Characterizing gait asymmetry via frequency sub-band components of the ground reaction force

Abstract This study introduces gait asymmetry measures by comparing the ground reaction force (GRF) features of the left and right limbs. The proposed features were obtained by decomposing the GRF into components of different frequency sub-bands via the wavelet transform. The correlation coefficients between the right and left limb GRF components of the same frequency sub-band were used to characterize the degree of bilateral symmetry. The asymmetry measures were then obtained by subtracting these coefficients from one. To demonstrate the effectiveness of these asymmetry measures, the proposed measures were applied to differentiate the walking patterns of Parkinson's patients and healthy subjects. The results of the statistical analyses found that the patient group has a higher degree of gait asymmetry. By comparing these results with those obtained by conventional asymmetry measures, it was found that the proposed approach can more effectively distinguish the differences between the tested Parkinson's disease patients and the healthy control subjects.

[1]  Jeffrey M. Hausdorff,et al.  Marked alterations in the gait timing and rhythmicity of patients with de novo Parkinson's disease , 2006, The European journal of neuroscience.

[2]  Cara E Stepp,et al.  Relative fundamental frequency during vocal onset and offset in older speakers with and without Parkinson's disease. , 2013, The Journal of the Acoustical Society of America.

[3]  Mohammad Pooyan,et al.  Modeling the gait of normal and Parkinsonian persons for improving the diagnosis , 2012, Neuroscience Letters.

[4]  Rodolfo H. Rodrigo,et al.  Application of Kohonen maps to kinetic analysis of human gait , 2012 .

[5]  E. Saracchi,et al.  Emerging candidate biomarkers for Parkinson's disease: a review. , 2014, Aging and disease.

[6]  Jeffrey M. Hausdorff,et al.  Physionet: Components of a New Research Resource for Complex Physiologic Signals". Circu-lation Vol , 2000 .

[7]  Manuela Galli,et al.  Use of the Gait Deviation Index for the Evaluation of Patients With Parkinson's Disease , 2012, Journal of motor behavior.

[8]  T. Judkins,et al.  Peripheral arterial disease affects the frequency response of ground reaction forces during walking. , 2012, Clinical biomechanics.

[9]  Ray-Yau Wang,et al.  The relation between ankle impairments and gait velocity and symmetry in people with stroke. , 2006, Archives of physical medicine and rehabilitation.

[10]  R. Barker,et al.  Determinants of delayed diagnosis in Parkinson’s disease , 2013, Journal of Neurology.

[11]  C. Tanner,et al.  Clinical features in early Parkinson disease and survival. , 2009, Archives of neurology.

[12]  M. Breteler,et al.  Epidemiology of Parkinson's disease , 2006, The Lancet Neurology.

[13]  Sang-Hong Lee,et al.  Parkinson's disease classification using gait characteristics and wavelet-based feature extraction , 2012, Expert Syst. Appl..

[14]  M. Ebadi,et al.  Biomarkers in Parkinson’s disease (recent update) , 2013, Neurochemistry International.

[15]  Mohammad Reza Daliri,et al.  Chi-square distance kernel of the gaits for the diagnosis of Parkinson's disease , 2013, Biomed. Signal Process. Control..

[16]  R. Djaldetti,et al.  The mystery of motor asymmetry in Parkinson's disease , 2006, The Lancet Neurology.

[17]  Aleksandar Pavic,et al.  Experimental identification and analytical modelling of human walking forces: Literature review , 2009 .

[18]  Kelly A Danks,et al.  Repeated Split-Belt Treadmill Training Improves Poststroke Step Length Asymmetry , 2013, Neurorehabilitation and neural repair.

[19]  F. Su,et al.  Potential of the Genetic Algorithm Neural Network in the Assessment of Gait Patterns in Ankle Arthrodesis , 2004, Annals of Biomedical Engineering.

[20]  Chung Chao Liang,et al.  The efficacy of quantitative gait analysis by the GAITRite system in evaluation of parkinsonian bradykinesia. , 2006, Parkinsonism & related disorders.

[21]  R. White,et al.  Harmonic analysis of force platform data in normal and cerebral palsy gait. , 2005, Clinical biomechanics.

[22]  Jan Bürmann,et al.  Principal Component Analysis of gait in Parkinson's disease: relevance of gait velocity. , 2014, Gait & posture.

[23]  M. Thaut,et al.  Components of EMG symmetry and variability in parkinsonian and healthy elderly gait. , 1996, Electroencephalography and clinical neurophysiology.

