Inhibition of protein misfolding and aggregation by natural phenolic compounds
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[1] Rahul,et al. Protective Effect of Kaempferol on the Transgenic Drosophila Model of Alzheimer's Disease. , 2018, CNS & neurological disorders drug targets.
[2] M. Bucciantini,et al. Oleuropein aglycone stabilizes the monomeric α-synuclein and favours the growth of non-toxic aggregates , 2018, Scientific Reports.
[3] J. Brender,et al. A blend of two resveratrol derivatives abolishes hIAPP amyloid growth and membrane damage. , 2018, Biochimica et biophysica acta. Biomembranes.
[4] Palak Patel,et al. Inhibition of insulin amyloid fibrillation by Morin hydrate. , 2018, International journal of biological macromolecules.
[5] C. Dyck. Anti-Amyloid-β Monoclonal Antibodies for Alzheimer’s Disease: Pitfalls and Promise , 2018 .
[6] Qiuchen Zheng,et al. Mechanistic Studies of the Inhibition of Insulin Fibril Formation by Rosmarinic Acid. , 2018, Journal of Physical Chemistry B.
[7] H. Fuchs,et al. Epigallocatechin gallate (EGCG) reduces the intensity of pancreatic amyloid fibrils in human islet amyloid polypeptide (hIAPP) transgenic mice , 2018, Scientific Reports.
[8] G. Bifulco,et al. Down regulation of pro‐inflammatory pathways by tanshinone IIA and cryptotanshinone in a non‐genetic mouse model of Alzheimer's disease , 2017, Pharmacological research.
[9] Xiaoyan Dong,et al. Brazilin Inhibits Prostatic Acidic Phosphatase Fibrillogenesis and Decreases its Cytotoxicity. , 2017, Chemistry, an Asian journal.
[10] Myeong Ok Kim,et al. Neuroprotective Effect of Fisetin Against Amyloid-Beta-Induced Cognitive/Synaptic Dysfunction, Neuroinflammation, and Neurodegeneration in Adult Mice , 2017, Molecular Neurobiology.
[11] J. Pantel,et al. Impact of Resveratrol on Glucose Control, Hippocampal Structure and Connectivity, and Memory Performance in Patients with Mild Cognitive Impairment , 2017, Front. Neurosci..
[12] Yu Zhang,et al. Resveratrol ameliorates spatial learning memory impairment induced by Aβ1–42 in rats , 2017, Neuroscience.
[13] A. Neves,et al. Resveratrol and Grape Extract-loaded Solid Lipid Nanoparticles for the Treatment of Alzheimer’s Disease , 2017, Molecules.
[14] R. He,et al. Resveratrol Attenuates Formaldehyde Induced Hyperphosphorylation of Tau Protein and Cytotoxicity in N2a Cells , 2017, Frontiers in neuroscience.
[15] Robert H. Brown,et al. Decoding ALS: from genes to mechanism , 2016, Nature.
[16] Claudio Soto,et al. Molecular interaction between type 2 diabetes and Alzheimer’s disease through cross-seeding of protein misfolding , 2016, Molecular Psychiatry.
[17] Wei Zhang,et al. Morin reverses neuropathological and cognitive impairments in APPswe/PS1dE9 mice by targeting multiple pathogenic mechanisms , 2016, Neuropharmacology.
[18] M. Ramazzotti,et al. Mechanisms for the inhibition of amyloid aggregation by small ligands , 2016, Bioscience reports.
[19] A. Lavecchia,et al. The 37/67kDa laminin receptor (LR) inhibitor, NSC47924, affects 37/67kDa LR cell surface localization and interaction with the cellular prion protein , 2016, Scientific Reports.
[20] Wei-Yun Wang,et al. A Novel Multifunctional Compound Camellikaempferoside B Decreases Aβ Production, Interferes with Aβ Aggregation, and Prohibits Aβ-Mediated Neurotoxicity and Neuroinflammation. , 2016, ACS chemical neuroscience.
[21] Jie Xu,et al. Quercetin Protects against Okadaic Acid-Induced Injury via MAPK and PI3K/Akt/GSK3β Signaling Pathways in HT22 Hippocampal Neurons , 2016, PloS one.
