled Protein , 2012, Molecular and Cellular Biology.

[593]  G. Meijer,et al.  Analytical sensitivity and stability of DNA methylation testing in stool samples for colorectal cancer detection , 2012, Cellular Oncology.

[594]  Crispin J. Miller,et al.  Enhanced stability of microRNA expression facilitates classification of FFPE tumour samples exhibiting near total mRNA degradation , 2012, British Journal of Cancer.

[595]  J. Tabernero,et al.  Molecular Profiling of Patients with Colorectal Cancer and Matched Targeted Therapy in Phase I Clinical Trials , 2012, Molecular Cancer Therapeutics.

[596]  S. Kaneko,et al.  CCR5 Plays a Critical Role in Obesity-Induced Adipose Tissue Inflammation and Insulin Resistance by Regulating Both Macrophage Recruitment and M1/M2 Status , 2012, Diabetes.

[597]  O. Froy,et al.  Timed high‐fat diet resets circadian metabolism and prevents obesity , 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[598]  A. Schetter,et al.  The Role of MicroRNAs in Colorectal Cancer , 2012, Cancer journal.

[599]  R. Malekzadeh,et al.  The Insulin Receptor Substrate 1 (Irs1) in Intestinal Epithelial Differentiation and in Colorectal Cancer , 2012, PloS one.

[600]  G. Shulman,et al.  Mechanisms for Insulin Resistance: Common Threads and Missing Links , 2012, Cell.

[601]  Yuanyuan Xie,et al.  Detection of methylated tissue factor pathway inhibitor 2 and human long DNA in fecal samples of patients with colorectal cancer in China. , 2012, Cancer epidemiology.

[602]  H. Allawi,et al.  Quantification of methylated markers with a multiplex methylation-specific technology. , 2012, Clinical chemistry.

[603]  J. Mathers,et al.  Quantitative profiling of CpG island methylation in human stool for colorectal cancer detection , 2012, International Journal of Colorectal Disease.

[604]  N. Yusoff,et al.  Pilot study of the sensitivity and specificity of the DNA integrity assay for stool-based detection of colorectal cancer in Malaysian patients. , 2012, Asian Pacific journal of cancer prevention : APJCP.

[605]  K. D. Sørensen,et al.  Identification and validation of highly frequent CpG island hypermethylation in colorectal adenomas and carcinomas , 2011, International journal of cancer.

[606]  Zongyou Chen,et al.  Expression of circadian clock gene human Period2 (hPer2) in human colorectal carcinoma , 2011, World journal of surgical oncology.

[607]  G. Meijer,et al.  DNA Methylation of Phosphatase and Actin Regulator 3 Detects Colorectal Cancer in Stool and Complements FIT , 2011, Cancer Prevention Research.

[608]  C. Rotimi,et al.  The roles of IL-6, IL-10, and IL-1RA in obesity and insulin resistance in African-Americans. , 2011, The Journal of clinical endocrinology and metabolism.

[609]  R. Lothe,et al.  Identification of an epigenetic biomarker panel with high sensitivity and specificity for colorectal cancer and adenomas , 2011, Molecular Cancer.

[610]  Alfonso Valencia,et al.  Long-Range Epigenetic Silencing Associates with Deregulation of Ikaros Targets in Colorectal Cancer Cells , 2011, Molecular Cancer Research.

[611]  Alexander Crispin,et al.  Methylation of NEUROG1 in Serum Is a Sensitive Marker for the Detection of Early Colorectal Cancer , 2011, The American Journal of Gastroenterology.

[612]  D. Edwards,et al.  Matrix metalloproteinases: protective roles in cancer , 2011, Journal of cellular and molecular medicine.

[613]  N. Warner,et al.  The Nod2 sensor promotes intestinal pathogen eradication via the chemokine CCL2-dependent recruitment of inflammatory monocytes. , 2011, Immunity.

[614]  Wei Li,et al.  Recurrent chimeric RNAs enriched in human prostate cancer identified by deep sequencing , 2011, Proceedings of the National Academy of Sciences.

[615]  R. Lothe,et al.  SPG20, a novel biomarker for early detection of colorectal cancer, encodes a regulator of cytokinesis , 2011, Oncogene.