[24]  Murray Mp Studies of normal and abnormal locomotion. , 1979 .

[25]  O. Blin,et al.  Quantitative analysis of gait in Parkinson patients: increased variability of stride length , 1990, Journal of the Neurological Sciences.

[26]  Felipe P Carpes,et al.  On the bilateral asymmetry during running and cycling - a review considering leg preference. , 2010, Physical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine.

[27]  J. Winkler,et al.  Unbiased and Mobile Gait Analysis Detects Motor Impairment in Parkinson's Disease , 2013, PloS one.

[28]  E. Montgomery,et al.  Early detection of Parkinson's disease. , 2007, Handbook of clinical neurology.

[29]  J. Summers,et al.  Abnormalities in the stride length‐cadence relation in parkinsonian gait , 1998, Movement disorders : official journal of the Movement Disorder Society.

[30]  D. Twelves,et al.  Systematic review of incidence studies of Parkinson's disease , 2003, Movement disorders : official journal of the Movement Disorder Society.

[31]  J L McCrory,et al.  Vertical ground reaction forces: objective measures of gait following hip arthroplasty. , 2001, Gait & posture.

[32]  J. Duysens,et al.  Quantitative gait analysis in patients with vascular parkinsonism , 1996, Movement disorders : official journal of the Movement Disorder Society.

[33]  Anne Smith,et al.  Basic parameters of articulatory movements and acoustics in individuals with Parkinson's disease , 2012, Movement disorders : official journal of the Movement Disorder Society.

[34]  Jeffrey M. Hausdorff,et al.  Gait asymmetry in patients with Parkinson’s disease and elderly fallers: when does the bilateral coordination of gait require attention? , 2007, Experimental Brain Research.

[35]  Michael Unser,et al.  A review of wavelets in biomedical applications , 1996, Proc. IEEE.

[36]  F. Prince,et al.  Symmetry and limb dominance in able-bodied gait: a review. , 2000, Gait & posture.

[37]  Nicholas Stergiou,et al.  Multiple sclerosis affects the frequency content in the vertical ground reaction forces during walking. , 2011, Clinical biomechanics.

[38]  C. Hass,et al.  Interlimb coordination is impaired during walking in persons with Parkinson's disease. , 2013, Clinical biomechanics.

[39]  A B Dufour,et al.  Functional foot symmetry and its relation to lower extremity physical performance in older adults: the Framingham Foot Study. , 2012, Journal of biomechanics.

[40]  J. Summers,et al.  The pathogenesis of gait hypokinesia in Parkinson's disease. , 1994, Brain : a journal of neurology.

[41]  Dimitrios I. Fotiadis,et al.  Assessment of Tremor Activity in the Parkinson’s Disease Using a Set of Wearable Sensors , 2012, IEEE Transactions on Information Technology in Biomedicine.

[42]  Tong Liu,et al.  Author's Personal Copy Biomedical Signal Processing and Control Effective Detection of Parkinson's Disease Using an Adaptive Fuzzy K-nearest Neighbor Approach , 2022 .

[43]  Ali N. Akansu,et al.  Emerging applications of wavelets: A review , 2010, Phys. Commun..

[44]  Marimuthu Palaniswami,et al.  Automatic Recognition of Gait Patterns Exhibiting Patellofemoral Pain Syndrome Using a Support Vector Machine Approach , 2009, IEEE Transactions on Information Technology in Biomedicine.

[45]  Jeffrey M. Hausdorff,et al.  Gait variability and basal ganglia disorders: Stride‐to‐stride variations of gait cycle timing in parkinson's disease and Huntington's disease , 1998, Movement disorders : official journal of the Movement Disorder Society.

[46]  Kevin Warwick,et al.  Parkinsonian tremor identification with multiple local field potential feature classification , 2012, Journal of Neuroscience Methods.

[47]  Xuemei Huang,et al.  Arm swing magnitude and asymmetry during gait in the early stages of Parkinson's disease. , 2010, Gait & posture.

[48]  H. Katzen,et al.  An accelerometry-based study of lower and upper limb tremor in Parkinson’s disease , 2013, Journal of Clinical Neuroscience.

[49]  Tom Fawcett,et al.  An introduction to ROC analysis , 2006, Pattern Recognit. Lett..

[50]  Mohammad Reza Daliri,et al.  Automatic diagnosis of neuro-degenerative diseases using gait dynamics , 2012 .

[51]  P. Komi,et al.  Gait asymmetry in patients with limb length discrepancy , 2004, Scandinavian journal of medicine & science in sports.