[22] M. Lee,et al. Perilla frutescens var. japonica and rosmarinic acid improve amyloid-β25-35 induced impairment of cognition and memory function , 2016, Nutrition research and practice.
[23] S. Doglia,et al. The polyphenol Oleuropein aglycone hinders the growth of toxic transthyretin amyloid assemblies. , 2016, The Journal of nutritional biochemistry.
[24] Yi Sun,et al. Neuroprotective Effects of A Standardized Flavonoid Extract of Safflower Against Neurotoxin-Induced Cellular and Animal Models of Parkinson’s Disease , 2016, Scientific Reports.
[25] Tara Pukala,et al. Bioactive polyphenol interactions with β amyloid: a comparison of binding modelling, effects on fibril and aggregate formation and neuroprotective capacity. , 2016, Food & function.
[26] M. C. Graber,et al. Stabilization of α-Synuclein Fibril Clusters Prevents Fragmentation and Reduces Seeding Activity and Toxicity. , 2016, Biochemistry.
[27] Kun Huang,et al. Inhibition effects of tanshinone on the aggregation of α-synuclein. , 2016, Food & function.
[28] Thomas P. Davis,et al. Stabilizing Off-pathway Oligomers by Polyphenol Nanoassemblies for IAPP Aggregation Inhibition , 2016, Scientific Reports.
[29] H. Zhao,et al. Resveratrol decreases the insoluble Aβ1–42 level in hippocampus and protects the integrity of the blood–brain barrier in AD rats , 2015, Neuroscience.
[30] C. Fierke,et al. Inhibition of IAPP Aggregation and Toxicity by Natural Products and Derivatives , 2015, Journal of diabetes research.
[31] B. Bano,et al. Evaluation of polyphenols as possible therapeutics for amyloidoses: Comparative analysis of Kaempferol and Catechin. , 2015, International journal of biological macromolecules.
[32] James B. Brewer,et al. A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease , 2015, Neurology.
[33] D. Del Rio,et al. Transthyretin Binding Heterogeneity and Anti-amyloidogenic Activity of Natural Polyphenols and Their Metabolites* , 2015, The Journal of Biological Chemistry.
[34] Duilio Cascio,et al. Uncovering the Mechanism of Aggregation of Human Transthyretin , 2015, The Journal of Biological Chemistry.
[35] Ling Yan,et al. Resveratrol inhibits oligomeric Aβ-induced microglial activation via NADPH oxidase. , 2015, Molecular medicine reports.
[36] T. Mohamed,et al. Curcumin Binding to Beta Amyloid: A Computational Study , 2015, Chemical biology & drug design.
[37] J. Keller,et al. Oleocanthal Enhances Amyloid-β Clearance from the Brains of TgSwDI Mice and in Vitro across a Human Blood-Brain Barrier Model , 2015, ACS chemical neuroscience.
[38] Sharmistha Banerjee,et al. The beneficial role of curcumin on inflammation, diabetes and neurodegenerative disease: A recent update. , 2015, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[39] A. Ghasemi,et al. Inhibition of amyloid fibrillation and cytotoxicity of lysozyme fibrillation products by polyphenols. , 2015, International journal of biological macromolecules.
[40] H. Nishijo,et al. Phenolic compounds prevent the oligomerization of α‐synuclein and reduce synaptic toxicity , 2015, Journal of neurochemistry.
[41] Amir S. Sharili,et al. In Vitro Activity of Epigallocatechin Gallate and Quercetin Alone and in Combination versus Clinical Isolates of Methicillin-Resistant Staphylococcus aureus. , 2015, Journal of natural products.
[42] Claudio Soto,et al. Type 2 diabetes as a protein misfolding disease. , 2015, Trends in molecular medicine.
[43] L. Leal,et al. Neuroprotective Properties of the Standardized Extract from Camellia sinensis (Green Tea) and Its Main Bioactive Components, Epicatechin and Epigallocatechin Gallate, in the 6-OHDA Model of Parkinson's Disease , 2015, Evidence-based complementary and alternative medicine : eCAM.
[44] C. Meshul,et al. Curcumin Treatment Improves Motor Behavior in α-Synuclein Transgenic Mice , 2015, PloS one.
[45] E. Sigurdsson,et al. Tau immunotherapy for Alzheimer's disease. , 2015, Trends in molecular medicine.