[616]  Martha L. Slattery,et al.  CpG Island Methylation in Colorectal Cancer: Past, Present and Future , 2011, Pathology research international.

[617]  M. Salaspuro Acetaldehyde and gastric cancer , 2011, Journal of digestive diseases.

[618]  Jun Liu,et al.  Diagnostic and prognostic value of the methylation status of secreted frizzled-related protein 2 in colorectal cancer. , 2011, Clinical and investigative medicine. Medecine clinique et experimentale.

[619]  Jun Yu,et al.  MicroRNA in colorectal cancer: from benchtop to bedside. , 2011, Carcinogenesis.

[620]  K. Kumamoto,et al.  Up-regulated Annexin A1 expression in gastrointestinal cancer is associated with cancer invasion and lymph node metastasis. , 2011, Experimental and therapeutic medicine.

[621]  H. Kim,et al.  Epigenomic Analysis of Aberrantly Methylated Genes in Colorectal Cancer Identifies Genes Commonly Affected by Epigenetic Alterations , 2011, Annals of Surgical Oncology.

[622]  Aihua Li,et al.  Small molecule antagonists for CXCR2 and CXCR1 inhibit human colon cancer liver metastases. , 2011, Cancer letters.

[623]  George A. Calin,et al.  RNA interference in the clinic: challenges and future directions , 2011, Nature Reviews Cancer.

[624]  Hua-yun Chen,et al.  Development of a multiplex MethyLight assay for the detection of multigene methylation in human colorectal cancer. , 2010, Cancer genetics and cytogenetics.

[625]  Takahiro Tanaka,et al.  Biomarkers for Colorectal Cancer , 2010, International journal of molecular sciences.

[626]  Y. Cho,et al.  Detection of colorectal neoplasm using promoter methylation of ITGA4, SFRP2, and p16 in stool samples: a preliminary report in Korean patients. , 2010, Hepato-gastroenterology.

[627]  M. Esteller,et al.  Novel methylation panel for the early detection of colorectal tumors in stool DNA. , 2010, Clinical colorectal cancer.

[628]  R. Dahiya,et al.  356 SECRETED FRIZZLED-RELATED PROTEIN-5 (SFRP-5) IS EPIGENETICALLY DOWNREGULATED AND FUNCTIONS AS A TUMOR SUPPRESSOR IN RENAL CELL CANCER , 2010 .

[629]  Kenji Hibi,et al.  Methylation of TFPI2 gene is frequently detected in advanced well-differentiated colorectal cancer. , 2010, Anticancer research.

[630]  D. Compton,et al.  Mechanisms of Chromosomal Instability , 2010, Current Biology.

[631]  A. Boulesteix,et al.  Differential expression of the chemokines GRO-2, GRO-3, and interleukin-8 in colon cancer and their impact on metastatic disease and survival , 2010, International Journal of Colorectal Disease.

[632]  Duane A. Compton,et al.  Proliferation of aneuploid human cells is limited by a p53-dependent mechanism , 2010, The Journal of cell biology.

[633]  B. Balluff,et al.  Performance of Epigenetic Markers SEPT9 and ALX4 in Plasma for Detection of Colorectal Precancerous Lesions , 2010, PloS one.

[634]  Xin Zhang,et al.  [Expression and significance of CK7 and CK19 in colon cancer]. , 2010, Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology.

[635]  S. Baek,et al.  A potential proliferative gene, NUDT6, is down-regulated by green tea catechins at the posttranscriptional level. , 2010, The Journal of nutritional biochemistry.

[636]  Mitsugu Sekimoto,et al.  ATP11A is a novel predictive marker for metachronous metastasis of colorectal cancer. , 2009, Oncology reports.

[637]  S. Osada,et al.  Effect of hepatocyte growth factor on progression of liver metastasis in colorectal cancer. , 2010, Hepato-gastroenterology.

[638]  A. Keshavarzian,et al.  Alcohol stimulates activation of Snail, epidermal growth factor receptor signaling, and biomarkers of epithelial-mesenchymal transition in colon and breast cancer cells. , 2010, Alcoholism, clinical and experimental research.

