Upper Lid Pilomatricoma: A Report of Four Cases

Purpose: Four patients who presented with an upper lid mass were diagnosed with pilomatricoma after excisional biopsy. We report the cases to improve the differential diagnoses of upper lid masses through investigation of the clinical manifestations and radiological findings of pilomatricoma. Case summary: Three females and one male with ages of six, seven, eight and 46 years, respectively, each presented with a slowly growing and painless upper lid mass of a three-month duration. In the six-year-old patient who had a history of trauma related to the mass, the mass was fixed to the skin, although the masses were movable in the other patients. Upon computed tomography (CT), well-circumscribed, enhancing nodules were found. Excisional biopsy was performed for definite diagnosis and treatment. All completely excised masses were hard and encapsulated with a thin membrane. The sizes of the masses were 12 mm, 10 mm, 10 mm, and 7 mm. Histopathologic examination with hematoxylin-eosin staining confirmed the masses to be pilomatricoma. There was no evidence of recurrence at 16, 2, 19, and 21 months after mass excision. Conclusions: In patients presenting with a painless upper lid mass, pilomatricoma should be considered in the differential diagnosis.

[1]  A. D. De Schepper,et al.  Magnetic resonance imaging of pilomatricoma , 2004, European Radiology.

[2]  D. B. Goufman,et al.  Quiz Case 2 , 2001 .

[3]  K. H. Lee,et al.  Pilomatricoma in the head and neck: CT findings in three patients. , 2000, Journal of computer assisted tomography.

[4]  J. Triglia,et al.  Pilomatrixoma of the head and neck in children: a study of 38 cases and a review of the literature. , 1998, Archives of otolaryngology--head & neck surgery.

[5]  P. W. Bowers,et al.  A clinical review of 209 pilomatricomas. , 1998, Journal of the American Academy of Dermatology.

[6]  J. Shugar,et al.  CT of pilomatrixoma in the cheek. , 1998, AJNR. American journal of neuroradiology.

[7]  K. Ohtomo,et al.  Giant calcifying epithelioma of Malherbe (pilomatrixoma): imaging features , 1997, Skeletal Radiology.

[8]  H. Kerl,et al.  Morphological stages of pilomatricoma. , 1996, The American Journal of dermatopathology.

[9]  D. Brasnu,et al.  Head and neck pilomatrixoma. , 1996, American journal of otolaryngology.

[10]  O'malley Bw Pathologic quiz case 1. Pilomatricoma (calcified epithelioma of Malherbe) with secondary ossification. , 1992 .

[11]  E. Wyatt,et al.  Pilomatricoma (Malherbe) , 1988, International journal of dermatology.

[12]  G. Colver,et al.  Pilomatrixoma An Elusive Diagnosis , 1988, International journal of dermatology.

[13]  G. Rogers,et al.  Pilomatricoma in a pediatric hospital. , 1983, Archives of ophthalmology.

[14]  R. O'Grady,et al.  Pilomatrixoma (benign calcifying epithelioma of Malherbe). , 1981, Ophthalmology.

[15]  M. Abel Elastosis perforans serpiginosa associated with penicillamine. , 1977, Archives of dermatology.

[16]  Headington Jt Tumors of the hair follicle. A review. , 1976 .

[17]  J. Kleener Pilomatrixoma (epithelioma calcificans Malherbe). A clinical and histopathological survey of Danish material from 1954 to 1971. , 2009, Acta ophthalmologica.

[18]  L. Zimmerman,et al.  PILOMATRIXOMA (BENIGN CALCIFYING EPITHELIOMA) OF THE EYELIDS AND EYEBROW. , 1963, Archives of ophthalmology.

[19]  E. B. Helwig,et al.  Pilomatrixoma (calcifying epithelioma). , 1961, Archives of dermatology.

[20]  R. Welch,et al.  Lesions of the lids; a statistical note. , 1958, American journal of ophthalmology-glaucoma.