[46] J. R. Ramírez-Pineda,et al. The flavonoid quercetin ameliorates Alzheimer's disease pathology and protects cognitive and emotional function in aged triple transgenic Alzheimer's disease model mice , 2015, Neuropharmacology.
[47] A. Surolia,et al. Curcumin Pyrazole and its derivative (N-(3-Nitrophenylpyrazole) Curcumin inhibit aggregation, disrupt fibrils and modulate toxicity of Wild type and Mutant α-Synuclein , 2015, Scientific Reports.
[48] M. Lotz,et al. Transthyretin Deposition in Articular Cartilage: A Novel Mechanism in the Pathogenesis of Osteoarthritis , 2015, Arthritis & rheumatology.
[49] Xi Zheng,et al. Curcumin, Inflammation, and Chronic Diseases: How Are They Linked? , 2015, Molecules.
[50] E. Wanker,et al. Modulation of human IAPP fibrillation: cosolutes, crowders and chaperones. , 2015, Physical chemistry chemical physics : PCCP.
[51] Thomas Wisniewski,et al. Immunotherapeutic Approaches for Alzheimer’s Disease , 2015, Neuron.
[52] D. Milardi,et al. Resveratrol interferes with the aggregation of membrane-bound human-IAPP: a molecular dynamics study. , 2015, European journal of medicinal chemistry.
[53] M. Stefani,et al. Oleuropein aglycone protects against pyroglutamylated-3 amyloid-ß toxicity: biochemical, epigenetic and functional correlates , 2015, Neurobiology of Aging.
[54] M. Fändrich,et al. AA Amyloidosis : Pathogenesis and Targeted Therapy Gunilla , 2014 .
[55] Shaoyi Jiang,et al. Brazilin inhibits amyloid β-protein fibrillogenesis, remodels amyloid fibrils and reduces amyloid cytotoxicity , 2015, Scientific Reports.
[56] Y. Sekijima. Transthyretin (ATTR) amyloidosis: clinical spectrum, molecular pathogenesis and disease-modifying treatments , 2015, Journal of Neurology, Neurosurgery & Psychiatry.
[57] Huanxiang Liu,et al. Molecular mechanism of the inhibition and remodeling of human islet amyloid polypeptide (hIAPP(1-37)) oligomer by resveratrol from molecular dynamics simulation. , 2015, The journal of physical chemistry. B.
[58] E. Wanker,et al. The green tea polyphenol (−)‐epigallocatechin gallate prevents the aggregation of tau protein into toxic oligomers at substoichiometric ratios , 2015, FEBS letters.
[59] Y. Li,et al. Quercetin protects human brain microvascular endothelial cells from fibrillar β-amyloid1–40-induced toxicity , 2015, Acta pharmaceutica Sinica. B.
[60] S. Radford,et al. Mutational Analysis of the Ability of Resveratrol To Inhibit Amyloid Formation by Islet Amyloid Polypeptide: Critical Evaluation of the Importance of Aromatic–Inhibitor and Histidine–Inhibitor Interactions , 2014, Biochemistry.
[61] A. Segura‐Carretero,et al. Pine Bark and Green Tea Concentrated Extracts: Antioxidant Activity and Comprehensive Characterization of Bioactive Compounds by HPLC–ESI-QTOF-MS , 2014, International journal of molecular sciences.
[62] G. Shanmugam,et al. Gallic acid, one of the components in many plant tissues, is a potential inhibitor for insulin amyloid fibril formation. , 2014, European journal of medicinal chemistry.
[63] Gary W. Jones,et al. Myricetin prevents fibrillogenesis of hen egg white lysozyme. , 2014, Journal of agricultural and food chemistry.
[64] J. Carver,et al. Gallic acid interacts with α-synuclein to prevent the structural collapse necessary for its aggregation. , 2014, Biochimica et biophysica acta.
[65] W. Rosenblum. Why Alzheimer trials fail: removing soluble oligomeric beta amyloid is essential, inconsistent, and difficult , 2014, Neurobiology of Aging.
[66] Falaq Naz,et al. Effect of Curcumin on Lifespan, Activity Pattern, Oxidative Stress, and Apoptosis in the Brains of Transgenic Drosophila Model of Parkinson's Disease , 2014, BioMed research international.