[639]  Ye Xu,et al.  CXCL10 expression and prognostic significance in stage II and III colorectal cancer , 2010, Molecular Biology Reports.

[640]  D. Compton,et al.  Deviant Kinetochore Microtubule Dynamics Underlie Chromosomal Instability , 2009, Current Biology.

[641]  C. Besch-Williford,et al.  PRIMA-1 inhibits growth of breast cancer cells by re-activating mutant p53 protein. , 2009, International journal of oncology.

[642]  Chi-Jung Huang,et al.  Clinical meaning of age-related expression of fecal cytokeratin 19 in colorectal malignancy , 2009, BMC Cancer.

[643]  Joobae Park,et al.  Aberrant Methylation of APC, MGMT, RASSF2A, and Wif-1 Genes in Plasma as a Biomarker for Early Detection of Colorectal Cancer , 2009, Clinical Cancer Research.

[644]  A. Hyman,et al.  Motor-Independent Targeting of CLASPs to Kinetochores by CENP-E Promotes Microtubule Turnover and Poleward Flux , 2009, Current Biology.

[645]  N. Matsubara,et al.  Analysis of fecal DNA methylation to detect gastrointestinal neoplasia. , 2009, Journal of the National Cancer Institute.

[646]  Edward L. Lee,et al.  Distinct High-Profile Methylated Genes in Colorectal Cancer , 2009, PloS one.

[647]  S. Goodman,et al.  Sensitive digital quantification of DNA methylation in clinical samples , 2009, Nature Biotechnology.

[648]  G. Meijer,et al.  Promoter DNA Methylation of Oncostatin M receptor-β as a Novel Diagnostic and Therapeutic Marker in Colon Cancer , 2009, PloS one.

[649]  D. Park,et al.  Stool Methylation-Specific Polymerase Chain Reaction Assay for the Detection of Colorectal Neoplasia in Korean Patients , 2009, Diseases of the colon and rectum.

[650]  H. Moch,et al.  VHL loss causes spindle misorientation and chromosome instability , 2009, Nature Cell Biology.

[651]  M. Washington,et al.  Comparative analysis of PCR-based biomarker assay methods for colorectal polyp detection from fecal DNA. , 2009, Clinical chemistry.

[652]  J. Herman,et al.  N-Myc downstream-regulated gene 4 (NDRG4): a candidate tumor suppressor gene and potential biomarker for colorectal cancer. , 2009, Journal of the National Cancer Institute.

[653]  J. Herman,et al.  GATA4 and GATA5 are Potential Tumor Suppressors and Biomarkers in Colorectal Cancer , 2009, Clinical Cancer Research.

[654]  Pumin Zhang,et al.  Loss of spindle assembly checkpoint–mediated inhibition of Cdc20 promotes tumorigenesis in mice , 2009, The Journal of cell biology.

[655]  J. Herman,et al.  Methylation of TFPI2 in stool DNA: a potential novel biomarker for the detection of colorectal cancer. , 2009, Cancer research.

[656]  H. Heng,et al.  Genome based cell population heterogeneity promotes tumorigenicity: The evolutionary mechanism of cancer , 2009, Journal of cellular physiology.

[657]  H. Saya,et al.  K858, a novel inhibitor of mitotic kinesin Eg5 and antitumor agent, induces cell death in cancer cells. , 2009, Cancer research.

[658]  C. Prives,et al.  Blinded by the Light: The Growing Complexity of p53 , 2009, Cell.

[659]  V. Moreno,et al.  Long-range epigenetic silencing at 2q14.2 affects most human colorectal cancers and may have application as a non-invasive biomarker of disease , 2009, British Journal of Cancer.

[660]  C. Shu,et al.  Loss of p53 and MCT-1 Overexpression Synergistically Promote Chromosome Instability and Tumorigenicity , 2009, Molecular Cancer Research.

[661]  C. Dinarello,et al.  Immunological and inflammatory functions of the interleukin-1 family. , 2009, Annual review of immunology.

[662]  J. V. van Deursen,et al.  CAML loss causes anaphase failure and chromosome missegregation , 2009, Cell cycle.

