Fast visual evoked potential input into human area V5

STUDIES of the human visual cortex have demonstrated that an area for motion processing (V5) is located in the lateral occipito-temporal cortex. To study the timing of arrival of signals in V5 we recorded multi-channel visual evoked potentials (VEPs) to checkerboard stimuli. We then applied dipole source analysis which was computed on a grand average of 10 subjects, and on five individual subjects, respectively. We demonstrate an early VEP component with onset before 30 ms and with a peak around 45 ms, located in the vicinity of V5. This early component was independent of a second activity, which started around 50 ms and peaked around 70 ms, and was located within the striate cortex (V1). These results provide further evidence for a very fast input to V5 before activation of V1.

[1]  W. Fries.  The projection from the lateral geniculate nucleus to the prestriate cortex of the macaque monkey , 1981, Proceedings of the Royal Society of London. Series B. Biological Sciences.

[2]  M. Yukie,et al.  Direct projection from the dorsal lateral geniculate nucleus to the prestriate cortex in macaque monkeys , 1981, The Journal of comparative neurology.

[3]  N. Mai,et al.  Selective disturbance of movement vision after bilateral brain damage. , 1983, Brain : a journal of neurology.

[4]  L. Benevento,et al.  The organization of connections between the pulvinar and visual area MT in the macaque monkey , 1983, Brain Research.

[5]  D. Lehmann,et al.  Principles of spatial analysis , 1987 .

[6]  Antoine Rémond,et al.  Methods of Analysis of Brain Electrical and Magnetic Signals , 1987 .

[7]  A. Ducati,et al.  Neuronal generators of the visual evoked potentials: intracerebral recording in awake humans. , 1988, Electroencephalography and clinical neurophysiology.

[8]  B Hjorth,et al.  Principles for Transformation of Scalp EEG from Potential Field into Source Distribution , 1991, Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.

[9]  Dorothy A. Thompson,et al.  Models of the Visual Cortex Based on Visual Evoked Potentials , 1993 .

[10]  E. Marg.  A VISION OF THE BRAIN , 1994 .

[11]  Olaf Dössel,et al.  Possibilities of Functional Brain Imaging Using a Combination of MEG and MRT , 1994 .

[12]  C. N. Guy,et al.  The parallel visual motion inputs into areas V1 and V5 of human cerebral cortex. , 1995, Brain : a journal of neurology.