[67] Li Yan,et al. A simple high-performance liquid chromatographic method for the determination of brazilin and its application to a pharmacokinetic study in rats. , 2014, Journal of ethnopharmacology.
[68] P. Maher,et al. Modulation of p25 and inflammatory pathways by fisetin maintains cognitive function in Alzheimer’s disease transgenic mice , 2013, Aging cell.
[69] Danielle M. Williams,et al. Gallic acid is the major component of grape seed extract that inhibits amyloid fibril formation. , 2013, Bioorganic & medicinal chemistry letters.
[70] C. Soto,et al. Role of Protein Misfolding and Proteostasis Deficiency in Protein Misfolding Diseases and Aging , 2013, International journal of cell biology.
[71] C. Park,et al. Effects of brussels sprouts and their phytochemical components on oxidative stress-induced neuronal damages in PC12 cells and ICR mice. , 2013, Journal of medicinal food.
[72] M. Stefani,et al. Employing Alzheimer Disease Animal Models for Translational Research: Focus on Dietary Components , 2013, Neurodegenerative Diseases.
[73] A. Pilarski,et al. Hippocampal neurogenesis in Alzheimer's disease: is there a role for dietary modulation? , 2013, Journal of Alzheimer's disease : JAD.
[74] R. Yazdanparast,et al. Apigenin reduces human insulin fibrillation in vitro and protects SK-N-MC cells against insulin amyloids. , 2013, International journal of biological macromolecules.
[75] C. Soto,et al. Cross-Seeding of Misfolded Proteins: Implications for Etiology and Pathogenesis of Protein Misfolding Diseases , 2013, PLoS pathogens.
[76] M. Stefani,et al. The Polyphenol Oleuropein Aglycone Protects TgCRND8 Mice against Aß Plaque Pathology , 2013, PloS one.
[77] Rui Liu,et al. Neuroprotective, Anti-Amyloidogenic and Neurotrophic Effects of Apigenin in an Alzheimer’s Disease Mouse Model , 2013, Molecules.
[78] Cheng-I Lee,et al. Curcumin Reduces Amyloid Fibrillation of Prion Protein and Decreases Reactive Oxidative Stress , 2013, Pathogens.
[79] A. Wen,et al. Application of a liquid chromatography-tandem mass spectrometry method to the pharmacokinetics, tissue distribution and excretion studies of brazilin in rats. , 2013, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
[80] E. Masliah,et al. Immunotherapy for neurodegenerative diseases: focus on α-synucleinopathies. , 2013, Pharmacology & therapeutics.
[81] Qingqiang Yao,et al. A validated LC-MS/MS method for rapid determination of brazilin in rat plasma and its application to a pharmacokinetic study. , 2013, Biomedical chromatography : BMC.
[82] M. Taghizadeh,et al. Iranian medicinal plants for diabetes mellitus: a systematic review. , 2013, Pakistan journal of biological sciences : PJBS.
[83] Claudia Durán-Aniotz,et al. [Amyloid aggregates: role in Protein Misfolding Disorders]. , 2013, Revista médica de Chile (Impresa).
[84] Min Zhu,et al. Oxidized quercetin inhibits α-synuclein fibrillization. , 2013, Biochimica et biophysica acta.
[85] Jie Zheng,et al. Tanshinones inhibit amyloid aggregation by amyloid-β peptide, disaggregate amyloid fibrils, and protect cultured cells. , 2013, ACS chemical neuroscience.
[86] M. Stefani,et al. Oleuropein Aglycone Protects Transgenic C. elegans Strains Expressing Aβ42 by Reducing Plaque Load and Motor Deficit , 2013, PloS one.
[87] D. Moffet,et al. IAPP aggregation and cellular toxicity are inhibited by 1,2,3,4,6-penta-O-galloyl-β-d-glucose , 2013, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.
[88] G. Pasinetti,et al. Identification of brain‐targeted bioactive dietary quercetin‐3‐O‐glucuronide as a novel intervention for Alzheimer's disease , 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[89] Jiang-Ning Zhou,et al. The binding of resveratrol to monomer and fibril amyloid beta , 2012, Neurochemistry International.
[90] A. Fallarero,et al. Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine. , 2012, Bioorganic & Medicinal Chemistry.