[663]  V. Yang,et al.  Mouse embryonic fibroblasts null for the Krüppel-like factor 4 gene are genetically unstable , 2009, Oncogene.

[664]  D. Pellman,et al.  A little CIN may cost a lot: revisiting aneuploidy and cancer. , 2009, Current opinion in genetics & development.

[665]  Daniel G. Anderson,et al.  Knocking down barriers: advances in siRNA delivery , 2009, Nature Reviews Drug Discovery.

[666]  Joobae Park,et al.  TMAP/CKAP2 is essential for proper chromosome segregation , 2009, Cell Cycle.

[667]  C. Burge,et al.  Most mammalian mRNAs are conserved targets of microRNAs. , 2008, Genome research.

[668]  Samuel F. Bakhoum,et al.  Genome stability is ensured by temporal control of kinetochore-microtubule dynamics , 2008, Nature Cell Biology.

[669]  E. Dı́az-Rodrı́guez,et al.  Hec1 overexpression hyperactivates the mitotic checkpoint and induces tumor formation in vivo , 2008, Proceedings of the National Academy of Sciences.

[670]  P. Avan,et al.  Stereocilin-deficient mice reveal the origin of cochlear waveform distortions , 2008, Nature.

[671]  G. Sluder,et al.  MdmX regulates transformation and chromosomal stability in p53-deficient cells , 2008, Cell cycle.

[672]  F. Kittrell,et al.  Overexpression of Separase induces aneuploidy and mammary tumorigenesis , 2008, Proceedings of the National Academy of Sciences.

[673]  Y. Ba,et al.  The Circadian Gene NPAS2, a Putative Tumor Suppressor, Is Involved in DNA Damage Response , 2008, Molecular Cancer Research.

[674]  Y. Wong,et al.  Id-1 promotes chromosomal instability through modification of APC/C activity during mitosis in response to microtubule disruption , 2008, Oncogene.

[675]  H. Sugimura,et al.  Human Sgo1 downregulation leads to chromosomal instability in colorectal cancer , 2008, Gut.

[676]  B. Dieckgraefe,et al.  REG1A expression is a prognostic marker in colorectal cancer and associated with peritoneal carcinomatosis , 2008, International journal of cancer.

[677]  F. Barany,et al.  c-Met gene amplification is associated with advanced stage colorectal cancer and liver metastases. , 2008, Cancer letters.

[678]  K. Jiang,et al.  The mitotic checkpoint kinase NEK2A regulates kinetochore microtubule attachment stability , 2008, Oncogene.

[679]  Guojun Wu,et al.  Aberrant promoter methylation and tumor suppressive activity of the DFNA5 gene in colorectal carcinoma , 2008, Oncogene.

[680]  Yumay Chen,et al.  Hice1, a Novel Microtubule-Associated Protein Required for Maintenance of Spindle Integrity and Chromosomal Stability in Human Cells , 2008, Molecular and Cellular Biology.

[681]  Timothy Cardozo,et al.  Control of chromosome stability by the β-TrCP–REST–Mad2 axis , 2008, Nature.

[682]  T. Greiner,et al.  Elevated Mdm2 expression induces chromosomal instability and confers a survival and growth advantage to B cells , 2008, Oncogene.

[683]  G. Parmigiani,et al.  Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers , 2008, Proceedings of the National Academy of Sciences.

[684]  Xiaolong Cheng,et al.  ECRG2 Disruption Leads to Centrosome Amplification and Spindle Checkpoint Defects Contributing Chromosome Instability* , 2008, Journal of Biological Chemistry.

[685]  Bela Molnar,et al.  DNA methylation biomarkers for blood-based colorectal cancer screening. , 2008, Clinical chemistry.

[686]  Dao-rong Wang,et al.  Hypermethylated SFRP2 gene in fecal DNA is a high potential biomarker for colorectal cancer noninvasive screening. , 2008, World journal of gastroenterology.

[687]  R. Medema,et al.  Mps1 Phosphorylates Borealin to Control Aurora B Activity and Chromosome Alignment , 2008, Cell.

