Electroporation Therapy for Head and Neck Cancer Including Carotid Artery Involvement

Objectives Electroporation therapy with intralesional bleomycin (EPT) is a novel, technically simple outpatient technique in which high‐voltage electric impulses delivered into a neoplasm transiently increase cell membrane permeability to large molecules, including cytotoxic agents, causing localized progressive necrosis. Unlike many laser ablation methods, EPT can treat bulky tumors (>2 cm) with complete penetration. Our recent publication confirms an excellent response rate in the use of EPT in a clinical trial.

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