[91] Sung-Hoon Kim,et al. Tanshinones: Sources, Pharmacokinetics and Anti-Cancer Activities , 2012, International journal of molecular sciences.
[92] B. Hyman,et al. The synaptic accumulation of hyperphosphorylated tau oligomers in Alzheimer disease is associated with dysfunction of the ubiquitin-proteasome system. , 2012, The American journal of pathology.
[93] Justin A. Lemkul,et al. Morin inhibits the early stages of amyloid β-peptide aggregation by altering tertiary and quaternary interactions to produce "off-pathway" structures. , 2012, Biochemistry.
[94] S. Thuret,et al. The Role of Dietary Polyphenols on Adult Hippocampal Neurogenesis: Molecular Mechanisms and Behavioural Effects on Depression and Anxiety , 2012, Oxidative medicine and cellular longevity.
[95] D. Moffet,et al. Myricetin Inhibits Islet Amyloid Polypeptide (IAPP) Aggregation and Rescues Living Mammalian Cells from IAPP Toxicity , 2012, The open biochemistry journal.
[96] Samuel Sparks,et al. Curcumin modulates the self-assembly of the islet amyloid polypeptide by disassembling α-helix. , 2012, Biochemical and biophysical research communications.
[97] M. Saraiva,et al. Natural polyphenols as modulators of TTR amyloidogenesis: in vitro and in vivo evidences towards therapy , 2012, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.
[98] B. Caughey,et al. Assessment of Prospective Preventive Therapies for Chronic Wasting Disease in Mule Deer , 2012, Journal of wildlife diseases.
[99] D. Raleigh,et al. Analysis of the inhibition and remodeling of islet amyloid polypeptide amyloid fibers by flavanols. , 2012, Biochemistry.
[100] H. Nishijo,et al. Phenolic compounds prevent beta-amyloid-protein oligomerization and synaptic dysfunction by site-specific binding , 2012, Alzheimer's & Dementia.
[101] D. Raleigh,et al. Morin hydrate inhibits amyloid formation by islet amyloid polypeptide and disaggregates amyloid fibers , 2012, Protein science : a publication of the Protein Society.
[102] S. Tabrizi,et al. Misfolded PrP and a novel mechanism of proteasome inhibition , 2012, Prion.
[103] K. Lu,et al. Resveratrol Protects Rats from Aβ-induced Neurotoxicity by the Reduction of iNOS Expression and Lipid Peroxidation , 2011, PloS one.
[104] M. Bucciantini,et al. Aβ(1-42) aggregates into non-toxic amyloid assemblies in the presence of the natural polyphenol oleuropein aglycon. , 2011, Current Alzheimer research.
[105] Y. Mou,et al. Cryptotanshinione Inhibits β-Amyloid Aggregation and Protects Damage from β-Amyloid in SH-SY5Y Cells , 2011, Neurochemical Research.
[106] Antonia Gutierrez,et al. Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer’s mice hippocampus , 2011, Acta Neuropathologica.
[107] J. Terao,et al. Accumulation of orally administered quercetin in brain tissue and its antioxidative effects in rats. , 2011, Free radical biology & medicine.
[108] D. Mereles,et al. Epigallocatechin-3-gallate (EGCG) for Clinical Trials: More Pitfalls than Promises? , 2011, International journal of molecular sciences.
[109] M. Saraiva,et al. Natural polyphenols inhibit different steps of the process of transthyretin (TTR) amyloid fibril formation , 2011, FEBS letters.
[110] Claudio Soto,et al. Misfolded protein aggregates: mechanisms, structures and potential for disease transmission. , 2011, Seminars in cell & developmental biology.
[111] G. Lippens,et al. Oleuropein and derivatives from olives as Tau aggregation inhibitors , 2011, Neurochemistry International.
[112] Huijun Sun,et al. Apigenin Isolated from the Medicinal Plant Elsholtzia rugulosa Prevents β-Amyloid 25–35-Induces Toxicity in Rat Cerebral Microvascular Endothelial Cells , 2011, Molecules.
[113] A. Giese,et al. Inhibition and disaggregation of α‐synuclein oligomers by natural polyphenolic compounds , 2011, FEBS letters.
[114] J. Collinge,et al. Rapid cell-surface prion protein conversion revealed using a novel cell system , 2011, Nature communications.