[688]  T. Yeatman,et al.  HPP1‐mediated tumor suppression requires activation of STAT1 pathways , 2007, International journal of cancer.

[689]  A. Oberg,et al.  Highly Methylated Genes in Colorectal Neoplasia: Implications for Screening , 2007, Cancer Epidemiology Biomarkers & Prevention.

[690]  C. Prigent,et al.  PRP4 is a spindle assembly checkpoint protein required for MPS1, MAD1, and MAD2 localization to the kinetochores , 2007, The Journal of cell biology.

[691]  R. Yung,et al.  The effect of aging and caloric restriction on murine CD8+ T cell chemokine receptor gene expression , 2007, Immunity & Ageing.

[692]  A. Di Leonardo,et al.  Simultaneous Aurora-A/STK15 overexpression and centrosome amplification induce chromosomal instability in tumour cells with a MIN phenotype , 2007, BMC Cancer.

[693]  Kathryn Moynihan Ramsey,et al.  High-fat diet disrupts behavioral and molecular circadian rhythms in mice. , 2007, Cell metabolism.

[694]  A. Tedeschi,et al.  RANBP1 localizes a subset of mitotic regulatory factors on spindle microtubules and regulates chromosome segregation in human cells , 2007, Journal of Cell Science.

[695]  B. Goh,et al.  Detection of promoter hypermethylation in serum samples of cancer patients by methylation-specific polymerase chain reaction for tumour suppressor genes including RUNX3. , 2007, Oncology reports.

[696]  M. Justice,et al.  Overexpression of Eg5 causes genomic instability and tumor formation in mice. , 2007, Cancer research.

[697]  D. Baker,et al.  Bub1 mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesis , 2007, The Journal of cell biology.

[698]  K. Hemminki,et al.  Insulin pathway related genes and risk of colorectal cancer: INSR promoter polymorphism shows a protective effect. , 2007, Endocrine-related cancer.

[699]  S. Groshen,et al.  FCGR2A and FCGR3A polymorphisms associated with clinical outcome of epidermal growth factor receptor expressing metastatic colorectal cancer patients treated with single-agent cetuximab. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[700]  H. Hermeking,et al.  DNA Stool Test for Colorectal Cancer: Hypermethylation of the Secreted Frizzled-Related Protein-1 Gene , 2007, Diseases of the colon and rectum.

[701]  T. Manabe,et al.  Chemokine receptor CXCR3 promotes colon cancer metastasis to lymph nodes , 2007, Oncogene.

[702]  T. Tsukamoto,et al.  Chromosomal instability by β-catenin/TCF transcription in APC or β-catenin mutant cells , 2007, Oncogene.

[703]  R. Muschel,et al.  Tripin/hSgo2 recruits MCAK to the inner centromere to correct defective kinetochore attachments , 2007, The Journal of cell biology.

[704]  W. Leung,et al.  Detection of Hypermethylated DNA or Cyclooxygenase-2 Messenger RNA in Fecal Samples of Patients With Colorectal Cancer or Polyps , 2007, The American Journal of Gastroenterology.

[705]  Naoshi Nishida,et al.  High copy amplification of the aurora-A gene is associated with chromosomal instability phenotype in human colorectal cancers , 2007, Cancer biology & therapy.

[706]  Zhaohui Huang,et al.  Hypermethylation of SFRP2 as a Potential Marker for Stool-Based Detection of Colorectal Cancer and Precancerous Lesions , 2007, Digestive Diseases and Sciences.

[707]  M. Abbaszadegan,et al.  Stool-based DNA testing, a new noninvasive method for colorectal cancer screening, the first report from Iran. , 2007, World journal of gastroenterology.

[708]  Fan Yang,et al.  Detection of aberrant methylation in fecal DNA as a molecular screening tool for colorectal cancer and precancerous lesions. , 2007, World journal of gastroenterology.

[709]  S. Markowitz,et al.  Improved fecal DNA test for colorectal cancer screening. , 2007, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[710]  J. Ward,et al.  Heterozygous deletion of mitotic arrest-deficient protein 1 (MAD1) increases the incidence of tumors in mice. , 2007, Cancer research.