[115] Joan-Emma Shea,et al. Resveratrol inhibits the formation of multiple-layered β-sheet oligomers of the human islet amyloid polypeptide segment 22-27. , 2011, Biophysical journal.
[116] Hong-Guang Jin,et al. Biflavonoids are superior to monoflavonoids in inhibiting amyloid-β toxicity and fibrillogenesis via accumulation of nontoxic oligomer-like structures. , 2011, Biochemistry.
[117] C. Ross,et al. Huntington's disease: from molecular pathogenesis to clinical treatment , 2011, The Lancet Neurology.
[118] D. Hinton,et al. Protein Kinase C-Regulated Aβ Production and Clearance , 2011, International journal of Alzheimer's disease.
[119] J. Purcell,et al. ERK activation by the polyphenols fisetin and resveratrol provides neuroprotection in multiple models of Huntington's disease. , 2011, Human molecular genetics.
[120] M. Chan-Park,et al. The Molecular Basis of Distinct Aggregation Pathways of Islet Amyloid Polypeptide* , 2010, The Journal of Biological Chemistry.
[121] R. Tsao. Chemistry and Biochemistry of Dietary Polyphenols , 2010, Nutrients.
[122] M. Clifford,et al. Bioavailability of dietary flavonoids and phenolic compounds. , 2010, Molecular aspects of medicine.
[123] J. Dordick,et al. Aromatic Small Molecules Remodel Toxic Soluble Oligomers of Amyloid β through Three Independent Pathways* , 2010, The Journal of Biological Chemistry.
[124] P. Butler,et al. The effect of curcumin on human islet amyloid polypeptide misfolding and toxicity , 2010, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.
[125] M. Bucciantini,et al. Oleuropein aglycon prevents cytotoxic amyloid aggregation of human amylin. , 2010, Journal of Nutritional Biochemistry.
[126] D. Westaway,et al. Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations , 2010, Cell.
[127] J. Dordick,et al. Resveratrol Selectively Remodels Soluble Oligomers and Fibrils of Amyloid Aβ into Off-pathway Conformers* , 2010, The Journal of Biological Chemistry.
[128] K. Wada,et al. Relationship between the tautomeric structures of curcumin derivatives and their Abeta-binding activities in the context of therapies for Alzheimer's disease. , 2010, Biomaterials.
[129] D. Ehrnhoefer,et al. EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity , 2010, Proceedings of the National Academy of Sciences.
[130] Rodrigo Morales,et al. Molecular Cross Talk between Misfolded Proteins in Animal Models of Alzheimer's and Prion Diseases , 2010, The Journal of Neuroscience.
[131] M. D'Archivio,et al. Bioavailability of the Polyphenols: Status and Controversies , 2010, International journal of molecular sciences.
[132] H. Katus,et al. Effects of the main green tea polyphenol epigallocatechin-3-gallate on cardiac involvement in patients with AL amyloidosis , 2010, Clinical Research in Cardiology.
[133] Chang-Ju Kim,et al. Protective Effects of Kaempferol (3,4′,5,7-tetrahydroxyflavone) against Amyloid Beta Peptide (Aβ)-Induced Neurotoxicity in ICR Mice , 2010, Bioscience, biotechnology, and biochemistry.
[134] A. Murase,et al. Phenolic compounds prevent Alzheimer's pathology through different effects on the amyloid-beta aggregation pathway. , 2009, The American journal of pathology.
[135] Lei Huang,et al. Resveratrol inhibits beta-amyloid oligomeric cytotoxicity but does not prevent oligomer formation. , 2009, Neurotoxicology.
[136] W. Klein,et al. Alzheimer's-associated Abeta oligomers show altered structure, immunoreactivity and synaptotoxicity with low doses of oleocanthal. , 2009, Toxicology and applied pharmacology.
[137] Jeffrey B. Sperry,et al. Inhibition of tau fibrillization by oleocanthal via reaction with the amino groups of tau , 2009, Journal of neurochemistry.
[138] S. Maeda,et al. A traditional medicinal herb Paeonia suffruticosa and its active constituent 1,2,3,4,6‐penta‐O‐galloyl‐β‐d‐glucopyranose have potent anti‐aggregation effects on Alzheimer’s amyloid β proteins in vitro and in vivo , 2009, Journal of neurochemistry.