[711]  Cristina Montagna,et al.  Aneuploidy acts both oncogenically and as a tumor suppressor. , 2007, Cancer cell.

[712]  S. Lowe,et al.  Mad2 overexpression promotes aneuploidy and tumorigenesis in mice. , 2007, Cancer cell.

[713]  R. Lamerz,et al.  Methylation of Serum DNA Is an Independent Prognostic Marker in Colorectal Cancer , 2006, Clinical Cancer Research.

[714]  Andrea Musacchio,et al.  Kinetochore Microtubule Dynamics and Attachment Stability Are Regulated by Hec1 , 2006, Cell.

[715]  Jun Luo,et al.  Hypermethylation and expression regulation of secreted frizzled-related protein genes in colorectal tumor. , 2006, World journal of gastroenterology.

[716]  David M. Livingston,et al.  The BRCA1/BARD1 Heterodimer Modulates Ran-Dependent Mitotic Spindle Assembly , 2006, Cell.

[717]  B. Evers,et al.  RNA interference: mechanisms of action and therapeutic consideration. , 2006, Surgery.

[718]  Bela Molnar,et al.  Aristaless-like homeobox-4 gene methylation is a potential marker for colorectal adenocarcinomas. , 2006, Gastroenterology.

[719]  N. Galjart,et al.  Mammalian CLASP1 and CLASP2 cooperate to ensure mitotic fidelity by regulating spindle and kinetochore function. , 2006, Molecular biology of the cell.

[720]  D. Cimini,et al.  Aurora Kinase Promotes Turnover of Kinetochore Microtubules to Reduce Chromosome Segregation Errors , 2006, Current Biology.

[721]  P. Stukenberg,et al.  Aurora B Is Enriched at Merotelic Attachment Sites, Where It Regulates MCAK , 2006, Current Biology.

[722]  T. Misteli,et al.  Tumor Formation via Loss of a Molecular Motor Protein , 2006, Current Biology.

[723]  Chao Zhang,et al.  RNAi technology: a revolutionary tool for the colorectal cancer therapeutics. , 2006, World journal of gastroenterology.

[724]  Yusuke Nakamura,et al.  Identification of TOMM34, which shows elevated expression in the majority of human colon cancers, as a novel drug target. , 2006, International journal of oncology.

[725]  W. Birchmeier,et al.  Aberrant Wnt/beta-catenin signaling can induce chromosomal instability in colon cancer. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[726]  Viji M. Draviam,et al.  Misorientation and reduced stretching of aligned sister kinetochores promote chromosome missegregation in EB1‐ or APC‐depleted cells , 2006, The EMBO journal.

[727]  H. Nagawa,et al.  Overexpression of hRFI inhibits 5-fluorouracil-induced apoptosis in colorectal cancer cells via activation of NF-κB and upregulation of BCL-2 and BCL-XL , 2006, Oncogene.

[728]  Zhong-xin Huang,et al.  Relationship between somatostatin receptor subtype expression and clinicopathology, Ki-67, Bcl-2 and p53 in colorectal cancer. , 2006, World journal of gastroenterology.

[729]  A. Zetterberg,et al.  Separase: a universal trigger for sister chromatid disjunction but not chromosome cycle progression , 2006, The Journal of cell biology.

[730]  Y. Kajiwara,et al.  Monoallelic BUB1B mutations and defective mitotic‐spindle checkpoint in seven families with premature chromatid separation (PCS) syndrome , 2006, American journal of medical genetics. Part A.

[731]  D. Compton,et al.  Efficient Mitosis in Human Cells Lacking Poleward Microtubule Flux , 2005, Current Biology.

[732]  Stephen S. Taylor,et al.  Silencing Cenp-F weakens centromeric cohesion, prevents chromosome alignment and activates the spindle checkpoint , 2005, Journal of Cell Science.

[733]  F. Chan,et al.  Quantitative Detection of Promoter Hypermethylation in Multiple Genes in the Serum of Patients with Colorectal Cancer , 2005, The American Journal of Gastroenterology.