[139] C. Zurzolo,et al. Identification of an Intracellular Site of Prion Conversion , 2009, PLoS pathogens.
[140] L Bravo,et al. Polyphenols: chemistry, dietary sources, metabolism, and nutritional significance. , 2009, Nutrition reviews.
[141] Marie-Claude Potier,et al. Classification and basic pathology of Alzheimer disease , 2009, Acta Neuropathologica.
[142] Roland Winter,et al. Inhibiting Islet Amyloid Polypeptide Fibril Formation by the Red Wine Compound Resveratrol , 2009, Chembiochem : a European journal of chemical biology.
[143] M. Beal,et al. Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease , 2009, Neurochemistry International.
[144] Kumiko Sakai-Kato,et al. Structural requirements for the flavonoid fisetin in inhibiting fibril formation of amyloid β protein , 2008, Neuroscience Letters.
[145] R. Nixon,et al. Neurodegenerative lysosomal disorders: A continuum from development to late age , 2008, Autophagy.
[146] D. Ehrnhoefer,et al. EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers , 2008, Nature Structural &Molecular Biology.
[147] Iva Hafner-Bratkovič,et al. Curcumin binds to the α‐helical intermediate and to the amyloid form of prion protein – a new mechanism for the inhibition of PrPSc accumulation , 2008 .
[148] V. Mok,et al. Six-month randomized, placebo-controlled, double-blind, pilot clinical trial of curcumin in patients with Alzheimer disease. , 2008, Journal of clinical psychopharmacology.
[149] William C. Nolan,et al. Curcumin inhibits aggregation of α-synuclein , 2008, Acta Neuropathologica.
[150] Fabrizio Chiti,et al. Prevention of amyloid‐like aggregation as a driving force of protein evolution , 2007, EMBO reports.
[151] R. Kayed,et al. Small Molecule Inhibitors of Aggregation Indicate That Amyloid β Oligomerization and Fibrillization Pathways Are Independent and Distinct* , 2007, Journal of Biological Chemistry.
[152] Susan Lindquist,et al. Green tea (-)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models. , 2006, Human molecular genetics.
[153] L. Estrada,et al. Inhibition of protein misfolding and aggregation by small rationally-designed peptides. , 2006, Current pharmaceutical design.
[154] Angelo A. Izzo,et al. The Spice Sage and Its Active Ingredient Rosmarinic Acid Protect PC12 Cells from Amyloid-β Peptide-Induced Neurotoxicity , 2006, Journal of Pharmacology and Experimental Therapeutics.
[155] Kenjiro Ono,et al. Antioxidant compounds have potent anti‐fibrillogenic and fibril‐destabilizing effects for α‐synuclein fibrils in vitro , 2006, Journal of neurochemistry.
[156] Claudio Soto,et al. Amyloids, prions and the inherent infectious nature of misfolded protein aggregates. , 2006, Trends in biochemical sciences.
[157] B. Caughey,et al. Comparison of protease-resistant prion protein inhibitors in cell cultures infected with two strains of mouse and sheep scrapie , 2005, Neuroscience Letters.
[158] Peter Davies,et al. Resveratrol Promotes Clearance of Alzheimer's Disease Amyloid-β Peptides* , 2005, Journal of Biological Chemistry.
[159] Byeoung-Soo Park,et al. Effects of naturally occurring compounds on fibril formation and oxidative stress of beta-amyloid. , 2005, Journal of agricultural and food chemistry.
[160] Robert A. Grothe,et al. Structure of the cross-β spine of amyloid-like fibrils , 2005, Nature.
[161] Christian Néri,et al. Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons , 2005, Nature Genetics.
[162] Takeshi Iwatsubo,et al. Inhibition of Heparin-induced Tau Filament Formation by Phenothiazines, Polyphenols, and Porphyrins* , 2005, Journal of Biological Chemistry.
[163] Fusheng Yang,et al. Curcumin Inhibits Formation of Amyloid β Oligomers and Fibrils, Binds Plaques, and Reduces Amyloid in Vivo* , 2005, Journal of Biological Chemistry.
[164] M. Stefani. Protein misfolding and aggregation: new examples in medicine and biology of the dark side of the protein world. , 2004, Biochimica et biophysica acta.