[734]  Patricia Keating,et al.  Inhibition of Single Minded 2 gene expression mediates tumor-selective apoptosis and differentiation in human colon cancer cells. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[735]  P. Sorger,et al.  Generating chromosome instability through the simultaneous deletion of Mad2 and p53. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[736]  L. Myeroff,et al.  Detection in fecal DNA of colon cancer-specific methylation of the nonexpressed vimentin gene. , 2005, Journal of the National Cancer Institute.

[737]  P. Malfertheiner,et al.  Hypermethylation of the TPEF/HPP1 gene in primary and metastatic colorectal cancers. , 2005, Neoplasia.

[738]  T. Tomonaga,et al.  Centromere protein H is up-regulated in primary human colorectal cancer and its overexpression induces aneuploidy. , 2005, Cancer research.

[739]  H. Nagawa,et al.  Overexpression of hRFI (human ring finger homologous to inhibitor of apoptosis protein type) inhibits death receptor–mediated apoptosis in colorectal cancer cells , 2005, Molecular Cancer Therapeutics.

[740]  Hans Clevers,et al.  FoxM1 is required for execution of the mitotic programme and chromosome stability , 2005, Nature Cell Biology.

[741]  A. McLennan,et al.  The Nudix hydrolase superfamily , 2005, Cellular and Molecular Life Sciences CMLS.

[742]  N. Rahman,et al.  Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B , 2004, Nature Genetics.

[743]  W. Gerald,et al.  Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control , 2004, Nature.

[744]  R. Kumar,et al.  BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice , 2004, Nature Genetics.

[745]  D. Ludwig,et al.  DEGA/AMIGO-2, a leucine-rich repeat family member, differentially expressed in human gastric adenocarcinoma: effects on ploidy, chromosomal stability, cell adhesion/migration and tumorigenicity , 2004, Oncogene.

[746]  K. Sakamoto Knocking Down Human Disease: Potential Uses of RNA Interference in Research and Gene Therapy , 2004, Pediatric Research.

[747]  M. Widschwendter,et al.  Methylation changes in faecal DNA: a marker for colorectal cancer screening? , 2004, The Lancet.

[748]  Wei Dong Chen,et al.  Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer , 2004, Nature Genetics.

[749]  Carlo Rago,et al.  Inactivation of hCDC4 can cause chromosomal instability , 2004, Nature.

[750]  Yvonne Wallis,et al.  The Wnt Antagonist sFRP1 in Colorectal Tumorigenesis , 2004, Cancer Research.

[751]  P. Hergert,et al.  Depletion of centromeric MCAK leads to chromosome congression and segregation defects due to improper kinetochore attachments. , 2003, Molecular biology of the cell.

[752]  Z. Darżynkiewicz,et al.  BUBR1 deficiency results in abnormal megakaryopoiesis. , 2003, Blood.

[753]  R. Green,et al.  Chromosome instability in colorectal tumor cells is associated with defects in microtubule plus-end attachments caused by a dominant mutation in APC , 2003, The Journal of cell biology.

[754]  Jiandong Chen,et al.  Overexpressed pituitary tumor-transforming gene causes aneuploidy in live human cells. , 2003, Endocrinology.

[755]  Eiji Sakurai,et al.  An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice , 2003, Nature Medicine.

[756]  Z. Bonday,et al.  Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss , 2003, The Journal of cell biology.

[757]  J. Peters,et al.  The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore–microtubule attachment and in maintaining the spindle assembly checkpoint , 2003, The Journal of cell biology.

[758]  D. Baker,et al.  Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation , 2003, The Journal of cell biology.

[759]  A. Bosserhoff,et al.  The Ets-1 transcription factor is involved in the development and invasion of malignant melanoma , 2003, Cellular and Molecular Life Sciences CMLS.

[760]  S. Turner,et al.  Gleevec (STI-571) inhibits lung cancer cell growth (A549) and potentiates the cisplatin effect in vitro , 2003, Molecular Cancer.

[761]  C. Sweep,et al.  Expression of the transcription factor Ets-1 is an independent prognostic marker for relapse-free survival in breast cancer , 2002, Oncogene.

[762]  A. Giordano,et al.  Cyclin E and chromosome instability in colorectal cancer cell lines , 2002, Molecular pathology : MP.