[165] K. Ono,et al. Anti-amyloidogenic activity of tannic acid and its activity to destabilize Alzheimer's beta-amyloid fibrils in vitro. , 2004, Biochimica et biophysica acta.
[166] J. Nutt,et al. Parkinson's disease , 2004, The Lancet.
[167] M. Lean,et al. HPLC-MSn analysis of phenolic compounds and purine alkaloids in green and black tea. , 2004, Journal of agricultural and food chemistry.
[168] Kenjiro Ono,et al. Curcumin has potent anti‐amyloidogenic effects for Alzheimer's β‐amyloid fibrils in vitro , 2004, Journal of neuroscience research.
[169] B. Caughey,et al. New Inhibitors of Scrapie-Associated Prion Protein Formation in a Library of 2,000 Drugs and Natural Products , 2003, Journal of Virology.
[170] Peter Bross,et al. Protein misfolding and disease : principles and protocols , 2003 .
[171] G. J. Raymond,et al. Inhibition of Protease-Resistant Prion Protein Accumulation In Vitro by Curcumin , 2003, Journal of Virology.
[172] Peter K. T. Pang,et al. The establishment of a reliable cytotoxic system with SK-N-SH neuroblastoma cell culture , 2003, Journal of Neuroscience Methods.
[173] C. Soto,et al. Protein misfolding and disease; protein refolding and therapy , 2001, FEBS letters.
[174] Wenhua Zheng,et al. Effects of amyloid peptides on cell viability and expression of neuropeptides in cultured rat dorsal root ganglion neurons: a role for free radicals and protein kinase C , 2001, The European journal of neuroscience.
[175] James C. Sacchettini,et al. Rational design of potent human transthyretin amyloid disease inhibitors , 2000, Nature Structural Biology.
[176] C. Dobson. Protein misfolding, evolution and disease. , 1999, Trends in biochemical sciences.
[177] W. Schaffner,et al. Phytoestrogen kaempferol (3,4′,5,7‐tetrahydroxyflavone) protects PC12 and T47D cells from β‐amyloid–induced toxicity , 1999, Journal of neuroscience research.
[178] Claudio Soto,et al. β-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: Implications for Alzheimer's therapy , 1998, Nature Medicine.
[179] J. Kelly,et al. Alternative conformations of amyloidogenic proteins govern their behavior. , 1996, Current opinion in structural biology.
[180] P. Lansbury,et al. Seeding “one-dimensional crystallization” of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie? , 1993, Cell.
[181] J. Herbert,et al. Chelerythrine is a potent and specific inhibitor of protein kinase C. , 1990, Biochemical and biophysical research communications.
[182] K. Ono,et al. Natural Phenolic Compounds as Therapeutic and Preventive Agents for Cerebral Amyloidosis. , 2015, Advances in experimental medicine and biology.
[183] J. del Valle,et al. Neuroprotective role of trans-resveratrol in a murine model of familial Alzheimer's disease. , 2014, Journal of Alzheimer's disease : JAD.
[184] M. Saraiva,et al. Dietary curcumin counteracts extracellular transthyretin deposition: insights on the mechanism of amyloid inhibition. , 2013, Biochimica et biophysica acta.
[185] E. Tsilibary,et al. Oleuropein, an Anti-oxidant Polyphenol Constituent of Olive Promotes α-Secretase Cleavage of the Amyloid Precursor Protein (AβPP) , 2012, Cellular and Molecular Neurobiology.
[186] Michael R. Schmidt,et al. Small-molecule conversion of toxic oligomers to nontoxic β-sheet-rich amyloid fibrils. , 2011, Nature chemical biology.
[187] K. Markides,et al. Study of the interaction between the amyloid beta peptide (1-40) and antioxidant compounds by nuclear magnetic resonance spectroscopy. , 2011, Biopolymers.
[188] Masaki Wakabayashi,et al. Inhibitors of amyloid beta-protein aggregation mediated by GM1-containing raft-like membranes. , 2007, Biochimica et biophysica acta.
[189] C. Hetz,et al. Protein misfolding and disease: the case of prion disorders , 2003, Cellular and Molecular Life Sciences CMLS.
[190] Claudio Soto,et al. Unfolding the role of protein misfolding in neurodegenerative diseases , 2003, Nature Reviews Neuroscience.