[763]  A. Parle‐McDermott,et al.  Gene expression differences between the microsatellite instability (MIN) and chromosomal instability (CIN) phenotypes in colorectal cancer revealed by high-density cDNA array hybridization , 2002, Oncogene.

[764]  R. Fodde The APC gene in colorectal cancer. , 2002, European journal of cancer.

[765]  C. Ji,et al.  Cloning and Characterization of a Novel Human Alcohol Dehydrogenase Gene (ADHFe1) , 2002, DNA sequence : the journal of DNA sequencing and mapping.

[766]  S. Narumiya,et al.  Acceleration of intestinal polyposis through prostaglandin receptor EP2 in ApcΔ716 knockout mice , 2001, Nature Medicine.

[767]  L. Sobin,et al.  TNM classification , 2001 .

[768]  Stephen S. Taylor,et al.  Aneuploid colon cancer cells have a robust spindle checkpoint , 2001, EMBO reports.

[769]  Michael R. Speicher,et al.  Securin Is Required for Chromosomal Stability in Human Cells , 2001, Cell.

[770]  T. Nakayama,et al.  Expression of the ets-1 Proto-Oncogene in Human Colorectal Carcinoma , 2001, Modern Pathology.

[771]  H. Clevers,et al.  Mutations in the APC tumour suppressor gene cause chromosomal instability , 2001, Nature Cell Biology.

[772]  M. Duffy,et al.  Carcinoembryonic antigen as a marker for colorectal cancer: is it clinically useful? , 2001, Clinical chemistry.

[773]  W. Gerald,et al.  MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells , 2001, Nature.

[774]  B. Leggett,et al.  HPP1: a transmembrane protein-encoding gene commonly methylated in colorectal polyps and cancers. , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[775]  William M. Grady,et al.  Genomic instability and colorectal cancer , 2006, Current opinion in gastroenterology.

[776]  K. Choo,et al.  Bub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesis. , 2000, Genes & development.

[777]  L. Aaltonen,et al.  The role of hypermethylation of thehMLH1 promoter region in HNPCC versus MSI+ sporadic colorectal cancers , 2000, Journal of medical genetics.

[778]  Yun Zheng,et al.  CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint , 2000, Nature Cell Biology.

[779]  P. Sorger,et al.  Chromosome Missegregation and Apoptosis in Mice Lacking the Mitotic Checkpoint Protein Mad2 , 2000, Cell.

[780]  S. Reed,et al.  Deregulated cyclin E induces chromosome instability , 1999, Nature.

[781]  D. Evans,et al.  Germline E-cadherin gene (CDH1) mutations predispose to familial gastric cancer and colorectal cancer. , 1999, Human molecular genetics.

[782]  R Tenconi,et al.  STK11 mutations in Peutz-Jeghers syndrome and sporadic colon cancer. , 1998, Cancer research.

[783]  M. Wagenbach,et al.  Mitotic Centromere–associated Kinesin Is Important for Anaphase Chromosome Segregation , 1998, The Journal of cell biology.

[784]  J. Jen,et al.  Molecular detection of genetic alterations in the serum of colorectal cancer patients. , 1998, Cancer research.

[785]  Bert Vogelstein,et al.  Mutations of mitotic checkpoint genes in human cancers , 1998, Nature.

[786]  M. Grunstein Histone acetylation in chromatin structure and transcription , 1997, Nature.

[787]  Antonio Facchiano,et al.  The murine Tcl1 oncogene: embryonic and lymphoid cell expression , 1997, Oncogene.

[788]  D. Cimini,et al.  Topoisomerase II inhibition in mitosis produces numerical and structural chromosomal aberrations in human fibroblasts. , 1997, Cytogenetics and cell genetics.

[789]  H Berndt,et al.  [Epidemiology of colorectal cancer]. , 1991, Zeitschrift fur arztliche Fortbildung.

[790]  C. Avnstorp,et al.  Interleukin‐1 , 1987 .

[791]  C. Cooper,et al.  Molecular cloning of a new transforming gene from a chemically transformed human cell line , 1984, Nature.